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Process View

Danio rerio

10 genes annotated in zebrafish

response to extracellular stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to extracellular stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to extracellular stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
gata5	GATA-binding protein 5	0.287
gpia	glucose phosphate isomerase a	0.135
crh	corticotropin releasing hormone	0.132
ca2	carbonic anhydrase II	0.097
fgf3	fibroblast growth factor 3	0.091
hnf1ba	HNF1 homeobox Ba	0.090
prl	prolactin	0.084
igf1rb	insulin-like growth factor 1b receptor	0.071	Rat Worm
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.069
oxtl	oxytocin-like	0.064
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.061
pou1f1	POU domain, class 1, transcription factor 1	0.059
bmp2b	bone morphogenetic protein 2b	0.058
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.057	Rat
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.055
shha	sonic hedgehog a	0.055
ihha	Indian hedgehog homolog a	0.053
vdra	vitamin D receptor a	0.051
wnt11r	wingless-type MMTV integration site family, member 11, related	0.051
jag2	jagged 2	0.050
cav1	caveolin 1	0.049	Human
ins	preproinsulin	0.048
odc1	ornithine decarboxylase 1	0.045
mt2	metallothionein 2	0.043
rbp4	retinol binding protein 4, plasma	0.041
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.040
glula	glutamate-ammonia ligase (glutamine synthase) a	0.038	Mouse
bmp4	bone morphogenetic protein 4	0.038
tm4sf4	transmembrane 4 L six family member 4	0.038
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.037	Worm
mao	monoamine oxidase	0.037
si:rp71-39b20.7	si:rp71-39b20.7	0.035
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.033
fabp7a	fatty acid binding protein 7, brain, a	0.033	Zebrafish
crabp2a	cellular retinoic acid binding protein 2, a	0.033	Zebrafish
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.033
igf1	insulin-like growth factor 1	0.033
igf2a	insulin-like growth factor 2a	0.032	Zebrafish
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.032
ca8	carbonic anhydrase VIII	0.032
tp53	tumor protein p53	0.032	Human Mouse Worm Fly
tm9sf2	transmembrane 9 superfamily member 2	0.032
flh	floating head	0.032
foxa2	forkhead box A2	0.031	Mouse Worm
drd2a	dopamine receptor D2a	0.031	Worm
ctgf	connective tissue growth factor	0.030
fgfrl1a	fibroblast growth factor receptor-like 1a	0.029
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.029
neurog3	neurogenin 3	0.029
tac1	tachykinin 1	0.027
zgc:56136	zgc:56136	0.027
ghra	growth hormone receptor a	0.026	Rat
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.026
nr1i2	nuclear receptor subfamily 1, group I, member 2	0.026	Fly
cyp19a1a	cytochrome P450, family 19, subfamily A, polypeptide 1a	0.026
dbh	dopamine beta hydroxylase	0.025
otpa	orthopedia homolog a	0.025
gamt	guanidinoacetate N-methyltransferase	0.025
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.025
cahz	carbonic anhydrase	0.024
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.024
itgb1b.1	integrin, beta 1b.1	0.024
ptgs1	prostaglandin-endoperoxide synthase 1	0.024
ghrb	growth hormone receptor b	0.023	Rat
pbx4	pre-B-cell leukemia transcription factor 4	0.023
ctsl1a	cathepsin L, 1 a	0.023	Rat
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.023
anxa13	annexin A13	0.023
igf2b	insulin-like growth factor 2b	0.022	Zebrafish Rat
LOC100006361	galanin-like	0.022
tshb	thyroid stimulating hormone, beta subunit	0.022
xbp1	X-box binding protein 1	0.022
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.022
col1a2	collagen, type I, alpha 2	0.021
ef1a	elongation factor 1-alpha	0.021
ext2	exostoses (multiple) 2	0.021
stxbp2	syntaxin binding protein 2	0.020
si:dkey-228g21.4	si:dkey-228g21.4	0.020
egr2a	early growth response 2a	0.020
igfbp1b	insulin-like growth factor binding protein 1b	0.020
bhlhe40	basic helix-loop-helix family, member e40	0.020
kdm5c	lysine (K)-specific demethylase 5C	0.020
mtp	microsomal triglyceride transfer protein	0.019
bactin1	bactin1	0.018
mc3r	melanocortin 3 receptor	0.018
aldob	aldolase b, fructose-bisphosphate	0.018
ndfip1	Nedd4 family interacting protein 1	0.018
fshb	follicle stimulating hormone, beta polypeptide	0.018
apoeb	apolipoprotein Eb	0.018	Mouse
rag1	recombination activating gene 1	0.018
sst1.1	somatostatin 1, tandem duplicate 1	0.017
ptger4b	prostaglandin E receptor 4 (subtype EP4) b	0.017
notch1a	notch homolog 1a	0.017
pdlim1	PDZ and LIM domain 1 (elfin)	0.016
ptena	phosphatase and tensin homolog A	0.016	Fly
lama5	laminin, alpha 5	0.016
angptl2	angiopoietin-like 2	0.016
lifrb	leukemia inhibitory factor receptor alpha b	0.016
tp53bp2	tumor protein p53 binding protein, 2	0.016
idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.016
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.016	Rat
nkx2.2a	NK2 transcription factor related 2a	0.016
slc39a1	solute carrier family 39 (zinc transporter), member 1	0.016
drd2b	dopamine receptor D2b	0.015	Worm
crabp1b	cellular retinoic acid binding protein 1b	0.015	Zebrafish
esr1	estrogen receptor 1	0.015
rtn1a	reticulon 1a	0.015
ech1	enoyl CoA hydratase 1, peroxisomal	0.015
klf4a	Kruppel-like transcription factor 4a	0.015
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.015
bmp15	bone morphogenetic protein 15	0.015
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.015	Fly
anxa11b	annexin A11b	0.015
nrg2a	neuregulin 2a	0.015
LOC795916	mucolipin-1-like	0.015
hk1	hexokinase 1	0.015	Yeast
mapk1	mitogen-activated protein kinase 1	0.014	Fly
mbnl2	muscleblind-like 2 (Drosophila)	0.014
spry4	sprouty (Drosophila) homolog 4	0.014
wnt4b	wingless-type MMTV integration site family, member 4b	0.014
gng8	guanine nucleotide binding protein (G protein), gamma 8	0.014	Fly
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.014
mapk4	mitogen-activated protein kinase 4	0.014
ptger2a	prostaglandin E receptor 2a (subtype EP2)	0.014
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.014
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.014
pomca	proopiomelanocortin a	0.014
atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.014
cdx4	caudal type homeo box transcription factor 4	0.014
cat	catalase	0.014
nog2	noggin 2	0.014
chrm2a	cholinergic receptor, muscarinic 2a	0.013
id1	inhibitor of DNA binding 1	0.013
col7a1l	collagen type VII alpha 1-like	0.013
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.013
cga	glycoprotein hormones, alpha polypeptide	0.013
ntrk2b	neurotrophic tyrosine kinase, receptor, type 2b	0.013
rab1a	RAB1A, member RAS oncogene family	0.013	Human
slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.013
gsna	gelsolin a	0.013
actn3a	actinin alpha 3a	0.013
zbtb4	zinc finger and BTB domain containing 4	0.013
sepp1a	selenoprotein P, plasma, 1a	0.013
aqp1a.1	aquaporin 1a, tandem duplicate 1	0.012
npc1	Niemann-Pick disease, type C1	0.012
foxe3	forkhead box E3	0.012
st8sia6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	0.012
fabp2	fatty acid binding protein 2, intestinal	0.012	Zebrafish
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.012
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.012	Fly
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.012
grnb	granulin b	0.012
pdlim3a	PDZ and LIM domain 3a	0.012
fabp11a	fatty acid binding protein 11a	0.012	Zebrafish
rgs4	regulator of G-protein signalling 4	0.012
gcga	glucagon a and glucagon a-like	0.012
gclc	glutamate-cysteine ligase, catalytic subunit	0.012
thrab	thyroid hormone receptor alpha b	0.012	Rat
zgc:112425	zgc:112425	0.011
cd63	Cd63 antigen	0.011
hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)	0.011
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.011
epas1b	endothelial PAS domain protein 1b	0.011	Worm
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.011
wu:fb80a07	wu:fb80a07	0.011
cnn2	calponin 2	0.011
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.011
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.011
fgfr3	fibroblast growth factor receptor 3	0.011
kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.011
dcn	decorin	0.011
adipor1a	adiponectin receptor 1a	0.011
acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.011
vmhc	ventricular myosin heavy chain	0.011
zgc:56466	zgc:56466	0.011
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.011
gng2	guanine nucleotide binding protein (G protein), gamma 2	0.011	Fly
ptprb	protein tyrosine phosphatase, receptor type, b	0.011
zgc:110775	zgc:110775	0.011
tnnt2a	troponin T2a, cardiac	0.011
pdx1	pancreatic and duodenal homeobox 1	0.011
junbl	jun B proto-oncogene, like	0.011
actn1	actinin, alpha 1	0.011
snx4	sorting nexin 4	0.010	Yeast
cops3	COP9 constitutive photomorphogenic homolog subunit 3	0.010
anxa1b	annexin A1b	0.010
egr1	early growth response 1	0.010	Rat
wnt10a	wingless-type MMTV integration site family, member 10a	0.010
m17	IL-6 subfamily cytokine M17	0.010
aldocb	aldolase C, fructose-bisphosphate, b	0.010
chmp4b	chromatin modifying protein 4B	0.010
zgc:112986	zgc:112986	0.010
atp6v1c1b	ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1b	0.010
cry2b	cryptochrome 2b	0.010
adra2b	adrenergic, alpha-2B-, receptor	0.010
sox9a	SRY-box containing gene 9a	0.010
k23	k23 gene	0.010
wls	wntless homolog (Drosophila)	0.010
glud1a	glutamate dehydrogenase 1a	0.010
ldha	lactate dehydrogenase A4	0.010	Mouse
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.010	Rat
rhag	Rhesus blood group-associated glycoprotein	0.010