Homo sapiens

8 known processes

MPDZ

multiple PDZ domain protein

(Aliases: FLJ25909,MUPP1,FLJ34626,DKFZp781P216,FLJ90240)

MPDZ biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 2 1.000
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 1.000
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 1.000
positive regulation of phosphatidylinositol biosynthetic process GO:0010513 3 1.000
phospholipase c activating adrenergic receptor signaling pathway GO:0071882 1 1.000
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 1 1.000
somatostatin receptor signaling pathway GO:0038169 1 1.000
positive regulation of camp mediated signaling GO:0043950 10 1.000
somatostatin signaling pathway GO:0038170 1 1.000
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 1.000
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 1.000
negative regulation of wnt protein secretion GO:0061358 1 1.000
serotonin receptor signaling pathway GO:0007210 11 1.000
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.999
opioid receptor signaling pathway GO:0038003 4 0.999
positive regulation of glucocorticoid secretion GO:2000851 4 0.999
regulation of large conductance calcium activated potassium channel activity GO:1902606 2 0.998
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 2 0.998
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.996
gastro intestinal system smooth muscle contraction GO:0014831 2 0.995
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 3 0.994
regulation of camp mediated signaling GO:0043949 13 0.988
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 6 0.986
positive regulation of cellular amine metabolic process GO:0033240 7 0.974
negative regulation of lipid catabolic process GO:0050995 9 0.972
regulation of cyclase activity GO:0031279 19 0.972
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.966
inositol lipid mediated signaling GO:0048017 55 0.964
activation of phospholipase c activity GO:0007202 7 0.959
regulation of cellular ketone metabolic process GO:0010565 50 0.957
vascular process in circulatory system GO:0003018 29 0.952
purine nucleoside triphosphate catabolic process GO:0009146 392 0.950
positive regulation of camp biosynthetic process GO:0030819 35 0.950
smooth muscle contraction GO:0006939 14 0.940
regulation of lipase activity GO:0060191 37 0.938
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.936
phosphatidylinositol mediated signaling GO:0048015 55 0.934
dopamine receptor signaling pathway GO:0007212 10 0.932
intestine smooth muscle contraction GO:0014827 2 0.925
regulation of hormone levels GO:0010817 125 0.921
receptor transactivation GO:0035624 4 0.920
cellular ketone metabolic process GO:0042180 80 0.914
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.910
positive regulation of phospholipid biosynthetic process GO:0071073 4 0.906
phospholipase c activating dopamine receptor signaling pathway GO:0060158 2 0.903
regulation of cellular amine metabolic process GO:0033238 11 0.901
negative regulation of secretion GO:0051048 58 0.894
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.891
regulation of cell migration GO:0030334 289 0.891
cellular response to oxygen containing compound GO:1901701 276 0.890
cellular hormone metabolic process GO:0034754 41 0.881
adenylate cyclase activating adrenergic receptor signaling pathway GO:0071880 3 0.881
camp metabolic process GO:0046058 61 0.877
cellular response to hormone stimulus GO:0032870 125 0.876
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.868
camp biosynthetic process GO:0006171 47 0.865
potassium ion transport GO:0006813 62 0.860
regulation of phospholipase c activity GO:1900274 14 0.860
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.852
nucleoside triphosphate metabolic process GO:0009141 422 0.849
cellular amino acid metabolic process GO:0006520 116 0.839
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.836
positive regulation of cortisol secretion GO:0051464 4 0.833
regulation of phosphatidylinositol biosynthetic process GO:0010511 5 0.830
cellular amine metabolic process GO:0044106 41 0.827
