IMP

Process View

Rattus norvegicus

3 genes annotated in rat

Multi-species View

cholesterol homeostasis

GO:0042632

Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cholesterol homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
Dbp	D site of albumin promoter (albumin D-box) binding protein	0.582
Trib1	tribbles homolog 1 (Drosophila)	0.123
Sardh	sarcosine dehydrogenase	0.098
Nr1d2	nuclear receptor subfamily 1, group D, member 2	0.095
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.091
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.066
Abcg8	ATP-binding cassette, subfamily G (WHITE), member 8	0.063
Ppara	peroxisome proliferator activated receptor alpha	0.060
Apoa5	apolipoprotein A-V	0.060
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.058
Cldn3	claudin 3	0.054
A1cf	APOBEC1 complementation factor	0.049
Hnf1b	HNF1 homeobox B	0.045
Hal	histidine ammonia lyase	0.045
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.043
Hrg	histidine-rich glycoprotein	0.042
Xpnpep2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.042
Cfd	complement factor D (adipsin)	0.040
Acot12	acyl-CoA thioesterase 12	0.039
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.035
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.033
Glyat	glycine-N-acyltransferase	0.032
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.032
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.031
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.030	Fly
Gchfr	GTP cyclohydrolase I feedback regulator	0.030
Mgat2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.030
Tcf3	transcription factor 3	0.030
Unc5cl	unc-5 homolog C (C. elegans)-like	0.029
Ahr	aryl hydrocarbon receptor	0.028
Lama3	laminin, alpha 3	0.028
Tmem82	transmembrane protein 82	0.028
Rxra	retinoid X receptor alpha	0.027
G6pc	glucose-6-phosphatase, catalytic subunit	0.027
Hfe2	hemochromatosis type 2 (juvenile) homolog (human)	0.026
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.026
Lonp2	lon peptidase 2, peroxisomal	0.026
Clcn2	chloride channel 2	0.026
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.026
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.025
A1bg	alpha-1-B glycoprotein	0.024
Smad6	SMAD family member 6	0.024
Rbp7	retinol binding protein 7, cellular	0.024
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.023
Serpinc1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.023
Sec24d	SEC24 family, member D (S. cerevisiae)	0.023
Ntn1	netrin 1	0.023
Slc13a3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.023
Masp2	mannan-binding lectin serine peptidase 2	0.023
Bet1	blocked early in transport 1 homolog (S. cerevisiae)	0.023
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.022
Cd36	CD36 molecule (thrombospondin receptor)	0.022
Gpr182	G protein-coupled receptor 182	0.022
Foxa3	forkhead box A3	0.022
Tmigd1	transmembrane and immunoglobulin domain containing 1	0.021
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.021
Foxa2	forkhead box A2	0.021
Fam96a	family with sequence similarity 96, member A	0.021
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.021
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.021
Asgr1	asialoglycoprotein receptor 1	0.021
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.021
RGD1305347	similar to RIKEN cDNA 2610528J11	0.021
Cps1	carbamoyl-phosphate synthetase 1	0.021
Tyw1	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	0.021
Grb7	growth factor receptor bound protein 7	0.020
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.020
Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.019
Sec23a	Sec23 homolog A (S. cerevisiae)	0.019
Ctsd	cathepsin D	0.019
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.019
Aco1	aconitase 1, soluble	0.019
UST4r	integral membrane transport protein UST4r	0.019
Serpinf2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.019
Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.018
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.018
RGD1306404	similar to mKIAA1402 protein	0.018
Gpr146	G protein-coupled receptor 146	0.018
Vnn1	vanin 1	0.018
Saa4	serum amyloid A4, constitutive	0.018
Keg1	kidney expressed gene 1	0.018
Bmf	Bcl2 modifying factor	0.018
Chuk	conserved helix-loop-helix ubiquitous kinase	0.017
Gprc5c	G protein-coupled receptor, family C, group 5, member C	0.017
F10	coagulation factor X	0.017
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.017
Il1r1	interleukin 1 receptor, type I	0.017
Fbp1	fructose-1,6-bisphosphatase 1	0.017
