IMP

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Homo sapiens

1 genes annotated in human

Multi-species View

negative regulation of interleukin 5 secretion

GO:2000663

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-5 secretion.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 5 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of interleukin 5 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
SNAP23	synaptosomal-associated protein, 23kDa	0.974
IFNA10	interferon, alpha 10	0.965	Human
IFNA16	interferon, alpha 16	0.702	Human
IFNA4	interferon, alpha 4	0.612
TAS2R16	taste receptor, type 2, member 16	0.516
IFNA14	interferon, alpha 14	0.348
IFNA17	interferon, alpha 17	0.333
IFNA21	interferon, alpha 21	0.310	Human
IFNA7	interferon, alpha 7	0.275	Human
APP	amyloid beta (A4) precursor protein	0.206
COLEC10	collectin sub-family member 10 (C-type lectin)	0.173
CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	0.173
IFNA13	interferon, alpha 13	0.101
C6orf10	chromosome 6 open reading frame 10	0.098
NMBR	neuromedin B receptor	0.097
IFNA2	interferon, alpha 2	0.086
HTN3	histatin 3	0.084
HTN1	histatin 1	0.081
LECT2	leukocyte cell-derived chemotaxin 2	0.080
OR7A10	olfactory receptor, family 7, subfamily A, member 10	0.080
OR1D2	olfactory receptor, family 1, subfamily D, member 2	0.079
STATH	statherin	0.071
OR2B2	olfactory receptor, family 2, subfamily B, member 2	0.067
IFNA8	interferon, alpha 8	0.066	Human
ANXA10	annexin A10	0.062
SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)	0.055
F13B	coagulation factor XIII, B polypeptide	0.053
GYPB	glycophorin B (MNS blood group)	0.052
ODAM	odontogenic, ameloblast asssociated	0.052
CSN2	casein beta	0.051
HIST1H3J	histone cluster 1, H3j	0.048
CYLC2	cylicin, basic protein of sperm head cytoskeleton 2	0.046
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	0.046
GYPA	glycophorin A (MNS blood group)	0.043
SEMG2	semenogelin II	0.042
CSN1S1	casein alpha s1	0.041
ANP32C	acidic (leucine-rich) nuclear phosphoprotein 32 family, member C	0.041
TAS2R7	taste receptor, type 2, member 7	0.040
TAS2R8	taste receptor, type 2, member 8	0.039
TRIM48	tripartite motif containing 48	0.039
RRH	retinal pigment epithelium-derived rhodopsin homolog	0.039
CTAGE1	cutaneous T-cell lymphoma-associated antigen 1	0.038
SLCO1B1	solute carrier organic anion transporter family, member 1B1	0.037
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.034
MTMR7	myotubularin related protein 7	0.033
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.033
PRG4	proteoglycan 4	0.032
PDC	phosducin	0.032
MORC1	MORC family CW-type zinc finger 1	0.031
OR52A1	olfactory receptor, family 52, subfamily A, member 1	0.030
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.030
IL21	interleukin 21	0.030
AFM	afamin	0.029
PSG11	pregnancy specific beta-1-glycoprotein 11	0.028
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.028
SI	sucrase-isomaltase (alpha-glucosidase)	0.028
OLAH	oleoyl-ACP hydrolase	0.027
TAAR2	trace amine associated receptor 2	0.027
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.026
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.026
TMPRSS11E	transmembrane protease, serine 11E	0.025
ZNF157	zinc finger protein 157	0.025
IAPP	islet amyloid polypeptide	0.025
CSN3	casein kappa	0.025
FSHR	follicle stimulating hormone receptor	0.025
IFNA6	interferon, alpha 6	0.025	Human
IFNB1	interferon, beta 1, fibroblast	0.024	Human
FGL1	fibrinogen-like 1	0.024
DPPA4	developmental pluripotency associated 4	0.024
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.024
FABP2	fatty acid binding protein 2, intestinal	0.023
CLDN17	claudin 17	0.023
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.023
GNRHR	gonadotropin-releasing hormone receptor	0.023
IMPG2	interphotoreceptor matrix proteoglycan 2	0.023
CHRNA6	cholinergic receptor, nicotinic, alpha 6	0.022
GPR22	G protein-coupled receptor 22	0.022
PDE6C	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.022
HNF4G	hepatocyte nuclear factor 4, gamma	0.022
MIA2	melanoma inhibitory activity 2	0.022
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.022
HESX1	HESX homeobox 1	0.021
TSHB	thyroid stimulating hormone, beta	0.021
TM4SF20	transmembrane 4 L six family member 20	0.021
IMPG1	interphotoreceptor matrix proteoglycan 1	0.021
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.021
CDH9	cadherin 9, type 2 (T1-cadherin)	0.020
ZNF81	zinc finger protein 81	0.020
HIST1H4F	histone cluster 1, H4f	0.020
LGSN	lengsin, lens protein with glutamine synthetase domain	0.020
GCG	glucagon	0.020
TMPRSS11B	transmembrane protease, serine 11B	0.020
C10orf68	chromosome 10 open reading frame 68	0.019
CTNNA3	catenin (cadherin-associated protein), alpha 3	0.019
HRH4	histamine receptor H4	0.019
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.019
HAVCR1	hepatitis A virus cellular receptor 1	0.019
SNTG1	syntrophin, gamma 1	0.019
IL2	interleukin 2	0.019
POU1F1	POU class 1 homeobox 1	0.018
PCDH11X	protocadherin 11 X-linked	0.018
EPYC	epiphycan	0.018
IL26	interleukin 26	0.018
OR5P2	olfactory receptor, family 5, subfamily P, member 2	0.018
MSTN	myostatin	0.018
GLRA3	glycine receptor, alpha 3	0.018
ACCN5	amiloride-sensitive cation channel 5, intestinal	0.018
OMG	oligodendrocyte myelin glycoprotein	0.018
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.018
NTS	neurotensin	0.018
TEX12	testis expressed 12	0.017
PPEF2	protein phosphatase, EF-hand calcium binding domain 2	0.017
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.017
UGT1A7	UDP glucuronosyltransferase 1 family, polypeptide A7	0.017
PMP2	peripheral myelin protein 2	0.017
PTTG2	pituitary tumor-transforming 2	0.017
OR1A2	olfactory receptor, family 1, subfamily A, member 2	0.017
TRPC7	transient receptor potential cation channel, subfamily C, member 7	0.017
EDA2R	ectodysplasin A2 receptor	0.017
RNF17	ring finger protein 17	0.017
PTH	parathyroid hormone	0.017
TFDP3	transcription factor Dp family, member 3	0.016
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.016
C1orf129	chromosome 1 open reading frame 129	0.016
TAS2R4	taste receptor, type 2, member 4	0.016
PSG2	pregnancy specific beta-1-glycoprotein 2	0.016
ZNF816	zinc finger protein 816	0.016
KRTAP2-4	keratin associated protein 2-4	0.016
S100G	S100 calcium binding protein G	0.016
CPB1	carboxypeptidase B1 (tissue)	0.015
TRDN	triadin	0.015
FLG	filaggrin	0.015
CD80	CD80 molecule	0.015
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.015
IFNA1	interferon, alpha 1	0.015	Human
CRISP1	cysteine-rich secretory protein 1	0.015
ADAM2	ADAM metallopeptidase domain 2	0.015
SCN11A	sodium channel, voltage-gated, type XI, alpha subunit	0.015
SLC25A31	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31	0.015
ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6	0.015
SEMG1	semenogelin I	0.014
SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.014
SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2	0.014
STXBP5L	syntaxin binding protein 5-like	0.014
SLC25A21	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21	0.014
CST1	cystatin SN	0.014
RNF133	ring finger protein 133	0.014
PCDHGB6	protocadherin gamma subfamily B, 6	0.014
LIPF	lipase, gastric	0.014
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.014
PLAC1	placenta-specific 1	0.014
GPRC6A	G protein-coupled receptor, family C, group 6, member A	0.014
B3GALT1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.014
EDDM3B	epididymal protein 3B	0.014
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	0.014
ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	0.014
ANKRD7	ankyrin repeat domain 7	0.014
AADAC	arylacetamide deacetylase (esterase)	0.014
HYAL4	hyaluronoglucosaminidase 4	0.014
SMCP	sperm mitochondria-associated cysteine-rich protein	0.014
TAAR1	trace amine associated receptor 1	0.014
OR12D3	olfactory receptor, family 12, subfamily D, member 3	0.014
RFPL1	ret finger protein-like 1	0.014
GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.013
SPZ1	spermatogenic leucine zipper 1	0.013
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.013
