Danio rerio

5 known processes

slc45a2

solute carrier family 45, member 2

(Aliases: im:7138762,aim1)

slc45a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 85 1.000
Mouse
pigment cell differentiation GO:0050931 38 0.938
developmental pigmentation GO:0048066 48 0.901
Mouse
camera type eye development GO:0043010 222 0.812
cell part morphogenesis GO:0032990 246 0.666
sensory organ development GO:0007423 393 0.582
eye development GO:0001654 277 0.456
notochord cell differentiation GO:0060034 18 0.451
embryonic organ development GO:0048568 381 0.437
melanocyte differentiation GO:0030318 26 0.424
neuroepithelial cell differentiation GO:0060563 26 0.335
regulation of developmental pigmentation GO:0048070 6 0.324
positive regulation of retina development in camera type eye GO:1902868 1 0.321
retinal pigment epithelium development GO:0003406 8 0.312
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.309
larval development GO:0002164 2 0.299
notochord cell vacuolation GO:0060036 7 0.268
notochord development GO:0030903 54 0.238
retina development in camera type eye GO:0060041 146 0.236
neuron differentiation GO:0030182 353 0.230
eye pigmentation GO:0048069 4 0.230
cell differentiation in spinal cord GO:0021515 40 0.225
tissue remodeling GO:0048771 4 0.219
epithelial cell differentiation GO:0030855 116 0.201
chordate embryonic development GO:0043009 271 0.200
aromatic amino acid family metabolic process GO:0009072 1 0.176
catechol containing compound metabolic process GO:0009712 2 0.162
cell morphogenesis GO:0000902 289 0.158
immune system development GO:0002520 191 0.155
regulation of neural retina development GO:0061074 2 0.150
cilium organization GO:0044782 71 0.149
pigment granule organization GO:0048753 4 0.139
semicircular canal development GO:0060872 24 0.134
cell projection morphogenesis GO:0048858 244 0.134
sensory organ morphogenesis GO:0090596 200 0.130
regulation of retina development in camera type eye GO:1902866 2 0.129
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.127
melanin biosynthetic process GO:0042438 1 0.124
pigment metabolic process GO:0042440 12 0.124
hematopoietic or lymphoid organ development GO:0048534 191 0.112
catecholamine metabolic process GO:0006584 2 0.112
cell projection organization GO:0030030 284 0.109
regulation of multicellular organismal process GO:0051239 277 0.107
osteoclast development GO:0036035 1 0.106
heart morphogenesis GO:0003007 156 0.102
melanosome organization GO:0032438 4 0.101
dorsal ventral pattern formation GO:0009953 125 0.099
regulation of metabolic process GO:0019222 359 0.089
ventral spinal cord development GO:0021517 35 0.085
cellular component movement GO:0006928 335 0.084
secondary metabolic process GO:0019748 3 0.083
negative regulation of autophagy GO:0010507 1 0.083
single organism localization GO:1902578 225 0.080
cardiac atrium development GO:0003230 4 0.079
death GO:0016265 121 0.079
eye morphogenesis GO:0048592 144 0.079
notochord cell development GO:0060035 9 0.075
cellular biogenic amine metabolic process GO:0006576 2 0.072
response to external stimulus GO:0009605 264 0.072
immune system process GO:0002376 241 0.071
urogenital system development GO:0001655 97 0.071
phenol containing compound biosynthetic process GO:0046189 4 0.071
tube morphogenesis GO:0035239 349 0.070
maintenance of location GO:0051235 4 0.067
regulation of signaling GO:0023051 235 0.065
ribonucleoside monophosphate catabolic process GO:0009158 4 0.065
xanthophore differentiation GO:0050936 3 0.065
aging GO:0007568 2 0.064
pigment biosynthetic process GO:0046148 9 0.063
cilium assembly GO:0042384 58 0.062
regulation of multicellular organismal development GO:2000026 223 0.062
cilium morphogenesis GO:0060271 85 0.061
tube closure GO:0060606 1 0.061
positive regulation of cell communication GO:0010647 56 0.060
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.060
appendage development GO:0048736 80 0.059
specification of symmetry GO:0009799 204 0.059
melanin metabolic process GO:0006582 2 0.058
homeostatic process GO:0042592 142 0.058
primary neural tube formation GO:0014020 1 0.057
catechol containing compound biosynthetic process GO:0009713 2 0.056
endosomal transport GO:0016197 2 0.056
anterior posterior pattern specification GO:0009952 152 0.055
cell migration GO:0016477 237 0.055
organic cyclic compound metabolic process GO:1901360 301 0.054
actomyosin structure organization GO:0031032 53 0.054
organelle assembly GO:0070925 110 0.053
atrial ventricular junction remodeling GO:0003294 2 0.053
transport GO:0006810 220 0.051
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.051
glucose import GO:0046323 2 0.050
neuron development GO:0048666 262 0.050
vesicle organization GO:0016050 6 0.049
