The network for 'chronological cell aging' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chronological cell aging

The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MOB1 Mob1p 0.047
VHS1 Vhs1p 0.039
YPK2 Ypk2p 0.023
DBF2 Dbf2p 0.023
MSN4 Msn4p 0.022
GAT2 Gat2p 0.022
ACH1 Ach1p 0.021
ACE2 Ace2p 0.021
FPR1 Fpr1p 0.021
RIM13 Rim13p 0.020
IRC8 Irc8p 0.020
YAK1 Yak1p 0.020
GIS4 Gis4p 0.020
RTG3 Rtg3p 0.019
TRA1 Tra1p 0.019
HSP60 Hsp60p 0.019
YKR075C hypothetical protein 0.018
HUG1 Hug1p 0.018
RAD28 Rad28p 0.018
HAL5 Hal5p 0.018
IZH3 Izh3p 0.018
FRK1 Frk1p 0.018
BCK2 Bck2p 0.018
SUM1 Sum1p 0.017
CKB1 Ckb1p 0.017
TOR1 Tor1p 0.017
CSR2 Csr2p 0.017
INP52 Inp52p 0.017
ROX1 Rox1p 0.017
CBK1 Cbk1p 0.017
GLN3 Gln3p 0.016
PHM8 Phm8p 0.016
DBF20 Dbf20p 0.016
RMA1 Rma1p 0.016
ATG2 Atg2p 0.016
YPL014W hypothetical protein 0.016
SOG2 Sog2p 0.016
GUT2 Gut2p 0.016
HHO1 Hho1p 0.016
VID24 Vid24p 0.016
AVO1 Avo1p 0.016
RFM1 Rfm1p 0.015
YKL187C hypothetical protein 0.015
POG1 Pog1p 0.015
CAT8 Cat8p 0.015
NUP157 Nup157p 0.015
SRV2 Srv2p 0.015
YCL021W-A hypothetical protein 0.015
YCL042W hypothetical protein 0.015
NDE1 Nde1p 0.014
DNM1 Dnm1p 0.014
KGD1 Kgd1p 0.014
PHO2 Pho2p 0.014
RLM1 Rlm1p 0.014
FZO1 Fzo1p 0.014
LYS5 Lys5p 0.014
DFG16 Dfg16p 0.014
FMP48 Fmp48p 0.014
CTK1 Ctk1p 0.014
HAA1 Haa1p 0.014
ARP4 Arp4p 0.014
MDS3 Mds3p 0.014
CRZ1 Crz1p 0.014
PRK1 Prk1p 0.014
HAP4 Hap4p 0.014
MDV1 Mdv1p 0.014
HSV2 Hsv2p 0.014
XDJ1 Xdj1p 0.014
GIS3 Gis3p 0.014
TOR2 Tor2p 0.013
ZWF1 Zwf1p 0.013
RIP1 Rip1p 0.013
TPM1 Tpm1p 0.013
YPR157W hypothetical protein 0.013
FRE7 Fre7p 0.013
ZAP1 Zap1p 0.013
SIN3 Sin3p 0.013
KIC1 Kic1p 0.013
GIS1 Gis1p 0.013
PCD1 Pcd1p 0.013
TSC11 Tsc11p 0.013
MCA1 Mca1p 0.013
NDI1 Ndi1p 0.013
ATG29 Atg29p 0.013
CDC25 Cdc25p 0.013
FUS3 Fus3p 0.013
VMA13 Vma13p 0.013
HHT2 Hht2p 0.013
MTL1 Mtl1p 0.013
MSN2 Msn2p 0.013
ARG8 Arg8p 0.013
PST1 Pst1p 0.013
FAR3 Far3p 0.013
ARG81 Arg81p 0.012
HST3 Hst3p 0.012
TYE7 Tye7p 0.012
RGS2 Rgs2p 0.012
GZF3 Gzf3p 0.012
RCO1 Rco1p 0.012
YNL234W hypothetical protein 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ACTB actin, beta 0.903
CFL1 cofilin 1 (non-muscle) 0.688
ZYX zyxin 0.405
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.252
CFL2 cofilin 2 (muscle) 0.206
PLAU plasminogen activator, urokinase 0.203
FLNA filamin A, alpha 0.124
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) 0.117
TPM1 tropomyosin 1 (alpha) 0.112
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.099
TGFB1 transforming growth factor, beta 1 0.092
TPM4 tropomyosin 4 0.082
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.073
ACTN1 actinin, alpha 1 0.065
MYH9 myosin, heavy chain 9, non-muscle 0.060
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.059
PLAT plasminogen activator, tissue 0.057
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.055
HIST1H3B histone cluster 1, H3b 0.038
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.038
FN1 fibronectin 1 0.036
LMNA lamin A/C 0.033
TUBA1C tubulin, alpha 1c 0.033
ACTG1 actin, gamma 1 0.032
MYL9 myosin, light chain 9, regulatory 0.029
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.029
