IMP

Process View

Homo sapiens

1 genes annotated in human

negative regulation of cellular organofluorine metabolic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cellular organofluorine metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cellular organofluorine metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	1.000
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.999	Human
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.946	Human
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.848
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.689	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.678	Human
ADH6	alcohol dehydrogenase 6 (class V)	0.454
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.386
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.336
CFHR4	complement factor H-related 4	0.276
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.269
LAMC3	laminin, gamma 3	0.248
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.233
MAST1	microtubule associated serine/threonine kinase 1	0.229
FETUB	fetuin B	0.203
ALDOB	aldolase B, fructose-bisphosphate	0.186
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.181
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.158
OTC	ornithine carbamoyltransferase	0.145
AGXT2	alanine--glyoxylate aminotransferase 2	0.144
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.122
C6	complement component 6	0.117
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.109
AADAC	arylacetamide deacetylase (esterase)	0.104
GLYAT	glycine-N-acyltransferase	0.096
A1CF	APOBEC1 complementation factor	0.094
C8B	complement component 8, beta polypeptide	0.085
FMO4	flavin containing monooxygenase 4	0.084
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.071
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.065
F11	coagulation factor XI	0.064
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.063	Human
RNF32	ring finger protein 32	0.063
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.060
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.057
GJB1	gap junction protein, beta 1, 32kDa	0.048
A2M	alpha-2-macroglobulin	0.048
MUC3A	mucin 3A, cell surface associated	0.047
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.047
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.043
G6PC	glucose-6-phosphatase, catalytic subunit	0.042
XDH	xanthine dehydrogenase	0.041
HRG	histidine-rich glycoprotein	0.039
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.039
PNLIPRP1	pancreatic lipase-related protein 1	0.038
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.038	Human
MAT1A	methionine adenosyltransferase I, alpha	0.037
GSTA3	glutathione S-transferase alpha 3	0.037
HPX	hemopexin	0.034
RAB3D	RAB3D, member RAS oncogene family	0.033
HAL	histidine ammonia-lyase	0.031
FABP1	fatty acid binding protein 1, liver	0.030
ANXA10	annexin A10	0.029
C4BPA	complement component 4 binding protein, alpha	0.029
C9orf68	chromosome 9 open reading frame 68	0.029
MASP2	mannan-binding lectin serine peptidase 2	0.029
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.027
F9	coagulation factor IX	0.027
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.027
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.026
BHMT	betaine--homocysteine S-methyltransferase	0.025
DNASE1L3	deoxyribonuclease I-like 3	0.024
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.024
ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	0.023
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.022
MEP1B	meprin A, beta	0.022
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.022	Human
FGL1	fibrinogen-like 1	0.022
LRRC31	leucine rich repeat containing 31	0.022
ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.021
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.021
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.021
LPA	lipoprotein, Lp(a)	0.020
ACRV1	acrosomal vesicle protein 1	0.020
F13B	coagulation factor XIII, B polypeptide	0.019
MTTP	microsomal triglyceride transfer protein	0.019
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.019
GYS2	glycogen synthase 2 (liver)	0.019
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.019
ATP10B	ATPase, class V, type 10B	0.019
TMPRSS6	transmembrane protease, serine 6	0.018
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.018
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.018
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.017
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.017
KLK13	kallikrein-related peptidase 13	0.016
HNF4G	hepatocyte nuclear factor 4, gamma	0.016
SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4	0.016
PLG	plasminogen	0.016
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.016
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.015
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.015
SGK2	serum/glucocorticoid regulated kinase 2	0.015
TTPA	tocopherol (alpha) transfer protein	0.015
CRP	C-reactive protein, pentraxin-related	0.015
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.014
PON1	paraoxonase 1	0.014
CES3	carboxylesterase 3	0.013
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.013
PIPOX	pipecolic acid oxidase	0.013
COLEC10	collectin sub-family member 10 (C-type lectin)	0.013
CPB2	carboxypeptidase B2 (plasma)	0.013
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.013
CD4	CD4 molecule	0.013
GPR35	G protein-coupled receptor 35	0.013
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.013
PLA2G1B	phospholipase A2, group IB (pancreas)	0.013
PIGR	polymeric immunoglobulin receptor	0.012
HABP2	hyaluronan binding protein 2	0.012
CNGA1	cyclic nucleotide gated channel alpha 1	0.012
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.012
APOA1	apolipoprotein A-I	0.012
HPD	4-hydroxyphenylpyruvate dioxygenase	0.011
HP	haptoglobin	0.011
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	0.011
PLD2	phospholipase D2	0.011
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	0.011
PAH	phenylalanine hydroxylase	0.011
NTS	neurotensin	0.011
FAM164C	family with sequence similarity 164, member C	0.010
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.010
OR7E24	olfactory receptor, family 7, subfamily E, member 24	0.010
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.010
PZP	pregnancy-zone protein	0.010
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.010
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.010
DPYS	dihydropyrimidinase	0.010
ADRA1A	adrenergic, alpha-1A-, receptor	0.010
LOC55908	hepatocellular carcinoma-associated gene TD26	0.010
AFM	afamin	0.010
C8A	complement component 8, alpha polypeptide	0.010