|
|
membrane tubulation
|
GO:0097320 |
12 |
1.000
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.999
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.998
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.996
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.991
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.990
|
Human |
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.987
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.987
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.985
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.985
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.972
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.967
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.951
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.931
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.928
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.927
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.923
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.919
|
Fly |
|
|
actin nucleation
|
GO:0045010 |
21 |
0.916
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.914
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.905
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.895
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.893
|
Human |
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.885
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.883
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.882
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.871
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.849
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.844
|
|
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.842
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.838
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.830
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.826
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.824
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.816
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.815
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.813
|
|
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
0.810
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.794
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.781
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.781
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.770
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.766
|
Human |
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.744
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.743
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.738
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.734
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.728
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
0.727
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.725
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.722
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.721
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.719
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.712
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.697
|
Human |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.693
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.687
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.674
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.666
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.662
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.651
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.639
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.638
|
Human |
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.628
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.627
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.626
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.617
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.609
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.603
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.601
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.601
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.598
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.596
|
Human |
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.592
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.592
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.582
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.576
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.573
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.563
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.561
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.519
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.518
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.516
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.498
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.493
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.491
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.486
|
|
|
|
negative regulation of actin nucleation
|
GO:0051126 |
3 |
0.479
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.477
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.475
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.472
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.471
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.466
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.465
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.461
|
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.460
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.451
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.445
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.445
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.442
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.437
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.437
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.436
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.435
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.430
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.420
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.417
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.414
|
Human |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.403
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.402
|
Fly |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.402
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.397
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.397
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.397
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.395
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.387
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.379
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.378
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.377
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.376
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.370
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.370
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.359
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.351
|
Human |
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.351
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.350
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.348
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.346
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.337
|
Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.337
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.331
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.330
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.329
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.326
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.326
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.325
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.322
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.320
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.319
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.317
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.317
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.315
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.314
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.312
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.310
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.310
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.308
|
Human |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.305
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.301
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.298
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.297
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.292
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.290
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.288
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.287
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.286
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.285
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.283
|
Human |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.281
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.281
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.278
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.277
|
|
|
|
growth
|
GO:0040007 |
202 |
0.277
|
|
|
|
positive regulation of peptidyl serine phosphorylation of stat protein
|
GO:0033141 |
3 |
0.274
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.274
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.273
|
|
|
|
regulation of astrocyte chemotaxis
|
GO:2000458 |
1 |
0.272
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.272
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.270
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.270
|
Human |
|
|
chemokine c c motif ligand 19 signaling pathway
|
GO:0038115 |
1 |
0.267
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.267
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.264
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.262
|
|
|
|
regulation of cellular extravasation
|
GO:0002691 |
8 |
0.262
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.261
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.261
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.259
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.258
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.258
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.256
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.256
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.255
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.252
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.249
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.246
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.242
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.241
|
|
|
|
membrane assembly
|
GO:0071709 |
10 |
0.237
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.237
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.234
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.232
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.231
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.230
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.228
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.227
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.226
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.224
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.223
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.223
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.223
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.219
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.218
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.218
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.218
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.217
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.215
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.212
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.212
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.210
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.210
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.209
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.209
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.208
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.208
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.207
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.207
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.207
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.205
|
Human |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.205
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.204
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.204
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.202
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.202
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.200
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.194
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.193
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.190
|
|
|
|
activated t cell proliferation
|
GO:0050798 |
13 |
0.189
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.189
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.187
|
Human |
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.187
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.185
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.185
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.182
|
|
|
|
regulation of skeletal muscle cell proliferation
|
GO:0014857 |
1 |
0.182
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.180
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.179
|
Human |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.178
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.178
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.176
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.175
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.174
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.174
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.174
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.173
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.172
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.172
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.170
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.170
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.167
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.166
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.165
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.164
|
Fly |
|
|
organelle localization
|
GO:0051640 |
84 |
0.162
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.161
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.157
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.157
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.157
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.156
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.156
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.153
|
|
|
|
response to water
|
GO:0009415 |
2 |
0.153
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.153
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.153
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.152
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.152
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.151
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.151
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.150
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.150
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.150
|
Fly |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.149
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.149
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.148
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.147
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.146
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.146
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.145
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.144
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.143
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.142
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.142
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.142
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.141
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.141
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.140
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.140
|
|
|
|
head development
|
GO:0060322 |
108 |
0.138
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.136
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.136
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.135
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.135
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.135
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.135
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.135
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.133
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.133
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.132
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.132
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.132
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.131
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.129
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.129
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.129
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.126
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.126
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.125
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.125
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.123
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.122
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.121
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.119
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.119
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.119
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.117
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.117
|
Human |
|
|
cellular response to water stimulus
|
GO:0071462 |
1 |
0.116
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.116
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.116
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.115
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.114
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.114
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.113
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.112
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.111
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.110
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
13 |
0.110
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.109
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.109
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.108
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.107
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.107
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.106
|
Human |
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.106
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.105
|
|
|
|
cytokinetic process
|
GO:0032506 |
12 |
0.104
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.103
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.103
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.102
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.102
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.102
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.102
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.101
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.099
|
|
|
|
pulmonary vein morphogenesis
|
GO:0060577 |
1 |
0.099
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.096
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.095
|
|
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.095
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.094
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.094
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.094
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.094
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.093
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.093
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.092
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.092
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.091
|
Human |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.090
|
Human |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.090
|
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.089
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.089
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.087
|
|
|
|
interleukin 1 beta biosynthetic process
|
GO:0050720 |
2 |
0.087
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
11 |
0.086
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.085
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.084
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.084
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.084
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.084
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.084
|
Human |
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.083
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.082
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.082
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.082
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.082
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.081
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.080
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.079
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.079
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.079
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.079
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.079
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.079
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.079
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.079
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.078
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.078
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.077
|
Human |
|
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.076
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.075
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.075
|
|
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.075
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.075
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.074
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.074
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.073
|
Human |
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.073
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.073
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.073
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.073
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.073
|
Human |
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.073
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.071
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.070
|
Human |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.070
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.070
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.068
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.068
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.067
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.067
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.066
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.066
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.066
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.066
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.066
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.065
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.065
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.065
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.065
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.064
|
|
|
|
necroptotic process
|
GO:0070266 |
16 |
0.064
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.064
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.064
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.063
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.063
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.063
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.062
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.062
|
Human |
|
|
dendrite development
|
GO:0016358 |
24 |
0.062
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.061
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.060
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.060
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.060
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.060
|
Human |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.060
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.060
|
Human |
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.059
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.058
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.058
|
Human |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.058
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.058
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.058
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.057
|
Human |
|
|
astrocyte chemotaxis
|
GO:0035700 |
1 |
0.057
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.057
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.057
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.057
|
|
|
|
negative regulation of deoxyribonuclease activity
|
GO:0032076 |
1 |
0.056
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.056
|
Human |
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.056
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.055
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.055
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.054
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.054
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.054
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
19 |
0.054
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.054
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.054
|
|
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.054
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
5 |
0.053
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.053
|
|
|
|
positive regulation of protein localization to cell surface
|
GO:2000010 |
6 |
0.053
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.053
|
Fly |
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.053
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.053
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.053
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.052
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.052
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.051
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.051
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.051
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.051
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.050
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.050
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.050
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.050
|
Human |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.050
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.050
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.049
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.049
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.049
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.049
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
4 |
0.049
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.049
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.048
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.048
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.047
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.047
|
|
