IMP
Process View
signal transduction involved in mitotic cell cycle checkpoint
A signal transduction process that contributes to a mitotic cell cycle checkpoint.
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Click on a gene's description to view its network relationships with genes known to be involved in "signal transduction involved in mitotic cell cycle checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.997 | ||
| RB1 | retinoblastoma 1 | 0.995 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.995 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.993 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.990 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.972 | Human | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.972 | Human | |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.963 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.813 | ||
| BRCA1 | breast cancer 1, early onset | 0.626 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.624 | Human | |
| APAF1 | apoptotic peptidase activating factor 1 | 0.554 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.369 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.331 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.276 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.262 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.249 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.209 | ||
| TP53 | tumor protein p53 | 0.206 | Mouse | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.196 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.181 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.170 | Human | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.134 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.134 | ||
| LRDD | leucine-rich repeats and death domain containing | 0.128 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.117 | ||
| IER3 | immediate early response 3 | 0.114 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.114 | Human | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.111 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.109 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.106 | ||
| PAX3 | paired box 3 | 0.086 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.081 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.075 | Human | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.071 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.066 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.063 | Human | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.053 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.052 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.051 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.050 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.042 | ||
| GORAB | golgin, RAB6-interacting | 0.036 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.035 | Human | |
| SMAD7 | SMAD family member 7 | 0.033 | ||
| NOTCH1 | notch 1 | 0.030 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.030 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.028 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.027 | Human | |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) | 0.025 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.025 | ||
| RIOK3 | RIO kinase 3 (yeast) | 0.025 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.025 | Human | |
| CDK6 | cyclin-dependent kinase 6 | 0.023 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.023 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.022 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.022 | ||
| CCND1 | cyclin D1 | 0.022 | ||
| NUCB2 | nucleobindin 2 | 0.021 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.021 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.020 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.017 | ||
| SPRR2A | small proline-rich protein 2A | 0.017 | ||
| DAXX | death-domain associated protein | 0.017 | ||
| MARCKSL1 | MARCKS-like 1 | 0.016 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.016 | ||
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.015 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.015 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.014 | ||
| FOXD3 | forkhead box D3 | 0.014 | ||
| ATMIN | ATM interactor | 0.014 | ||
| YY1 | YY1 transcription factor | 0.014 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.014 | ||
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.013 | ||
| CCNE1 | cyclin E1 | 0.013 | ||
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.012 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.011 | ||
| HDAC4 | histone deacetylase 4 | 0.011 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.011 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.011 | ||
| BANP | BTG3 associated nuclear protein | 0.011 | ||
| MDFI | MyoD family inhibitor | 0.010 | ||
| CCND3 | cyclin D3 | 0.010 | ||
| TELO2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.010 |