Danio rerio

0 known processes

cplx4a

complexin 4a

(Aliases: zgc:153429,CPLX4,si:ch211-233a1.5)

cplx4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 62 0.149
brain development GO:0007420 293 0.111
sensory organ development GO:0007423 393 0.102
visual perception GO:0007601 17 0.099
regulation of signaling GO:0023051 235 0.095
Mouse
signal transduction GO:0007165 455 0.084
cell surface receptor signaling pathway GO:0007166 325 0.082
cilium organization GO:0044782 71 0.075
eye development GO:0001654 277 0.068
cellular response to radiation GO:0071478 4 0.065
regulation of guanylate cyclase activity GO:0031282 6 0.063
maintenance of location GO:0051235 4 0.059
positive regulation of cgmp biosynthetic process GO:0030828 6 0.059
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.053
retina development in camera type eye GO:0060041 146 0.052
regulation of cell communication GO:0010646 232 0.051
Mouse
system process GO:0003008 185 0.051
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.046
smoothened signaling pathway GO:0007224 30 0.046
camera type eye development GO:0043010 222 0.046
stem cell proliferation GO:0072089 4 0.043
apical protein localization GO:0045176 6 0.043
detection of visible light GO:0009584 12 0.042
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.041
sensory perception of light stimulus GO:0050953 19 0.040
cilium morphogenesis GO:0060271 85 0.038
phototransduction GO:0007602 2 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
response to light intensity GO:0009642 1 0.037
negative regulation of signaling GO:0023057 96 0.037
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.037
cellular response to light stimulus GO:0071482 4 0.037
establishment of epithelial cell polarity GO:0090162 2 0.035
digestive tract development GO:0048565 265 0.034
regulation of signal transduction GO:0009966 225 0.033
cell projection morphogenesis GO:0048858 244 0.033
g protein coupled receptor signaling pathway GO:0007186 74 0.033
muscle structure development GO:0061061 196 0.033
regulation of binding GO:0051098 3 0.032
detection of stimulus GO:0051606 29 0.032
sensory perception of chemical stimulus GO:0007606 3 0.032
digestive tract morphogenesis GO:0048546 231 0.032
regulation of axonogenesis GO:0050770 32 0.030
response to light stimulus GO:0009416 46 0.030
polarized epithelial cell differentiation GO:0030859 4 0.030
cell morphogenesis GO:0000902 289 0.030
camera type eye morphogenesis GO:0048593 108 0.030
cilium assembly GO:0042384 58 0.029
sensory perception GO:0007600 39 0.029
regionalization GO:0003002 274 0.028
neuroblast proliferation GO:0007405 2 0.028
regulation of mrna processing GO:0050684 3 0.028
apical junction assembly GO:0043297 1 0.028
regulation of anatomical structure morphogenesis GO:0022603 130 0.028
larval development GO:0002164 2 0.027
localization of cell GO:0051674 244 0.027
cell migration GO:0016477 237 0.027
central nervous system development GO:0007417 387 0.027
cellular component movement GO:0006928 335 0.026
cognition GO:0050890 1 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
ear development GO:0043583 127 0.026
embryonic organ development GO:0048568 381 0.025
phagocytosis GO:0006909 3 0.025
locomotion GO:0040011 313 0.025
regulation of neurotransmitter secretion GO:0046928 1 0.025
Mouse
regulation of collateral sprouting in absence of injury GO:0048696 4 0.025
tube morphogenesis GO:0035239 349 0.024
sensory organ morphogenesis GO:0090596 200 0.024
heart morphogenesis GO:0003007 156 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
regulation of canonical wnt signaling pathway GO:0060828 34 0.024
glucose homeostasis GO:0042593 1 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
regulation of protein binding GO:0043393 3 0.023
negative regulation of cell communication GO:0010648 96 0.023
gastrulation GO:0007369 208 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
positive regulation of transport GO:0051050 2 0.023
carbohydrate homeostasis GO:0033500 1 0.022
wnt signaling pathway GO:0016055 80 0.022
protein complex disassembly GO:0043241 1 0.022
establishment of localization GO:0051234 244 0.022
Mouse
cellular component biogenesis GO:0044085 178 0.022
regulation of cell differentiation GO:0045595 142 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.022
stem cell maintenance GO:0019827 4 0.021
cellular component assembly GO:0022607 170 0.021
aging GO:0007568 2 0.021
regulation of synapse organization GO:0050807 3 0.021
determination of bilateral symmetry GO:0009855 204 0.021
epithelial tube formation GO:0072175 19 0.021
behavior GO:0007610 74 0.021
regulation of neurotransmitter transport GO:0051588 1 0.021
Mouse
digestive system development GO:0055123 289 0.021
synaptic vesicle recycling GO:0036465 1 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.020
eye morphogenesis GO:0048592 144 0.020
negative regulation of signal transduction GO:0009968 94 0.020
medulla oblongata development GO:0021550 4 0.020
cell projection organization GO:0030030 284 0.020
notch signaling pathway GO:0007219 35 0.019
neurotransmitter transport GO:0006836 2 0.019
Mouse
cell motility GO:0048870 244 0.019
