The network for 'xenobiotic catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

xenobiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

Drosophila melanogaster
Name Description Probability Func Analog Organism
Ugt35a UDP-glycosyltransferase 35a 0.985
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.893
CG13310 CG13310 gene product from transcript CG13310-RA 0.874
JhI-26 Juvenile hormone-inducible protein 26 0.823
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.789
Cyp4e2 Cytochrome P450-4e2 0.764
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.758
CG9360 CG9360 gene product from transcript CG9360-RA 0.636
CG10562 CG10562 gene product from transcript CG10562-RA 0.603
Cyp6a9 Cytochrome P450-6a9 0.589
Cyp9b2 Cytochrome P450-9b2 0.503
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.498
CG4880 CG4880 gene product from transcript CG4880-RA 0.489
GstE6 Glutathione S transferase E6 0.484
CG6830 CG6830 gene product from transcript CG6830-RA 0.465
Cyp6d4 CG12800 gene product from transcript CG12800-RA 0.461
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.408
Cyp6a2 Cytochrome P450-6a2 0.395
Ugt86Da CG18578 gene product from transcript CG18578-RA 0.367
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.346
CG12672 CG12672 gene product from transcript CG12672-RA 0.341
CG6834 CG6834 gene product from transcript CG6834-RA 0.328
LvpD Larval visceral protein D 0.305
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.296
CG2064 CG2064 gene product from transcript CG2064-RA 0.292
CG7272 CG7272 gene product from transcript CG7272-RA 0.290
homer CG11324 gene product from transcript CG11324-RC 0.269
Ugt36Bc CG17932 gene product from transcript CG17932-RB 0.268
Cyp4p1 Cytochrome P450-4p1 0.252
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.218
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.194
Epac CG34392 gene product from transcript CG34392-RC 0.192
CG10560 CG10560 gene product from transcript CG10560-RA 0.192
CG10550 CG10550 gene product from transcript CG10550-RB 0.188
CG3759 CG3759 gene product from transcript CG3759-RB 0.188
fusl fuseless 0.186
CG7730 CG7730 gene product from transcript CG7730-RC 0.183
Cyp9f2 CG11466 gene product from transcript CG11466-RB 0.182
Acph-1 Acid phosphatase 1 0.181
Jheh3 Juvenile hormone epoxide hydrolase 3 0.176
CG4723 CG4723 gene product from transcript CG4723-RA 0.175
TotA Turandot A 0.170
Jheh1 Juvenile hormone epoxide hydrolase 1 0.160
CG16898 CG16898 gene product from transcript CG16898-RA 0.159
Est-Q Esterase Q 0.159
CG14457 CG14457 gene product from transcript CG14457-RA 0.158
sni sniffer 0.153
CG4630 CG4630 gene product from transcript CG4630-RA 0.152
Ilp4 Insulin-like peptide 4 0.147
CG11149 CG11149 gene product from transcript CG11149-RD 0.143
CG7979 CG7979 gene product from transcript CG7979-RA 0.141
CG6908 CG6908 gene product from transcript CG6908-RA 0.134
Doc3 Dorsocross3 0.130
Rh50 CG7499 gene product from transcript CG7499-RA 0.129
CG6465 CG6465 gene product from transcript CG6465-RA 0.128
CG9512 CG9512 gene product from transcript CG9512-RA 0.127
Vha68-1 CG12403 gene product from transcript CG12403-RA 0.126
Ugt86Dd CG6633 gene product from transcript CG6633-RB 0.125
mus81 CG3026 gene product from transcript CG3026-RA 0.123
Ugt86Dh CG4772 gene product from transcript CG4772-RA 0.119
CG13407 CG13407 gene product from transcript CG13407-RA 0.117
CG30494 CG30494 gene product from transcript CG30494-RA 0.116
CG15408 CG15408 gene product from transcript CG15408-RA 0.113
Syx4 Syntaxin 4 0.112
Cyp6a8 Cytochrome P450-6a8 0.111
CG15784 CG15784 gene product from transcript CG15784-RA 0.111
Ugt86Dj CG15902 gene product from transcript CG15902-RA 0.108
CG5361 CG5361 gene product from transcript CG5361-RA 0.105
CG4653 CG4653 gene product from transcript CG4653-RA 0.105
alpha-Est7 alpha-Esterase-7 0.104
Ugt86Dc CG4739 gene product from transcript CG4739-RA 0.103
GstE3 Glutathione S transferase E3 0.102
CG13658 CG13658 gene product from transcript CG13658-RB 0.100
CG4302 CG4302 gene product from transcript CG4302-RA 0.097
CG8679 CG8679 gene product from transcript CG8679-RA 0.095
CG5999 CG5999 gene product from transcript CG5999-RB 0.094
Ilp2 Insulin-like peptide 2 0.094
CG11967 CG11967 gene product from transcript CG11967-RA 0.093
CG16732 CG16732 gene product from transcript CG16732-RB 0.091
Cyp4ac3 CG14031 gene product from transcript CG14031-RA 0.091
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.088
CG17109 CG17109 gene product from transcript CG17109-RA 0.087
Cyp9b1 Cytochrome P450-9b1 0.087
CG15661 CG15661 gene product from transcript CG15661-RA 0.087
Cyp9h1 CG17577 gene product from transcript CG17577-RA 0.087
nAcRalpha-96Aa nicotinic Acetylcholine Receptor alpha 96Aa 0.086
CG3301 CG3301 gene product from transcript CG3301-RB 0.085
CG5724 CG5724 gene product from transcript CG5724-RA 0.084
GstE5 Glutathione S transferase E5 0.083
Tsp42Ed Tetraspanin 42Ed 0.082
CG14856 CG14856 gene product from transcript CG14856-RA 0.081
CG17028 CG17028 gene product from transcript CG17028-RA 0.079
nimB2 nimrod B2 0.079
CG5819 CG5819 gene product from transcript CG5819-RA 0.076
NaCP60E Na channel protein 60E 0.075
CG31104 CG31104 gene product from transcript CG31104-RA 0.075
CG6656 CG6656 gene product from transcript CG6656-RA 0.074
CG5527 CG5527 gene product from transcript CG5527-RA 0.073
CG17739 CG17739 gene product from transcript CG17739-RA 0.073
