IMP

Process View

Homo sapiens

11 genes annotated in human

positive regulation of epidermal growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of epidermal growth factor receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of epidermal growth factor receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.430
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.330
CHMP4B	chromatin modifying protein 4B	0.214
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.199
MPDZ	multiple PDZ domain protein	0.196
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.136
EGFR	epidermal growth factor receptor	0.130
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.121
DLG1	discs, large homolog 1 (Drosophila)	0.111
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.093
PTK2	PTK2 protein tyrosine kinase 2	0.091
AKNA	AT-hook transcription factor	0.064
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.063
SH3D19	SH3 domain containing 19	0.051
PDCD6IP	programmed cell death 6 interacting protein	0.050
PTPRA	protein tyrosine phosphatase, receptor type, A	0.049
MUC1	mucin 1, cell surface associated	0.043
DNM1	dynamin 1	0.042
ADAM15	ADAM metallopeptidase domain 15	0.042	Human
CCDC6	coiled-coil domain containing 6	0.038
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.035
LRRK2	leucine-rich repeat kinase 2	0.034
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.031
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.030
ARID1A	AT rich interactive domain 1A (SWI-like)	0.028
ADRBK1	adrenergic, beta, receptor kinase 1	0.028
PPP5C	protein phosphatase 5, catalytic subunit	0.027
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.027
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.027
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.026	Fly
MYLK2	myosin light chain kinase 2	0.025
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.024
ARRDC3	arrestin domain containing 3	0.024
ADORA2A	adenosine A2a receptor	0.024
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.024
SRCIN1	SRC kinase signaling inhibitor 1	0.022
APP	amyloid beta (A4) precursor protein	0.021
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.021
CAPRIN2	caprin family member 2	0.021
STC2	stanniocalcin 2	0.020
IGFBP3	insulin-like growth factor binding protein 3	0.019
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.018
PTEN	phosphatase and tensin homolog	0.018
AXIN1	axin 1	0.018
PBRM1	polybromo 1	0.017
ADRB2	adrenergic, beta-2-, receptor, surface	0.017	Human
SP1	Sp1 transcription factor	0.017
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.017
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.017
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.016
MBL2	mannose-binding lectin (protein C) 2, soluble	0.015
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.015	Fly
TBC1D10A	TBC1 domain family, member 10A	0.015
AHNAK	AHNAK nucleoprotein	0.014
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.014
SH3GL2	SH3-domain GRB2-like 2	0.014
DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.014
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.013
GAB1	GRB2-associated binding protein 1	0.013
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.012
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.012
SPRR2A	small proline-rich protein 2A	0.012
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.012
MAPT	microtubule-associated protein tau	0.011
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.011
CCNE1	cyclin E1	0.011
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.011
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.011
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.011
NCOA2	nuclear receptor coactivator 2	0.011
SH3PXD2A	SH3 and PX domains 2A	0.011
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.011
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.011
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.011
GRB10	growth factor receptor-bound protein 10	0.010
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.010
CAV1	caveolin 1, caveolae protein, 22kDa	0.010