Danio rerio

0 known processes

mpll

myeloproliferative leukemia virus oncogene, like

(Aliases: c-mpl,tpor.b,tpor)

mpll biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hematopoietic or lymphoid organ development GO:0048534 191 0.302
Zebrafish
regulation of cell shape GO:0008360 1 0.236
axonal defasciculation GO:0007414 2 0.189
cellular component morphogenesis GO:0032989 336 0.174
nuclear transport GO:0051169 4 0.170
sensory organ development GO:0007423 393 0.164
regulation of anatomical structure morphogenesis GO:0022603 130 0.162
immune system process GO:0002376 241 0.160
Zebrafish
blood coagulation GO:0007596 12 0.156
phagocytosis GO:0006909 3 0.153
chemotaxis GO:0006935 104 0.152
homeostatic process GO:0042592 142 0.145
Mouse
generation of neurons GO:0048699 385 0.139
larval development GO:0002164 2 0.139
muscle attachment GO:0016203 9 0.119
embryonic organ development GO:0048568 381 0.118
single organism localization GO:1902578 225 0.110
cytokinesis GO:0000910 3 0.109
cellular component movement GO:0006928 335 0.100
striated muscle cell differentiation GO:0051146 129 0.100
neuron development GO:0048666 262 0.098
establishment of protein localization to organelle GO:0072594 4 0.095
cell motility GO:0048870 244 0.094
peptidyl serine phosphorylation GO:0018105 1 0.094
hemopoiesis GO:0030097 183 0.092
Zebrafish
sensory perception of chemical stimulus GO:0007606 3 0.089
neuron projection morphogenesis GO:0048812 161 0.089
positive regulation of transport GO:0051050 2 0.087
transport GO:0006810 220 0.087
protein import into nucleus GO:0006606 3 0.086
erythrocyte differentiation GO:0030218 54 0.086
neuron differentiation GO:0030182 353 0.085
phagocytosis engulfment GO:0006911 1 0.082
axon development GO:0061564 166 0.080
regulation of biological quality GO:0065008 263 0.077
Mouse
axon guidance GO:0007411 86 0.077
protein localization to nucleus GO:0034504 3 0.077
sensory perception of smell GO:0007608 2 0.076
myeloid cell differentiation GO:0030099 86 0.075
regulation of response to stimulus GO:0048583 269 0.073
establishment of localization GO:0051234 244 0.072
erythrocyte homeostasis GO:0034101 55 0.071
single organism transport GO:0044765 206 0.066
swim bladder inflation GO:0048798 5 0.066
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.066
regulation of protein complex assembly GO:0043254 3 0.065
b cell activation GO:0042113 2 0.064
hemostasis GO:0007599 13 0.063
protein targeting to nucleus GO:0044744 3 0.062
muscle structure development GO:0061061 196 0.061
cell part morphogenesis GO:0032990 246 0.060
regulation of locomotion GO:0040012 55 0.058
localization of cell GO:0051674 244 0.057
fin morphogenesis GO:0033334 53 0.056
skeletal muscle organ development GO:0060538 78 0.056
regulation of protein polymerization GO:0032271 2 0.055
ameboidal type cell migration GO:0001667 143 0.055
establishment of localization in cell GO:0051649 77 0.054
appendage morphogenesis GO:0035107 56 0.053
negative regulation of developmental process GO:0051093 65 0.052
cell substrate adhesion GO:0031589 4 0.052
cell migration involved in sprouting angiogenesis GO:0002042 8 0.051
coagulation GO:0050817 13 0.050
multicellular organism growth GO:0035264 4 0.050
negative regulation of cellular process GO:0048523 283 0.049
taxis GO:0042330 109 0.049
response to external stimulus GO:0009605 264 0.048
muscle cell differentiation GO:0042692 139 0.048
wound healing GO:0042060 90 0.047
cellular localization GO:0051641 97 0.047
membrane invagination GO:0010324 1 0.047
protein heterooligomerization GO:0051291 1 0.047
peptide metabolic process GO:0006518 1 0.046
regulation of multicellular organism growth GO:0040014 4 0.044
regulation of establishment of protein localization GO:0070201 4 0.044
glucose import GO:0046323 2 0.044
epithelial cell differentiation GO:0030855 116 0.044
cell migration GO:0016477 237 0.043
protein polymerization GO:0051258 4 0.043
blood vessel endothelial cell migration GO:0043534 18 0.043
tissue remodeling GO:0048771 4 0.043
skeletal muscle tissue development GO:0007519 67 0.042
convergent extension involved in organogenesis GO:0060029 10 0.042
negative regulation of sequestering of calcium ion GO:0051283 4 0.042
digestive tract development GO:0048565 265 0.042
response to chemical GO:0042221 320 0.041