CG1387 CG1387 gene product from transcript CG1387-RA 0.073
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
GSTM2 glutathione S-transferase mu 2 (muscle) 0.999
GSTM4 glutathione S-transferase mu 4 0.948
GSTM1 glutathione S-transferase mu 1 0.933
GSTM3 glutathione S-transferase mu 3 (brain) 0.050
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.028
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.013
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Mus musculus
Name Description Probability Func Analog Organism
Gstm1 glutathione S-transferase, mu 1 0.996
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.991
Fmo5 flavin containing monooxygenase 5 0.980
Gstm3 glutathione S-transferase, mu 3 0.977
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.965
Otc ornithine transcarbamylase 0.965
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.963
Gsta3 glutathione S-transferase, alpha 3 0.959
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.897
Gstm6 glutathione S-transferase, mu 6 0.833
Gm3776 predicted gene 3776 0.830
Gsta4 glutathione S-transferase, alpha 4 0.826
Sult1d1 sulfotransferase family 1D, member 1 0.825
Ces1d carboxylesterase 1D 0.744
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.660
Ces1g carboxylesterase 1G 0.630
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.620
Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 0.608
Cps1 carbamoyl-phosphate synthetase 1 0.588
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.555
Ephx1 epoxide hydrolase 1, microsomal 0.551
Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 0.503
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.487
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.462
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 0.457
Gstt1 glutathione S-transferase, theta 1 0.442
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.399
Gstm4 glutathione S-transferase, mu 4 0.386
Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B 0.353
Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 0.290
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.289
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.287
Aass aminoadipate-semialdehyde synthase 0.279
Tmem205 transmembrane protein 205 0.262
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.231
Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.226
Defb1 defensin beta 1 0.215
Iyd iodotyrosine deiodinase 0.214
Adh1 alcohol dehydrogenase 1 (class I) 0.213
Gstm2 glutathione S-transferase, mu 2 0.202
Sult1b1 sulfotransferase family 1B, member 1 0.192
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.188
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.182
Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 0.167
Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 0.156
Galm galactose mutarotase 0.139
Ces2g carboxylesterase 2G 0.138
G6pc glucose-6-phosphatase, catalytic 0.136
Pik3c2g phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide 0.133
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.132
Cfhr1 complement factor H-related 1 0.130
S100a1 S100 calcium binding protein A1 0.124
Nqo1 NAD(P)H dehydrogenase, quinone 1 0.122
Dpyd dihydropyrimidine dehydrogenase 0.121
Vsig4 V-set and immunoglobulin domain containing 4 0.118
Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 0.118
Akr1d1 aldo-keto reductase family 1, member D1 0.116
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.114
Akr1c6 aldo-keto reductase family 1, member C6 0.107
Mgst1 microsomal glutathione S-transferase 1 0.105
Inmt indolethylamine N-methyltransferase 0.101
Tdo2 tryptophan 2,3-dioxygenase 0.099
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.099
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.097
Pon1 paraoxonase 1 0.094
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 0.092
Selenbp1 selenium binding protein 1 0.092
Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 0.092
Rdh7 retinol dehydrogenase 7 0.091
Cmbl carboxymethylenebutenolidase-like (Pseudomonas) 0.084
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.083
Ces1e carboxylesterase 1E 0.081
Pxmp2 peroxisomal membrane protein 2 0.080
Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A 0.079
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.075
Gstk1 glutathione S-transferase kappa 1 0.074
Crp C-reactive protein, pentraxin-related 0.070
Slco1b2 solute carrier organic anion transporter family, member 1b2 0.068
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.067
Bche butyrylcholinesterase 0.067
Ces2e carboxylesterase 2E 0.066
Mpzl2 myelin protein zero-like 2 0.063
Bbox1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase) 0.062
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.055
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.054
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.053
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35 0.051
Pm20d1 peptidase M20 domain containing 1 0.050
Cyp4a12a cytochrome P450, family 4, subfamily a, polypeptide 12a 0.050
Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 0.048
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.048
Alb albumin 0.048
Aldob aldolase B, fructose-bisphosphate 0.047
Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 0.046
Retsat retinol saturase (all trans retinol 13,14 reductase) 0.046
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 0.046
Copz2 coatomer protein complex, subunit zeta 2 0.045
