IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

negative regulation of c c chemokine binding

GO:2001264

Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of c c chemokine binding"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of c c chemokine binding" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL2	chemokine (C-C motif) ligand 2	0.989	Human
CCL5	chemokine (C-C motif) ligand 5	0.982	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.974
CCL8	chemokine (C-C motif) ligand 8	0.970	Human
CCL4	chemokine (C-C motif) ligand 4	0.946	Human
IL6	interleukin 6 (interferon, beta 2)	0.939
IL8	interleukin 8	0.828
DPP4	dipeptidyl-peptidase 4	0.797
IFNG	interferon, gamma	0.733
CXCL10	chemokine (C-X-C motif) ligand 10	0.672
CCR1	chemokine (C-C motif) receptor 1	0.662
IL1B	interleukin 1, beta	0.640
IDE	insulin-degrading enzyme	0.639
CCL13	chemokine (C-C motif) ligand 13	0.608	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.590	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.568
CCL22	chemokine (C-C motif) ligand 22	0.564	Human
CCR7	chemokine (C-C motif) receptor 7	0.563
CCL19	chemokine (C-C motif) ligand 19	0.534	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.473
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.420
RGS1	regulator of G-protein signaling 1	0.377
CXCL13	chemokine (C-X-C motif) ligand 13	0.364
CCL7	chemokine (C-C motif) ligand 7	0.352	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.340
IL10	interleukin 10	0.292
TNF	tumor necrosis factor	0.267
CXCL11	chemokine (C-X-C motif) ligand 11	0.244
CD83	CD83 molecule	0.239
CCR4	chemokine (C-C motif) receptor 4	0.221
VCAM1	vascular cell adhesion molecule 1	0.207
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.202
SELE	selectin E	0.181
CD40	CD40 molecule, TNF receptor superfamily member 5	0.175
TRAF1	TNF receptor-associated factor 1	0.171
CXCL5	chemokine (C-X-C motif) ligand 5	0.143
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.130
CCL20	chemokine (C-C motif) ligand 20	0.123	Human
ARRB1	arrestin, beta 1	0.121
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.115
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.104
ICAM1	intercellular adhesion molecule 1	0.101
CCL11	chemokine (C-C motif) ligand 11	0.094	Human
DARC	Duffy blood group, chemokine receptor	0.088
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.077
IL2RB	interleukin 2 receptor, beta	0.075
GNLY	granulysin	0.072
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.069
FPR3	formyl peptide receptor 3	0.059
IL7R	interleukin 7 receptor	0.056
IL18RAP	interleukin 18 receptor accessory protein	0.056
CH25H	cholesterol 25-hydroxylase	0.052
IL2RG	interleukin 2 receptor, gamma	0.049
STAT4	signal transducer and activator of transcription 4	0.049
PI3	peptidase inhibitor 3, skin-derived	0.048
CCL21	chemokine (C-C motif) ligand 21	0.046
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.046
UBD	ubiquitin D	0.046
EBI3	Epstein-Barr virus induced 3	0.043
IL1RN	interleukin 1 receptor antagonist	0.042
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.040
SLAMF8	SLAM family member 8	0.039
CCR3	chemokine (C-C motif) receptor 3	0.038
LAMP3	lysosomal-associated membrane protein 3	0.038
ADAMDEC1	ADAM-like, decysin 1	0.038
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.037
IL21R	interleukin 21 receptor	0.036
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.036
CXCR6	chemokine (C-X-C motif) receptor 6	0.036
CCL3	chemokine (C-C motif) ligand 3	0.035	Human
BCL2A1	BCL2-related protein A1	0.034
CCL17	chemokine (C-C motif) ligand 17	0.034	Human
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.034
SLAMF7	SLAM family member 7	0.031
IDO1	indoleamine 2,3-dioxygenase 1	0.030
IL1R2	interleukin 1 receptor, type II	0.028
MSC	musculin	0.027
IL2RA	interleukin 2 receptor, alpha	0.027
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.027
NKG7	natural killer cell group 7 sequence	0.027
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.026
IL1A	interleukin 1, alpha	0.025
CXCR3	chemokine (C-X-C motif) receptor 3	0.024
CCRL2	chemokine (C-C motif) receptor-like 2	0.023
CTSW	cathepsin W	0.022
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.022
RGS16	regulator of G-protein signaling 16	0.020
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.020
CD69	CD69 molecule	0.020
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.020
INHBA	inhibin, beta A	0.019
PRF1	perforin 1 (pore forming protein)	0.018
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.018
IRF4	interferon regulatory factor 4	0.018
CD80	CD80 molecule	0.018
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.018
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.018
APOC1	apolipoprotein C-I	0.018
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.017
BATF	basic leucine zipper transcription factor, ATF-like	0.017
BIRC3	baculoviral IAP repeat containing 3	0.016
SLAMF1	signaling lymphocytic activation molecule family member 1	0.016
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.016
CD209	CD209 molecule	0.015
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.015
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.015
AQP9	aquaporin 9	0.015
C2	complement component 2	0.014
CD160	CD160 molecule	0.014
SRGN	serglycin	0.014
GPR171	G protein-coupled receptor 171	0.014
DNASE1L3	deoxyribonuclease I-like 3	0.014
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.014
SOD2	superoxide dismutase 2, mitochondrial	0.014
GZMK	granzyme K (granzyme 3; tryptase II)	0.014
CLEC10A	C-type lectin domain family 10, member A	0.013
IL13	interleukin 13	0.013
IGL@	immunoglobulin lambda locus	0.013
LAG3	lymphocyte-activation gene 3	0.012
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.012
RUNX3	runt-related transcription factor 3	0.012
LRRC32	leucine rich repeat containing 32	0.012
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.012
CSF1	colony stimulating factor 1 (macrophage)	0.012
CD1B	CD1b molecule	0.012
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
IL18R1	interleukin 18 receptor 1	0.011
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.011
PDPN	podoplanin	0.011
CCBP2	chemokine binding protein 2	0.011
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.011
PLEK	pleckstrin	0.011
CD40LG	CD40 ligand	0.011
GPR109B	G protein-coupled receptor 109B	0.011
TM7SF4	transmembrane 7 superfamily member 4	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
IL1F5	interleukin 1 family, member 5 (delta)	0.010
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.010
MMP19	matrix metallopeptidase 19	0.010
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.010
SOCS3	suppressor of cytokine signaling 3	0.010
CST7	cystatin F (leukocystatin)	0.010
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.010