regulation of cell communication GO:0010646 232 0.049
positive regulation of glucose transport GO:0010828 1 0.049
neuron projection morphogenesis GO:0048812 161 0.049
cellular aromatic compound metabolic process GO:0006725 295 0.048
gtp metabolic process GO:0046039 4 0.048
nucleoside monophosphate catabolic process GO:0009125 4 0.048
indole containing compound metabolic process GO:0042430 2 0.046
cellular amine metabolic process GO:0044106 2 0.046
spinal cord development GO:0021510 46 0.046
guanosine containing compound catabolic process GO:1901069 2 0.045
nonmotile primary cilium assembly GO:0035058 2 0.045
cellular component morphogenesis GO:0032989 336 0.045
digestive system development GO:0055123 289 0.045
regulation of cell shape GO:0008360 1 0.044
melanocyte migration GO:0097324 4 0.044
locomotion GO:0040011 313 0.043
liver development GO:0001889 96 0.043
organelle organization GO:0006996 227 0.043
regulation of autophagy GO:0010506 3 0.043
swim bladder development GO:0048794 19 0.042
embryonic heart tube development GO:0035050 133 0.042
negative regulation of cellular catabolic process GO:0031330 3 0.042
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.042
tyrosine metabolic process GO:0006570 1 0.040
autophagy GO:0006914 4 0.039
developmental maturation GO:0021700 34 0.039
signal transduction GO:0007165 455 0.039
hemopoiesis GO:0030097 183 0.039
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.038
tissue regeneration GO:0042246 74 0.038
establishment of synaptic vesicle localization GO:0097480 1 0.038
neuron projection development GO:0031175 180 0.038
organic cyclic compound biosynthetic process GO:1901362 223 0.037
cardiac muscle tissue development GO:0048738 48 0.037
generation of neurons GO:0048699 385 0.036
neuron projection guidance GO:0097485 86 0.036
catecholamine biosynthetic process GO:0042423 2 0.035
vacuole organization GO:0007033 9 0.035
tissue homeostasis GO:0001894 25 0.035
monovalent inorganic cation transport GO:0015672 42 0.035
epithelial cell migration GO:0010631 25 0.034
central nervous system neuron differentiation GO:0021953 74 0.034
cellular component biogenesis GO:0044085 178 0.034
nucleic acid transport GO:0050657 2 0.034
small molecule catabolic process GO:0044282 3 0.034
chemosensory behavior GO:0007635 1 0.033
determination of heart left right asymmetry GO:0061371 117 0.033
ph reduction GO:0045851 1 0.033
response to abiotic stimulus GO:0009628 122 0.033
single organism organelle organization GO:1902589 199 0.032
phenol containing compound metabolic process GO:0018958 5 0.032
multicellular organismal homeostasis GO:0048871 29 0.032
microglia differentiation GO:0014004 1 0.032
tissue migration GO:0090130 37 0.032
mononuclear cell migration GO:0071674 1 0.032
regionalization GO:0003002 274 0.032
alpha amino acid metabolic process GO:1901605 3 0.031
heart looping GO:0001947 94 0.031
osteoclast differentiation GO:0030316 1 0.030
leukocyte proliferation GO:0070661 1 0.030
single organism transport GO:0044765 206 0.030
regulation of response to stimulus GO:0048583 269 0.030
determination of bilateral symmetry GO:0009855 204 0.030
spinal cord motor neuron differentiation GO:0021522 26 0.030
phagosome maturation GO:0090382 1 0.029
axon guidance GO:0007411 86 0.029
hepaticobiliary system development GO:0061008 98 0.029
heart development GO:0007507 313 0.028
electron transport chain GO:0022900 2 0.028
muscle structure development GO:0061061 196 0.028
embryonic organ morphogenesis GO:0048562 274 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
actin mediated cell contraction GO:0070252 1 0.027
maturation of ssu rrna GO:0030490 1 0.027
taxis GO:0042330 109 0.027
mitochondrion organization GO:0007005 4 0.027
localization of cell GO:0051674 244 0.027
digestive tract development GO:0048565 265 0.027
negative regulation of cellular process GO:0048523 283 0.027
organism emergence from protective structure GO:0071684 4 0.027
iridophore differentiation GO:0050935 9 0.026
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
positive regulation of biological process GO:0048518 253 0.025
rna transport GO:0050658 2 0.024
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.024
exocytosis GO:0006887 1 0.024
embryonic heart tube morphogenesis GO:0003143 108 0.024
central nervous system development GO:0007417 387 0.024
secondary metabolite biosynthetic process GO:0044550 1 0.024
central nervous system myelination GO:0022010 2 0.023
cell motility GO:0048870 244 0.023
embryonic hemopoiesis GO:0035162 53 0.023
neuromuscular synaptic transmission GO:0007274 2 0.023
mononuclear cell proliferation GO:0032943 1 0.023
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.023
