IMP

Process View

Danio rerio

19 genes annotated in zebrafish

swim bladder development

The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "swim bladder development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "swim bladder development" (in gray)

Name	Description	Probability	Func Analog Organism
lrp2	low density lipoprotein-related protein 2	0.398
wnt1	wingless-type MMTV integration site family, member 1	0.389	Zebrafish
wnt4a	wingless-type MMTV integration site family, member 4a	0.389	Zebrafish
dag1	dystroglycan 1	0.386
wnt5b	wingless-type MMTV integration site family, member 5b	0.332	Zebrafish
ptch1	patched 1	0.282
dkk1b	dickkopf 1b	0.259
wnt2	wingless-type MMTV integration site family member 2	0.200
flh	floating head	0.188
fzd7a	frizzled homolog 7a	0.180
wif1	wnt inhibitory factor 1	0.178
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.170
wnt10a	wingless-type MMTV integration site family, member 10a	0.157	Zebrafish
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.153
crb2a	crumbs homolog 2a	0.140	Zebrafish
wnt3	wingless-type MMTV integration site family, member 3	0.125	Zebrafish
wnt10b	wingless-type MMTV integration site family, member 10b	0.120	Zebrafish
crb3a	crumbs homolog 3a	0.112
sox2	SRY-box containing gene 2	0.111
tbx1	T-box 1	0.106
sfrp1a	secreted frizzled-related protein 1a	0.102
map2k4a	mitogen-activated protein kinase kinase 4a	0.089
foxa2	forkhead box A2	0.078
hnf1ba	HNF1 homeobox Ba	0.076
gli1	GLI-Kruppel family member 1	0.075
ift88	intraflagellar transport 88 homolog	0.074
fgf17	fibroblast growth factor 17	0.066
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.064
col11a2	collagen type XI alpha-2	0.062
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.058
lamb1a	laminin, beta 1a	0.057
col2a1a	collagen type II, alpha-1a	0.057
her5	hairy-related 5	0.056
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.056
kif17	kinesin family member 17	0.056
bmp2a	bone morphogenetic protein 2a	0.052
stmn2a	stathmin-like 2a	0.050
spry2	sprouty homolog 2	0.049
ptch2	patched 2	0.048
cdh23	cadherin-like 23	0.048
wnt16	wingless-type MMTV integration site family, member 16	0.046
sim2	single-minded homolog 2 (Drosophila)	0.044
fzd8a	frizzled homolog 8a	0.044	Zebrafish
dctn1a	dynactin 1a	0.043
nadl1.2	neural adhesion molecule L1.2	0.043
slc45a2	solute carrier family 45, member 2	0.042
wnt3a	wingless-type MMTV integration site family, member 3A	0.041	Zebrafish
zbtb4	zinc finger and BTB domain containing 4	0.041
flr	fleer	0.040
rarga	retinoic acid receptor gamma a	0.037
sfrp1b	secreted frizzled-related protein 1b	0.037
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.036
ndr2	nodal-related 2	0.036
foxa1	forkhead box A1	0.034
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.033
dharma	dharma	0.031
fzd5	frizzled homolog 5	0.031
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.031	Zebrafish
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.030
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.029	Zebrafish
fgfr2	fibroblast growth factor receptor 2	0.029
wnt8b	wingless-type MMTV integration site family, member 8b	0.029	Zebrafish
wls	wntless homolog (Drosophila)	0.027
dbh	dopamine beta hydroxylase	0.027
zfyve26	zinc finger, FYVE domain containing 26	0.027
znf503	zinc finger protein 503	0.027
pcdh8	protocadherin 8	0.027
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.027
si:dkey-273o13.1	si:dkey-273o13.1	0.026
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.026
her12	hairy-related 12	0.026
has2	hyaluronan synthase 2	0.025
fech	ferrochelatase	0.025
shhb	sonic hedgehog b	0.025	Zebrafish
LOC100000500	sclerostin-like	0.025
zgc:162420	zgc:162420	0.025
tph1b	tryptophan hydroxylase 1b	0.024
ptn	pleiotrophin	0.024
dbx1a	developing brain homeobox 1a	0.024
runx3	runt-related transcription factor 3	0.023
top3a	topoisomerase (DNA) III alpha	0.023
frzb	frizzled-related protein	0.023	Zebrafish
si:ch211-1n9.7	si:ch211-1n9.7	0.022
zgc:112329	zgc:112329	0.022
tbx6	T-box gene 6	0.022
jag1b	jagged 1b	0.022
fezf2	FEZ family zinc finger 2	0.022
robo3	roundabout homolog 3	0.021
gnl2	guanine nucleotide binding protein-like 2 (nucleolar)	0.021
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.021
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.020
bmp16	bone morphogenetic protein 16	0.020
nkx6.2	NK6 transcription factor related, locus 2	0.020
traf3ip1	TNF receptor-associated factor 3 interacting protein 1	0.020
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.019
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.019
