|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.999
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.999
|
|
|
|
monocyte activation
|
GO:0042117 |
3 |
0.995
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.991
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.987
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.982
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.977
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.970
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.966
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.952
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.947
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.944
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.943
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.935
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.932
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.916
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.887
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.886
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.886
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.874
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.844
|
|
|
|
keratinocyte migration
|
GO:0051546 |
6 |
0.843
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.834
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.820
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.806
|
|
|
|
pma inducible membrane protein ectodomain proteolysis
|
GO:0051088 |
3 |
0.805
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.804
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.798
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.795
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.789
|
|
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.784
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.776
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.754
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.739
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.731
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.731
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.721
|
Worm |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.711
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.708
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.695
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.692
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.687
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.670
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.664
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.649
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.649
|
Fly |
|
|
t cell chemotaxis
|
GO:0010818 |
10 |
0.649
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.646
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.643
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.641
|
Human |
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.617
|
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.613
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.613
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.610
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.599
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.596
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.590
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.590
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.570
|
Fly |
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.566
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.564
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.559
|
Fly |
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.556
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.555
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.550
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.543
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.541
|
Fly |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.534
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.527
|
|
|
|
positive regulation of cell adhesion mediated by integrin
|
GO:0033630 |
9 |
0.527
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.527
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.526
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.519
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.514
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.510
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.504
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.491
|
Worm |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.490
|
Human |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.483
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.483
|
Fly |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.482
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.477
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.471
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.469
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.458
|
Fly |
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.454
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.453
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.448
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.444
|
Fly |
|
|
response to high density lipoprotein particle
|
GO:0055099 |
1 |
0.438
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.432
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.425
|
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
8 |
0.421
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.420
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.418
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.416
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.412
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.410
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.404
|
Human |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.400
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.400
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.392
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.391
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.389
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.383
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.382
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.382
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.376
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.375
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.374
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.367
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.366
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.360
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.357
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.353
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.350
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.345
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.341
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.334
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.333
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.332
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.331
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.327
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.327
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.325
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.322
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
1 |
0.322
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.321
|
|
|
|
positive regulation of macrophage fusion
|
GO:0034241 |
1 |
0.315
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.312
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.308
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.308
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.307
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.305
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.302
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.294
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.289
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.287
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.287
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.285
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.282
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.279
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.278
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.270
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.269
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.266
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.264
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.264
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.262
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.251
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.246
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.245
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.244
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.243
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.242
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.240
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.239
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.236
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.235
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.234
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.234
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.231
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.231
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.231
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.228
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.226
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.226
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.225
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.224
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.221
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.221
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.220
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.215
|
|
|
|
epiboly
|
GO:0090504 |
9 |
0.214
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.207
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.207
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.207
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.200
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.199
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.197
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.194
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.193
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.193
|
Mouse Worm Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.192
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.188
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.187
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.187
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.186
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.185
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.181
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.180
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.180
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.179
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.175
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.174
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.173
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.170
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.170
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.168
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.166
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.166
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.165
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.165
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.163
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.163
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.161
|
Fly |
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.161
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.160
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.159
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.159
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.158
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.158
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.158
|
|
|
|
growth
|
GO:0040007 |
202 |
0.157
|
Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.157
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.157
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.157
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.154
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.154
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.153
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.150
|
Mouse Worm Fly |
|
|
skin development
|
GO:0043588 |
76 |
0.147
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.145
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.143
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.142
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.139
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.137
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.135
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.133
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.132
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.131
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.130
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.129
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.129
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.128
|
Mouse Worm Fly |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.127
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.126
|
Worm Fly |
|
|
positive regulation of erbb signaling pathway
|
GO:1901186 |
11 |
0.126
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.125
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.121