positive regulation of phosphorylation GO:0042327 394 0.820
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.819
cellular potassium ion transport GO:0071804 60 0.818
ribonucleoside catabolic process GO:0042454 406 0.817
wnt protein secretion GO:0061355 1 0.812
positive regulation of ion transport GO:0043270 87 0.811
regulation of calcium ion transport into cytosol GO:0010522 33 0.810
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.810
regulation of cellular amino acid metabolic process GO:0006521 6 0.810
ion homeostasis GO:0050801 230 0.809
regulation of nucleoside metabolic process GO:0009118 209 0.807
phasic smooth muscle contraction GO:0014821 6 0.804
immune response GO:0006955 307 0.798
amine metabolic process GO:0009308 44 0.795
positive regulation of cell substrate adhesion GO:0010811 37 0.790
negative regulation of insulin secretion GO:0046676 9 0.785
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.782
regulation of adenylate cyclase activity GO:0045761 17 0.779
nucleoside catabolic process GO:0009164 408 0.779
regulation of gtp catabolic process GO:0033124 180 0.767
positive regulation of fat cell differentiation GO:0045600 12 0.760
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.760
hippo signaling GO:0035329 20 0.757
cell matrix adhesion GO:0007160 85 0.752
glycerophospholipid metabolic process GO:0006650 84 0.751
positive regulation of camp metabolic process GO:0030816 41 0.748
regulation of nucleotide biosynthetic process GO:0030808 50 0.747
cellular metal ion homeostasis GO:0006875 146 0.747
regulation of lipid catabolic process GO:0050994 23 0.744
camp mediated signaling GO:0019933 23 0.743
hindbrain development GO:0030902 3 0.737
positive regulation of cellular component movement GO:0051272 181 0.735
cellular response to organic cyclic compound GO:0071407 127 0.734
cellular response to hydrogen peroxide GO:0070301 37 0.733
regulation of metal ion transport GO:0010959 120 0.722
cyclic nucleotide mediated signaling GO:0019935 26 0.711
endothelial cell proliferation GO:0001935 65 0.706
regulation of locomotion GO:0040012 329 0.703
regulation of epithelial cell proliferation GO:0050678 113 0.699
positive regulation of large conductance calcium activated potassium channel activity GO:1902608 2 0.699
adaptation of signaling pathway GO:0023058 7 0.699
cytoplasmic transport GO:0016482 379 0.697
erk1 and erk2 cascade GO:0070371 104 0.692
glycerolipid metabolic process GO:0046486 107 0.692
lipid catabolic process GO:0016042 84 0.687
positive regulation of adenylate cyclase activity GO:0045762 12 0.685
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.678
cellular ion homeostasis GO:0006873 168 0.678
negative regulation of transport GO:0051051 176 0.675
immune response activating signal transduction GO:0002757 90 0.675
behavioral defense response GO:0002209 0 0.672
regulation of erk1 and erk2 cascade GO:0070372 99 0.661
activation of protein kinase b activity GO:0032148 14 0.660
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.659
cytosolic calcium ion homeostasis GO:0051480 89 0.657
purine ribonucleotide catabolic process GO:0009154 404 0.656
positive regulation of map kinase activity GO:0043406 80 0.650
lipid metabolic process GO:0006629 381 0.646
calcium ion homeostasis GO:0055074 122 0.640
blood circulation GO:0008015 113 0.639
b cell receptor signaling pathway GO:0050853 18 0.638
regulation of sequestering of calcium ion GO:0051282 41 0.631
cell projection organization GO:0030030 252 0.631
purine ribonucleoside catabolic process GO:0046130 398 0.629
g protein coupled receptor signaling pathway GO:0007186 207 0.626
regulation of camp metabolic process GO:0030814 52 0.622
positive regulation of calcium ion transport GO:0051928 51 0.621
positive regulation of protein phosphorylation GO:0001934 313 0.619
muscle system process GO:0003012 81 0.615
positive regulation of cell matrix adhesion GO:0001954 23 0.615
activation of protein kinase activity GO:0032147 90 0.612
negative regulation of secretion by cell GO:1903531 52 0.612
