Danio rerio

25 known processes

igf2a

insulin-like growth factor 2a

(Aliases: igf2,wu:fc26e03,igf2b,IGF-II,zgc:91781,MGC91781)

igf2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
gene expression GO:0010467 252 0.716
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.632
Mouse
negative regulation of biological process GO:0048519 304 0.613
Zebrafish
biosynthetic process GO:0009058 294 0.582
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.551
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.506
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.479
Mouse
rna biosynthetic process GO:0032774 181 0.444
Mouse
regulation of signaling GO:0023051 235 0.425
Human Mouse
response to external stimulus GO:0009605 264 0.397
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.396
Mouse
regionalization GO:0003002 274 0.390
regulation of biosynthetic process GO:0009889 250 0.389
Mouse
head development GO:0060322 303 0.387
Zebrafish
stem cell maintenance GO:0019827 4 0.375
organic cyclic compound biosynthetic process GO:1901362 223 0.373
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.355
Mouse
regulation of metabolic process GO:0019222 359 0.354
Human Mouse
response to monosaccharide GO:0034284 3 0.326
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.313
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.311
Mouse
response to decreased oxygen levels GO:0036293 25 0.308
negative regulation of developmental process GO:0051093 65 0.307
digestive tract morphogenesis GO:0048546 231 0.303
regulation of gene expression GO:0010468 265 0.302
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.294
Mouse
generation of neurons GO:0048699 385 0.294
digestive system development GO:0055123 289 0.284
Mouse
transcription dna templated GO:0006351 181 0.282
Mouse
heterocycle metabolic process GO:0046483 290 0.281
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.279
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.275
Mouse
brain development GO:0007420 293 0.275
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.275
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.273
Mouse
aging GO:0007568 2 0.259
forebrain development GO:0030900 96 0.253
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.251
Mouse
nucleic acid templated transcription GO:0097659 181 0.249
Mouse
regulation of cellular metabolic process GO:0031323 320 0.248
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.244
Mouse
negative regulation of response to stimulus GO:0048585 104 0.242
Zebrafish
response to drug GO:0042493 3 0.239
regulation of transcription dna templated GO:0006355 213 0.230
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.228
organic substance biosynthetic process GO:1901576 289 0.226
Mouse
embryonic organ morphogenesis GO:0048562 274 0.223
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.222
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.220
Human Mouse
small molecule metabolic process GO:0044281 77 0.214
nitrogen compound metabolic process GO:0006807 319 0.213
Mouse
nucleic acid metabolic process GO:0090304 244 0.211
Mouse
transport GO:0006810 220 0.202
ameboidal type cell migration GO:0001667 143 0.197
response to carbohydrate GO:0009743 3 0.194
Zebrafish
response to nutrient GO:0007584 3 0.191
digestive tract development GO:0048565 265 0.191
response to glucocorticoid GO:0051384 1 0.189
regulation of autophagy GO:0010506 3 0.187
rna metabolic process GO:0016070 219 0.186
Mouse
heterocycle biosynthetic process GO:0018130 215 0.181
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.180
establishment of localization GO:0051234 244 0.176
response to corticosteroid GO:0031960 1 0.175
single organism localization GO:1902578 225 0.166
tube morphogenesis GO:0035239 349 0.164
multi organism process GO:0051704 134 0.163
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.161
larval development GO:0002164 2 0.159
transcription from rna polymerase ii promoter GO:0006366 80 0.156
Mouse
response to hormone GO:0009725 48 0.152
Human Mouse
single organism metabolic process GO:0044710 217 0.149
Human Mouse
response to oxygen levels GO:0070482 25 0.148
cognition GO:0050890 1 0.148
heart development GO:0007507 313 0.146
response to stress GO:0006950 263 0.144
Zebrafish
protein metabolic process GO:0019538 183 0.143
Mouse
cellular biosynthetic process GO:0044249 286 0.139
Mouse
response to hexose GO:0009746 3 0.138
Zebrafish
single organism transport GO:0044765 206 0.138
signal transduction GO:0007165 455 0.138
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.133
Mouse
axon development GO:0061564 166 0.132
periodic partitioning GO:0007365 1 0.131
positive regulation of protein kinase b signaling GO:0051897 1 0.130
Human
circadian sleep wake cycle sleep GO:0050802 1 0.130
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.128
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.127
response to abiotic stimulus GO:0009628 122 0.126
positive regulation of metabolic process GO:0009893 108 0.126
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.125
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.124
regulation of response to stimulus GO:0048583 269 0.119
Human Zebrafish Mouse
central nervous system development GO:0007417 387 0.118
Zebrafish
inner ear development GO:0048839 126 0.118
negative regulation of feeding behavior GO:2000252 2 0.116
Zebrafish
skeletal system development GO:0001501 181 0.114
lipid storage GO:0019915 1 0.114
embryonic organ development GO:0048568 381 0.113
regulation of cell cycle GO:0051726 52 0.112
Human
death GO:0016265 121 0.112
maintenance of location GO:0051235 4 0.111
germ line stem cell maintenance GO:0030718 2 0.111
regulation of signal transduction GO:0009966 225 0.111
Human Mouse
gland development GO:0048732 143 0.110
cellular response to lipopolysaccharide GO:0071222 3 0.110
vasculature development GO:0001944 278 0.106
intracellular signal transduction GO:0035556 85 0.105
Human
cell part morphogenesis GO:0032990 246 0.105
neuron development GO:0048666 262 0.104
positive regulation of cell activation GO:0050867 1 0.102
Human
regulation of cell communication GO:0010646 232 0.102
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.102
Mouse
regulation of rna metabolic process GO:0051252 224 0.101
Mouse
response to organic cyclic compound GO:0014070 51 0.099
regulation of proteolysis GO:0030162 24 0.098
single organism biosynthetic process GO:0044711 71 0.094
Mouse
autophagy GO:0006914 4 0.094
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.094
Mouse
cellular ketone metabolic process GO:0042180 11 0.093
cellular response to nutrient levels GO:0031669 2 0.092
erk1 and erk2 cascade GO:0070371 4 0.091
regulation of cellular amine metabolic process GO:0033238 0 0.090
developmental growth GO:0048589 166 0.090
Zebrafish
regulation of dna replication GO:0006275 3 0.090
axonogenesis GO:0007409 152 0.089
phosphate containing compound metabolic process GO:0006796 108 0.088
Human Mouse
sensory organ morphogenesis GO:0090596 200 0.088
regulation of epithelial cell proliferation GO:0050678 3 0.088
skeletal system morphogenesis GO:0048705 102 0.088
multicellular organism growth GO:0035264 4 0.087
cellular response to starvation GO:0009267 1 0.086
response to lipid GO:0033993 60 0.085
cellular response to external stimulus GO:0071496 2 0.084
response to glucose GO:0009749 3 0.084
Zebrafish
pigmentation GO:0043473 85 0.083
positive regulation of biological process GO:0048518 253 0.083
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.081
Human
negative regulation of cellular process GO:0048523 283 0.081
regulation of cell differentiation GO:0045595 142 0.081
neuron differentiation GO:0030182 353 0.079
response to steroid hormone GO:0048545 35 0.078
cellular component movement GO:0006928 335 0.077
positive regulation of cellular metabolic process GO:0031325 94 0.076
Human Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.076
response to alkaloid GO:0043279 2 0.075
cellular response to endogenous stimulus GO:0071495 68 0.074
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.074
Mouse
cell projection organization GO:0030030 284 0.074
positive regulation of cellular process GO:0048522 201 0.074
Human Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.073
Mouse
wound healing GO:0042060 90 0.073
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.073
protein targeting to nucleus GO:0044744 3 0.073
regulation of response to nutrient levels GO:0032107 1 0.072
regulation of multicellular organism growth GO:0040014 4 0.072
protein localization to nucleus GO:0034504 3 0.072
cellular lipid metabolic process GO:0044255 36 0.071
response to biotic stimulus GO:0009607 97 0.070
