|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
1.000
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
1.000
|
Human Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.999
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
11 |
0.999
|
|
|
|
stabilization of membrane potential
|
GO:0030322 |
1 |
0.999
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.999
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.999
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.998
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.997
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.995
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.995
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.995
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.995
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.995
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.994
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.993
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.993
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.992
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.992
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.990
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.989
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.988
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.985
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.985
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.984
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.984
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.983
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.983
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.982
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.979
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.979
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.977
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.973
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.973
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.969
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.969
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.968
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.968
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.968
|
|
|
|
sensory perception of sweet taste
|
GO:0050916 |
2 |
0.967
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.967
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.966
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.966
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.964
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.964
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.963
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.962
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.961
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.960
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.958
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.957
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.954
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.953
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.953
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.948
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.947
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.947
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.947
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.947
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
10 |
0.945
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.945
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.944
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.944
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.943
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.940
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.939
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.939
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.938
|
Mouse |
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
10 |
0.936
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.934
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.934
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.934
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.933
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.933
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.932
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.932
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
13 |
0.931
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.928
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.928
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.926
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.925
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.924
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.920
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.919
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.919
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.912
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.912
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.911
|
|
|
|
adenylate cyclase activating adrenergic receptor signaling pathway
|
GO:0071880 |
3 |
0.903
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.902
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.900
|
|
|
|
regulation of rhodopsin mediated signaling pathway
|
GO:0022400 |
1 |
0.897
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.896
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.896
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.894
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.894
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.892
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.891
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.890
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.887
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.887
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.885
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.884
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.883
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.881
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.880
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.878
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.876
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.875
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.875
|
|
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
1 |
0.874
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.872
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.870
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.867
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.864
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.861
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.855
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.855
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.853
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.852
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.851
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.851
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.850
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.845
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.845
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.844
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.844
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.844
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.842
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.837
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.836
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.836
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.836
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.832
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.831
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.831
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.831
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.830
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.821
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.818
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.813
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.813
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.811
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.810
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.810
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.809
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.802
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.801
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.800
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.797
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.796
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.795
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.794
|
Human Mouse |
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.792
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.787
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.787
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.785
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.779
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.779
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.778
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.778
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.772
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.759
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.754
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.754
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.748
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.744
|
|
|
|
growth
|
GO:0040007 |
202 |
0.744
|
Worm |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.738
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.732
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.731
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.729
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.727
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.724
|
Human |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.724
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.721
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.718
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.714
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.709
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.704
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
18 |
0.703
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.700
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.697
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.697
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.695
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.695
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.695
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
9 |
0.690
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.690
|
|
|
|
phototransduction visible light
|
GO:0007603 |
2 |
0.685
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.683
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.679
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.679
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.675
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.673
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.673
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.672
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.669
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.668
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.666
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.665
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.663
|
Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.657
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.656
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.651
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.651
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.649
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.649
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.646
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.642
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.642
|
|
|
|
response to parathyroid hormone
|
GO:0071107 |
3 |
0.639
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.638
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.635
|
Human |
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.634
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.633
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.629
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.627
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.627
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.625
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.622
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.622
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.622
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.618
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.615
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.614
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.613
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.613
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.612
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.611
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.605
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.603
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.601
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.594
|
|
|
|
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure
|
GO:0001999 |
1 |
0.590
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.589
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.588
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.578
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.575
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.572
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.569
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.564
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.563
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.562
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.562
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.560
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.557
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.556
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.556
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.551
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.548
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.545
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.543
|
|
|
|
adaptation of signaling pathway
|
GO:0023058 |
7 |
0.542
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.540
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
1 |
0.540
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.532
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.529
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.528
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.522
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.521
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.519
|
|
|
|
system process
|
GO:0003008 |
349 |
0.517
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.512
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.511
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.509
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.508
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.501
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.497
|
|
|
|
regulation of blood volume by renin angiotensin
|
GO:0002016 |
1 |
0.494
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.494
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.493
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.488
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.486
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.485
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.482
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.477
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.472
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
6 |
0.470
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.462
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.455
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.453
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.449
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.447
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.435
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.435
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.434
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.431
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.428
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.416
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.414
|
Mouse |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.412
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.404
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.403
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.402
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.398
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.396
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.393
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.388
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.388
|
Human |
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.386
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.384
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.382
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.379
|
Mouse |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.372
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.371
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.369
|
Mouse |
|
|
negative regulation of nucleotide catabolic process
|
GO:0030812 |
16 |
0.366
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.364
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.364
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.361
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.359
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.359
|
Mouse |
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.352
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.351
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.350
|
|
|
|
hair follicle placode formation
|
GO:0060789 |
1 |
0.343
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.342
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.341
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.339
|
Human Mouse |
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.338
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.329
|
|
|
|
negative regulation of smooth muscle cell apoptotic process
|
GO:0034392 |
3 |
0.329
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.327
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.323
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.317
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.316
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.314
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.311
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.311
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.306
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.303
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.301
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.300
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.300
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.299
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.296
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.295
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.294
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.293
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.288
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.287
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.284
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.284
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.282
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.281
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.277
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.276
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.272
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.269
|
|
|
|
aging
|
GO:0007568 |
66 |
0.269
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.268
|
Mouse |
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.267
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.263
|
|
|
|
angiotensin activated signaling pathway
|
GO:0038166 |
4 |
0.263
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.260
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.251
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.250
|
|
|
|
regulation of granzyme a production
|
GO:2000511 |
1 |
0.248
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.246
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.246
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.245
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.244
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.244
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.241
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.240
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.237
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.236
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.235
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.235
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.233
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.231
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.227
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.222
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.221
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.221
|
|
|
|
detection of external stimulus
|
GO:0009581 |
15 |
0.220
|
Mouse |
|
|
response to ketone
|
GO:1901654 |
19 |
0.219
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.218
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.218
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.217
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.216
|
|
|
|
positive regulation of neurotransmitter transport
|
GO:0051590 |
1 |
0.214
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
14 |
0.213
|
Human |
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.209
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.209
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.209
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.209
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.207
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.207
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.205
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.205
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.204
|
Human |
|
|
muscle cell apoptotic process
|
GO:0010657 |
11 |
0.203
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.202
|
|
|
|
negative regulation of neurotrophin trk receptor signaling pathway
|
GO:0051387 |
2 |
0.201
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.200
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.195
|
|
|
|
mucosal immune response
|
GO:0002385 |
21 |
0.194
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.189
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.189
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.188
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.187
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.187
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.186
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.183
|
|
|
|
acetylcholine transport
|
GO:0015870 |
1 |
0.183
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.183
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.182
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.182
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.179
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.177
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.176
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.174
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.173
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.172
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.168
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.168
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.168
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.167
|
|
|
|
renin secretion into blood stream
|
GO:0002001 |
1 |
0.167
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.166
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.165
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.165
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.165
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.165
|
|
|
|
sensory perception of temperature stimulus
|
GO:0050951 |
1 |
0.163
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.163
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.162
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.161
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.160
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.159
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.158
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.158
|
Human |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.156
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.155
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.155
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.154
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.154
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.154
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.153
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.153
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.151
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.150
|
Mouse |
|
|
developmental pigmentation
|
GO:0048066 |
12 |
0.148
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.148
|
Mouse |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.148
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.147
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.147
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.146
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.145
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.145
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.145
|
Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.143
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.142
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.142
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.141
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.140
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.140
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.139
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.139
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.139
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
19 |
0.139
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.138
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.136
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
2 |
0.136
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.136
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.135
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.135
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.134
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.132
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.131
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.131
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.131
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.130
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.130
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.130
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.130
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.129
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.129
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.127
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.127
|
Worm |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.126
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.125
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.124
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.123
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.122
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.122
|
|
|
|
negative regulation of c c chemokine binding
|
GO:2001264 |
1 |
0.121
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.120
|
|