maintenance of location GO:0051235 4 0.041
tissue migration GO:0090130 37 0.041
organelle assembly GO:0070925 110 0.040
antibacterial humoral response GO:0019731 2 0.039
cell morphogenesis GO:0000902 289 0.039
regulation of translational initiation GO:0006446 1 0.039
regulation of cytokine production GO:0001817 3 0.038
Mouse
regulation of intracellular protein transport GO:0033157 3 0.038
cellular amide metabolic process GO:0043603 4 0.038
single organism nuclear import GO:1902593 3 0.036
cell projection morphogenesis GO:0048858 244 0.036
protein import GO:0017038 3 0.036
liver development GO:0001889 96 0.036
regulation of developmental process GO:0050793 247 0.036
regulation of protein localization to nucleus GO:1900180 2 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
positive regulation of immune effector process GO:0002699 3 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.035
somite development GO:0061053 96 0.035
digestive tract morphogenesis GO:0048546 231 0.035
response to monosaccharide GO:0034284 3 0.035
regulation of embryonic development GO:0045995 47 0.035
regionalization GO:0003002 274 0.034
myoblast fusion GO:0007520 10 0.034
vasculature development GO:0001944 278 0.034
axonogenesis GO:0007409 152 0.034
primitive erythrocyte differentiation GO:0060319 5 0.033
cell matrix adhesion GO:0007160 4 0.033
nuclear import GO:0051170 3 0.033
fatty acid transport GO:0015908 1 0.033
locomotion GO:0040011 313 0.033
skeletal system development GO:0001501 181 0.033
myeloid leukocyte migration GO:0097529 12 0.032
regulation of autophagy GO:0010506 3 0.032
toll like receptor signaling pathway GO:0002224 4 0.032
muscle organ development GO:0007517 101 0.032
camera type eye development GO:0043010 222 0.032
regulation of cell activation GO:0050865 1 0.031
epithelium migration GO:0090132 25 0.031
positive regulation of myeloid cell differentiation GO:0045639 2 0.031
positive regulation of cytokine production GO:0001819 2 0.031
myeloid cell homeostasis GO:0002262 56 0.031
monoamine transport GO:0015844 1 0.030
muscle cell development GO:0055001 115 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
heart development GO:0007507 313 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
tube morphogenesis GO:0035239 349 0.029
extracellular matrix assembly GO:0085029 1 0.029
positive regulation of protein complex assembly GO:0031334 2 0.029
muscle tissue development GO:0060537 110 0.029
muscle contraction GO:0006936 18 0.029
regulation of erythrocyte differentiation GO:0045646 2 0.029
protein complex biogenesis GO:0070271 30 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
fin development GO:0033333 77 0.028
response to stress GO:0006950 263 0.028
neuron neuron synaptic transmission GO:0007270 1 0.027
positive regulation of map kinase activity GO:0043406 3 0.027
growth plate cartilage morphogenesis GO:0003422 1 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of cellular component size GO:0032535 30 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.026
protein metabolic process GO:0019538 183 0.026
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.026
regulation of body fluid levels GO:0050878 16 0.025
autophagy GO:0006914 4 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
regulation of cell motility GO:2000145 46 0.025
regulation of protein targeting GO:1903533 2 0.024
regulation of mrna splicing via spliceosome GO:0048024 3 0.024
definitive hemopoiesis GO:0060216 18 0.024
digestive system development GO:0055123 289 0.024
response to glucocorticoid GO:0051384 1 0.024
macromolecule localization GO:0033036 54 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
neuron projection development GO:0031175 180 0.024
regulation of jun kinase activity GO:0043506 3 0.024
positive regulation of secretion GO:0051047 1 0.024
striated muscle cell development GO:0055002 108 0.024
long chain fatty acid transport GO:0015909 1 0.024
striated muscle tissue development GO:0014706 110 0.023
regulation of blood coagulation GO:0030193 1 0.023
developmental growth GO:0048589 166 0.023
response to corticosteroid GO:0031960 1 0.023
translational initiation GO:0006413 3 0.023
protein secretion GO:0009306 1 0.023
homeostasis of number of cells GO:0048872 62 0.022
Mouse
regulation of dna templated transcription in response to stress GO:0043620 0 0.022