negative regulation of nucleotide biosynthetic process GO:0030809 11 0.610
behavioral response to ethanol GO:0048149 2 0.607
positive regulation of corticosteroid hormone secretion GO:2000848 5 0.606
regulation of potassium ion transmembrane transport GO:1901379 20 0.597
defense response GO:0006952 315 0.595
cyclic purine nucleotide metabolic process GO:0052652 60 0.595
regulation of camp biosynthetic process GO:0030817 45 0.595
cellular cation homeostasis GO:0030003 163 0.594
negative regulation of lipid metabolic process GO:0045833 38 0.593
purine nucleoside triphosphate metabolic process GO:0009144 412 0.591
ribonucleoside triphosphate catabolic process GO:0009203 391 0.585
cerebellum development GO:0021549 2 0.585
protein modification by small protein conjugation GO:0032446 342 0.583
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.581
nucleoside phosphate catabolic process GO:1901292 412 0.580
hormone secretion GO:0046879 65 0.575
positive regulation of lipid biosynthetic process GO:0046889 22 0.571
cation transport GO:0006812 331 0.570
regulation of hormone secretion GO:0046883 57 0.563
cyclic nucleotide metabolic process GO:0009187 82 0.550
nucleotide biosynthetic process GO:0009165 109 0.549
regulation of glucocorticoid secretion GO:2000849 4 0.548
regulation of wnt protein secretion GO:0061356 1 0.546
cortisol secretion GO:0043400 4 0.544
regulation of tube size GO:0035150 18 0.543
ribose phosphate biosynthetic process GO:0046390 82 0.536
head development GO:0060322 108 0.530
positive regulation of locomotion GO:0040017 186 0.530
regulation of autophagy GO:0010506 52 0.520
positive regulation of cell migration GO:0030335 172 0.518
organ morphogenesis GO:0009887 147 0.509
reactive oxygen species biosynthetic process GO:1903409 4 0.509
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.508
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.507
muscle contraction GO:0006936 73 0.505
cellular calcium ion homeostasis GO:0006874 117 0.505
purine ribonucleoside metabolic process GO:0046128 437 0.504
cellular divalent inorganic cation homeostasis GO:0072503 128 0.503
monovalent inorganic cation transport GO:0015672 128 0.500
purine nucleotide catabolic process GO:0006195 405 0.499
glycosyl compound catabolic process GO:1901658 413 0.498
regulation of ion transport GO:0043269 189 0.493
ribonucleotide biosynthetic process GO:0009260 81 0.493
guanosine containing compound metabolic process GO:1901068 244 0.492
positive regulation of cell adhesion GO:0045785 84 0.488
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.488
cell substrate adhesion GO:0031589 132 0.487
cellular response to endogenous stimulus GO:0071495 336 0.486
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.483
negative regulation of protein kinase b signaling GO:0051898 17 0.481
negative regulation of camp biosynthetic process GO:0030818 9 0.480
divalent inorganic cation homeostasis GO:0072507 136 0.477
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.476
regulation of corticosteroid hormone secretion GO:2000846 5 0.471
cellular response to reactive oxygen species GO:0034614 50 0.468
cellular homeostasis GO:0019725 196 0.468
negative regulation of phosphorus metabolic process GO:0010563 267 0.465
regulation of protein tyrosine kinase activity GO:0061097 36 0.464
regulation of nucleotide catabolic process GO:0030811 205 0.462
phosphatidylinositol metabolic process GO:0046488 53 0.462
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.456
glycerophospholipid biosynthetic process GO:0046474 40 0.456
immune response regulating signaling pathway GO:0002764 97 0.452
neuropeptide signaling pathway GO:0007218 19 0.452
organonitrogen compound biosynthetic process GO:1901566 200 0.450
regulation of protein binding GO:0043393 66 0.448
regulation of intracellular transport GO:0032386 195 0.445
positive regulation of phospholipase c activity GO:0010863 13 0.443
negative regulation of intracellular signal transduction GO:1902532 183 0.442
ruffle organization GO:0031529 18 0.440
enzyme linked receptor protein signaling pathway GO:0007167 303 0.439
second messenger mediated signaling GO:0019932 78 0.438
regulation of cell matrix adhesion GO:0001952 42 0.437
peptidyl tyrosine modification GO:0018212 170 0.436
regulation of behavior GO:0050795 82 0.432
regulation of blood vessel size GO:0050880 18 0.431
glucocorticoid secretion GO:0035933 4 0.429
cytosolic calcium ion transport GO:0060401 48 0.428
biological adhesion GO:0022610 331 0.426
Mouse
purine nucleotide biosynthetic process GO:0006164 84 0.424
purine containing compound biosynthetic process GO:0072522 88 0.422
post embryonic development GO:0009791 2 0.422
male gonad development GO:0008584 23 0.421
antigen receptor mediated signaling pathway GO:0050851 38 0.421
nucleoside triphosphate catabolic process GO:0009143 394 0.416
regulation of cellular component movement GO:0051270 334 0.416
small gtpase mediated signal transduction GO:0007264 78 0.416
positive regulation of epithelial cell proliferation GO:0050679 65 0.411
autophagy GO:0006914 88 0.407
guanosine containing compound catabolic process GO:1901069 239 0.407
activation of mapk activity GO:0000187 45 0.406
intracellular protein transport GO:0006886 270 0.405
regulation of protein secretion GO:0050708 86 0.400
purine ribonucleotide biosynthetic process GO:0009152 79 0.399
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.397
hormone transport GO:0009914 68 0.397
nucleoside phosphate biosynthetic process GO:1901293 109 0.397
regulation of proteolysis GO:0030162 293 0.395
purine containing compound catabolic process GO:0072523 411 0.392
cardiovascular system development GO:0072358 262 0.390
phospholipid biosynthetic process GO:0008654 44 0.388
purine nucleoside catabolic process GO:0006152 398 0.385
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.385
positive regulation of immune response GO:0050778 159 0.384
regulation of phospholipase activity GO:0010517 26 0.379
positive regulation of epidermal growth factor activated receptor activity GO:0045741 8 0.379
androgen metabolic process GO:0008209 9 0.378
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.376
lipid biosynthetic process GO:0008610 177 0.375
regulation of ion homeostasis GO:2000021 73 0.373
central nervous system development GO:0007417 123 0.372
positive regulation of nucleoside metabolic process GO:0045979 186 0.366
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.364
regulation of transmembrane transporter activity GO:0022898 74 0.363
regulation of map kinase activity GO:0043405 108 0.363
epithelial cell proliferation GO:0050673 128 0.363
hormone mediated signaling pathway GO:0009755 22 0.360
regulation of purine nucleotide metabolic process GO:1900542 264 0.358
regulation of cell motility GO:2000145 299 0.357
response to hormone GO:0009725 175 0.355
signal release GO:0023061 70 0.354
behavioral fear response GO:0001662 0 0.354
negative regulation of camp mediated signaling GO:0043951 4 0.352
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.351
cellular response to alkaloid GO:0071312 11 0.346
cellular response to nitrogen compound GO:1901699 144 0.346
positive regulation of cell motility GO:2000147 177 0.346
ovulation cycle process GO:0022602 9 0.345
positive regulation of transport GO:0051050 336 0.342
protein kinase c signaling GO:0070528 17 0.339
regulation of transporter activity GO:0032409 82 0.337
endocrine hormone secretion GO:0060986 13 0.334
protein catabolic process GO:0030163 325 0.333
negative regulation of homeostatic process GO:0032845 59 0.331
regulation of establishment of protein localization GO:0070201 242 0.330
regulation of lipid biosynthetic process GO:0046890 47 0.325
vasoconstriction GO:0042310 11 0.324
response to oxidative stress GO:0006979 121 0.323
system process GO:0003008 349 0.321
Rat
regulation of immune response GO:0050776 201 0.319
regulation of membrane protein ectodomain proteolysis GO:0051043 17 0.318
regulation of gtpase activity GO:0043087 180 0.316
calcium ion transport GO:0006816 147 0.316
regulation of system process GO:0044057 101 0.315
regulation of nucleotide metabolic process GO:0006140 269 0.315
