IMP
Process View
negative regulation of muscle organ development
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of muscle organ development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 1.000 | ||
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.995 | ||
| FSTL1 | follistatin-like 1 | 0.896 | ||
| SMAD1 | SMAD family member 1 | 0.845 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.749 | ||
| FGF10 | fibroblast growth factor 10 | 0.632 | Human | |
| HDAC3 | histone deacetylase 3 | 0.548 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.545 | Human | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.504 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.465 | ||
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.460 | ||
| ENG | endoglin | 0.389 | ||
| SMAD7 | SMAD family member 7 | 0.299 | Fly | |
| TGFB3 | transforming growth factor, beta 3 | 0.237 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.161 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.149 | Rat | |
| STK3 | serine/threonine kinase 3 | 0.116 | ||
| AXIN1 | axin 1 | 0.116 | ||
| MYOD1 | myogenic differentiation 1 | 0.113 | ||
| TTR | transthyretin | 0.099 | ||
| YAP1 | Yes-associated protein 1 | 0.089 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.086 | Mouse | |
| MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.079 | ||
| HIST1H3B | histone cluster 1, H3b | 0.068 | ||
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.065 | ||
| SMAD6 | SMAD family member 6 | 0.058 | Fly | |
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.056 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.054 | ||
| FGF7 | fibroblast growth factor 7 | 0.047 | Human | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.045 | ||
| GATA4 | GATA binding protein 4 | 0.044 | ||
| SATB2 | SATB homeobox 2 | 0.036 | ||
| NEURL4 | neuralized homolog 4 (Drosophila) | 0.032 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.031 | ||
| HPCAL4 | hippocalcin like 4 | 0.029 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.029 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.028 | ||
| PRDM8 | PR domain containing 8 | 0.028 | ||
| YY1 | YY1 transcription factor | 0.028 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.026 | ||
| FGF3 | fibroblast growth factor 3 | 0.025 | ||
| PHF10 | PHD finger protein 10 | 0.024 | ||
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.024 | ||
| FGF2 | fibroblast growth factor 2 (basic) | 0.023 | ||
| WWOX | WW domain containing oxidoreductase | 0.022 | ||
| HIST1H1E | histone cluster 1, H1e | 0.021 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.021 | ||
| TBX5 | T-box 5 | 0.020 | ||
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.020 | ||
| MKL2 | MKL/myocardin-like 2 | 0.018 | Human | |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.018 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.017 | ||
| TGFB2 | transforming growth factor, beta 2 | 0.017 | Human | |
| HDAC6 | histone deacetylase 6 | 0.017 | ||
| HDAC1 | histone deacetylase 1 | 0.016 | ||
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.016 | ||
| NRP1 | neuropilin 1 | 0.015 | ||
| SOX7 | SRY (sex determining region Y)-box 7 | 0.015 | ||
| DTX1 | deltex homolog 1 (Drosophila) | 0.015 | ||
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.015 | ||
| STAMBP | STAM binding protein | 0.014 | ||
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.014 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.014 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.014 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.014 | ||
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.014 | Human | |
| LBX1 | ladybird homeobox 1 | 0.013 | ||
| FGFR3 | fibroblast growth factor receptor 3 | 0.013 | ||
| KDM1A | lysine (K)-specific demethylase 1A | 0.013 | ||
| FOXA2 | forkhead box A2 | 0.012 | ||
| FOXF2 | forkhead box F2 | 0.012 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.012 | ||
| FGF4 | fibroblast growth factor 4 | 0.012 | Human | |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.012 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.012 | ||
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.011 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.011 | ||
| ACVR2B | activin A receptor, type IIB | 0.011 | ||
| S1PR5 | sphingosine-1-phosphate receptor 5 | 0.011 | ||
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.011 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.011 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.011 | ||
| BDNF | brain-derived neurotrophic factor | 0.010 | ||
| PLCE1 | phospholipase C, epsilon 1 | 0.010 | ||
| KCNQ1 | potassium voltage-gated channel, KQT-like subfamily, member 1 | 0.010 | ||
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.010 | ||
| COL2A1 | collagen, type II, alpha 1 | 0.010 | ||
| NPAS1 | neuronal PAS domain protein 1 | 0.010 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.010 |