USP46 ubiquitin specific peptidase 46 0.028
SNX9 sorting nexin 9 0.027
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.025
WDR1 WD repeat domain 1 0.024
WDR48 WD repeat domain 48 0.024
DTX1 deltex homolog 1 (Drosophila) 0.024
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.022
CSRP1 cysteine and glycine-rich protein 1 0.020
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.020
CDK11A cyclin-dependent kinase 11A 0.018
ARRB2 arrestin, beta 2 0.017
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.017
PLAUR plasminogen activator, urokinase receptor 0.017
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.015
PDLIM7 PDZ and LIM domain 7 (enigma) 0.015
PTRF polymerase I and transcript release factor 0.015
TGFB3 transforming growth factor, beta 3 0.015
ORM1 orosomucoid 1 0.015
SMCR7L Smith-Magenis syndrome chromosome region, candidate 7-like 0.015
GADD45G growth arrest and DNA-damage-inducible, gamma 0.014
CHD4 chromodomain helicase DNA binding protein 4 0.013
EHD2 EH-domain containing 2 0.012
SIRT5 sirtuin 5 0.012
VTN vitronectin 0.012
ZNHIT1 zinc finger, HIT-type containing 1 0.012
HDAC6 histone deacetylase 6 0.012
BCAP31 B-cell receptor-associated protein 31 0.012
SIRT4 sirtuin 4 0.011
TMSB4X thymosin beta 4, X-linked 0.011
FBRSL1 fibrosin-like 1 0.011
HIST1H4F histone cluster 1, H4f 0.011
SEC61B Sec61 beta subunit 0.011
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.011
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.011
SNX18 sorting nexin 18 0.011
OSBP oxysterol binding protein 0.011
CYR61 cysteine-rich, angiogenic inducer, 61 0.011
FSCN1 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) 0.010
PDAP1 PDGFA associated protein 1 0.010
MYH11 myosin, heavy chain 11, smooth muscle 0.010
MSN moesin 0.010
KIF5C kinesin family member 5C 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Cfl1 cofilin 1, non-muscle 0.648
Tpm4 tropomyosin 4 0.261
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.203
Myl9 myosin, light polypeptide 9, regulatory 0.171
Pfn1 profilin 1 0.132
Myh9 myosin, heavy polypeptide 9, non-muscle 0.117
Acvrl1 activin A receptor, type II-like 1 0.102
Rnf2 ring finger protein 2 0.095
Actg2 actin, gamma 2, smooth muscle, enteric 0.095
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.092
Kdm2b lysine (K)-specific demethylase 2B 0.087
Tmsb4x thymosin, beta 4, X chromosome 0.063
Tagln transgelin 0.060
Cotl1 coactosin-like 1 (Dictyostelium) 0.057
Tuba1a tubulin, alpha 1A 0.056
Arpc2 actin related protein 2/3 complex, subunit 2 0.055
Wdr1 WD repeat domain 1 0.047
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.047
Msn moesin 0.045
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.043
Tgfbr2 transforming growth factor, beta receptor II 0.043
Acta2 actin, alpha 2, smooth muscle, aorta 0.042
Smtn smoothelin 0.042
Lrrk2 leucine-rich repeat kinase 2 0.042
Cyr61 cysteine rich protein 61 0.038
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.037
Vasp vasodilator-stimulated phosphoprotein 0.037
Mylk myosin, light polypeptide kinase 0.036
Lgals1 lectin, galactose binding, soluble 1 0.035
