IMP

Process View

4 genes annotated in human

actin filament severing

The process in which an actin filament is broken down into smaller filaments.

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Known genes in the process in human Include functional analogs

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Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "actin filament severing" (in gray)

Name	Description	Probability	Func Analog Organism
ACTB	actin, beta	0.974
ACTG1	actin, gamma 1	0.670
CFL1	cofilin 1 (non-muscle)	0.047	Yeast
TSPO	translocator protein (18kDa)	0.045
CFL2	cofilin 2 (muscle)	0.043	Yeast
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.041
PFN1	profilin 1	0.039
LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	0.037
GAS7	growth arrest-specific 7	0.029
ARRB1	arrestin, beta 1	0.022
COTL1	coactosin-like 1 (Dictyostelium)	0.019
DSTN	destrin (actin depolymerizing factor)	0.017	Yeast
LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	0.014
ARRB2	arrestin, beta 2	0.014
ARHGAP4	Rho GTPase activating protein 4	0.013	Human
ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.013
TEX11	testis expressed 11	0.012
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.012
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.011
FXYD5	FXYD domain containing ion transport regulator 5	0.011
FMNL1	formin-like 1	0.011	Mouse
MVP	major vault protein	0.011
TOM1L1	target of myb1 (chicken)-like 1	0.010
CORO1A	coronin, actin binding protein, 1A	0.010
VCL	vinculin	0.010
ACTA1	actin, alpha 1, skeletal muscle	0.010