Cldn7	claudin 7	0.017
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.017
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.017	Rat
Tcf21	transcription factor 21	0.017
F12	coagulation factor XII (Hageman factor)	0.016
RGD1562844	similar to serine (or cysteine) proteinase inhibitor, clade B, member 9	0.016
Cbs	cystathionine beta synthase	0.016
Sdr42e1	short chain dehydrogenase/reductase family 42E, member 1	0.016
Per3	period homolog 3 (Drosophila)	0.016
Mst1	Macrophage stimulating 1 (hepatocyte growth factor-like)	0.016
Ttc7	tetratricopeptide repeat domain 7	0.016
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.016	Fly
F2	coagulation factor II (thrombin)	0.016
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.016
C9	complement component 9	0.016
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.015
Pkp3	plakophilin 3	0.015
Hgf	hepatocyte growth factor	0.015
Irs3	insulin receptor substrate 3	0.015
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.015
Vps52	vacuolar protein sorting 52 homolog (S. cerevisiae)	0.015
Gcgr	glucagon receptor	0.015
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.015
Sts	steroid sulfatase	0.015
Gulo	gulonolactone (L-) oxidase	0.015
Smad3	SMAD family member 3	0.015
Slc28a1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.015
Gfra3	GDNF family receptor alpha 3	0.015
LOC680889	hypothetical protein LOC680889	0.014
Galp	galanin-like peptide	0.014
Irf2bp1	interferon regulatory factor 2 binding protein 1	0.014
Inhbc	inhibin beta C	0.014
Gipc3	GIPC PDZ domain containing family, member 3	0.014
Tmprss2	transmembrane protease, serine 2	0.014
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.014
Cdh17	cadherin 17	0.014
Ihh	Indian hedgehog	0.014
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.014
Fabp1	fatty acid binding protein 1, liver	0.014
Lpl	lipoprotein lipase	0.014
Prpsap1	phosphoribosyl pyrophosphate synthetase-associated protein 1	0.014
Sox13	SRY (sex determining region Y)-box 13	0.014
Apom	apolipoprotein M	0.014
Creb3l3	cAMP responsive element binding protein 3-like 3	0.014
Lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.014
Nrbf2	nuclear receptor binding factor 2	0.014
Agxt	alanine-glyoxylate aminotransferase	0.014
Mocs1	molybdenum cofactor synthesis 1	0.014
Lect2	leukocyte cell-derived chemotaxin 2	0.014
Bhmt2	betaine-homocysteine methyltransferase 2	0.014
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.014
Uox	urate oxidase	0.014
Mcl1	myeloid cell leukemia sequence 1	0.014
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.014
Lrat	lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)	0.014
Fmo1	flavin containing monooxygenase 1	0.014
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.014
LOC686032	hypothetical protein LOC686032	0.013
C8b	complement component 8, beta polypeptide	0.013
Rem1	RAS (RAD and GEM)-like GTP-binding 1	0.013
Ppy	pancreatic polypeptide	0.013
Adap2	ArfGAP with dual PH domains 2	0.013
Fut1	fucosyltransferase 1	0.013
Comp	cartilage oligomeric matrix protein	0.013
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.013
Pcsk9	proprotein convertase subtilisin/kexin type 9	0.013
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.013
Spg20	spastic paraplegia 20 (Troyer syndrome) homolog (human)	0.013
Fgfr4	fibroblast growth factor receptor 4	0.013	Mouse
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.013
Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	0.013
Adra2b	adrenergic, alpha-2B-, receptor	0.013
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.013
LOC687813	similar to Tnf receptor-associated factor 1	0.013
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.013
Runx2	runt-related transcription factor 2	0.013
Ctsf	cathepsin F	0.013
Lrrc26	leucine rich repeat containing 26	0.013
Mttp	microsomal triglyceride transfer protein	0.013
Myo18a	myosin XVIIIa	0.013
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.013
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.013
Akap5	A kinase (PRKA) anchor protein 5	0.012
Slc22a18	solute carrier family 22, member 18	0.012
Rdh2	retinol dehydrogenase 2	0.012
Gif	gastric intrinsic factor	0.012
Muc2	mucin 2, oligomeric mucus/gel-forming	0.012
RGD1309759	similar to cDNA sequence BC013529	0.012
Acsl4	acyl-CoA synthetase long-chain family member 4	0.012
Zbp1	Z-DNA binding protein 1	0.012
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.012
Col13a1	collagen, type XIII, alpha 1	0.012
Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	0.012
