IMP

Process View

Rattus norvegicus

3 genes annotated in rat

mesenchymal to epithelial transition

A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesenchymal to epithelial transition"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesenchymal to epithelial transition" (in gray)

Name	Description	Probability	Func Analog Organism
LOC100365106	rCG32755-like	0.478
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.330
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.146
Tpsb2	tryptase beta 2	0.121
Rara	retinoic acid receptor, alpha	0.094
Parp14	poly (ADP-ribose) polymerase family, member 14	0.089
LOC100362108	poly (ADP-ribose) polymerase family, member 10	0.086
Sp110	SP110 nuclear body protein	0.084
Rnf213	ring finger protein 213	0.079
Hoxc4	homeo box C4	0.072
Irf7	interferon regulatory factor 7	0.071
Ddr1	discoidin domain receptor tyrosine kinase 1	0.068
Igf2	insulin-like growth factor 2	0.062
Dtx3l	deltex 3-like (Drosophila)	0.047
Unc5b	unc-5 homolog B (C. elegans)	0.046
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.045
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.042
Rxra	retinoid X receptor alpha	0.041
Ltbp3	latent transforming growth factor beta binding protein 3	0.040
Stat2	signal transducer and activator of transcription 2	0.035	Rat
Prdm2	PR domain containing 2, with ZNF domain	0.034
Tgfbr2	transforming growth factor, beta receptor II	0.034
Ifi35	interferon-induced protein 35	0.033
Fut4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.032
Jund	jun D proto-oncogene	0.031
Hist1h1d	histone cluster 1, H1d	0.030
Stat1	signal transducer and activator of transcription 1	0.030
Nos3	nitric oxide synthase 3, endothelial cell	0.029
Gata3	GATA binding protein 3	0.028	Human
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.027
Gpr176	G protein-coupled receptor 176	0.027
Pank2	pantothenate kinase 2 (Hallervorden-Spatz syndrome)	0.026
Bmp7	bone morphogenetic protein 7	0.026
Art2	ADP-ribosyltransferase 2	0.025
Efnb1	ephrin B1	0.023
Irs1	insulin receptor substrate 1	0.023
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.023
Il6st	interleukin 6 signal transducer	0.023
Rassf9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.023
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.023
Cish	cytokine inducible SH2-containing protein	0.022
RGD1305793	similar to hypothetical protein FLJ20154	0.022
Limd1	LIM domains containing 1	0.022
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.022
Csf1	colony stimulating factor 1 (macrophage)	0.022
Trim5	tripartite motif-containing 5	0.021
Smad1	SMAD family member 1	0.021
Igtp	interferon gamma induced GTPase	0.021
Acacb	acetyl-Coenzyme A carboxylase beta	0.021
Hoxb7	homeo box B7	0.020
Myo1c	myosin IC	0.020
RT1-DOa	RT1 class II, locus DOa	0.020
Tfeb	transcription factor EB	0.020
Tgfbr3	transforming growth factor, beta receptor III	0.020
Clic4	chloride intracellular channel 4	0.020
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.019
Hes5	hairy and enhancer of split 5 (Drosophila)	0.019
Parp9	poly (ADP-ribose) polymerase family, member 9	0.019
Tor1aip2	torsin A interacting protein 2	0.019
Triobp	TRIO and F-actin binding protein	0.019
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.019
Cryge	crystallin, gamma E	0.019
Nxph3	neurexophilin 3	0.019
Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.018
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.018
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.018
Sirpa	signal-regulatory protein alpha	0.018
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.018
Akt2	v-akt murine thymoma viral oncogene homolog 2	0.018
Irgm	immunity-related GTPase family, M	0.017
Map3k3	mitogen activated protein kinase kinase kinase 3	0.017
Gja5	gap junction protein, alpha 5	0.017
Cercam	cerebral endothelial cell adhesion molecule	0.017
Cmklr1	chemokine-like receptor 1	0.017
Igfbp5	insulin-like growth factor binding protein 5	0.017
Lzts2	leucine zipper, putative tumor suppressor 2	0.017
Fgf18	fibroblast growth factor 18	0.017
Plxnb2	plexin B2	0.017
A2m	alpha-2-macroglobulin	0.017
Hdac7	histone deacetylase 7	0.016
Gpr182	G protein-coupled receptor 182	0.016
Flt1	FMS-related tyrosine kinase 1	0.016
Pacs1	phosphofurin acidic cluster sorting protein 1	0.016
Amh	anti-Mullerian hormone	0.016