response to other organism GO:0051707 97 0.069
negative regulation of cell differentiation GO:0045596 46 0.068
cellular component morphogenesis GO:0032989 336 0.068
organic acid metabolic process GO:0006082 31 0.068
regulation of establishment of protein localization GO:0070201 4 0.068
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.067
single organism nuclear import GO:1902593 3 0.067
gamete generation GO:0007276 33 0.067
Zebrafish
negative regulation of cell communication GO:0010648 96 0.066
cellular protein modification process GO:0006464 100 0.066
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.066
amine metabolic process GO:0009308 2 0.065
response to hypoxia GO:0001666 25 0.065
chordate embryonic development GO:0043009 271 0.065
cell migration GO:0016477 237 0.065
regulation of growth GO:0040008 42 0.064
macromolecule biosynthetic process GO:0009059 227 0.064
Mouse
negative regulation of signal transduction GO:0009968 94 0.063
regulation of biological quality GO:0065008 263 0.063
cellular response to extracellular stimulus GO:0031668 2 0.063
response to wounding GO:0009611 116 0.062
Zebrafish
response to organic substance GO:0010033 153 0.062
Human Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 333 0.062
determination of heart left right asymmetry GO:0061371 117 0.062
urogenital system development GO:0001655 97 0.061
Zebrafish
leukocyte proliferation GO:0070661 1 0.060
Human
bmp signaling pathway GO:0030509 52 0.060
cellular amine metabolic process GO:0044106 2 0.059
response to nutrient levels GO:0031667 10 0.059
Zebrafish
stem cell development GO:0048864 82 0.059
stem cell proliferation GO:0072089 4 0.059
neuroblast proliferation GO:0007405 2 0.058
segment polarity determination GO:0007367 1 0.058
oxoacid metabolic process GO:0043436 31 0.058
positive regulation of epithelial cell proliferation GO:0050679 1 0.057
organic substance transport GO:0071702 58 0.057
blood vessel development GO:0001568 246 0.056
positive regulation of stress activated mapk cascade GO:0032874 3 0.056
glial cell migration GO:0008347 3 0.055
cell proliferation GO:0008283 80 0.055
Human
response to bacterium GO:0009617 58 0.054
negative regulation of muscle tissue development GO:1901862 2 0.054
peptide transport GO:0015833 1 0.054
response to estradiol GO:0032355 6 0.054
chemosensory behavior GO:0007635 1 0.053
regulation of nucleotide catabolic process GO:0030811 2 0.053
multicellular organismal metabolic process GO:0044236 2 0.053
regulation of developmental process GO:0050793 247 0.052
locomotion GO:0040011 313 0.052
cell projection morphogenesis GO:0048858 244 0.052
alpha amino acid metabolic process GO:1901605 3 0.052
cell morphogenesis involved in differentiation GO:0000904 195 0.052
cell morphogenesis GO:0000902 289 0.052
developmental pigmentation GO:0048066 48 0.052
reactive oxygen species metabolic process GO:0072593 6 0.051
regulation of inflammatory response GO:0050727 2 0.051
developmental growth involved in morphogenesis GO:0060560 86 0.051
pancreas development GO:0031016 84 0.050
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.049
blood vessel morphogenesis GO:0048514 216 0.049
regulation of erk1 and erk2 cascade GO:0070372 4 0.049
regulation of intracellular protein transport GO:0033157 3 0.049
embryonic heart tube development GO:0035050 133 0.049
stem cell differentiation GO:0048863 117 0.049
glial cell differentiation GO:0010001 42 0.048
regulation of cell proliferation GO:0042127 37 0.048
Human
segmentation GO:0035282 97 0.048
glucose homeostasis GO:0042593 1 0.048
negative regulation of striated muscle tissue development GO:0045843 2 0.048
exocrine system development GO:0035272 28 0.047
Mouse
negative regulation of protein transport GO:0051224 3 0.047
nucleocytoplasmic transport GO:0006913 4 0.047
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.047
circadian sleep wake cycle GO:0042745 2 0.046
cellular carbohydrate metabolic process GO:0044262 4 0.046
Mouse
lipid metabolic process GO:0006629 52 0.046
axon guidance GO:0007411 86 0.046
extrinsic apoptotic signaling pathway GO:0097191 3 0.046
neuron projection development GO:0031175 180 0.046
convergent extension involved in gastrulation GO:0060027 71 0.046
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.045
single organismal cell cell adhesion GO:0016337 29 0.044
positive regulation of neuron death GO:1901216 1 0.044
