IMP
Process View
Homo sapiens
8 genes annotated in human
porphyria
DOID:13268
An inherited metabolic disorder that involves certain enzymes in the heme bio-synthetic pathway resulting in the overproduction and accumulation of the porphyrins.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "porphyria"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| B2M | beta-2-microglobulin | 0.569 | ||
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.549 | ||
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 0.129 | ||
| BCS1L | BCS1-like (S. cerevisiae) | 0.070 | ||
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial | 0.048 | ||
| ATPIF1 | ATPase inhibitory factor 1 | 0.034 | ||
| FOXRED1 | FAD-dependent oxidoreductase domain containing 1 | 0.033 | ||
| BABAM1 | BRISC and BRCA1 A complex member 1 | 0.027 | ||
| HBG2 | hemoglobin, gamma G | 0.022 | ||
| UROD | uroporphyrinogen decarboxylase | 0.021 | ||
| UROS | uroporphyrinogen III synthase | 0.020 | ||
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.016 | ||
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 0.016 | ||
| HBB | hemoglobin, beta | 0.015 | ||
| IFRD2 | interferon-related developmental regulator 2 | 0.015 | ||
| HINT2 | histidine triad nucleotide binding protein 2 | 0.015 | ||
| COMMD4 | COMM domain containing 4 | 0.014 | ||
| METTL1 | methyltransferase like 1 | 0.014 | ||
| MTX1 | metaxin 1 | 0.014 | ||
| COG4 | component of oligomeric golgi complex 4 | 0.014 | ||
| C7orf49 | chromosome 7 open reading frame 49 | 0.014 | ||
| HBA2 | hemoglobin, alpha 2 | 0.013 | ||
| COMMD9 | COMM domain containing 9 | 0.013 | ||
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 0.012 | ||
| TFRC | transferrin receptor (p90, CD71) | 0.012 | ||
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | 0.011 | ||
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 0.011 | ||
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.011 | ||
| ITGB1BP1 | integrin beta 1 binding protein 1 | 0.010 | ||
| PPOX | protoporphyrinogen oxidase | 0.006 | ||
| FECH | ferrochelatase | 0.003 | ||
| ALAS2 | aminolevulinate, delta-, synthase 2 | 0.001 | ||
| HMBS | hydroxymethylbilane synthase | 0.001 | ||
| HFE | hemochromatosis | 0.001 | ||
| CPOX | coproporphyrinogen oxidase | 0.001 |