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Danio rerio

16 genes annotated in zebrafish

cell activation

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell activation" (in gray)

Name	Description	Probability	Func Analog Organism
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.352	Mouse
fgf3	fibroblast growth factor 3	0.296
kita	kit receptor a	0.237	Human Mouse
mmp9	matrix metalloproteinase 9	0.218
pdgfaa	platelet-derived growth factor alpha a	0.193	Human
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.159	Mouse
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.154
fzd7a	frizzled homolog 7a	0.147
bmp2b	bone morphogenetic protein 2b	0.147
tp53	tumor protein p53	0.133	Mouse
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.131
lcp1	lymphocyte cytosolic plastin 1	0.129
dlc	deltaC	0.113
wls	wntless homolog (Drosophila)	0.090
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.089
npm1	nucleophosmin 1	0.088
sgk1	serum/glucocorticoid regulated kinase 1	0.086
runx3	runt-related transcription factor 3	0.084
cmyb	transcription factor cmyb	0.080	Human Mouse
coro1a	coronin, actin binding protein, 1A	0.073	Mouse
lmo4a	LIM domain only 4a	0.070
tbx2b	T-box 2b	0.068
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.067	Mouse
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.066
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.065
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.064	Mouse
wnt9b	wingless-type MMTV integration site family, member 9B	0.063
copeb	core promoter element binding protein	0.050
tp63	tumor protein p63	0.050
si:ch211-173o4.2	si:ch211-173o4.2	0.048
eya2	eyes absent homolog 2 (Drosophila)	0.048
rbp4	retinol binding protein 4, plasma	0.047
fn1	fibronectin 1	0.045	Rat
ryk	receptor-like tyrosine kinase	0.044
il7r	interleukin 7 receptor	0.043
tbx1	T-box 1	0.043
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.043
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.042
cdx1b	caudal type homeobox 1 b	0.042
pcdh18b	protocadherin 18b	0.041
chd	chordin	0.041
axin1	axin 1	0.040
npc1	Niemann-Pick disease, type C1	0.039
tgm2b	transglutaminase 2b	0.038
met	met proto-oncogene (hepatocyte growth factor receptor)	0.038
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.037
mt2	metallothionein 2	0.037
capns1b	calpain, small subunit 1 b	0.037
csrp1a	cysteine and glycine-rich protein 1a	0.036	Human
znf703	zinc finger protein 703	0.036
cdh1	cadherin 1, epithelial	0.036
satb2	SATB homeobox 2	0.036
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.035
cdx4	caudal type homeo box transcription factor 4	0.035
fes	feline sarcoma oncogene	0.035
gdf6a	growth differentiation factor 6a	0.035
notch3	notch homolog 3	0.033
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.032
zgc:64051	zgc:64051	0.031
il12bb	interleukin 12B, b	0.031	Mouse
elovl4b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b	0.030
krt18	keratin 18	0.030
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.030
ccnd1	cyclin D1	0.028
hoxd4a	homeo box D4a	0.027
ptch2	patched 2	0.027
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.027
fgf8a	fibroblast growth factor 8 a	0.026
runx2a	runt-related transcription factor 2a	0.025	Mouse
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.025
hoxa13b	homeo box A13b	0.024
alcamb	activated leukocyte cell adhesion molecule b	0.024
kdrl	kinase insert domain receptor like	0.024
hlxb9la	homeo box HB9 like a	0.024
clic2	chloride intracellular channel 2	0.024
si:dkey-27i16.2	si:dkey-27i16.2	0.024
wnt4a	wingless-type MMTV integration site family, member 4a	0.024	Mouse
sult2st1	sulfotransferase family 2, cytosolic sulfotransferase 1	0.024
ripk2	receptor-interacting serine-threonine kinase 2	0.024
wnt9a	wingless-type MMTV integration site family, member 9A	0.024
enc1	ectodermal-neural cortex (with BTB-like domain)	0.024
jag1b	jagged 1b	0.024
srf	serum response factor	0.024	Mouse
si:dkey-8l13.4	si:dkey-8l13.4	0.024	Mouse
otx1b	orthodenticle homolog 1b	0.023
atad5a	ATPase family, AAA domain containing 5a	0.023
anxa11a	annexin A11a	0.023
zgc:195154	zgc:195154	0.022
mapk14a	mitogen-activated protein kinase 14a	0.022
tgfbr2	transforming growth factor, beta receptor II	0.022	Mouse
axin2	axin 2 (conductin, axil)	0.022
pycard	PYD and CARD domain containing	0.021	Human Mouse
hspa5	heat shock protein 5	0.021