oocyte maturation GO:0001556 4 0.044
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.044
embryonic skeletal system morphogenesis GO:0048704 93 0.044
neuron projection morphogenesis GO:0048812 161 0.043
regulation of peptidase activity GO:0052547 23 0.043
circadian sleep wake cycle process GO:0022410 2 0.043
regulation of endothelial cell proliferation GO:0001936 1 0.043
cell growth GO:0016049 57 0.043
macromolecule localization GO:0033036 54 0.043
notochord development GO:0030903 54 0.042
ear development GO:0043583 127 0.042
response to oxygen containing compound GO:1901700 55 0.042
Human Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.042
hormone biosynthetic process GO:0042446 3 0.042
heart morphogenesis GO:0003007 156 0.042
sensory system development GO:0048880 76 0.042
regulation of protein transport GO:0051223 3 0.041
regulation of cellular protein metabolic process GO:0032268 52 0.041
Mouse
macromolecule modification GO:0043412 111 0.041
Mouse
regulation of response to extracellular stimulus GO:0032104 1 0.041
regulation of protein targeting GO:1903533 2 0.041
hepaticobiliary system development GO:0061008 98 0.040
growth GO:0040007 174 0.040
Zebrafish
protein secretion GO:0009306 1 0.040
cellular response to hormone stimulus GO:0032870 39 0.040
Human Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.039
Human Mouse
cellular response to oxygen levels GO:0071453 1 0.039
nuclear transport GO:0051169 4 0.039
positive regulation of cell communication GO:0010647 56 0.039
Human Mouse
nuclear import GO:0051170 3 0.039
positive regulation of nucleic acid templated transcription GO:1903508 57 0.039
Mouse
cellular amide metabolic process GO:0043603 4 0.038
establishment of localization in cell GO:0051649 77 0.038
positive regulation of biosynthetic process GO:0009891 68 0.038
Mouse
heart looping GO:0001947 94 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
regulation of cytokine production GO:0001817 3 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.038
regulation of hydrolase activity GO:0051336 28 0.038
negative chemotaxis GO:0050919 1 0.038
angiogenesis GO:0001525 158 0.038
mitochondrion organization GO:0007005 4 0.038
defense response GO:0006952 47 0.038
determination of bilateral symmetry GO:0009855 204 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
Human Mouse
somite development GO:0061053 96 0.037
regulation of circadian rhythm GO:0042752 4 0.037
positive regulation of gene expression GO:0010628 71 0.037
Mouse
cartilage condensation GO:0001502 3 0.036
multicellular organism reproduction GO:0032504 35 0.036
Zebrafish
regulation of cytoplasmic transport GO:1903649 4 0.036
positive regulation of jnk cascade GO:0046330 3 0.036
positive regulation of transport GO:0051050 2 0.036
apoptotic process GO:0006915 116 0.036
hormone transport GO:0009914 2 0.036
determination of left right symmetry GO:0007368 179 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.035
response to external biotic stimulus GO:0043207 97 0.035
carbohydrate biosynthetic process GO:0016051 1 0.035
Mouse
intracellular receptor signaling pathway GO:0030522 30 0.035
regulation of protein kinase b signaling GO:0051896 8 0.035
Human
regulation of protein catabolic process GO:0042176 1 0.035
regulation of catalytic activity GO:0050790 55 0.035
Mouse
retina homeostasis GO:0001895 12 0.035
positive regulation of lipid metabolic process GO:0045834 1 0.035
localization of cell GO:0051674 244 0.035
polarized epithelial cell differentiation GO:0030859 4 0.034
regulation of protein import into nucleus GO:0042306 2 0.034
cell migration involved in gastrulation GO:0042074 79 0.034
phosphorus metabolic process GO:0006793 109 0.034
Human Mouse
eye photoreceptor cell differentiation GO:0001754 45 0.034
regulation of cell death GO:0010941 103 0.034
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.034
negative regulation of metabolic process GO:0009892 86 0.034
eye morphogenesis GO:0048592 144 0.034
i kappab kinase nf kappab signaling GO:0007249 4 0.033
regulation of cysteine type endopeptidase activity GO:2000116 21 0.033
zymogen activation GO:0031638 3 0.033
negative regulation of signaling GO:0023057 96 0.033
neurological system process GO:0050877 62 0.033
protein import GO:0017038 3 0.033
epiboly GO:0090504 41 0.033
regulation of developmental growth GO:0048638 38 0.033
