IMP

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Mus musculus

0 genes annotated in mouse

lower respiratory tract disease

DOID:0050161

A respiratory system disease which involves the lower respiratory tract.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lower respiratory tract disease" (in gray)

Name	Description	Probability	Func Analog Organism
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1.000	Human
Atp6v1c2	ATPase, H+ transporting, lysosomal V1 subunit C2	0.266
Plunc	palate, lung, and nasal epithelium associated	0.197
Scnn1b	sodium channel, nonvoltage-gated 1 beta	0.193	Human
Ubxn10	UBX domain protein 10	0.170
Slc26a3	solute carrier family 26, member 3	0.159
Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.145
Clic3	chloride intracellular channel 3	0.138
Klf5	Kruppel-like factor 5	0.138
Il1rn	interleukin 1 receptor antagonist	0.128
Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	0.114
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.101
Gabrp	gamma-aminobutyric acid (GABA) A receptor, pi	0.097
Sftpd	surfactant associated protein D	0.088
Foxa2	forkhead box A2	0.087
Atp6v1b1	ATPase, H+ transporting, lysosomal V1 subunit B1	0.084
Marveld3	MARVEL (membrane-associating) domain containing 3	0.079
Wnk4	WNK lysine deficient protein kinase 4	0.076
Tgfb1	transforming growth factor, beta 1	0.073
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.070
Tspan1	tetraspanin 1	0.068
Cxcl15	chemokine (C-X-C motif) ligand 15	0.068
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.062	Human
Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	0.060
Prss8	protease, serine, 8 (prostasin)	0.055
Ace2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.053
4932425I24Rik	RIKEN cDNA 4932425I24 gene	0.051
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.048
2310007B03Rik	RIKEN cDNA 2310007B03 gene	0.045
Scgb3a2	secretoglobin, family 3A, member 2	0.044
Slc6a14	solute carrier family 6 (neurotransmitter transporter), member 14	0.041
Rnf186	ring finger protein 186	0.039
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.039
Mycbpap	MYCBP associated protein	0.038
Scnn1g	sodium channel, nonvoltage-gated 1 gamma	0.037	Human
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.037
Muc4	mucin 4	0.035
Dnahc5	dynein, axonemal, heavy chain 5	0.034
Slc19a3	solute carrier family 19 (sodium/hydrogen exchanger), member 3	0.032
Pof1b	premature ovarian failure 1B	0.030
Tmprss2	transmembrane protease, serine 2	0.029
Nkx2-1	NK2 homeobox 1	0.028
Sftpa1	surfactant associated protein A1	0.028	Human
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.027
Kcne2	potassium voltage-gated channel, Isk-related subfamily, gene 2	0.026
Calml3	calmodulin-like 3	0.025
Muc5b	mucin 5, subtype B, tracheobronchial	0.025	Human
Litaf	LPS-induced TN factor	0.024
Grhl2	grainyhead-like 2 (Drosophila)	0.024
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.023
Epn3	epsin 3	0.022
Slc44a3	solute carrier family 44, member 3	0.022
Tctex1d4	Tctex1 domain containing 4	0.020
F10	coagulation factor X	0.019
Spag6	sperm associated antigen 6	0.019
Bnipl	BCL2/adenovirus E1B 19kD interacting protein like	0.019
Upk3a	uroplakin 3A	0.019
Hnf1b	HNF1 homeobox B	0.018
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.017
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.016
Irx2	Iroquois related homeobox 2 (Drosophila)	0.016
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.016
Fbrs	fibrosin	0.016
Dab2	disabled homolog 2 (Drosophila)	0.015
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.015
Defb8	defensin beta 8	0.015
Tyrobp	TYRO protein tyrosine kinase binding protein	0.014
Phgr1	proline/histidine/glycine-rich 1	0.014
Pcdhb4	protocadherin beta 4	0.014
Agr3	anterior gradient homolog 3 (Xenopus laevis)	0.014
Chst4	carbohydrate (chondroitin 6/keratan) sulfotransferase 4	0.014
Muc1	mucin 1, transmembrane	0.014
Tbx4	T-box 4	0.014
Lrp2	low density lipoprotein receptor-related protein 2	0.014
Ptgs2	prostaglandin-endoperoxide synthase 2	0.013
Atoh8	atonal homolog 8 (Drosophila)	0.013
Cldn7	claudin 7	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Ccdc65	coiled-coil domain containing 65	0.013
Vtcn1	V-set domain containing T cell activation inhibitor 1	0.013
Tmprss4	transmembrane protease, serine 4	0.012
Agr2	anterior gradient 2 (Xenopus laevis)	0.012
Stx19	syntaxin 19	0.012
Tlr13	toll-like receptor 13	0.012
Cldn3	claudin 3	0.012
Myo5c	myosin VC	0.012
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
Cst11	cystatin 11	0.012
Slc5a8	solute carrier family 5 (iodide transporter), member 8	0.012
Cckar	cholecystokinin A receptor	0.011
2010005H15Rik	RIKEN cDNA 2010005H15 gene	0.011
Zmynd10	zinc finger, MYND domain containing 10	0.011
Ttc29	tetratricopeptide repeat domain 29	0.011
Mall	mal, T-cell differentiation protein-like	0.011
Mapk15	mitogen-activated protein kinase 15	0.011
Aox3	aldehyde oxidase 3	0.011
Foxa1	forkhead box A1	0.011
Trpm6	transient receptor potential cation channel, subfamily M, member 6	0.011
Cldn8	claudin 8	0.011
Prr15l	proline rich 15-like	0.011
Mfsd6l	major facilitator superfamily domain containing 6-like	0.011
Ano1	anoctamin 1, calcium activated chloride channel	0.010
Tmc5	transmembrane channel-like gene family 5	0.010
Chi3l3	chitinase 3-like 3	0.010