IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of phosphatidylinositol biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of phosphatidylinositol biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of phosphatidylinositol biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
MPDZ	multiple PDZ domain protein	1.000
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1.000
SPAG9	sperm associated antigen 9	0.985
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.976
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.949
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.724
ARRDC3	arrestin domain containing 3	0.664
SSTR3	somatostatin receptor 3	0.550
TBC1D10A	TBC1 domain family, member 10A	0.449
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.351
PTEN	phosphatase and tensin homolog	0.275
BAI1	brain-specific angiogenesis inhibitor 1	0.192
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.119
ADAM15	ADAM metallopeptidase domain 15	0.109
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.090
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.082
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.078
EZR	ezrin	0.076
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	0.070	Human
GPR6	G protein-coupled receptor 6	0.062
OR2H1	olfactory receptor, family 2, subfamily H, member 1	0.062
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.056
GHRHR	growth hormone releasing hormone receptor	0.054
TSHR	thyroid stimulating hormone receptor	0.053
CCK	cholecystokinin	0.052
ADRB2	adrenergic, beta-2-, receptor, surface	0.048	Human
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.047	Human
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.045
ARFIP2	ADP-ribosylation factor interacting protein 2	0.045
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.044
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.043
CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.043
THPO	thrombopoietin	0.039
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.039
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.038
SMCP	sperm mitochondria-associated cysteine-rich protein	0.034
AKAP12	A kinase (PRKA) anchor protein 12	0.033
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.032
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.031
AQP7	aquaporin 7	0.031
ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	0.031
DSCAML1	Down syndrome cell adhesion molecule like 1	0.031
AFF2	AF4/FMR2 family, member 2	0.030
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.030
COPG2	coatomer protein complex, subunit gamma 2	0.030
SRCIN1	SRC kinase signaling inhibitor 1	0.027
GRM5	glutamate receptor, metabotropic 5	0.027
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	0.027
KRT33B	keratin 33B	0.027
SMR3A	submaxillary gland androgen regulated protein 3A	0.026
ODF1	outer dense fiber of sperm tails 1	0.026
DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.026
CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	0.025
ADRA2B	adrenergic, alpha-2B-, receptor	0.025
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.025
AMOTL2	angiomotin like 2	0.024
PTPRR	protein tyrosine phosphatase, receptor type, R	0.024
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.023
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.023
RACGAP1	Rac GTPase activating protein 1	0.023
VIPR2	vasoactive intestinal peptide receptor 2	0.023
CCR3	chemokine (C-C motif) receptor 3	0.023
OPRK1	opioid receptor, kappa 1	0.023
SLC14A2	solute carrier family 14 (urea transporter), member 2	0.022
SPTB	spectrin, beta, erythrocytic	0.022
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.022
NTSR1	neurotensin receptor 1 (high affinity)	0.022
NELL1	NEL-like 1 (chicken)	0.022
PTPRA	protein tyrosine phosphatase, receptor type, A	0.022
SLC18A1	solute carrier family 18 (vesicular monoamine), member 1	0.022
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.022
ADRBK1	adrenergic, beta, receptor kinase 1	0.022
GLRA1	glycine receptor, alpha 1	0.021
TNP2	transition protein 2 (during histone to protamine replacement)	0.021
AMHR2	anti-Mullerian hormone receptor, type II	0.021
POU4F2	POU class 4 homeobox 2	0.021
CHRNB4	cholinergic receptor, nicotinic, beta 4	0.021
CDV3	CDV3 homolog (mouse)	0.021
ADRA1A	adrenergic, alpha-1A-, receptor	0.021
CRP	C-reactive protein, pentraxin-related	0.019
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.019
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.019
DRD1	dopamine receptor D1	0.019	Human
MUC1	mucin 1, cell surface associated	0.019
PDYN	prodynorphin	0.019
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	0.019
MUSK	muscle, skeletal, receptor tyrosine kinase	0.019
GRM2	glutamate receptor, metabotropic 2	0.018
NXPH3	neurexophilin 3	0.018
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.018
TRH	thyrotropin-releasing hormone	0.018
CALCR	calcitonin receptor	0.018
APOC3	apolipoprotein C-III	0.018
SCTR	secretin receptor	0.018
RELN	reelin	0.018
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.018
TBX5	T-box 5	0.018
CCKBR	cholecystokinin B receptor	0.018
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.018
PLA2G1B	phospholipase A2, group IB (pancreas)	0.018
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.017
GCM1	glial cells missing homolog 1 (Drosophila)	0.017
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.017
YAP1	Yes-associated protein 1	0.017
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.017
ADRA1D	adrenergic, alpha-1D-, receptor	0.017
LILRA4	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4	0.016
FEZF2	FEZ family zinc finger 2	0.016
CTRC	chymotrypsin C (caldecrin)	0.016
RHO	rhodopsin	0.016
RAB8A	RAB8A, member RAS oncogene family	0.016
SCN1B	sodium channel, voltage-gated, type I, beta	0.016
KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	0.016
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.016
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.016
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.016
GRM7	glutamate receptor, metabotropic 7	0.016
TBR1	T-box, brain, 1	0.016
GABRA6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	0.016
F2RL2	coagulation factor II (thrombin) receptor-like 2	0.016
EMX2	empty spiracles homeobox 2	0.016
IL6R	interleukin 6 receptor	0.016
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.016
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.016
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.016
KIF23	kinesin family member 23	0.015
NOS2	nitric oxide synthase 2, inducible	0.015
DLG4	discs, large homolog 4 (Drosophila)	0.015
CPLX2	complexin 2	0.015
PRC1	protein regulator of cytokinesis 1	0.015
PADI4	peptidyl arginine deiminase, type IV	0.015
GIF	gastric intrinsic factor (vitamin B synthesis)	0.015
DRD2	dopamine receptor D2	0.015
MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	0.015
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.015
RIMS4	regulating synaptic membrane exocytosis 4	0.014
POU3F1	POU class 3 homeobox 1	0.014
OPRD1	opioid receptor, delta 1	0.014
TLX3	T-cell leukemia homeobox 3	0.014
CRHR2	corticotropin releasing hormone receptor 2	0.014
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.014
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.014
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	0.014	Human
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.014
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.014
OPRL1	opiate receptor-like 1	0.014
GPC5	glypican 5	0.014
OPRM1	opioid receptor, mu 1	0.014
MEX3B	mex-3 homolog B (C. elegans)	0.014
AVPR1B	arginine vasopressin receptor 1B	0.014
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.014
CNR2	cannabinoid receptor 2 (macrophage)	0.014
CAMK1G	calcium/calmodulin-dependent protein kinase IG	0.014
TFF2	trefoil factor 2	0.013
HRH3	histamine receptor H3	0.013
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.013
TMOD3	tropomodulin 3 (ubiquitous)	0.013
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.013
CXCR1	chemokine (C-X-C motif) receptor 1	0.013
DLGAP3	discs, large (Drosophila) homolog-associated protein 3	0.013
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.013
NPY2R	neuropeptide Y receptor Y2	0.013
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.013
MAS1	MAS1 oncogene	0.013
KRT9	keratin 9	0.013
P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3	0.013
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.013	Human
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.013
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.013
FGF18	fibroblast growth factor 18	0.013
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.013
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.013
GFRA2	GDNF family receptor alpha 2	0.013
ACCN1	amiloride-sensitive cation channel 1, neuronal	0.013
PNMT	phenylethanolamine N-methyltransferase	0.013
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.013
PYY	peptide YY	0.013
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.012
AMOT	angiomotin	0.012
ATP10A	ATPase, class V, type 10A	0.012
GPR26	G protein-coupled receptor 26	0.012
LNX1	ligand of numb-protein X 1	0.012
DGKQ	diacylglycerol kinase, theta 110kDa	0.012
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.012
GFRA4	GDNF family receptor alpha 4	0.012
PRDM8	PR domain containing 8	0.012
ACRV1	acrosomal vesicle protein 1	0.012
OCA2	oculocutaneous albinism II	0.012
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.012
NEUROG1	neurogenin 1	0.012
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.012
CNNM1	cyclin M1	0.012
WNT8B	wingless-type MMTV integration site family, member 8B	0.012
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.012
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.012
EMX1	empty spiracles homeobox 1	0.012
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.012
EFNB3	ephrin-B3	0.012
NTSR2	neurotensin receptor 2	0.012
HBZ	hemoglobin, zeta	0.012
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.012
NPY1R	neuropeptide Y receptor Y1	0.012
GYPA	glycophorin A (MNS blood group)	0.012
LGI1	leucine-rich, glioma inactivated 1	0.012
IRS4	insulin receptor substrate 4	0.012
TACR3	tachykinin receptor 3	0.012
UNC13A	unc-13 homolog A (C. elegans)	0.012
HBE1	hemoglobin, epsilon 1	0.012
TREH	trehalase (brush-border membrane glycoprotein)	0.012
GP5	glycoprotein V (platelet)	0.012
GH2	growth hormone 2	0.012
FOXI1	forkhead box I1	0.011
AANAT	aralkylamine N-acetyltransferase	0.011
SOAT2	sterol O-acyltransferase 2	0.011
GYPE	glycophorin E (MNS blood group)	0.011
KRT2	keratin 2	0.011
RASL10A	RAS-like, family 10, member A	0.011
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.011
PDE1B	phosphodiesterase 1B, calmodulin-dependent	0.011
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B	0.011
CHRNB3	cholinergic receptor, nicotinic, beta 3	0.011
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.011
CHRND	cholinergic receptor, nicotinic, delta	0.011
ITGAD	integrin, alpha D	0.011
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A	0.011	Human
IL19	interleukin 19	0.011
FRMPD4	FERM and PDZ domain containing 4	0.011
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.011
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.011
IL5RA	interleukin 5 receptor, alpha	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
DCC	deleted in colorectal carcinoma	0.011
NTF3	neurotrophin 3	0.011
CADM3	cell adhesion molecule 3	0.011
GLP1R	glucagon-like peptide 1 receptor	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
FXYD7	FXYD domain containing ion transport regulator 7	0.011
ADAM2	ADAM metallopeptidase domain 2	0.011
PNLIPRP1	pancreatic lipase-related protein 1	0.011
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.011
P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	0.011
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.011
WNT1	wingless-type MMTV integration site family, member 1	0.011
RAI2	retinoic acid induced 2	0.011
ZNF132	zinc finger protein 132	0.011
CNTN2	contactin 2 (axonal)	0.010
CHD5	chromodomain helicase DNA binding protein 5	0.010
BFSP2	beaded filament structural protein 2, phakinin	0.010
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.010
LPAR4	lysophosphatidic acid receptor 4	0.010
AGXT	alanine-glyoxylate aminotransferase	0.010
F2RL3	coagulation factor II (thrombin) receptor-like 3	0.010
GALR3	galanin receptor 3	0.010
GPR27	G protein-coupled receptor 27	0.010
PCSK2	proprotein convertase subtilisin/kexin type 2	0.010
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.010
TUB	tubby homolog (mouse)	0.010
CCL11	chemokine (C-C motif) ligand 11	0.010
SPRR2A	small proline-rich protein 2A	0.010
BCAR1	breast cancer anti-estrogen resistance 1	0.010
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.010
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.010
PNOC	prepronociceptin	0.010
CYTH1	cytohesin 1	0.010
KCNT1	potassium channel, subfamily T, member 1	0.010
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.010