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.013
ZNF208	zinc finger protein 208	0.013
C1orf105	chromosome 1 open reading frame 105	0.013
MMP27	matrix metallopeptidase 27	0.013
KIF24	kinesin family member 24	0.013
SPIN2A	spindlin family, member 2A	0.013
KRTAP1-1	keratin associated protein 1-1	0.013
GPR85	G protein-coupled receptor 85	0.013
CFHR5	complement factor H-related 5	0.013
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.013
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	0.013
SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10	0.013
IFNE	interferon, epsilon	0.013	Human
CPB2	carboxypeptidase B2 (plasma)	0.013
HIST1H1B	histone cluster 1, H1b	0.013
HIST1H2BL	histone cluster 1, H2bl	0.013
ADAM21	ADAM metallopeptidase domain 21	0.013
LHCGR	luteinizing hormone/choriogonadotropin receptor	0.013
GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.013
KRTAP4-7	keratin associated protein 4-7	0.013
TPTE	transmembrane phosphatase with tensin homology	0.013
ZBBX	zinc finger, B-box domain containing	0.013
ANP32D	acidic (leucine-rich) nuclear phosphoprotein 32 family, member D	0.012
SMR3B	submaxillary gland androgen regulated protein 3B	0.012
OCLM	oculomedin	0.012
CDH10	cadherin 10, type 2 (T2-cadherin)	0.012
CA1	carbonic anhydrase I	0.012
AGTR2	angiotensin II receptor, type 2	0.012
OPHN1	oligophrenin 1	0.012
STARD6	StAR-related lipid transfer (START) domain containing 6	0.012
CD4	CD4 molecule	0.012
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.012
ART3	ADP-ribosyltransferase 3	0.012
PCDHB8	protocadherin beta 8	0.012
ZFHX4	zinc finger homeobox 4	0.012
ARG1	arginase, liver	0.012
TIGD6	tigger transposable element derived 6	0.012
PPEF1	protein phosphatase, EF-hand calcium binding domain 1	0.012
DEFB126	defensin, beta 126	0.012
TMEM212	transmembrane protein 212	0.012
UGT2A2	UDP glucuronosyltransferase 2 family, polypeptide A2	0.012
HIST1H1A	histone cluster 1, H1a	0.011
SPATA16	spermatogenesis associated 16	0.011
C9	complement component 9	0.011
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.011
CNGB3	cyclic nucleotide gated channel beta 3	0.011
ADAM18	ADAM metallopeptidase domain 18	0.011
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.011
AFP	alpha-fetoprotein	0.011
CCR9	chemokine (C-C motif) receptor 9	0.011
CLDN16	claudin 16	0.011
MCF2	MCF.2 cell line derived transforming sequence	0.011
VIP	vasoactive intestinal peptide	0.011
TEX15	testis expressed 15	0.011
SLCO1C1	solute carrier organic anion transporter family, member 1C1	0.011
CRYGB	crystallin, gamma B	0.011
MYF5	myogenic factor 5	0.011
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.011
ASB4	ankyrin repeat and SOCS box containing 4	0.011
PBOV1	prostate and breast cancer overexpressed 1	0.011
GYPE	glycophorin E (MNS blood group)	0.011
SLC26A3	solute carrier family 26, member 3	0.011
PSG3	pregnancy specific beta-1-glycoprotein 3	0.011
C17orf77	chromosome 17 open reading frame 77	0.011
KRTAP9-9	keratin associated protein 9-9	0.011
HIST1H4I	histone cluster 1, H4i	0.011
ANGPTL3	angiopoietin-like 3	0.011
PCDHGA10	protocadherin gamma subfamily A, 10	0.011
CDY1	chromodomain protein, Y-linked, 1	0.011
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.011
SMR3A	submaxillary gland androgen regulated protein 3A	0.011
MC4R	melanocortin 4 receptor	0.011
DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.011
ASCL3	achaete-scute complex homolog 3 (Drosophila)	0.011
OR2B6	olfactory receptor, family 2, subfamily B, member 6	0.010
SPRR2B	small proline-rich protein 2B	0.010
ADAM29	ADAM metallopeptidase domain 29	0.010
LRRC31	leucine rich repeat containing 31	0.010
LRRC19	leucine rich repeat containing 19	0.010
MYOZ2	myozenin 2	0.010
NOX3	NADPH oxidase 3	0.010
PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.010
OR1E1	olfactory receptor, family 1, subfamily E, member 1	0.010
TSGA13	testis specific, 13	0.010
ALX1	ALX homeobox 1	0.010
MTMR8	myotubularin related protein 8	0.010
SPINK1	serine peptidase inhibitor, Kazal type 1	0.010
DAZ4	deleted in azoospermia 4	0.010