pea3	ETS-domain transcription factor pea3	0.019
gle1	GLE1 RNA export mediator homolog (yeast)	0.019
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.019
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.019
zgc:63629	zgc:63629	0.019
sb:eu385	sb:eu385	0.019
prickle1b	prickle homolog 1 (Drosophila) b	0.019
snap25b	synaptosome-associated protein 25b	0.018
otop1	otopetrin 1	0.018
notch3	notch homolog 3	0.018
vps18	vacuolar protein sorting protein 18	0.018
atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.018
hmx1	H6 homeo box 1	0.018
hhip	hedgehog interacting protein	0.018
nrarpb	notch-regulated ankyrin repeat protein b	0.018
nrarpa	notch-regulated ankyrin repeat protein a	0.017
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.017
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.017
pomca	proopiomelanocortin a	0.017
fgfrl1b	fibroblast growth factor receptor-like 1b	0.017
fn1	fibronectin 1	0.017
map2k4b	mitogen-activated protein kinase kinase 4b	0.017
map2k7	mitogen-activated protein kinase kinase 7	0.017
fzd7b	frizzled homolog 7b	0.017	Zebrafish
glud1a	glutamate dehydrogenase 1a	0.017
zgc:171802	zgc:171802	0.017
eya1	eyes absent homolog 1	0.016
dab1b	disabled homolog 1b (Drosophila)	0.016
mgp	matrix Gla protein	0.016
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.016
cry2b	cryptochrome 2b	0.016
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.016
wnt9a	wingless-type MMTV integration site family, member 9A	0.016	Zebrafish
npnt	nephronectin	0.016
wnt5a	wingless-type MMTV integration site family, member 5a	0.016	Zebrafish
stat1b	signal transducer and activator of transcription 1b	0.015
mc5rb	melanocortin 5b receptor	0.015
gli2a	GLI-Kruppel family member GLI2a	0.015
LOC564872	monocarboxylate transporter 7-like	0.015
vtg3	vitellogenin 3, phosvitinless	0.015
cplx4a	complexin 4a	0.015
lhx6	LIM homeobox 6	0.015
mespb	mesoderm posterior b	0.015
lama5	laminin, alpha 5	0.014
vsx1	visual system homeobox 1 homolog, chx10-like	0.014
pkd2	polycystic kidney disease 2	0.014
ihha	Indian hedgehog homolog a	0.014
ihhb	Indian hedgehog homolog b	0.014	Zebrafish
prdm14	PR domain containing 14	0.014
mib	mind bomb	0.013
nid2a	nidogen 2a (osteonidogen)	0.013
nnr	nanor	0.013
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.013
ntn1b	netrin 1b	0.013
rest	RE1-silencing transcription factor	0.013
prdm1a	PR domain containing 1a, with ZNF domain	0.013
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.013
bmp3	bone morphogenetic protein 3	0.013
klf4	Kruppel-like factor 4	0.013
vps53	vacuolar protein sorting 53 homolog (S. cerevisiae)	0.012
rxrbb	retinoid x receptor, beta b	0.012
pmp22a	peripheral myelin protein 22a	0.012
foxd3	forkhead box D3	0.012
foxd5	forkhead box D5	0.012
grhl2b	grainyhead-like 2b (Drosophila)	0.012
ncoa3	nuclear receptor coactivator 3	0.012
atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.012
gja3	gap junction protein, alpha 3	0.012
p4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2	0.012
mbnl1	muscleblind-like (Drosophila)	0.012
fzd10	frizzled homolog 10	0.012	Zebrafish
elnb	elastin b	0.012
foxj1a	forkhead box J1a	0.012
wu:fc18c07	wu:fc18c07	0.012
esrrgb	estrogen-related receptor gamma b	0.012
hoxc4a	homeo box C4a	0.012
tyr	tyrosinase	0.012
nort	notch-regulated transcript	0.012
znf711	zinc finger protein 711	0.012
eya2	eyes absent homolog 2 (Drosophila)	0.012
spry4	sprouty (Drosophila) homolog 4	0.011
eomesa	eomesodermin homolog a	0.011
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.011	Zebrafish
LOC566708	FL cytokine receptor-like	0.011
angpt1	angiopoietin 1	0.011
glcea	glucuronyl C5-epimerase a	0.011
cables1	Cdk5 and Abl enzyme substrate 1	0.011
dlx4b	distal-less homeobox gene 4b	0.011
ciz1	CDKN1A interacting zinc finger protein 1	0.011
nes	nestin	0.011
fbln1	fibulin 1	0.011
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.011
cd99l2	CD99 antigen-like 2	0.011
slc12a9	solute carrier family 12 (potassium/chloride transporters), member 9	0.011
lbx1a	ladybird homeobox 1a	0.011
zgc:158643	zgc:158643	0.011
arl4ab	ADP-ribosylation factor-like 4ab	0.011
wnt11r	wingless-type MMTV integration site family, member 11, related	0.010	Zebrafish
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.010
crb1	crumbs homolog 1 (Drosophila)	0.010	Zebrafish
uros	uroporphyrinogen III synthase	0.010
im:7162646	im:7162646	0.010
kif3b	kinesin family member 3B	0.010
mapk7	mitogen-activated protein kinase 7	0.010
csad	cysteine sulfinic acid decarboxylase	0.010
grk7a	G-protein-coupled receptor kinase 7a	0.010
spry1	sprouty homolog 1 (Drosophila)	0.010