kidney development GO:0001822 92 0.023
response to wounding GO:0009611 116 0.022
glial cell differentiation GO:0010001 42 0.022
semicircular canal morphogenesis GO:0048752 18 0.022
b cell differentiation GO:0030183 1 0.022
gland development GO:0048732 143 0.022
lymphocyte proliferation GO:0046651 1 0.022
regulation of developmental process GO:0050793 247 0.022
spermatid development GO:0007286 2 0.022
oxidoreduction coenzyme metabolic process GO:0006733 1 0.021
regulation of systemic arterial blood pressure GO:0003073 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
trabecula morphogenesis GO:0061383 2 0.021
dopamine biosynthetic process GO:0042416 2 0.021
heart rudiment development GO:0003313 8 0.021
response to stress GO:0006950 263 0.021
primary amino compound metabolic process GO:1901160 1 0.020
system process GO:0003008 185 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
regulation of signal transduction GO:0009966 225 0.020
insulin like growth factor receptor signaling pathway GO:0048009 4 0.020
notch signaling pathway GO:0007219 35 0.020
vasculature development GO:0001944 278 0.020
regulation of biological quality GO:0065008 263 0.020
regulation of dendrite development GO:0050773 3 0.020
basement membrane assembly GO:0070831 3 0.020
atp catabolic process GO:0006200 4 0.020
tor signaling GO:0031929 7 0.020
single organism metabolic process GO:0044710 217 0.019
pronephros development GO:0048793 69 0.019
intraciliary transport GO:0042073 7 0.019
pole plasm assembly GO:0007315 4 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
regeneration GO:0031099 91 0.019
regulation of neuronal synaptic plasticity GO:0048168 1 0.019
cardiac atrium morphogenesis GO:0003209 2 0.019
positive regulation of protein complex assembly GO:0031334 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
neural tube development GO:0021915 62 0.018
positive regulation of macrophage chemotaxis GO:0010759 1 0.018
single fertilization GO:0007338 3 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
regulation of heart contraction GO:0008016 32 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
myeloid cell development GO:0061515 32 0.018
cell cell junction maintenance GO:0045217 1 0.018
heart contraction GO:0060047 71 0.018
regulation of epidermis development GO:0045682 2 0.018
venous blood vessel development GO:0060841 9 0.018
cellular biosynthetic process GO:0044249 286 0.018
regulation of binding GO:0051098 3 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
lymphangiogenesis GO:0001946 25 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
lipid storage GO:0019915 1 0.017
positive regulation of neural precursor cell proliferation GO:2000179 1 0.017
actin cytoskeleton organization GO:0030036 63 0.017
establishment of monopolar cell polarity GO:0061162 2 0.017
response to chemical GO:0042221 320 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
positive regulation of chromosome organization GO:2001252 1 0.016
striated muscle cell differentiation GO:0051146 129 0.016
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.016
positive regulation of leukocyte mediated immunity GO:0002705 1 0.016
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.016
epithelium migration GO:0090132 25 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
regulation of notch signaling pathway GO:0008593 16 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
neural retina development GO:0003407 49 0.016
regulation of microtubule depolymerization GO:0031114 1 0.016
ear development GO:0043583 127 0.016
intracellular signal transduction GO:0035556 85 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
regulation of myelination GO:0031641 1 0.016
ribosomal small subunit biogenesis GO:0042274 2 0.016
programmed cell death GO:0012501 119 0.016
cellular pigmentation GO:0033059 30 0.016
eye photoreceptor cell differentiation GO:0001754 45 0.015
neuron fate commitment GO:0048663 26 0.015
blood vessel development GO:0001568 246 0.015
determination of left right symmetry GO:0007368 179 0.015
striated muscle tissue development GO:0014706 110 0.015
digestive tract morphogenesis GO:0048546 231 0.015
lamellipodium organization GO:0097581 1 0.015
medulla oblongata development GO:0021550 4 0.015
macrophage chemotaxis GO:0048246 3 0.015
apoptotic process GO:0006915 116 0.015
positive regulation of transport GO:0051050 2 0.015
phagocytosis GO:0006909 3 0.015
anterior lateral line nerve glial cell development GO:0048939 3 0.015
ovulation cycle process GO:0022602 2 0.014
synaptic vesicle transport GO:0048489 1 0.014
protein complex biogenesis GO:0070271 30 0.014
cell cycle GO:0007049 93 0.014
anatomical structure homeostasis GO:0060249 36 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