Slc22a18 solute carrier family 22 (organic cation transporter), member 18 0.044
Nat1 N-acetyl transferase 1 0.044
Bhmt betaine-homocysteine methyltransferase 0.044
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Rattus norvegicus
Name Description Probability Func Analog Organism
Gstm1 glutathione S-transferase mu 1 1.000
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.975
Ephx1 epoxide hydrolase 1, microsomal 0.938
Mgst1 microsomal glutathione S-transferase 1 0.827
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.753
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.614
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.562
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.552
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.545
Mgst2 microsomal glutathione S-transferase 2 0.515
Gsta5 glutathione S-transferase Yc2 subunit 0.432
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.364
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.267
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.234
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.219
Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 0.207
Gstp1 glutathione S-transferase pi 1 0.205
Gsta2 glutathione S-transferase A2 0.174
Gsta3 glutathione S-transferase A3 0.163
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.157
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.153
Otc ornithine carbamoyltransferase 0.115
LOC494499 LOC494499 protein 0.108
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.108
Ces1c carboxylesterase 1C 0.105
Ces1e carboxylesterase 1E 0.099
Akr7a3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.098
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 0.089
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.089
LOC293989 cytochrome P450-like 0.078
Apob apolipoprotein B 0.077
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.076
Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 0.073
Gstm2 glutathione S-transferase mu 2 0.070
Cyb5a cytochrome b5 type A (microsomal) 0.068
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.057
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.051
Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.048
Akr1c14 aldo-keto reductase family 1, member C14 0.048
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.048
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.048
LOC100361864 UDP-glucuronosyltransferase 2B3-like 0.047
Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 0.047
Pctp phosphatidylcholine transfer protein 0.046
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.043
Ces1f carboxylesterase 1F 0.042
Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 0.042
Il1a interleukin 1 alpha 0.038
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.033
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.033
Cyb5r3 cytochrome b5 reductase 3 0.032
Selenbp1 selenium binding protein 1 0.031
Fabp1 fatty acid binding protein 1, liver 0.030
Fabp2 fatty acid binding protein 2, intestinal 0.030
Nat2 N-acetyltransferase 2 0.030
Dhfr dihydrofolate reductase 0.026
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.026
Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 0.026
Slco1a5 solute carrier organic anion transporter family, member 1a5 0.025
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.024
Clca4 chloride channel accessory 4 0.024
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.023
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.022
Znf394 zinc finger protein 394 0.021
Pigr polymeric immunoglobulin receptor 0.021
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.019
Gstm7 glutathione S-transferase, mu 7 0.019
Nqo1 NAD(P)H dehydrogenase, quinone 1 0.019
Vom1r102 vomeronasal 1 receptor 102 0.018
Mbl2 mannose-binding lectin (protein C) 2 0.018
LOC100365112 carboxylesterase-like 0.018
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.018
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.018
Sult1c3 sulfotransferase family, cytosolic, 1C, member 3 0.017
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.016
Acaa1b acetyl-Coenzyme A acyltransferase 1B 0.016
Dnah1 dynein, axonemal, heavy chain 1 0.016
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.016
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.015
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 0.015
Klkb1 kallikrein B, plasma 1 0.014
Aadac arylacetamide deacetylase (esterase) 0.014
Si sucrase-isomaltase (alpha-glucosidase) 0.014
Gstt1 glutathione S-transferase theta 1 0.014
Klrc2 killer cell lectin-like receptor subfamily C, member 2 0.013
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.013
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 0.013
Ugt1a8 UDP glycosyltransferase 1 family, polypeptide A8 0.012
Akr1c18 aldo-keto reductase family 1, member C18 0.012
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.012
S100a1 S100 calcium binding protein A1 0.011
Gstm5 glutathione S-transferase, mu 5 0.011
Aqp9 aquaporin 9 0.011
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.011
Dpyd dihydropyrimidine dehydrogenase 0.011
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.011
Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 0.011
Cd46 CD46 molecule, complement regulatory protein 0.011
Qdpr quinoid dihydropteridine reductase 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism