|
|
mrna 3 end processing
|
GO:0031124 |
24 |
0.992
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.989
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.969
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.956
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.893
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.892
|
|
|
|
histone mrna 3 end processing
|
GO:0006398 |
3 |
0.864
|
|
|
|
rna polyadenylation
|
GO:0043631 |
14 |
0.840
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.828
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.777
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.697
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.611
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.585
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.548
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.518
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.503
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.475
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.467
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.458
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.458
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.443
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.429
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.410
|
|
|
|
histone mrna metabolic process
|
GO:0008334 |
13 |
0.387
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.387
|
Fly |
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.382
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.352
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.352
|
|
|
|
mrna polyadenylation
|
GO:0006378 |
12 |
0.351
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.349
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.343
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.338
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.337
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.312
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.311
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.306
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.299
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.297
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.294
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.290
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.285
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.281
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.276
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.271
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.259
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.253
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.234
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.229
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.220
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.215
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.215
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.214
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.213
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.212
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.212
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.208
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.208
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.206
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.201
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.195
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.194
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.191
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.190
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.189
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.185
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.178
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.175
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.171
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.169
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.168
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.165
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.165
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.165
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.162
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.160
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.159
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.157
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.157
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.157
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.156
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.155
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.152
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.149
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.146
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.144
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.144
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.143
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.141
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.139
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.139
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
13 |
0.138
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.136
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.136
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.133
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.132
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.131
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.131
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.125
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.125
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.124
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.123
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.122
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.119
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.118
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.116
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.116
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.114
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.114
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.114
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.114
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.113
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.113
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.112
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.111
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.111
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.109
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.108
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.108
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.108
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.105
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.104
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.103
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.102
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.101
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.101
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.100
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.099
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.097
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.096
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.096
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.096
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.095
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.095
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.094
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.094
|
Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.093
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.093
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.093
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.092
|
|
|
|
positive regulation of signal transduction by p53 class mediator
|
GO:1901798 |
10 |
0.092
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.091
|
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.088
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.088
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.088
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.088
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.087
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.087
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.086
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.084
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.084
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.083
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.082
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.082
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.081
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.081
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.081
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.079
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902255 |
2 |
0.077
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.076
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.076
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.076
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.075
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.074
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.074
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.073
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.072
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.072
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.072
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.072
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.070
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.070
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.069
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.069
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.069
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.068
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.068
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.068
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.068
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.067
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.067
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.066
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.066
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.066
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.066
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.066
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.065
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.065
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.065
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.065
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.065
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.064
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.063
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.063
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.063
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.063
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.062
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.062
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.061
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.061
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.061
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.059
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.059
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.059
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.058
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.058
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.057
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.056
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.056
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.056
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
2 |
0.056
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.055
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
5 |
0.055
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.055
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.055
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.054
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.053
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.053
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.053
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.053
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.052
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.052
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.052
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.051
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.051
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.051
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.050
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.050
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.050
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.049
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.048
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.048
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.048
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.047
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.047
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.047
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.047
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.047
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.046
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.046
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.045
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.045
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.045
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.045
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.045
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.044
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.044
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.044
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.043
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.043
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.043
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.043
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.043
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.042
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.042
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.041
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.041
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.041
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.041
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.041
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.040
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.040
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.040
|
|
|
|
stress induced premature senescence
|
GO:0090400 |
5 |
0.040
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
6 |
0.040
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.039
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.039
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.039
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.039
|
|
|
|
secretion by tissue
|
GO:0032941 |
9 |
0.038
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.038
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.037
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.037
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.037
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.036
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.036
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.036
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.036
|
Fly |
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.036
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.035
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.034
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.034
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.034
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.034
|
|
|
|
cellular response to drug
|
GO:0035690 |
27 |
0.034
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.034
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.034
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.034
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.034
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.034
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.034
|
|
|
|
growth
|
GO:0040007 |
202 |
0.034
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.033
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.033
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.033
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.033
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.033
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.032
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.032
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.031
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.031
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.031
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.031
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.031
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.031
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.031
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.030
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.030
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.030
|
|
|
|
regulation of fibroblast apoptotic process
|
GO:2000269 |
8 |
0.030
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.030
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.030
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.029
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.029
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.029
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.029
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.029
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.029
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.029
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.029
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.029
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.029
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.029
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.028
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
6 |
0.028
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.028
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.028
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.028
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.028
|
|
|
|
rrna metabolic process
|
GO:0016072 |
40 |
0.028
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.027
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.027
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.027
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.027
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.027
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.027
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.027
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.027
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.026
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.026
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.026
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.026
|
|
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.026
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.026
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.026
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.026
|
|
|
|
replicative senescence
|
GO:0090399 |
8 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.026
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.026
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.025
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.025
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.025
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.025
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
7 |
0.025
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.025
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.025
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.025
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.025
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.025
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.025
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.025
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.025
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.024
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.024
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.024
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.024
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.024
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.024
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.024
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.023
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.023
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.023
|
|
|
|
androgen biosynthetic process
|
GO:0006702 |
3 |
0.023
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.023
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.023
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.023
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
6 |
0.023
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.023
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.023
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.023
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.022
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.022
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.022
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.022
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.022
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.022
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.022
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.022
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.022
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.022
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.021
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.021
|
|
|
|
system process
|
GO:0003008 |
349 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.021
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.021
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.021
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.021
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.021
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.021
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.021
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.021
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.021
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.020
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.020
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.020
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.020
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.020
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.020
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.020
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.019
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.019
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.019
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.019
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.019
|
|
|
|
cellular response to estrogen stimulus
|
GO:0071391 |
16 |
0.019
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.019
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.019
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.019
|
|
|
|
mrna transcription
|
GO:0009299 |
8 |
0.019
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.019
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.019
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.019
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.018
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.018
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.018
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.018
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.018
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
2 |
0.018
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.018
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.018
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.018
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.018
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.018
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.018
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.018
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.017
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.017
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.017
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.017
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.017
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.017
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.017
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.017
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.017
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.017
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.017
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.017
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.017
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.017
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.017
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.017
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.017
|
|
|
|
translation
|
GO:0006412 |
132 |
0.017
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.017
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.017
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.017
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.017
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.017
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.016
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.016
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.016
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.016
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.016
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.016
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
12 |
0.016
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.016
|
|