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.118
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.118
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.118
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.116
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.115
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.111
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.107
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.107
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.107
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.106
|
|
|
|
syncytium formation
|
GO:0006949 |
4 |
0.106
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.106
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.103
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.103
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.102
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.098
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.098
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.097
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.096
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.094
|
Worm |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.094
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.092
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.091
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.090
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.088
|
Fly |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.086
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.085
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.084
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.083
|
|
|
|
cell cell adhesion mediated by integrin
|
GO:0033631 |
8 |
0.082
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.082
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.081
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.079
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.078
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.077
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.077
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.077
|
|
|
|
hydrogen peroxide mediated programmed cell death
|
GO:0010421 |
4 |
0.076
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.076
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.075
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.075
|
|
|
|
neuron projection extension involved in neuron projection guidance
|
GO:1902284 |
5 |
0.074
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.074
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.073
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.073
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.073
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.072
|
|
|
|
response to lipoprotein particle
|
GO:0055094 |
5 |
0.069
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.068
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.067
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.065
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.063
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.062
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.062
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.060
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.060
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.058
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.058
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.057
|
Mouse Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.057
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.055
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.055
|
|
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.054
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.054
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.054
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.054
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.053
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.053
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.052
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.052
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.051
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.051
|
Fly |
|
|
actin filament reorganization
|
GO:0090527 |
1 |
0.051
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.051
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.051
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.050
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.050
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.049
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.049
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.048
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.047
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.047
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.047
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.047
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.047
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.046
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.046
|
Mouse Worm Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.046
|
Worm Fly |
|
|
head development
|
GO:0060322 |
108 |
0.046
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
9 |
0.045
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.045
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.045
|
|
|
|
positive regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000096 |
2 |
0.045
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.044
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.043
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.043
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.042
|
Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.041
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.040
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.040
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.040
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
5 |
0.039
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.039
|
|
|
|
neuron migration
|
GO:0001764 |
11 |
0.039
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.039
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.038
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.038
|
|
|
|
positive regulation of lamellipodium organization
|
GO:1902745 |
12 |
0.038
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.038
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.037
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.037
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.037
|
Fly |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.037
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.036
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.036
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.036
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.036
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.036
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.036
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.035
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.035
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.035
|
Worm |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.035
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.034
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.034
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.034
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.033
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.033
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.033
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.033
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.033
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.032
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
3 |
0.032
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.032
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.032
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.032
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.031
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
2 |
0.031
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.031
|
Fly |
|
|
thymus development
|
GO:0048538 |
3 |
0.031
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.030
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.030
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.030
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.030
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.030
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.029
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.029
|
|
|
|
regulation of interferon gamma secretion
|
GO:1902713 |
2 |
0.029
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.028
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.028
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.028
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.028
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.028
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.028
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.027
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.027
|
|
|
|
regulation of receptor binding
|
GO:1900120 |
8 |
0.027
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.027
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.027
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.027
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.027
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.026
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.026
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.026
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
14 |
0.026
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.026
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.025
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.025
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.025
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.025
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.025
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.025
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.025
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.025
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.025
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.025
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.024
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.024
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.024
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.024
|
|
|
|
intraciliary transport
|
GO:0042073 |
7 |
0.024
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.024
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.024
|
Worm |
|
|
neuron development
|
GO:0048666 |
113 |
0.024
|
Mouse Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.023
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.023
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.023
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.023
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.023
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.023
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.023
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.023
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.023
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.023
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.023
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.023
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.023
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.022
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.022
|
Worm Fly |
|
|
response to fungus
|
GO:0009620 |
4 |
0.022
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.022
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.022
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.022
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.022
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.021
|
|
|
|
programmed cell death in response to reactive oxygen species
|
GO:0097468 |
4 |
0.021
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.021
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.021
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.021
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.021
|
|
|
|
negative regulation of actin filament bundle assembly
|
GO:0032232 |
9 |
0.021
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.021
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.021
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.020
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.020
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.020
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.020
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.020
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.020
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.020
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.020
|
Mouse |
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.020
|
Fly |
|
|
cortical cytoskeleton organization
|
GO:0030865 |
9 |
0.020
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.019
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.019
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.019
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.019
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.019
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
|
|
|
response to epinephrine
|
GO:0071871 |
2 |
0.019
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.018
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.018
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.018
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.018
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.018
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.018
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.018
|
Mouse Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.018
|
|