head development GO:0060322 303 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of biological quality GO:0065008 263 0.019
Mouse
organelle assembly GO:0070925 110 0.019
exocytosis GO:0006887 1 0.019
sleep GO:0030431 1 0.019
regulation of wnt signaling pathway GO:0030111 53 0.019
regulation of response to stimulus GO:0048583 269 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
hindbrain development GO:0030902 91 0.019
regulation of cgmp biosynthetic process GO:0030826 6 0.019
detection of light stimulus GO:0009583 12 0.018
adherens junction organization GO:0034332 4 0.018
cellular component disassembly GO:0022411 1 0.018
protein targeting to membrane GO:0006612 1 0.018
cellular response to external stimulus GO:0071496 2 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of primary metabolic process GO:0080090 311 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
cyclic nucleotide biosynthetic process GO:0009190 18 0.018
single organism localization GO:1902578 225 0.018
Mouse
nucleocytoplasmic transport GO:0006913 4 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
single organism organelle organization GO:1902589 199 0.017
regulation of hormone secretion GO:0046883 2 0.017
response to monosaccharide GO:0034284 3 0.017
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
autophagy GO:0006914 4 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.017
rna localization GO:0006403 4 0.017
sequestering of metal ion GO:0051238 3 0.017
neuromuscular process controlling balance GO:0050885 3 0.017
golgi vesicle transport GO:0048193 3 0.017
post embryonic organ development GO:0048569 4 0.016
ameboidal type cell migration GO:0001667 143 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
macromolecular complex disassembly GO:0032984 1 0.016
endosome organization GO:0007032 2 0.016
response to abiotic stimulus GO:0009628 122 0.016
protein polymerization GO:0051258 4 0.016
protein depolymerization GO:0051261 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
positive regulation of synapse assembly GO:0051965 1 0.016
lateral inhibition GO:0046331 1 0.016
monoamine transport GO:0015844 1 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
nephron development GO:0072006 31 0.016
regulation of muscle contraction GO:0006937 3 0.015
neuron development GO:0048666 262 0.015
actin filament polymerization GO:0030041 2 0.015
photoreceptor cell outer segment organization GO:0035845 9 0.015
glomerulus development GO:0032835 27 0.015
cell part morphogenesis GO:0032990 246 0.015
multicellular organism growth GO:0035264 4 0.015
positive regulation of guanylate cyclase activity GO:0031284 6 0.015
regulation of cell activation GO:0050865 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
response to chemical GO:0042221 320 0.015
swim bladder development GO:0048794 19 0.015
small molecule catabolic process GO:0044282 3 0.015
circadian sleep wake cycle process GO:0022410 2 0.015
phototransduction visible light GO:0007603 2 0.015
developmental growth GO:0048589 166 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
synaptic vesicle localization GO:0097479 1 0.014
regulation of receptor recycling GO:0001919 3 0.014
response to external stimulus GO:0009605 264 0.014
rhodopsin mediated signaling pathway GO:0016056 1 0.014
regulation of neurological system process GO:0031644 2 0.014
positive regulation of secretion GO:0051047 1 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
positive regulation of epithelial cell differentiation GO:0030858 2 0.014
regulation of localization GO:0032879 104 0.014
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.014
protein acetylation GO:0006473 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
light absorption GO:0016037 2 0.014
collateral sprouting in absence of injury GO:0048669 4 0.014
circadian sleep wake cycle GO:0042745 2 0.014
determination of left right symmetry GO:0007368 179 0.014
cellular response to starvation GO:0009267 1 0.014
regulation of cgmp metabolic process GO:0030823 6 0.014
regulation of developmental process GO:0050793 247 0.014
protein localization to plasma membrane GO:0072659 1 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
cell substrate adherens junction assembly GO:0007045 1 0.014
internal protein amino acid acetylation GO:0006475 2 0.013
gene expression GO:0010467 252 0.013
gtp catabolic process GO:0006184 2 0.013
organelle organization GO:0006996 227 0.013
meiotic cell cycle process GO:1903046 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
heart development GO:0007507 313 0.013
amine metabolic process GO:0009308 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
growth GO:0040007 174 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
cell projection assembly GO:0030031 64 0.013
ribonucleotide biosynthetic process GO:0009260 20 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of gene expression GO:0010468 265 0.013
synaptic vesicle transport GO:0048489 1 0.013
regulation of metabolic process GO:0019222 359 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
response to drug GO:0042493 3 0.013
regulation of cytokine production GO:0001817 3 0.013
