IMP
Process View
macropinocytosis
An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "macropinocytosis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SNX9 | sorting nexin 9 | 0.989 | Human | |
| ADAM15 | ADAM metallopeptidase domain 15 | 0.939 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.937 | ||
| SNX33 | sorting nexin 33 | 0.760 | ||
| DNM1 | dynamin 1 | 0.261 | ||
| HSF1 | heat shock transcription factor 1 | 0.218 | ||
| DNM2 | dynamin 2 | 0.199 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.178 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.124 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.072 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.069 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.066 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.054 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.052 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.037 | ||
| ANKRD28 | ankyrin repeat domain 28 | 0.029 | ||
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.028 | ||
| CTTN | cortactin | 0.027 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.023 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.023 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.023 | ||
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.022 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.018 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.017 | ||
| AMPH | amphiphysin | 0.016 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.014 | ||
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.014 | ||
| SH3PXD2A | SH3 and PX domains 2A | 0.014 | ||
| DTX1 | deltex homolog 1 (Drosophila) | 0.014 | ||
| SYNJ1 | synaptojanin 1 | 0.013 | ||
| RNF11 | ring finger protein 11 | 0.012 | ||
| MEFV | Mediterranean fever | 0.012 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.012 |