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10 genes annotated in human

hypothyroidism

DOID:1459

A thyroid gland disease which involves an underproduction of thyroid hormone.

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Known genes in the process in human Include functional analogs

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Name	Description	Probability	Func Analog Organism
TBX5	T-box 5	0.745
NKX2-1	NK2 homeobox 1	0.138	Human
GATA4	GATA binding protein 4	0.055
MED1	mediator complex subunit 1	0.018
NCOA6	nuclear receptor coactivator 6	0.010
DRD2	dopamine receptor D2	0.010
PAX8	paired box 8	0.003
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.002
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.002
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.002
DUOX2	dual oxidase 2	0.002
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.002
TPO	thyroid peroxidase	0.001
DUOXA2	dual oxidase maturation factor 2	0.001
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.001
TSHB	thyroid stimulating hormone, beta	0.001