The network for 'negative regulation of vulval development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of vulval development

Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.

Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.999
hcp-3 Protein HCP-3 0.923
hlh-2 Protein HLH-2 0.907
CELE_Y41E3.11 Protein Y41E3.11 0.895
ldb-1 Protein LDB-1 0.873
npp-4 Protein NPP-4 0.857
snr-4 Protein SNR-4 0.857
pry-1 Protein PRY-1 0.857
eor-1 Protein EOR-1 0.789
CELE_Y54G11A.11 Protein Y54G11A.11 0.785
mep-1 Protein MEP-1 0.784
egl-27 Protein EGL-27 0.775
snr-2 Protein SNR-2 0.764
mix-1 Protein MIX-1 0.739
lin-36 Protein LIN-36 0.738
eps-8 Protein EPS-8 0.733
T09B4.2 Protein T09B4.2 0.728
lig-1 Protein LIG-1 0.712
T11G6.8 Protein T11G6.8 0.705
emb-5 Protein EMB-5 0.700
npp-1 Protein NPP-1 0.689
sur-2 Protein SUR-2 0.688
cdt-2 Protein CDT-2 0.676
rpb-11 Protein RPB-11 0.666
F08B4.7 Protein F08B4.7 0.666
mab-5 Protein MAB-5 0.651
hrpf-2 Protein HRPF-2 0.649
dpy-22 Protein DPY-22 0.648
unc-62 Protein UNC-62 0.628
snr-6 Protein SNR-6 0.625
npp-5 Protein NPP-5 0.619
rbd-1 Protein RBD-1 0.614
F35G12.4 Protein F35G12.4 0.612
mes-3 Protein MES-3 0.610
mcm-7 Protein MCM-7 0.606
lin-25 Protein LIN-25 0.600
athp-2 Protein ATHP-2 0.598
pha-4 Protein PHA-4 0.598
rpn-1 Protein RPN-1 0.597
sas-4 Protein SAS-4 0.583
cdk-8 Protein CDK-8 0.583
mes-4 Protein MES-4 0.581
lin-37 Protein LIN-37 0.576
fkh-2 Protein FKH-2 0.574
npp-7 Protein NPP-7 0.574
set-2 Protein SET-2 0.562
snr-1 Protein SNR-1 0.556
rnr-1 Protein RNR-1 0.556
CELE_C17H12.13 Protein C17H12.13 0.550
swsn-2.1 Protein SWSN-2.1 0.547
hlh-30 Protein HLH-30 0.545
pde-4 Protein PDE-4 0.543
dre-1 Protein DRE-1 0.541
CELE_Y73F8A.25 Protein Y73F8A.25 0.530
pole-2 Protein POLE-2 0.526
egl-8 Protein EGL-8 0.517
CELE_B0238.11 Protein B0238.11 0.511
CELE_F19F10.9 Protein F19F10.9 0.508
mog-4 Protein MOG-4 0.505
pqn-65 Protein PQN-65 0.504
lin-9 Protein LIN-9 0.504
skp-1 Protein SKP-1 0.499
fasn-1 Protein FASN-1 0.496
vab-3 Protein VAB-3 0.494
ZK930.1 Protein ZK930.1 0.492
C02B10.4 Protein C02B10.4 0.491
rpn-12 Protein RPN-12 0.489
lst-3 Protein LST-3 0.489
smc-3 Protein SMC-3 0.487
pbs-7 Protein PBS-7 0.483
ZC506.1 Protein ZC506.1 0.477
lin-59 Protein LIN-59 0.473
wnk-1 Protein WNK-1 0.472
lin-53 Protein LIN-53 0.470
hbl-1 Protein HBL-1 0.469
lin-12 Protein LIN-12 0.469
zen-4 Protein ZEN-4 0.468
mdt-8 Protein MDT-8 0.467
gpr-1 Protein GPR-1 0.465
mig-5 Protein MIG-5 0.464
gex-3 Protein GEX-3 0.463
W04D2.6 Protein W04D2.6 0.460
mat-3 Protein MAT-3 0.459
B0511.12 Protein B0511.12 0.457
smo-1 Protein SMO-1 0.457
sma-6 Protein SMA-6 0.456
wrm-1 Protein WRM-1 0.447
pbrm-1 Protein PBRM-1 0.447
gex-2 Protein GEX-2 0.445
cdtl-7 Protein CDTL-7 0.433
hda-1 Protein HDA-1 0.432
CELE_C55A6.9 Protein C55A6.9 0.425
sel-12 Protein SEL-12 0.424
lin-35 Protein LIN-35 0.424
rsp-1 Protein RSP-1 0.422
vab-1 Protein VAB-1 0.421
CELE_Y41D4B.11 Protein Y41D4B.11 0.418
csn-1 Protein CSN-1 0.417
rsp-5 Protein RSP-5 0.413
snrp-200 Protein SNRP-200 0.409
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism