IMP
Process View
positive regulation of alpha beta t cell activation
Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of alpha beta t cell activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| LCK | lymphocyte-specific protein tyrosine kinase | 0.985 | ||
| LAT | linker for activation of T cells | 0.878 | ||
| CD247 | CD247 molecule | 0.820 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.796 | Mouse | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.787 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.641 | Human | |
| LIN9 | lin-9 homolog (C. elegans) | 0.486 | ||
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.440 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.364 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.316 | Mouse | |
| TRAF1 | TNF receptor-associated factor 1 | 0.303 | ||
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.250 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.216 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.212 | Mouse | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.209 | ||
| SYK | spleen tyrosine kinase | 0.163 | Mouse | |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.147 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.146 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.131 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.125 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.116 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.103 | Human | |
| IL4R | interleukin 4 receptor | 0.100 | Mouse | |
| RXRA | retinoid X receptor, alpha | 0.095 | ||
| IL4 | interleukin 4 | 0.095 | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.088 | Mouse | |
| IDE | insulin-degrading enzyme | 0.085 | ||
| IL23A | interleukin 23, alpha subunit p19 | 0.077 | ||
| IL2RB | interleukin 2 receptor, beta | 0.072 | ||
| CD2 | CD2 molecule | 0.068 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.063 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.057 | Human | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.057 | Human | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.053 | Human | |
| GRAP2 | GRB2-related adaptor protein 2 | 0.051 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.050 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.045 | ||
| MED25 | mediator complex subunit 25 | 0.045 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.045 | Human | |
| IL1B | interleukin 1, beta | 0.045 | ||
| SH2D2A | SH2 domain containing 2A | 0.045 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.045 | Human Mouse | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.043 | ||
| IL7R | interleukin 7 receptor | 0.040 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.040 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.039 | Human | |
| IL6R | interleukin 6 receptor | 0.038 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.037 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.037 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.037 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.035 | ||
| LIN54 | lin-54 homolog (C. elegans) | 0.034 | ||
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.033 | ||
| CD48 | CD48 molecule | 0.032 | ||
| IL10 | interleukin 10 | 0.031 | ||
| IFNG | interferon, gamma | 0.028 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.027 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.027 | ||
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | 0.027 | ||
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.025 | ||
| CCR4 | chemokine (C-C motif) receptor 4 | 0.025 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.024 | Mouse | |
| IL21R | interleukin 21 receptor | 0.024 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.023 | Human | |
| ENG | endoglin | 0.022 | ||
| IL8 | interleukin 8 | 0.022 | ||
| TNF | tumor necrosis factor | 0.022 | ||
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.021 | ||
| SELE | selectin E | 0.020 | ||
| CSNK1G1 | casein kinase 1, gamma 1 | 0.019 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.019 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.016 | Human | |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.016 | ||
| CD83 | CD83 molecule | 0.015 | Mouse | |
| IRF4 | interferon regulatory factor 4 | 0.014 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.014 | ||
| CPD | carboxypeptidase D | 0.013 | ||
| IL2RA | interleukin 2 receptor, alpha | 0.013 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.013 | ||
| RGS16 | regulator of G-protein signaling 16 | 0.012 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.012 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.012 | Human | |
| SLA | Src-like-adaptor | 0.012 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.011 | ||
| UNC119 | unc-119 homolog (C. elegans) | 0.011 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.011 | ||
| RARA | retinoic acid receptor, alpha | 0.011 | ||
| CD274 | CD274 molecule | 0.011 | ||
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.011 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.011 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.010 | ||
| PRKCQ | protein kinase C, theta | 0.010 | Mouse |