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.314
ras protein signal transduction GO:0007265 73 0.313
regulation of secretion GO:0051046 194 0.310
cellular lipid metabolic process GO:0044255 303 0.309
divalent metal ion transport GO:0070838 152 0.308
estrogen metabolic process GO:0008210 6 0.306
negative regulation of peptide hormone secretion GO:0090278 10 0.305
calcium mediated signaling GO:0019722 44 0.305
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 10 0.304
positive regulation of cytokine production GO:0001819 167 0.303
regulation of cell substrate adhesion GO:0010810 68 0.299
regulation of protein complex assembly GO:0043254 147 0.298
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.295
cation homeostasis GO:0055080 189 0.289
regulation of ion transmembrane transporter activity GO:0032412 72 0.289
negative regulation of purine nucleotide biosynthetic process GO:1900372 11 0.289
regulation of calcium ion transport GO:0051924 79 0.287
metal ion homeostasis GO:0055065 169 0.278
carbohydrate derivative biosynthetic process GO:1901137 207 0.278
sequestering of calcium ion GO:0051208 17 0.276
positive regulation of nucleotide metabolic process GO:0045981 230 0.274
metal ion transport GO:0030001 272 0.273
mapk cascade GO:0000165 288 0.270
negative regulation of cellular catabolic process GO:0031330 83 0.269
cell adhesion GO:0007155 325 0.268
Mouse
response to inorganic substance GO:0010035 127 0.264
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.261
positive regulation of proteolysis GO:0045862 142 0.259
negative regulation of hormone secretion GO:0046888 15 0.259
circulatory system development GO:0072359 262 0.257
ribonucleotide catabolic process GO:0009261 405 0.257
negative regulation of nitric oxide biosynthetic process GO:0045019 5 0.255
regulation of peptide hormone secretion GO:0090276 41 0.253
positive regulation of cyclase activity GO:0031281 13 0.253
regulation of cytokine production GO:0001817 232 0.249
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.247
circulatory system process GO:0003013 113 0.245
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.244
regulation of cytoplasmic transport GO:1903649 149 0.243
peptide hormone secretion GO:0030072 50 0.240
angiogenesis GO:0001525 147 0.238
negative regulation of sequestering of calcium ion GO:0051283 41 0.237
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.237
regulation of wound healing GO:0061041 56 0.237
reactive nitrogen species metabolic process GO:2001057 3 0.236
positive regulation of phospholipase activity GO:0010518 22 0.235
regulation of monooxygenase activity GO:0032768 22 0.235
cgmp metabolic process GO:0046068 19 0.225
negative regulation of camp metabolic process GO:0030815 9 0.223
negative regulation of nucleotide metabolic process GO:0045980 29 0.222
positive regulation of transferase activity GO:0051347 227 0.222
protein ubiquitination GO:0016567 314 0.219
nuclear transport GO:0051169 179 0.216
cellular chemical homeostasis GO:0055082 180 0.215
regulation of membrane potential GO:0042391 95 0.214
Rat
positive regulation of endothelial cell migration GO:0010595 39 0.214
regulation of lyase activity GO:0051339 23 0.213
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.213
positive regulation of nitric oxide synthase activity GO:0051000 7 0.212
positive regulation of cation channel activity GO:2001259 16 0.211
regulation of kinase activity GO:0043549 314 0.210
negative regulation of binding GO:0051100 57 0.208
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.206
regulation of mapk cascade GO:0043408 262 0.206
positive regulation of protein kinase activity GO:0045860 190 0.206
regulation of transferase activity GO:0051338 355 0.202
chemical homeostasis GO:0048878 306 0.197
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.196
male sex differentiation GO:0046661 25 0.195
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.195
regulation of ion transmembrane transport GO:0034765 132 0.192
regulation of endothelial cell migration GO:0010594 67 0.192