establishment or maintenance of cell polarity GO:0007163 29 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
membrane invagination GO:0010324 1 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
regulation of sodium ion transport GO:0002028 2 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of protein polymerization GO:0032271 2 0.012
tight junction assembly GO:0070830 1 0.012
b cell activation GO:0042113 2 0.012
detection of abiotic stimulus GO:0009582 24 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
regulation of chemotaxis GO:0050920 18 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
steroid hormone secretion GO:0035929 1 0.012
nuclear transport GO:0051169 4 0.012
response to uv GO:0009411 3 0.012
endosomal transport GO:0016197 2 0.012
protein acylation GO:0043543 3 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
retina layer formation GO:0010842 24 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
response to glucose GO:0009749 3 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
regulation of cell motility GO:2000145 46 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
regulation of protein complex assembly GO:0043254 3 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
positive regulation of cell cycle GO:0045787 3 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
response to vitamin GO:0033273 3 0.012
cell matrix adhesion GO:0007160 4 0.012
septum transversum development GO:0003343 4 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
entrainment of circadian clock by photoperiod GO:0043153 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
embryonic heart tube development GO:0035050 133 0.012
forebrain cell migration GO:0021885 1 0.012
protein import into nucleus GO:0006606 3 0.012
heterocycle metabolic process GO:0046483 290 0.012
protein heterooligomerization GO:0051291 1 0.012
response to nutrient GO:0007584 3 0.012
meiotic chromosome segregation GO:0045132 3 0.012
regulation of synapse assembly GO:0051963 3 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
angiogenesis GO:0001525 158 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
centrosome localization GO:0051642 1 0.011
vasculature development GO:0001944 278 0.011
protein metabolic process GO:0019538 183 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
secondary metabolic process GO:0019748 3 0.011
cellular response to organic substance GO:0071310 105 0.011
response to hexose GO:0009746 3 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
regulation of cell projection assembly GO:0060491 4 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
single organism membrane fusion GO:0044801 2 0.011
chemosensory behavior GO:0007635 1 0.011
neuron differentiation GO:0030182 353 0.011
pronephros development GO:0048793 69 0.011
ribose phosphate biosynthetic process GO:0046390 20 0.011
nucleic acid transport GO:0050657 2 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
glomerular filtration GO:0003094 6 0.011
generation of neurons GO:0048699 385 0.011
cellular ketone metabolic process GO:0042180 11 0.011
hormone secretion GO:0046879 2 0.011
regulation of cell development GO:0060284 100 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
locomotor rhythm GO:0045475 3 0.011
cellular protein complex disassembly GO:0043624 1 0.011
lipid storage GO:0019915 1 0.011
smooth muscle contraction GO:0006939 2 0.011
cell death GO:0008219 121 0.011
optokinetic behavior GO:0007634 9 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of cell shape GO:0008360 1 0.011
nonmotile primary cilium assembly GO:0035058 2 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
somitogenesis GO:0001756 87 0.011
response to carbohydrate GO:0009743 3 0.010
cellular biosynthetic process GO:0044249 286 0.010
neural nucleus development GO:0048857 15 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
regulation of tube size GO:0035150 2 0.010
negative regulation of biological process GO:0048519 304 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
translational initiation GO:0006413 3 0.010
cell substrate adhesion GO:0031589 4 0.010
somite development GO:0061053 96 0.010
type b pancreatic cell development GO:0003323 4 0.010
adherens junction assembly GO:0034333 1 0.010
renal filtration GO:0097205 10 0.010
regulation of circadian rhythm GO:0042752 4 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
negative regulation of wnt signaling pathway GO:0030178 30 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
cytoplasm organization GO:0007028 4 0.010
inner ear development GO:0048839 126 0.010
macroautophagy GO:0016236 1 0.010
small molecule metabolic process GO:0044281 77 0.010
circadian regulation of gene expression GO:0032922 8 0.010
response to radiation GO:0009314 51 0.010

cplx4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.030
eye disease DOID:5614 0 0.030
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
retinal disease DOID:5679 0 0.021
musculoskeletal system disease DOID:17 0 0.014
retinal degeneration DOID:8466 0 0.013
cardiovascular system disease DOID:1287 0 0.013
retinitis pigmentosa DOID:10584 0 0.011