Rattus norvegicus

0 known processes

Socs6

suppressor of cytokine signaling 6

Socs6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.085
transcription dna templated GO:0006351 377 0.061
rna biosynthetic process GO:0032774 380 0.057
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
regulation of nucleobase containing compound transport GO:0032239 1 0.044
regulation of programmed cell death GO:0043067 341 0.042
regulation of signal transduction GO:0009966 318 0.041
regulation of catalytic activity GO:0050790 304 0.037
cellular component biogenesis GO:0044085 368 0.037
regulation of rna biosynthetic process GO:2001141 381 0.036
ubiquitin dependent protein catabolic process GO:0006511 14 0.035
oxoacid metabolic process GO:0043436 290 0.034
homeostatic process GO:0042592 331 0.034
regulation of rna metabolic process GO:0051252 391 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of cellular localization GO:0060341 263 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
neuron differentiation GO:0030182 368 0.029
programmed cell death GO:0012501 392 0.029
regulation of apoptotic process GO:0042981 335 0.029
positive regulation of rna metabolic process GO:0051254 203 0.028
anterior posterior pattern specification GO:0009952 1 0.028
single organism organelle organization GO:1902589 180 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
regulation of nervous system development GO:0051960 264 0.027
ras protein signal transduction GO:0007265 29 0.027
protein phosphorylation GO:0006468 345 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
rna metabolic process GO:0016070 406 0.026
nucleic acid templated transcription GO:0097659 379 0.026
proteolysis GO:0006508 175 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
protein complex biogenesis GO:0070271 263 0.026
heart morphogenesis GO:0003007 3 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
protein complex assembly GO:0006461 263 0.025
intracellular transport GO:0046907 185 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.024
protein complex subunit organization GO:0071822 302 0.024
cellular lipid metabolic process GO:0044255 208 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.023
positive regulation of transport GO:0051050 245 0.023
organic substance catabolic process GO:1901575 316 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
cell projection organization GO:0030030 302 0.023
regulation of cellular component organization GO:0051128 368 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
regulation of cell development GO:0060284 263 0.022
amine metabolic process GO:0009308 38 0.022
catabolic process GO:0009056 351 0.022
organic acid metabolic process GO:0006082 292 0.022
apoptotic process GO:0006915 381 0.022
neuron projection development GO:0031175 273 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of transforming growth factor beta3 production GO:0032910 2 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of molecular function GO:0044093 230 0.021
cellular component assembly GO:0022607 360 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of protein metabolic process GO:0051246 289 0.021
regulation of molecular function GO:0065009 398 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
cellular amine metabolic process GO:0044106 38 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
cellular ketone metabolic process GO:0042180 51 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
regulation of cell differentiation GO:0045595 320 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
regulation of neurogenesis GO:0050767 247 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
response to growth factor GO:0070848 189 0.018
macromolecular complex assembly GO:0065003 273 0.018
locomotion GO:0040011 237 0.018
chemical homeostasis GO:0048878 292 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of cell death GO:0010942 184 0.018
cellular catabolic process GO:0044248 295 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of transcription dna templated GO:0006355 374 0.017
axis specification GO:0009798 4 0.017
regulation of neuron differentiation GO:0045664 208 0.017
gastrulation GO:0007369 2 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
organophosphate metabolic process GO:0019637 370 0.017
defense response GO:0006952 194 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
oxidation reduction process GO:0055114 304 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of cellular component movement GO:0051270 150 0.016
multi organism reproductive process GO:0044703 262 0.016
response to bacterium GO:0009617 200 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
nucleotide metabolic process GO:0009117 279 0.016
muscle system process GO:0003012 115 0.016
cell migration GO:0016477 197 0.016
regulation of protein modification process GO:0031399 194 0.015
embryonic pattern specification GO:0009880 1 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
negative regulation of signal transduction GO:0009968 83 0.015
response to acid chemical GO:0001101 222 0.015
protein modification by small protein conjugation GO:0032446 31 0.015
localization of cell GO:0051674 202 0.015
response to cytokine GO:0034097 215 0.015
neuron development GO:0048666 286 0.015
positive regulation of signaling GO:0023056 270 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
regulation of cell proliferation GO:0042127 359 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.015
reproductive process GO:0022414 372 0.015
rho protein signal transduction GO:0007266 11 0.015
negative regulation of signaling GO:0023057 157 0.015
protein localization GO:0008104 191 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
muscle structure development GO:0061061 87 0.014
positive regulation of gene expression GO:0010628 244 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
single organism catabolic process GO:0044712 283 0.014
lipid metabolic process GO:0006629 283 0.014
regulation of neuron projection development GO:0010975 161 0.014
cellular component movement GO:0006928 248 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
sterol homeostasis GO:0055092 3 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
protein catabolic process GO:0030163 30 0.014
regulation of phosphorylation GO:0042325 248 0.014
regulation of protein kinase activity GO:0045859 105 0.014
macromolecule localization GO:0033036 252 0.013
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
cellular homeostasis GO:0019725 252 0.013
protein heterooligomerization GO:0051291 89 0.013
negative regulation of cardiac muscle tissue development GO:0055026 3 0.013
purine containing compound metabolic process GO:0072521 253 0.013
cell morphogenesis GO:0000902 142 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
protein modification by small protein conjugation or removal GO:0070647 35 0.013
negative regulation of gene expression GO:0010629 199 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of developmental process GO:0051094 283 0.013
response to biotic stimulus GO:0009607 226 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
regulation of cell projection organization GO:0031344 175 0.013
cellular chemical homeostasis GO:0055082 247 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cation transport GO:0006812 382 0.012
cell motility GO:0048870 202 0.012
cellular response to stress GO:0033554 269 0.012
regulation of catabolic process GO:0009894 113 0.012
mapk cascade GO:0000165 140 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
response to nutrient levels GO:0031667 370 0.012
establishment of protein localization GO:0045184 141 0.012
response to other organism GO:0051707 220 0.012
cholesterol homeostasis GO:0042632 3 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
protein oligomerization GO:0051259 191 0.012
cellular component morphogenesis GO:0032989 155 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cell communication involved in cardiac conduction GO:0086065 2 0.012
response to oxidative stress GO:0006979 186 0.012
response to lipopolysaccharide GO:0032496 191 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
single organism membrane organization GO:0044802 74 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
embryonic axis specification GO:0000578 1 0.011
response to wounding GO:0009611 254 0.011
cellular ion homeostasis GO:0006873 184 0.011
neurological system process GO:0050877 219 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
response to inorganic substance GO:0010035 377 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
ion homeostasis GO:0050801 212 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
heart development GO:0007507 72 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to external biotic stimulus GO:0043207 221 0.011
central nervous system development GO:0007417 311 0.011
eye morphogenesis GO:0048592 4 0.011
biological adhesion GO:0022610 110 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
rhythmic process GO:0048511 156 0.011
negative regulation of transport GO:0051051 136 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
circulatory system development GO:0072359 134 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
regulation of homeostatic process GO:0032844 101 0.010
action potential GO:0001508 54 0.010
nitrogen compound transport GO:0071705 229 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
regulation of locomotion GO:0040012 148 0.010
mesoderm development GO:0007498 2 0.010
muscle cell proliferation GO:0033002 84 0.010
organelle organization GO:0006996 266 0.010
single organism cellular localization GO:1902580 102 0.010

Socs6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010