ip6k2	inositol hexaphosphate kinase 2	0.021
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.021
ptena	phosphatase and tensin homolog A	0.020
foxi3a	forkhead box I3a	0.020
rpl11	ribosomal protein L11	0.020
mych	myelocytomatosis oncogene homolog	0.020
btk	Bruton agammaglobulinemia tyrosine kinase	0.020
rag1	recombination activating gene 1	0.020	Mouse
zgc:77517	zgc:77517	0.020
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.020
dag1	dystroglycan 1	0.020
il13ra2	interleukin 13 receptor, alpha 2	0.019	Mouse
stxbp2	syntaxin binding protein 2	0.019	Human
myca	myelocytomatosis oncogene a	0.019
mib	mind bomb	0.019
ca8	carbonic anhydrase VIII	0.019
plagl2	pleiomorphic adenoma gene-like 2	0.019
twist1a	twist1a	0.019
capn9	calpain 9	0.019
hbaa1	hemoglobin alpha adult-1	0.018
si:dkey-204f11.66	si:dkey-204f11.66	0.018
fgg	fibrinogen, gamma polypeptide	0.018
igfbp1a	insulin-like growth factor binding protein 1a	0.018
gmnn	geminin, DNA replication inhibitor	0.018
msxb	muscle segment homeobox B	0.018
emx2	empty spiracles homeobox 2	0.018
tlr3	toll-like receptor 3	0.018
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.018
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.017
caspa	caspase a	0.017
nkx2.1a	NK2 homeobox 1a	0.017
foxe3	forkhead box E3	0.017
psen1	presenilin 1	0.017	Mouse
fgfr1b	fibroblast growth factor receptor 1b	0.017
rpl7a	ribosomal protein L7a	0.017
rac2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.017
cldn5b	claudin 5b	0.017
zgc:64115	zgc:64115	0.017
cpa5	carboxypeptidase A5	0.017
shha	sonic hedgehog a	0.017	Mouse
elovl1b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b	0.017
elk4	ELK4, ETS-domain protein	0.017
tal1	T-cell acute lymphocytic leukemia 1	0.017
jup	junction plakoglobin	0.017
lrrc15	leucine rich repeat containing 15	0.017
lgals2a	lectin, galactoside-binding, soluble, 2a	0.017	Mouse
ahctf1	AT hook containing transcription factor 1	0.016
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.016
tlr9	toll-like receptor 9	0.016
spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.016
pfn1	profilin 1	0.016
mtmr8	myotubularin related protein 8	0.016
cp	ceruloplasmin	0.016
socs1	suppressor of cytokine signaling 1	0.016
boc	brother of CDO	0.016
smoc2	secreted modular calcium binding protein 2	0.016
jak1	Janus kinase 1	0.016
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.016	Mouse
mmp13a	matrix metalloproteinase 13a	0.016
mef2cb	myocyte enhancer factor 2cb	0.016	Mouse
her6	hairy-related 6	0.016
egr1	early growth response 1	0.016	Mouse
gsnb	gelsolin b	0.016
cd63	Cd63 antigen	0.015
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.015
igf2b	insulin-like growth factor 2b	0.015	Human
il1b	interleukin 1, beta and interleukin 1, beta	0.015	Human
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.015
vcp	valosin containing protein	0.015
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.015
fzd5	frizzled homolog 5	0.015	Mouse
ahcy	S-adenosylhomocysteine hydrolase	0.015
rhag	Rhesus blood group-associated glycoprotein	0.015
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.015
nap1l1	nucleosome assembly protein 1, like 1	0.015
id3	inhibitor of DNA binding 3	0.015
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.015
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.014	Rat
sdcbp	syndecan binding protein (syntenin)	0.014
gata4	GATA-binding protein 4	0.014
rpl23a	ribosomal protein L23a	0.014
rag2	recombination activating gene 2	0.014	Mouse
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.014
sulf2l	sulfatase 2, like	0.014
gli2a	GLI-Kruppel family member GLI2a	0.014	Mouse
anxa5b	annexin A5b	0.014
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.014
rtn1a	reticulon 1a	0.014
frem3	Fras1 related extracellular matrix 3	0.014
casp3a	caspase 3, apoptosis-related cysteine protease a	0.014	Mouse
flh	floating head	0.013
grna	granulin a	0.013
bcl2l1	bcl2-like 1	0.013
foxp1b	forkhead box P1b	0.013	Mouse
tln1	talin 1	0.013	Human
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.013
si:ch211-9d9.3	si:ch211-9d9.3	0.013
chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.013
epas1b	endothelial PAS domain protein 1b	0.013
junb	jun B proto-oncogene	0.013
notch2	notch homolog 2	0.013	Mouse
znf148	zinc finger protein 148	0.013
pdcd2	programmed cell death 2	0.013
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.013	Mouse