cellular component assembly GO:0022607 170 0.033
response to chemical GO:0042221 320 0.032
Human Zebrafish Mouse
response to extracellular stimulus GO:0009991 10 0.032
Zebrafish
regulation of localization GO:0032879 104 0.032
regulation of circadian sleep wake cycle GO:0042749 1 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.032
specification of symmetry GO:0009799 204 0.032
collagen metabolic process GO:0032963 2 0.032
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
defense response to other organism GO:0098542 33 0.032
germ line stem cell division GO:0042078 1 0.032
peptidyl serine phosphorylation GO:0018105 1 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
negative regulation of axonogenesis GO:0050771 7 0.031
convergent extension GO:0060026 118 0.031
response to acid chemical GO:0001101 17 0.031
regulation of nervous system development GO:0051960 90 0.031
stem cell division GO:0017145 1 0.031
regulation of apoptotic process GO:0042981 98 0.031
cellular response to organic substance GO:0071310 105 0.031
Human Mouse
behavior GO:0007610 74 0.031
Zebrafish
cartilage development GO:0051216 96 0.031
positive regulation of epithelial cell migration GO:0010634 2 0.030
regulation of reproductive process GO:2000241 4 0.030
sensory organ development GO:0007423 393 0.030
neural crest cell development GO:0014032 62 0.030
trabecula morphogenesis GO:0061383 2 0.030
embryonic cranial skeleton morphogenesis GO:0048701 90 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
gtp catabolic process GO:0006184 2 0.030
protein kinase b signaling GO:0043491 9 0.030
Human
cell fate commitment GO:0045165 99 0.030
peripheral nervous system development GO:0007422 55 0.030
negative regulation of growth GO:0045926 10 0.030
inner ear morphogenesis GO:0042472 63 0.029
signal transduction in absence of ligand GO:0038034 1 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
eye photoreceptor cell development GO:0042462 30 0.029
single organism organelle organization GO:1902589 199 0.029
Human
dorsal ventral pattern formation GO:0009953 125 0.029
mesenchyme development GO:0060485 127 0.029
ear morphogenesis GO:0042471 64 0.029
reactive oxygen species biosynthetic process GO:1903409 1 0.029
response to fatty acid GO:0070542 5 0.028
mononuclear cell proliferation GO:0032943 1 0.028
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
response to endogenous stimulus GO:0009719 83 0.028
Human Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.028
negative regulation of chemotaxis GO:0050922 4 0.028
cell adhesion GO:0007155 40 0.028
negative regulation of epithelial cell proliferation GO:0050680 1 0.028
carbohydrate homeostasis GO:0033500 1 0.028
connective tissue development GO:0061448 99 0.028
negative regulation of intracellular signal transduction GO:1902532 22 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
activation of immune response GO:0002253 9 0.027
regulation of axon extension GO:0030516 24 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.027
defense response to bacterium GO:0042742 22 0.027
axis elongation involved in somitogenesis GO:0090245 2 0.027
programmed cell death GO:0012501 119 0.027
system process GO:0003008 185 0.027
cellular response to molecule of bacterial origin GO:0071219 3 0.027
response to vitamin GO:0033273 3 0.027
cell motility GO:0048870 244 0.027
telencephalon development GO:0021537 14 0.027
response to estrogen GO:0043627 27 0.027
positive regulation of macromolecule metabolic process GO:0010604 93 0.027
Mouse
insulin like growth factor receptor signaling pathway GO:0048009 4 0.026
embryonic viscerocranium morphogenesis GO:0048703 52 0.026
positive regulation of endothelial cell proliferation GO:0001938 1 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.026
adult behavior GO:0030534 2 0.026
biological adhesion GO:0022610 40 0.026
keratinocyte differentiation GO:0030216 0 0.026
negative regulation of behavior GO:0048521 6 0.026
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.026
regulation of endopeptidase activity GO:0052548 23 0.026
multi organism reproductive process GO:0044703 36 0.026
Zebrafish
single organism reproductive process GO:0044702 40 0.026
Zebrafish
positive regulation of molecular function GO:0044093 33 0.026
Mouse
negative regulation of neurogenesis GO:0050768 20 0.025
epithelial to mesenchymal transition GO:0001837 21 0.025
