|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.995
|
|
|
|
positive regulation of myoblast fusion
|
GO:1901741 |
1 |
0.981
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.945
|
|
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.939
|
Mouse |
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.928
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
5 |
0.911
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.847
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.828
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.806
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.792
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
2 |
0.790
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.779
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.775
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.758
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.758
|
Fly |
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.733
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.718
|
Mouse Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.711
|
Human Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.709
|
Mouse Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.665
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.647
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.627
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.597
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.593
|
Human |
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.579
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.559
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.550
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
3 |
0.550
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
3 |
0.544
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
5 |
0.531
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.531
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.508
|
Fly |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.505
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.499
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.496
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.494
|
Mouse Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.490
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.484
|
Human Rat |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.472
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.466
|
Human |
|
|
exocytosis
|
GO:0006887 |
71 |
0.465
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.463
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.461
|
Fly |
|
|
chemokine production
|
GO:0032602 |
32 |
0.444
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.444
|
Human Mouse Fly |
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.426
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.422
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.404
|
Mouse |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.404
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.393
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.393
|
Fly |
|
|
t helper 1 cell differentiation
|
GO:0045063 |
1 |
0.385
|
Mouse |
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.382
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
3 |
0.371
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.360
|
Mouse Fly |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
5 |
0.359
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.352
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.351
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.349
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.335
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.331
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.329
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
5 |
0.323
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.322
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.315
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.312
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.303
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.302
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.299
|
Human Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.296
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.295
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.295
|
Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.293
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.289
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.285
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.283
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.277
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.269
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.269
|
Fly |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.267
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.253
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.250
|
Fly |
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
8 |
0.249
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.244
|
Mouse |
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.241
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.236
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.234
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.234
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.233
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.230
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.229
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.226
|
Mouse |
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.223
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.221
|
Human Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.217
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.212
|
Human Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.212
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.210
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.208
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.207
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.206
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.198
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
10 |
0.197
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.195
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.193
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.190
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
1 |
0.183
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.182
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.182
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.178
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.174
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.172
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.169
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.169
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.168
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.165
|
Fly |
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.161
|
Mouse Fly |
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
2 |
0.161
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.160
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.158
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.153
|
Fly |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.151
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.151
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.151
|
Mouse |
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.144
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.143
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.141
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.140
|
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
17 |
0.139
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.137
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.137
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.137
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.136
|
Mouse Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.133
|
Mouse Fly |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.132
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.132
|
Fly |
|
|
lipid localization
|
GO:0010876 |
106 |
0.131
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.130
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.130
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.129
|
Human |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.128
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.128
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.127
|
Fly |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
5 |
0.127
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.125
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.123
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.121
|
Fly |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.121
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.119
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.119
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.118
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.118
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.117
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.116
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.116
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.115
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.115
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.114
|
Human |
|
|
interferon beta production
|
GO:0032608 |
23 |
0.114
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.113
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.111
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.110
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.108
|
Human Rat Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.107
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.106
|
Mouse |
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.106
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.105
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.104
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.103
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.102
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
11 |
0.098
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.097
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.094
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.093
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.093
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.091
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.091
|
Human |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.090
|
Mouse |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.090
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.090
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.088
|
Mouse Fly |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.088
|
Human |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.088
|
Fly |
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.087
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.087
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.087
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.087
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.087
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.087
|
Fly |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.087
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.086
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.084
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.083
|
Human |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.082
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.081
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.081
|
Human |
|
|
b cell activation
|
GO:0042113 |
33 |
0.080
|
Mouse |
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.080
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.080
|
Human Rat |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.077
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.077
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
2 |
0.076
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.076
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.075
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
5 |
0.075
|
Mouse |
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
1 |
0.075
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.075
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.074
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.074
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.074
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.073
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.072
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.071
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.070
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.070
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.069
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.068
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.068
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.067
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.066
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.065
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.065
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.065
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.065
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.065
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.064
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
6 |
0.063
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.063
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.063
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.063
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.063
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.062
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.062
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.061
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.060