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.013
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.013
sb:cb247	sb:cb247	0.013
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.013
tfe3b	transcription factor binding to IGHM enhancer 3b	0.013
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.013
sid4	secreted immunoglobulin domain 4	0.013
emx3	empty spiracles homeobox 3	0.013
iclp1	invariant chain-like protein 1	0.013
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.013
lhx3	LIM homeobox 3	0.013
ef1a	elongation factor 1-alpha	0.012
k31	k31 gene	0.012
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.012
dusp6	dual specificity phosphatase 6	0.012
stmn4l	stathmin-like 4, like	0.012
angptl2	angiopoietin-like 2	0.012
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012	Mouse
bhmt	betaine-homocysteine methyltransferase	0.012
disp1	dispatched homolog 1 (Drosophila)	0.012
sqstm1	sequestosome 1	0.012
sulf2	sulfatase 2	0.012
eomesb	eomesodermin homolog b	0.012	Human Mouse
crfa31.2	IL-4RA-like protein 2	0.012
fadd	Fas (tnfrsf6)-associated via death domain	0.012
tmem144b	transmembrane protein 144b	0.012
LOC566708	FL cytokine receptor-like	0.012
ncor2	nuclear receptor co-repressor 2	0.012
unc45a	unc-45 homolog A (C. elegans)	0.012
bmp6	bone morphogenetic protein 6	0.012
zff9	zinc finger protein 9	0.012
rarab	retinoic acid receptor, alpha b	0.012	Human
fgfrl1b	fibroblast growth factor receptor-like 1b	0.012
fzd10	frizzled homolog 10	0.011
c8a	complement component 8, alpha polypeptide	0.011
stat1b	signal transducer and activator of transcription 1b	0.011
hpca	hippocalcin	0.011
lft1	lefty1	0.011
LOC553366	hypothetical protein LOC553366	0.011
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.011
tlr2	toll-like receptor 2	0.011
mpll	myeloproliferative leukemia virus oncogene, like	0.011
pglyrp5	peptidoglycan recognition protein 5	0.011
foxn1	forkhead box N1	0.011	Mouse
fzd6	frizzled homolog 6 (Drosophila)	0.011
odc1	ornithine decarboxylase 1	0.011
myf5	myogenic factor 5	0.011
dio2	deiodinase, iodothyronine, type II	0.011
mef2a	myocyte enhancer factor 2a	0.011
tshb	thyroid stimulating hormone, beta subunit	0.011
col11a1a	collagen, type XI, alpha 1a	0.011
pdlim1	PDZ and LIM domain 1 (elfin)	0.011
sdc2	syndecan 2	0.011
eif4a2	eukaryotic translation initiation factor 4A, isoform 2	0.011
kpna4	karyopherin alpha 4 (importin alpha 3)	0.011
ptpra	protein tyrosine phosphatase, receptor type, A	0.011
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.011
pdlim7	PDZ and LIM domain 7	0.011
arrb2b	arrestin, beta 2b	0.011
ncor1	nuclear receptor co-repressor 1	0.011	Mouse
vtnb	vitronectin b	0.011
arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1	0.011
ryr1b	ryanodine receptor 1b (skeletal)	0.011
tagln2	transgelin 2	0.011
tmem184a	transmembrane protein 184a	0.011
hk1	hexokinase 1	0.011
abca12	ATP-binding cassette, sub-family A (ABC1), member 12	0.011
zeb1	zinc finger E-box binding homeobox 1	0.011	Mouse
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.011
wnt8a	wingless-type MMTV integration site family, member 8a	0.011
fzd8a	frizzled homolog 8a	0.011	Mouse
si:dkey-204a24.9	si:dkey-204a24.9	0.010
six4b	sine oculis homeobox homolog 4b	0.010
gpr182	G protein-coupled receptor 182	0.010
ythdf1	YTH domain family, member 1	0.010
LOC100148845	neurogenin-1-like	0.010
rorcb	RAR-related orphan receptor C b	0.010
esrra	estrogen-related receptor alpha	0.010
abcg2a	ATP-binding cassette, sub-family G (WHITE), member 2a	0.010
il6r	interleukin 6 receptor	0.010
egr2b	early growth response 2b	0.010
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.010	Mouse
ctsk	cathepsin K	0.010
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.010
gli2b	GLI-Kruppel family member GLI2b	0.010
foxa3	forkhead box A3	0.010
mpx	myeloid-specific peroxidase	0.010
jam3b	junctional adhesion molecule 3b	0.010
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.010
gstal	glutathione S-transferase, alpha-like	0.010
ptp4a3	protein tyrosine phosphatase type IVA, member 3	0.010
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.010
vegfab	vascular endothelial growth factor Ab	0.010
msh2	mutS homolog 2 (E. coli)	0.010	Mouse
vamp8	vesicle-associated membrane protein 8 (endobrevin)	0.010
nadl1.1	neural adhesion molecule L1.1	0.010
camk2g2	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2	0.010