IMP
Process View
chemokine metabolic process
The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "chemokine metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.972 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.926 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.840 | ||
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.733 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.709 | ||
| TLR4 | toll-like receptor 4 | 0.645 | ||
| IL8 | interleukin 8 | 0.618 | ||
| IL4R | interleukin 4 receptor | 0.548 | ||
| TLR2 | toll-like receptor 2 | 0.421 | ||
| IL1RAP | interleukin 1 receptor accessory protein | 0.364 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.230 | ||
| IL1B | interleukin 1, beta | 0.150 | Mouse | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.149 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.147 | ||
| IL6R | interleukin 6 receptor | 0.135 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.114 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.099 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.098 | ||
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.090 | ||
| SPOP | speckle-type POZ protein | 0.090 | ||
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.088 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.081 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.075 | ||
| ENO2 | enolase 2 (gamma, neuronal) | 0.072 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.072 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.062 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.060 | ||
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.056 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.056 | ||
| IRF7 | interferon regulatory factor 7 | 0.054 | ||
| CD83 | CD83 molecule | 0.044 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.041 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.039 | Mouse | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.035 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.031 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.030 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.028 | ||
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.028 | ||
| MPO | myeloperoxidase | 0.026 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.025 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.023 | ||
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.023 | ||
| IL13 | interleukin 13 | 0.023 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.023 | ||
| AZU1 | azurocidin 1 | 0.022 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.020 | ||
| STAP2 | signal transducing adaptor family member 2 | 0.017 | ||
| BCL2A1 | BCL2-related protein A1 | 0.016 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.016 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.016 | ||
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.016 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.015 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.015 | ||
| TRIM14 | tripartite motif containing 14 | 0.015 | ||
| PLAU | plasminogen activator, urokinase | 0.014 | ||
| HRH1 | histamine receptor H1 | 0.013 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.013 | ||
| SOD2 | superoxide dismutase 2, mitochondrial | 0.012 | ||
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.012 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.011 | ||
| CLEC4G | C-type lectin domain family 4, member G | 0.011 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.011 | ||
| IL1R2 | interleukin 1 receptor, type II | 0.011 | ||
| RNASE3 | ribonuclease, RNase A family, 3 | 0.011 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.011 | ||
| C11orf2 | chromosome 11 open reading frame 2 | 0.010 | ||
| DOCK8 | dedicator of cytokinesis 8 | 0.010 | ||
| PI3 | peptidase inhibitor 3, skin-derived | 0.010 | ||
| IER3 | immediate early response 3 | 0.010 |