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.012
Fbll1	fibrillarin-like 1	0.012
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.012
Neu3	sialidase 3 (membrane sialidase)	0.012
Ddr1	discoidin domain receptor tyrosine kinase 1	0.012
Ccdc61	coiled-coil domain containing 61	0.012
Mc3r	melanocortin 3 receptor	0.012
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.012
Socs6	suppressor of cytokine signaling 6	0.012
Csnk1g2	casein kinase 1, gamma 2	0.012
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.012
Slc12a1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.012
Slc22a23	solute carrier family 22, member 23	0.012
RGD1562291	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)	0.012
Abhd15	abhydrolase domain containing 15	0.012
Mmgt1	membrane magnesium transporter 1	0.012
Etv3	ets variant 3	0.012
Guca2b	guanylate cyclase activator 2B	0.012
Hdac11	histone deacetylase 11	0.012
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.012
Ribc2	RIB43A domain with coiled-coils 2	0.011
Prox1	prospero homeobox 1	0.011
Fgf1	fibroblast growth factor 1	0.011
Dmgdh	dimethylglycine dehydrogenase	0.011
Prss8	protease, serine, 8	0.011
Cblc	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.011
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.011
Ring1	ring finger protein 1	0.011
Slc43a1	solute carrier family 43, member 1	0.011
Rdh5	retinol dehydrogenase 5	0.011
Dbil5	diazepam binding inhibitor-like 5	0.011
Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha	0.011
Hgfac	hepatocyte growth factor activator	0.011
Ly6al	lymphocyte antigen 6 complex, locus A-like	0.011
Snapap	SNAP-associated protein	0.011
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.011
Tbc1d17	TBC1 domain family, member 17	0.011
Cdx1	caudal type homeo box 1	0.011
Dars	aspartyl-tRNA synthetase	0.011
Scd1	stearoyl-Coenzyme A desaturase 1	0.011
Acacb	acetyl-Coenzyme A carboxylase beta	0.011
Herc4	hect domain and RLD 4	0.011
Pip5k1c	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.011
Gstt2	glutathione S-transferase, theta 2	0.011
Pbsn	probasin	0.011
Dpys	dihydropyrimidinase	0.011
Nmur1	neuromedin U receptor 1	0.011
Hpn	hepsin	0.011	Mouse
Pdk2	pyruvate dehydrogenase kinase, isozyme 2	0.011
Sphk2	sphingosine kinase 2	0.011
Abcc3	ATP-binding cassette, subfamily C (CFTR/MRP), member 3	0.011
Aldh9a1	aldehyde dehydrogenase 9 family, member A1	0.011
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.011
Ppp1r15b	protein phosphatase 1, regulatory (inhibitor) subunit 15b	0.011
Nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.011
Rab43	RAB43, member RAS oncogene family	0.011
Fgl1	fibrinogen-like 1	0.011
Ammecr1l	AMME chromosomal region gene 1-like	0.011
Cpb1	carboxypeptidase B1 (tissue)	0.011
Amy2	amylase 2, pancreatic	0.011
Kcnq1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.011
RGD1308722	similar to RIKEN cDNA A130042E20; open reading frame 57	0.011
Agmat	agmatine ureohydrolase (agmatinase)	0.011
Hmha1	histocompatibility (minor) HA-1	0.011
Rorc	RAR-related orphan receptor C	0.011
RGD1305158	similar to RIKEN cDNA 1810030N24	0.011
Nup153	nucleoporin 153	0.011
Mbl1	mannose-binding lectin (protein A) 1	0.010
Serpina4	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	0.010
Kng2	kininogen 2	0.010
Pqcp	polyglutamine-containing protein	0.010
Apoa1	apolipoprotein A-I	0.010
Sirt1	sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)	0.010
Fam53b	family with sequence similarity 53, member B	0.010
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.010
Cln3	ceroid-lipofuscinosis, neuronal 3	0.010
Srebf1	sterol regulatory element binding transcription factor 1	0.010
Colec11	collectin sub-family member 11	0.010
Neu1	sialidase 1 (lysosomal sialidase)	0.010
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.010
Gimap7	GTPase, IMAP family member 7	0.010
Ddc	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.010
Fam3d	family with sequence similarity 3, member D	0.010
Ust5r	integral membrane transport protein UST5r	0.010
Rph3al	rabphilin 3A-like (without C2 domains)	0.010
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.010
Klf13	Kruppel-like factor 13	0.010
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.010
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.010
Rnf139	ring finger protein 139	0.010
Svs6	seminal vesicle secretory protein 6	0.010
Sumf1	sulfatase modifying factor 1	0.010
Apol9a	apolipoprotein L 9a	0.010
Tpra1	transmembrane protein, adipocyte asscociated 1	0.010