Foxo1	forkhead box O1	0.016
Egfl7	EGF-like-domain, multiple 7	0.016
Fgf16	fibroblast growth factor 16	0.016
Nfic	nuclear factor I/C	0.016
Clcnkb	chloride channel Kb	0.016
Ptgir	prostaglandin I2 (prostacyclin) receptor (IP)	0.015
Lhx1	LIM homeobox 1	0.015
Mef2d	myocyte enhancer factor 2D	0.015
Cp	ceruloplasmin	0.015
Nmi	N-myc (and STAT) interactor	0.015
Wnt5b	wingless-type MMTV integration site family, member 5B	0.015
Nradd	neurotrophin receptor associated death domain	0.015
Foxe3	forkhead box E3	0.015
Ghrh	growth hormone releasing hormone	0.015
Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.015
Rab34	RAB34, member RAS oncogene family	0.015
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.015
Fat2	FAT tumor suppressor homolog 2 (Drosophila)	0.014
Bcl2	B-cell CLL/lymphoma 2	0.014
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.014
Tbc1d10a	TBC1 domain family, member 10a	0.014
Gdf10	growth differentiation factor 10	0.014
Itgb4	integrin, beta 4	0.014
Tal1	T-cell acute lymphocytic leukemia 1	0.014
Prph2	peripherin 2	0.014
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.014
F10	coagulation factor X	0.014
Tnnt3	troponin T type 3 (skeletal, fast)	0.014
Gulo	gulonolactone (L-) oxidase	0.014
Irf1	interferon regulatory factor 1	0.014
LOC100360587	hypothetical protein LOC100360587	0.013
Slc39a14	solute carrier family 39 (zinc transporter), member 14	0.013
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.013
Timp3	TIMP metallopeptidase inhibitor 3	0.013
Pcsk7	proprotein convertase subtilisin/kexin type 7	0.013
Trim25	tripartite motif-containing 25	0.013
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	0.013
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.013
Arhgap28	Rho GTPase activating protein 28	0.013
Figf	c-fos induced growth factor	0.013
Nab1	Ngfi-A binding protein 1	0.013
Aanat	arylalkylamine N-acetyltransferase	0.013
Casp2	caspase 2	0.013
Kcng1	potassium voltage-gated channel, subfamily G, member 1	0.013
Klk1b3	kallikrein 1-related peptidase b3	0.013
Ccdc8	coiled-coil domain containing 8	0.012
Pdzk1ip1	PDZK1 interacting protein 1	0.012
Ckm	creatine kinase, muscle	0.012
Olr825	olfactory receptor 825	0.012
Tmem101	transmembrane protein 101	0.012
St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.012
Myo10	myosin X	0.012
LOC100360919	Immunoglobulin lambda-like polypeptide 1-like	0.012
Cttn	cortactin	0.012
Atoh8	atonal homolog 8 (Drosophila)	0.012
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.012
Grk4	G protein-coupled receptor kinase 4	0.012
Uggt1	UDP-glucose glycoprotein glucosyltransferase 1	0.012
Nrarp	Notch-regulated ankyrin repeat protein	0.012
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.012
Laptm4a	lysosomal protein transmembrane 4 alpha	0.012
Pim1	pim-1 oncogene	0.012
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.012
Capn1	calpain 1	0.012
Il13ra1	interleukin 13 receptor, alpha 1	0.012
Rrad	Ras-related associated with diabetes	0.012
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.011
Sox17	SRY (sex determining region Y)-box 17	0.011
Myh9	myosin, heavy chain 9, non-muscle	0.011
Stat5b	signal transducer and activator of transcription 5B	0.011	Rat
Arnt	aryl hydrocarbon receptor nuclear translocator	0.011
Rarg	retinoic acid receptor, gamma	0.011
Irf9	interferon regulatory factor 9	0.011
N4bp3	Nedd4 binding protein 3	0.011
Ctf1	cardiotrophin 1	0.011
Hoxd9	homeo box D9	0.011
Cxxc4	CXXC finger 4	0.011
Sorbs3	sorbin and SH3 domain containing 3	0.011
Mmp11	matrix metallopeptidase 11	0.011
Skap1	src kinase associated phosphoprotein 1	0.011
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.011
Il1r1	interleukin 1 receptor, type I	0.011
Lama5	laminin, alpha 5	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
Renbp	renin binding protein	0.011
LOC619574	hypothetical protein LOC619574	0.011
Klf13	Kruppel-like factor 13	0.010
Pim3	pim-3 oncogene	0.010
Krt15	keratin 15	0.010
Gmeb2	glucocorticoid modulatory element binding protein 2	0.010
Tcfe2a	transcription factor E2a	0.010
Testin	testin gene	0.010
Hoxa4	homeo box A4	0.010
Ptpn7	protein tyrosine phosphatase, non-receptor type 7	0.010
Gata6	GATA binding protein 6	0.010
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.010
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.010
Syngr1	synaptogyrin 1	0.010