regulation of cell differentiation GO:0045595 393 0.191
positive regulation of oxidoreductase activity GO:0051353 26 0.190
negative regulation of protein binding GO:0032091 35 0.190
regulation of lipid metabolic process GO:0019216 96 0.189
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.189
regulation of appetite GO:0032098 1 0.188
response to extracellular stimulus GO:0009991 85 0.188
positive regulation of protein catabolic process GO:0045732 75 0.185
glucose homeostasis GO:0042593 31 0.185
glycerolipid biosynthetic process GO:0045017 51 0.184
protein kinase b signaling GO:0043491 69 0.182
luteinization GO:0001553 2 0.176
secretion GO:0046903 254 0.174
i kappab kinase nf kappab signaling GO:0007249 166 0.173
positive regulation of lipid metabolic process GO:0045834 50 0.173
regulation of protein serine threonine kinase activity GO:0071900 179 0.172
phospholipid metabolic process GO:0006644 99 0.171
response to hydrogen peroxide GO:0042542 40 0.170
peptidyl tyrosine phosphorylation GO:0018108 170 0.169
positive regulation of erbb signaling pathway GO:1901186 11 0.168
activation of adenylate cyclase activity GO:0007190 5 0.168
cation transmembrane transport GO:0098655 238 0.168
response to nutrient levels GO:0031667 81 0.166
positive regulation of cytoplasmic transport GO:1903651 82 0.165
positive regulation of nucleotide catabolic process GO:0030813 185 0.165
regulation of protein catabolic process GO:0042176 155 0.165
divalent inorganic cation transport GO:0072511 158 0.165
regulation of response to wounding GO:1903034 101 0.163
positive regulation of transmembrane transport GO:0034764 41 0.163
steroid hormone secretion GO:0035929 8 0.163
steroid metabolic process GO:0008202 94 0.160
positive regulation of secretion GO:0051047 116 0.159
brain development GO:0007420 97 0.159
regulation of transmembrane transport GO:0034762 139 0.158
regulation of protein kinase b signaling GO:0051896 61 0.157
ribonucleoside triphosphate metabolic process GO:0009199 412 0.156
positive regulation of hydrolase activity GO:0051345 331 0.155
cellular response to oxidative stress GO:0034599 85 0.155
negative regulation of catabolic process GO:0009895 104 0.155
gtp catabolic process GO:0006184 237 0.155
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.155
gtp metabolic process GO:0046039 239 0.152
establishment of protein localization to organelle GO:0072594 172 0.151
reactive oxygen species metabolic process GO:0072593 75 0.150
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.150
vesicle mediated transport GO:0016192 371 0.149
response to oxygen containing compound GO:1901700 369 0.149
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.145
regulation of cortisol secretion GO:0051462 4 0.145
protein import into nucleus GO:0006606 104 0.144
response to lipid GO:0033993 206 0.143
positive regulation of ion transmembrane transport GO:0034767 40 0.142
regulation of oxidoreductase activity GO:0051341 43 0.141
peptidyl serine modification GO:0018209 106 0.140
ovulation cycle GO:0042698 9 0.138
metencephalon development GO:0022037 2 0.138
regulation of protein kinase activity GO:0045859 289 0.137
regulation of secretion by cell GO:1903530 177 0.137
negative regulation of peptide secretion GO:0002792 11 0.136
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 7 0.136
protein localization to organelle GO:0033365 280 0.135
nucleotide catabolic process GO:0009166 408 0.134
cellular response to decreased oxygen levels GO:0036294 51 0.133
peptide secretion GO:0002790 51 0.132
cell projection assembly GO:0030031 126 0.131
defense response to virus GO:0051607 71 0.131
metanephric nephron tubule development GO:0072234 3 0.128
protein localization to nucleus GO:0034504 136 0.127
response to reactive oxygen species GO:0000302 61 0.127
regulation of epithelial cell migration GO:0010632 93 0.127
negative regulation of multicellular organismal process GO:0051241 317 0.124
regulation of homeostatic process GO:0032844 121 0.123
organic hydroxy compound transport GO:0015850 63 0.123
organophosphate catabolic process GO:0046434 430 0.123