regulation of immune system process GO:0002682 34 0.022
peptide transport GO:0015833 1 0.022
swim bladder maturation GO:0048796 5 0.022
myotube differentiation GO:0014902 45 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.022
actin filament polymerization GO:0030041 2 0.022
kupffer s vesicle development GO:0070121 50 0.022
b cell differentiation GO:0030183 1 0.022
regulation of localization GO:0032879 104 0.021
actin cytoskeleton organization GO:0030036 63 0.021
response to carbohydrate GO:0009743 3 0.021
gland development GO:0048732 143 0.021
protein localization GO:0008104 40 0.021
spermatid differentiation GO:0048515 2 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
multi organism process GO:0051704 134 0.021
angiogenesis GO:0001525 158 0.021
cytoskeleton organization GO:0007010 96 0.021
actomyosin structure organization GO:0031032 53 0.020
innate immune response GO:0045087 13 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
ear development GO:0043583 127 0.020
spermatid development GO:0007286 2 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
hepaticobiliary system development GO:0061008 98 0.020
cell chemotaxis GO:0060326 17 0.019
mononuclear cell proliferation GO:0032943 1 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
regulation of reproductive process GO:2000241 4 0.019
aging GO:0007568 2 0.019
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.019
sprouting angiogenesis GO:0002040 53 0.018
leukocyte proliferation GO:0070661 1 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
sequestering of calcium ion GO:0051208 3 0.018
exocytosis GO:0006887 1 0.018
chordate embryonic development GO:0043009 271 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
lens fiber cell development GO:0070307 3 0.018
actin filament based process GO:0030029 64 0.017
immune system development GO:0002520 191 0.017
Zebrafish
t cell activation GO:0042110 6 0.017
activation of mapk activity GO:0000187 3 0.017
behavior GO:0007610 74 0.017
positive regulation of immune response GO:0050778 11 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
cell recognition GO:0008037 19 0.017
inner ear development GO:0048839 126 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.017
rna localization GO:0006403 4 0.016
regulation of cytoskeleton organization GO:0051493 11 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
biological adhesion GO:0022610 40 0.016
neutrophil migration GO:1990266 10 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of synapse organization GO:0050807 3 0.016
determination of left right symmetry GO:0007368 179 0.016
positive regulation of catabolic process GO:0009896 4 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
regulation of mrna processing GO:0050684 3 0.015
protein stabilization GO:0050821 2 0.015
posttranscriptional regulation of gene expression GO:0010608 14 0.015
neuron projection guidance GO:0097485 86 0.015
endothelial cell migration GO:0043542 19 0.015
smooth muscle contraction GO:0006939 2 0.015
organism emergence from protective structure GO:0071684 4 0.015
regulation of actin cytoskeleton organization GO:0032956 8 0.015
interaction with host GO:0051701 4 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
muscle system process GO:0003012 20 0.015
heterocycle biosynthetic process GO:0018130 215 0.014
cellular component assembly GO:0022607 170 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
antimicrobial humoral response GO:0019730 2 0.014
locomotor rhythm GO:0045475 3 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
vesicle mediated transport GO:0016192 22 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
regulation of dna replication GO:0006275 3 0.014
granulocyte chemotaxis GO:0071621 11 0.014
embryonic hemopoiesis GO:0035162 53 0.014
microtubule cytoskeleton organization GO:0000226 33 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
mitotic cytokinesis GO:0000281 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
single organism intracellular transport GO:1902582 25 0.014
leukocyte chemotaxis GO:0030595 12 0.014
spindle assembly GO:0051225 2 0.014
regulation of cell differentiation GO:0045595 142 0.014
regulation of cell morphogenesis GO:0022604 42 0.013
regulation of anatomical structure size GO:0090066 33 0.013
