IMP
Process View
negative regulation of lyase activity
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of lyase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.995 | ||
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.671 | Fly | |
| GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.455 | ||
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.409 | Rat | |
| TBC1D10A | TBC1 domain family, member 10A | 0.379 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.213 | ||
| PDZK1 | PDZ domain containing 1 | 0.210 | Human | |
| BCR | breakpoint cluster region | 0.170 | ||
| ADORA2A | adenosine A2a receptor | 0.148 | ||
| GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.147 | ||
| PTEN | phosphatase and tensin homolog | 0.098 | ||
| EZR | ezrin | 0.093 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.090 | ||
| NSF | N-ethylmaleimide-sensitive factor | 0.082 | ||
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.051 | ||
| SH3GL3 | SH3-domain GRB2-like 3 | 0.030 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.027 | Human | |
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.022 | Human | |
| SLC26A3 | solute carrier family 26, member 3 | 0.015 | ||
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.012 | ||
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 | 0.010 |