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.060
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.060
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.060
|
Fly |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.059
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.059
|
Mouse Fly |
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
7 |
0.059
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.057
|
Human Mouse Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.057
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.057
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.057
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.057
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.056
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.056
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.056
|
Human |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.055
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.055
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.055
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.054
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.054
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.054
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.054
|
Human |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
11 |
0.053
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.051
|
|
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
4 |
0.051
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.051
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.051
|
Mouse |
|
|
macrophage activation
|
GO:0042116 |
12 |
0.051
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.051
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.051
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.051
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.051
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.050
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.050
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.050
|
Human |
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.049
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.049
|
Fly |
|
|
response to dsrna
|
GO:0043331 |
25 |
0.049
|
|
|
|
cellular response to dsrna
|
GO:0071359 |
19 |
0.048
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.048
|
Fly |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.048
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.048
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.047
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.047
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.047
|
Human |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.046
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.046
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.046
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.046
|
Mouse |
|
|
head development
|
GO:0060322 |
108 |
0.046
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.046
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.045
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.045
|
Mouse |
|
|
lipid transport
|
GO:0006869 |
90 |
0.045
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.045
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.045
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.044
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.044
|
Human Rat Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.044
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.043
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.043
|
Mouse |
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.043
|
Mouse |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.043
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.042
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.042
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.042
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.041
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.041
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
8 |
0.041
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.041
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.040
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.040
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.040
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.040
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.040
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.040
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.040
|
Human |
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.040
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.040
|
Human |
|
|
mast cell mediated immunity
|
GO:0002448 |
5 |
0.039
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.039
|
Mouse |
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.039
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.039
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.039
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.038
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.038
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.038
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.038
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.038
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.038
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.037
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.037
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.037
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.037
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.037
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.037
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.037
|
Fly |
|
|
positive regulation of t helper 2 cell differentiation
|
GO:0045630 |
1 |
0.037
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.037
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.037
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.036
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.036
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.036
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.036
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.036
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.036
|
|
|
|
memory
|
GO:0007613 |
3 |
0.036
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.036
|
Mouse |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.036
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.035
|
Worm Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.035
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.035
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.035
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.034
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.034
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.034
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.034
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.034
|
|
|
|
growth
|
GO:0040007 |
202 |
0.034
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.034
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.034
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.034
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.033
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.033
|
Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.033
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.033
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.033
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.033
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.033
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.032
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.032
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.032
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.032
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.032
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.031
|
Fly |
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.031
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.031
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.031
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.031
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.031
|
Fly |
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.031
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.030
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.030
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.030
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.030
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.030
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.030
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.030
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.030
|
Fly |
|
|
regulation of viral genome replication
|
GO:0045069 |
48 |
0.030
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.030
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.030
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.029
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.029
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.029
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.029
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.029
|
Mouse |
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
3 |
0.029
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
10 |
0.028
|
Mouse |
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.028
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.027
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.027
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.027
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.027
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.027
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
6 |
0.027
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.027
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.026
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.026
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.026
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.026
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.026
|
Fly |
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.026
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.026
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.026
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.026
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.026
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.026
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.025
|
Rat |
|
|
chemokine metabolic process
|
GO:0050755 |
4 |
0.025
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.025
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.025
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.025
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.025
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.025
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.025
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.025
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.025
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
4 |
0.025
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.025
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.024
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
3 |
0.024
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.024
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.024
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.024
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.024
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.024
|
|
|
|
system process
|
GO:0003008 |
349 |
0.024
|
Fly |
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.024
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.024
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
6 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.023
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.023
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.023
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.023
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.023
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.023
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.023
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.023
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.023
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.023
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.023
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.023
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.023
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.023
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.023
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.023
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.022
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.022
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.022
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.022
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.022
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.022
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.022
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.022
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.022
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.022
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.022
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.022
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.022
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.022
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.021
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.021
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.021
|
Fly |
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.021
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.021
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.021
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
8 |
0.021
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.020
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.020
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.020
|
|