regulation of cell migration GO:0030334 40 0.013
regulation of blood vessel size GO:0050880 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
specification of symmetry GO:0009799 204 0.013
positive regulation of locomotion GO:0040017 14 0.013
embryonic pattern specification GO:0009880 44 0.013
negative regulation of kinase activity GO:0033673 4 0.013
syncytium formation by plasma membrane fusion GO:0000768 12 0.013
carbohydrate homeostasis GO:0033500 1 0.013
intracellular transport GO:0046907 32 0.013
leukocyte activation GO:0045321 12 0.013
negative regulation of protein transport GO:0051224 3 0.013
actin filament organization GO:0007015 15 0.013
regulation of protein transport GO:0051223 3 0.013
sequestering of metal ion GO:0051238 3 0.013
response to biotic stimulus GO:0009607 97 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
macromolecular complex assembly GO:0065003 35 0.013
syncytium formation GO:0006949 12 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.012
negative regulation of signal transduction GO:0009968 94 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
cellular component biogenesis GO:0044085 178 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
gene expression GO:0010467 252 0.012
lymphocyte proliferation GO:0046651 1 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
nuclear export GO:0051168 1 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
endosomal transport GO:0016197 2 0.012
response to hexose GO:0009746 3 0.012
endocrine system development GO:0035270 65 0.012
organic substance catabolic process GO:1901575 28 0.012
actin filament based movement GO:0030048 1 0.012
cell killing GO:0001906 2 0.012
protein complex subunit organization GO:0071822 46 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
anterior posterior pattern specification GO:0009952 152 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
hatching GO:0035188 4 0.012
transcription dna templated GO:0006351 181 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
sensory organ morphogenesis GO:0090596 200 0.012
cytokine production GO:0001816 4 0.011
Mouse
regulation of organelle organization GO:0033043 29 0.011
catecholamine biosynthetic process GO:0042423 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
protein depolymerization GO:0051261 1 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
cell activation GO:0001775 16 0.011
zymogen activation GO:0031638 3 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
eye development GO:0001654 277 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
cell aging GO:0007569 2 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
pectoral fin development GO:0033339 50 0.011
inner ear morphogenesis GO:0042472 63 0.011
response to hydrogen peroxide GO:0042542 3 0.011
response to wounding GO:0009611 116 0.011
centrosome organization GO:0051297 1 0.011
somatic muscle development GO:0007525 4 0.011
cellular response to external stimulus GO:0071496 2 0.011
epithelial cell development GO:0002064 42 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
reproductive process GO:0022414 40 0.011
macromolecule deacylation GO:0098732 3 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
cognition GO:0050890 1 0.011
long chain fatty acid biosynthetic process GO:0042759 1 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
regulation of binding GO:0051098 3 0.010
cellular protein catabolic process GO:0044257 4 0.010
erythrocyte maturation GO:0043249 8 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
leukocyte migration GO:0050900 15 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
wnt signaling pathway GO:0016055 80 0.010
determination of bilateral symmetry GO:0009855 204 0.010
regulation of metal ion transport GO:0010959 4 0.010
innate immune response activating signal transduction GO:0002758 5 0.010
cytoplasm organization GO:0007028 4 0.010
b cell mediated immunity GO:0019724 3 0.010
negative regulation of catabolic process GO:0009895 3 0.010

mpll disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.018
disease of anatomical entity DOID:7 0 0.018
eye disease DOID:5614 0 0.018
disease of metabolism DOID:0014667 0 0.017
immune system disease DOID:2914 0 0.016
hematopoietic system disease DOID:74 0 0.016
inherited metabolic disorder DOID:655 0 0.010