negative regulation of cellular biosynthetic process GO:0031327 55 0.025
negative regulation of wnt signaling pathway GO:0030178 30 0.025
anterior posterior pattern specification GO:0009952 152 0.025
protein import into nucleus GO:0006606 3 0.025
liver development GO:0001889 96 0.025
chondrocyte development GO:0002063 4 0.025
protein phosphorylation GO:0006468 47 0.025
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.025
regulation of blood vessel size GO:0050880 2 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
positive regulation of dna metabolic process GO:0051054 1 0.025
somitogenesis GO:0001756 87 0.025
regulation of neuron differentiation GO:0045664 56 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
neuronal action potential GO:0019228 18 0.025
negative regulation of cell development GO:0010721 26 0.025
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.024
renal system development GO:0072001 94 0.024
Zebrafish
lymphocyte proliferation GO:0046651 1 0.024
Human
internal peptidyl lysine acetylation GO:0018393 2 0.024
regulation of stem cell proliferation GO:0072091 2 0.024
negative regulation of cell growth GO:0030308 7 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
growth plate cartilage development GO:0003417 2 0.024
response to uv GO:0009411 3 0.024
notch signaling pathway GO:0007219 35 0.024
phagocytosis GO:0006909 3 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
cellular response to stress GO:0033554 62 0.024
protein localization GO:0008104 40 0.023
cell cell adhesion involved in gastrulation GO:0070586 4 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of dendrite development GO:0050773 3 0.023
gliogenesis GO:0042063 45 0.023
organophosphate metabolic process GO:0019637 37 0.023
extracellular structure organization GO:0043062 27 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
endochondral bone growth GO:0003416 2 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
Mouse
desmosome assembly GO:0002159 2 0.023
embryonic limb morphogenesis GO:0030326 2 0.023
exocrine pancreas development GO:0031017 28 0.023
Mouse
regulation of lipid transport GO:0032368 4 0.023
response to nicotine GO:0035094 2 0.023
negative regulation of nucleic acid templated transcription GO:1903507 45 0.023
cellular response to radiation GO:0071478 4 0.023
astrocyte differentiation GO:0048708 1 0.022
cellular response to prostaglandin stimulus GO:0071379 3 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
cellular protein metabolic process GO:0044267 129 0.022
Mouse
epithelial cell morphogenesis GO:0003382 2 0.022
innate immune response GO:0045087 13 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
Mouse
circadian rhythm GO:0007623 19 0.022
negative regulation of neuron projection development GO:0010977 9 0.022
regulation of cell activation GO:0050865 1 0.022
Human
skeletal muscle organ development GO:0060538 78 0.022
regulation of neurogenesis GO:0050767 87 0.022
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.021
Mouse
peptidyl tyrosine modification GO:0018212 5 0.021
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.021
Mouse
antimicrobial humoral response GO:0019730 2 0.021
wnt signaling pathway GO:0016055 80 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
osteoclast differentiation GO:0030316 1 0.021
response to metal ion GO:0010038 34 0.021
pigment granule transport GO:0051904 19 0.021
positive regulation of myeloid cell differentiation GO:0045639 2 0.021
synaptic target recognition GO:0008039 1 0.021
cellular response to biotic stimulus GO:0071216 3 0.020
regulation of carbohydrate biosynthetic process GO:0043255 1 0.020
Mouse
developmental cell growth GO:0048588 52 0.020
regulation of organ growth GO:0046620 3 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
Mouse
fin regeneration GO:0031101 51 0.020
Zebrafish
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.020
positive regulation of signal transduction GO:0009967 56 0.020
Human Mouse
somatic stem cell maintenance GO:0035019 1 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.020
negative regulation of neuron differentiation GO:0045665 10 0.020
desmosome organization GO:0002934 3 0.020

igf2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
disease of cellular proliferation DOID:14566 0 0.025
musculoskeletal system disease DOID:17 0 0.024
cancer DOID:162 0 0.024