IMP

Process View

Homo sapiens

5 genes annotated in human

negative regulation of vitamin d biosynthetic process

Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of vitamin d biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of vitamin d biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.891
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.826	Human
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.814	Human
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.807
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.793	Human
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.578
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.422
JUB	jub, ajuba homolog (Xenopus laevis)	0.190
BCL3	B-cell CLL/lymphoma 3	0.173
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.165	Human
TNIP2	TNFAIP3 interacting protein 2	0.101
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.076
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.067
JAG2	jagged 2	0.025
KDM1A	lysine (K)-specific demethylase 1A	0.022
NELL2	NEL-like 2 (chicken)	0.021
EGR1	early growth response 1	0.017
NOTCH1	notch 1	0.013
USHBP1	Usher syndrome 1C binding protein 1	0.012
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.011