positive regulation of endothelial cell proliferation GO:0001938 37 0.123
positive regulation of secretion by cell GO:1903532 108 0.123
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.122
behavior GO:0007610 112 0.121
negative regulation of hippo signaling GO:0035331 6 0.121
cellular response to toxic substance GO:0097237 4 0.120
secretion by cell GO:0032940 226 0.120
neuron differentiation GO:0030182 138 0.120
response to alkaloid GO:0043279 20 0.119
regulation of nervous system development GO:0051960 88 0.118
negative regulation of cyclic nucleotide metabolic process GO:0030800 10 0.118
response to organic cyclic compound GO:0014070 204 0.116
somatic stem cell maintenance GO:0035019 4 0.116
regulation of mitochondrial membrane potential GO:0051881 23 0.114
nervous system development GO:0007399 293 0.113
Rat
negative adaptation of signaling pathway GO:0022401 7 0.112
regulation of neurogenesis GO:0050767 82 0.112
cellular response to catecholamine stimulus GO:0071870 7 0.112
protein oligomerization GO:0051259 173 0.112
hormone metabolic process GO:0042445 61 0.112
determination of adult lifespan GO:0008340 2 0.111
regulation of ras protein signal transduction GO:0046578 155 0.111
response to organonitrogen compound GO:0010243 156 0.111
regulation of anatomical structure size GO:0090066 101 0.111
single organism cellular localization GO:1902580 332 0.109
response to drug GO:0042493 81 0.109
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.109
regulation of protein transport GO:0051223 213 0.109
positive regulation of ras gtpase activity GO:0032320 117 0.108
palate development GO:0060021 13 0.107
cellular response to glucocorticoid stimulus GO:0071385 4 0.106
organophosphate biosynthetic process GO:0090407 163 0.106
positive regulation of immune system process GO:0002684 283 0.105
maintenance of location GO:0051235 112 0.105
protein targeting GO:0006605 187 0.103
regulation of cell cycle process GO:0010564 266 0.103
tissue migration GO:0090130 119 0.103
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.102
positive regulation of cell differentiation GO:0045597 211 0.102
insulin secretion GO:0030073 39 0.102
positive regulation of neurogenesis GO:0050769 49 0.101
positive regulation of mapk cascade GO:0043410 190 0.100
regulation of protein ubiquitination GO:0031396 95 0.100
cellular response to alcohol GO:0097306 29 0.099
positive regulation of homeostatic process GO:0032846 47 0.099
regulation of purine nucleotide catabolic process GO:0033121 205 0.099
negative regulation of cell death GO:0060548 345 0.098
regulation of epithelial cell differentiation involved in kidney development GO:2000696 4 0.097
regulation of fat cell differentiation GO:0045598 23 0.097
regulation of ras gtpase activity GO:0032318 128 0.097
positive regulation of lyase activity GO:0051349 16 0.096
regulation of anatomical structure morphogenesis GO:0022603 286 0.096
cytokinesis GO:0000910 96 0.095
regulation of binding GO:0051098 111 0.093
calcium ion transport into cytosol GO:0060402 48 0.091
response to nitrogen compound GO:1901698 184 0.091
regulation of receptor activity GO:0010469 47 0.091
regulation of reactive oxygen species metabolic process GO:2000377 41 0.091
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.091
epithelium migration GO:0090132 119 0.090
positive regulation of response to wounding GO:1903036 28 0.089
signal transduction by phosphorylation GO:0023014 297 0.089
adrenergic receptor signaling pathway GO:0071875 9 0.089
cgmp biosynthetic process GO:0006182 12 0.087
regulation of cellular component biogenesis GO:0044087 281 0.086
regulation of neurological system process GO:0031644 6 0.086
positive regulation of wound healing GO:0090303 20 0.086
negative regulation of cellular component organization GO:0051129 235 0.085
single organism nuclear import GO:1902593 104 0.085
positive regulation of kinase activity GO:0033674 204 0.085
endocytosis GO:0006897 159 0.083
actin cytoskeleton organization GO:0030036 207 0.082

MPDZ disease predictions

Disease DO term ID Size Probability Func Analog Org