Tuba1b tubulin, alpha 1B 0.032
Csrp1 cysteine and glycine-rich protein 1 0.029
Mks1 Meckel syndrome, type 1 0.028
Kdm1a lysine (K)-specific demethylase 1A 0.028
Cnn2 calponin 2 0.027
Actn1 actinin, alpha 1 0.027
Myo1c myosin IC 0.027
Cbx3 chromobox homolog 3 (Drosophila HP1 gamma) 0.024
Glipr2 GLI pathogenesis-related 2 0.023
Set SET nuclear oncogene 0.023
Igfbp3 insulin-like growth factor binding protein 3 0.021
Ilk integrin linked kinase 0.021
Clic1 chloride intracellular channel 1 0.021
Tmsb10 thymosin, beta 10 0.021
Myh11 myosin, heavy polypeptide 11, smooth muscle 0.020
Cxadr coxsackie virus and adenovirus receptor 0.019
Bcor BCL6 interacting corepressor 0.019
Flna filamin, alpha 0.019
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 0.018
Mgp matrix Gla protein 0.018
Dcaf7 DDB1 and CUL4 associated factor 7 0.018
Arid1b AT rich interactive domain 1B (SWI-like) 0.017
Cbx8 chromobox homolog 8 (Drosophila Pc class) 0.017
Fst follistatin 0.017
Kctd10 potassium channel tetramerisation domain containing 10 0.016
Tpm1 tropomyosin 1, alpha 0.016
Tubb5 tubulin, beta 5 0.016
Cnn1 calponin 1 0.016
Ptma prothymosin alpha 0.015
Ppia peptidylprolyl isomerase A 0.015
Kif5c kinesin family member 5C 0.015
Rhoc ras homolog gene family, member C 0.014
Capzb capping protein (actin filament) muscle Z-line, beta 0.014
Gpr98 G protein-coupled receptor 98 0.014
Csnk2a1 casein kinase 2, alpha 1 polypeptide 0.014
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.013
Lmod1 leiomodin 1 (smooth muscle) 0.013
Tinagl1 tubulointerstitial nephritis antigen-like 1 0.013
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 0.013
Gata3 GATA binding protein 3 0.013
Rpgrip1l Rpgrip1-like 0.013
Rhog ras homolog gene family, member G 0.013
Calm1 calmodulin 1 0.012
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.012
Ahi1 Abelson helper integration site 1 0.012
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.012
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.012
Dll4 delta-like 4 (Drosophila) 0.012
Fbxo32 F-box protein 32 0.012
Tpm3 tropomyosin 3, gamma 0.012
Icam2 intercellular adhesion molecule 2 0.012
Pcgf6 polycomb group ring finger 6 0.011
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.011
Clic4 chloride intracellular channel 4 (mitochondrial) 0.011
Rundc3a RUN domain containing 3A 0.011
Tpm2 tropomyosin 2, beta 0.011
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.011
Yaf2 YY1 associated factor 2 0.011
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.011
Basp1 brain abundant, membrane attached signal protein 1 0.011
Pum1 pumilio 1 (Drosophila) 0.011
Iqgap1 IQ motif containing GTPase activating protein 1 0.011
F2r coagulation factor II (thrombin) receptor 0.011
Dpep1 dipeptidase 1 (renal) 0.011
Rxra retinoid X receptor alpha 0.011
Crip1 cysteine-rich protein 1 (intestinal) 0.011
2900073G15Rik RIKEN cDNA 2900073G15 gene 0.011
Map3k6 mitogen-activated protein kinase kinase kinase 6 0.011
Gabarap gamma-aminobutyric acid receptor associated protein 0.011
Espn espin 0.011
2310014H01Rik RIKEN cDNA 2310014H01 gene 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism