IMP
Process View
platelet activation
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "platelet activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Acta2 | smooth muscle alpha-actin | 0.354 | ||
| Actb | actin, beta | 0.135 | ||
| Ptafr | platelet-activating factor receptor | 0.095 | ||
| Flna | filamin A, alpha | 0.094 | ||
| Hck | hemopoietic cell kinase | 0.073 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.070 | ||
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.063 | Mouse | |
| Axl | Axl receptor tyrosine kinase | 0.061 | ||
| Gja1 | gap junction protein, alpha 1 | 0.059 | ||
| Edn1 | endothelin 1 | 0.047 | ||
| Scamp2 | secretory carrier membrane protein 2 | 0.047 | ||
| Arhgdib | Rho, GDP dissociation inhibitor (GDI) beta | 0.039 | ||
| Lst1 | leukocyte specific transcript 1 | 0.036 | ||
| Serpina10 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.035 | ||
| Itgb1 | integrin, beta 1 | 0.033 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.033 | ||
| Gmfg | glia maturation factor, gamma | 0.031 | ||
| Laptm5 | lysosomal protein transmembrane 5 | 0.030 | ||
| Cd4 | Cd4 molecule | 0.030 | ||
| Tpm3 | tropomyosin 3, gamma | 0.029 | ||
| Ahnak | AHNAK nucleoprotein | 0.028 | ||
| Tpm2 | tropomyosin 2, beta | 0.028 | ||
| Icam1 | intercellular adhesion molecule 1 | 0.027 | ||
| Tlr2 | toll-like receptor 2 | 0.026 | ||
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.025 | ||
| Cd37 | CD37 molecule | 0.025 | ||
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.024 | ||
| Tagln2 | transgelin 2 | 0.023 | ||
| Vav1 | vav 1 guanine nucleotide exchange factor | 0.022 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.022 | Human | |
| Tlr7 | toll-like receptor 7 | 0.021 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.021 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.019 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.019 | ||
| Arl11 | ADP-ribosylation factor-like 11 | 0.018 | ||
| Evi2a | ecotropic viral integration site 2A | 0.018 | ||
| Clic4 | chloride intracellular channel 4 | 0.017 | ||
| Homer3 | homer homolog 3 (Drosophila) | 0.017 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.017 | ||
| Cga | glycoprotein hormones, alpha polypeptide | 0.016 | ||
| Pycard | PYD and CARD domain containing | 0.016 | ||
| Lcp1 | lymphocyte cytosolic protein 1 | 0.016 | ||
| Bin2 | bridging integrator 2 | 0.016 | ||
| Fga | fibrinogen alpha chain | 0.016 | Human | |
| Ahsg | alpha-2-HS-glycoprotein | 0.015 | ||
| Nras | neuroblastoma ras oncogene | 0.015 | ||
| Ly86 | lymphocyte antigen 86 | 0.015 | ||
| Renbp | renin binding protein | 0.015 | ||
| Cx3cr1 | chemokine (C-X3-C motif) receptor 1 | 0.015 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.014 | ||
| Bcl2 | B-cell CLL/lymphoma 2 | 0.014 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.014 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.013 | ||
| Rhoc | ras homolog gene family, member C | 0.013 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.013 | ||
| Lrrc33 | leucine rich repeat containing 33 | 0.013 | ||
| Pzp | pregnancy-zone protein | 0.013 | ||
| Lepr | leptin receptor | 0.012 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.012 | ||
| Hmha1 | histocompatibility (minor) HA-1 | 0.012 | ||
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.011 | ||
| Klhl6 | kelch-like 6 (Drosophila) | 0.011 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.011 | ||
| Syt8 | synaptotagmin VIII | 0.011 | ||
| Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.011 | ||
| Atp2b4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.011 | ||
| Grin2b | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.011 | ||
| Ptbp1 | polypyrimidine tract binding protein 1 | 0.010 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.010 | ||
| Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.010 | ||
| Cd5 | Cd5 molecule | 0.010 |