axon development GO:0061564 166 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.014
synaptic vesicle localization GO:0097479 1 0.014
amine metabolic process GO:0009308 2 0.014
muscle tissue development GO:0060537 110 0.014
fin regeneration GO:0031101 51 0.014
establishment of epithelial cell apical basal polarity GO:0045198 2 0.014
regulation of protein localization to plasma membrane GO:1903076 1 0.014
protein localization GO:0008104 40 0.014
negative regulation of biological process GO:0048519 304 0.014
positive regulation of catabolic process GO:0009896 4 0.014
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
establishment of localization GO:0051234 244 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
actin filament based movement GO:0030048 1 0.014
regulation of tissue remodeling GO:0034103 2 0.013
macromolecule localization GO:0033036 54 0.013
nuclear export GO:0051168 1 0.013
alcohol biosynthetic process GO:0046165 2 0.013
cellular response to external stimulus GO:0071496 2 0.013
organic substance biosynthetic process GO:1901576 289 0.013
protein secretion GO:0009306 1 0.013
cell projection assembly GO:0030031 64 0.013
oligodendrocyte differentiation GO:0048709 23 0.013
regulation of cell activation GO:0050865 1 0.013
cell substrate junction assembly GO:0007044 2 0.013
positive regulation of secretion GO:0051047 1 0.013
positive regulation of jak stat cascade GO:0046427 2 0.013
blood vessel endothelial cell migration GO:0043534 18 0.013
wnt signaling pathway GO:0016055 80 0.013
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
cell cell signaling GO:0007267 52 0.013
b cell activation GO:0042113 2 0.012
hatching GO:0035188 4 0.012
schwann cell differentiation GO:0014037 9 0.012
lytic vacuole organization GO:0080171 1 0.012
establishment of rna localization GO:0051236 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
protein complex subunit organization GO:0071822 46 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
cell death GO:0008219 121 0.012
protein metabolic process GO:0019538 183 0.012
cellular localization GO:0051641 97 0.012
blood circulation GO:0008015 87 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.012
endothelial cell migration GO:0043542 19 0.012
neuroblast proliferation GO:0007405 2 0.012
lamellipodium assembly GO:0030032 1 0.012
serotonin metabolic process GO:0042428 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
positive regulation of histone modification GO:0031058 1 0.012
negative regulation of ras protein signal transduction GO:0046580 1 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.012
myelination of anterior lateral line nerve axons GO:0048914 3 0.012
regulation of tube size GO:0035150 2 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
cellular component assembly GO:0022607 170 0.011
regulation of jak stat cascade GO:0046425 3 0.011
melanocyte apoptotic process GO:1902362 2 0.011
cation transport GO:0006812 81 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of ph GO:0006885 3 0.011
regulation of cell death GO:0010941 103 0.011
rna localization GO:0006403 4 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
left right pattern formation GO:0060972 19 0.011
transition metal ion transport GO:0000041 6 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
detection of abiotic stimulus GO:0009582 24 0.011
camera type eye morphogenesis GO:0048593 108 0.011
macromolecular complex disassembly GO:0032984 1 0.010
developmental programmed cell death GO:0010623 4 0.010
microtubule based movement GO:0007018 33 0.010
spermatid differentiation GO:0048515 2 0.010
regulation of macrophage chemotaxis GO:0010758 1 0.010
stem cell proliferation GO:0072089 4 0.010
mrna export from nucleus GO:0006406 1 0.010
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.010
cellular response to nutrient levels GO:0031669 2 0.010
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
regulation of striated muscle contraction GO:0006942 2 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
hindbrain development GO:0030902 91 0.010
cortical cytoskeleton organization GO:0030865 1 0.010

slc45a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.060
disease of anatomical entity DOID:7 0 0.060
hematopoietic system disease DOID:74 0 0.048
retinal disease DOID:5679 0 0.023
sensory system disease DOID:0050155 0 0.023
nervous system disease DOID:863 0 0.023
eye disease DOID:5614 0 0.023
eye and adnexa disease DOID:1492 0 0.023
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.015
auditory system disease DOID:2742 0 0.010
nonsyndromic deafness DOID:0050563 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010
organ system cancer DOID:0050686 0 0.010