Homo sapiens

8 known processes

SH2D1A

SH2 domain containing 1A

(Aliases: EBVS,IMD5,FLJ92177,SAP/SH2D1A,DSHP,MTCP1,XLPD,FLJ18687,LYP,SAP,XLP)

SH2D1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.982
Mouse
t cell activation GO:0042110 99 0.971
regulation of cytokine production GO:0001817 232 0.941
cytokine production GO:0001816 247 0.934
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.933
leukocyte activation GO:0045321 164 0.925
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.915
peptidyl tyrosine modification GO:0018212 170 0.887
peptidyl tyrosine phosphorylation GO:0018108 170 0.871
regulation of cell adhesion GO:0030155 166 0.825
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.808
cell activation GO:0001775 213 0.801
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.800
Mouse
lymphocyte activation GO:0046649 133 0.765
regulation of cellular amine metabolic process GO:0033238 11 0.749
antigen receptor mediated signaling pathway GO:0050851 38 0.722
regulation of astrocyte chemotaxis GO:2000458 1 0.708
hemopoiesis GO:0030097 180 0.706
regulation of lymphocyte activation GO:0051249 103 0.699
cell killing GO:0001906 34 0.682
Mouse
regulation of cell activation GO:0050865 125 0.675
positive regulation of apoptotic process GO:0043065 246 0.674
ras protein signal transduction GO:0007265 73 0.673
innate immune response GO:0045087 178 0.672
Mouse
lymphocyte mediated immunity GO:0002449 48 0.667
Mouse
positive regulation of t cell activation GO:0050870 54 0.635
regulation of cell killing GO:0031341 22 0.629
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.622
immune response regulating signaling pathway GO:0002764 97 0.620
defense response GO:0006952 315 0.617
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.598
regulation of leukocyte activation GO:0002694 115 0.574
regulation of immune effector process GO:0002697 91 0.551
Mouse
positive regulation of cell death GO:0010942 263 0.530
mononuclear cell proliferation GO:0032943 71 0.514
cellular amino acid metabolic process GO:0006520 116 0.499
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.485
positive regulation of lymphocyte activation GO:0051251 73 0.480
positive regulation of immune system process GO:0002684 283 0.475
Mouse
amine metabolic process GO:0009308 44 0.474
reactive nitrogen species metabolic process GO:2001057 3 0.449
immune system development GO:0002520 195 0.420
hematopoietic or lymphoid organ development GO:0048534 186 0.415
negative regulation of phosphate metabolic process GO:0045936 267 0.408
regulation of cellular ketone metabolic process GO:0010565 50 0.406
regulation of immune response GO:0050776 201 0.381
Mouse
regulation of t cell activation GO:0050863 77 0.371
negative regulation of protein metabolic process GO:0051248 391 0.369
natural killer cell mediated cytotoxicity GO:0042267 23 0.359
Mouse
positive regulation of cell killing GO:0031343 19 0.340
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.336
myeloid leukocyte activation GO:0002274 34 0.318
regulation of mononuclear cell proliferation GO:0032944 65 0.308
positive thymic t cell selection GO:0045059 1 0.301
regulation of lamellipodium morphogenesis GO:2000392 4 0.300
regulation of cellular component movement GO:0051270 334 0.299
positive regulation of immune response GO:0050778 159 0.293
Mouse
t cell receptor signaling pathway GO:0050852 21 0.282
negative regulation of phosphorylation GO:0042326 174 0.281
positive regulation of cell adhesion GO:0045785 84 0.279
protein localization to membrane GO:0072657 160 0.271
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.269
Mouse
regulation of natural killer cell activation GO:0032814 9 0.261
response to fibroblast growth factor GO:0071774 39 0.242
negative regulation of catalytic activity GO:0043086 335 0.241
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.236
immune response GO:0006955 307 0.230
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.217
single organism cell adhesion GO:0098602 179 0.214
regulation of cell motility GO:2000145 299 0.214
response to growth factor GO:0070848 205 0.210
positive regulation of protein transport GO:0051222 135 0.207
regulation of osteoclast differentiation GO:0045670 18 0.202
positive regulation of rac gtpase activity GO:0032855 31 0.190
positive regulation of programmed cell death GO:0043068 249 0.187
secretion GO:0046903 254 0.186
purine nucleoside catabolic process GO:0006152 398 0.183
positive regulation of phosphorylation GO:0042327 394 0.183
regulation of lymphocyte proliferation GO:0050670 64 0.182
negative regulation of protein phosphorylation GO:0001933 140 0.179
negative regulation of programmed cell death GO:0043069 321 0.179
regulation of protein kinase activity GO:0045859 289 0.178
regulation of cell migration GO:0030334 289 0.173
cellular response to endogenous stimulus GO:0071495 336 0.170
vesicle organization GO:0016050 62 0.168
regulation of interferon gamma production GO:0032649 36 0.161
positive regulation of fibroblast migration GO:0010763 3 0.158
regulation of protein serine threonine kinase activity GO:0071900 179 0.157
regulation of mapk cascade GO:0043408 262 0.157
cellular ketone metabolic process GO:0042180 80 0.157
positive regulation of cytokine production GO:0001819 167 0.153
single organism membrane fusion GO:0044801 37 0.150
cell cell junction organization GO:0045216 69 0.149
regulation of innate immune response GO:0045088 97 0.149
Mouse
cell junction assembly GO:0034329 67 0.147
regulation of oxidoreductase activity GO:0051341 43 0.143
cellular response to growth factor stimulus GO:0071363 197 0.141
negative regulation of cellular protein metabolic process GO:0032269 353 0.141
cell junction organization GO:0034330 79 0.139
neuron projection development GO:0031175 106 0.139
leukocyte mediated immunity GO:0002443 59 0.138
Mouse
cell type specific apoptotic process GO:0097285 125 0.138
single organism membrane organization GO:0044802 268 0.135
activation of immune response GO:0002253 114 0.134
organ morphogenesis GO:0009887 147 0.134
positive regulation of cell differentiation GO:0045597 211 0.132
phospholipid metabolic process GO:0006644 99 0.132
negative regulation of phosphorus metabolic process GO:0010563 267 0.131
small gtpase mediated signal transduction GO:0007264 78 0.130
reactive oxygen species biosynthetic process GO:1903409 4 0.129
regulation of transferase activity GO:0051338 355 0.127
positive regulation of lymphocyte proliferation GO:0050671 46 0.126
regulation of intracellular transport GO:0032386 195 0.125
natural killer cell mediated immunity GO:0002228 23 0.124
Mouse
positive regulation of mapk cascade GO:0043410 190 0.123
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.122
positive regulation of leukocyte activation GO:0002696 80 0.121
positive regulation of ion transport GO:0043270 87 0.121
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.120
protein localization to plasma membrane GO:0072659 93 0.120
extrinsic apoptotic signaling pathway GO:0097191 119 0.120
positive regulation of protein phosphorylation GO:0001934 313 0.119
regulation of peptidase activity GO:0052547 180 0.119
positive regulation of cell migration GO:0030335 172 0.119
negative regulation of hydrolase activity GO:0051346 182 0.114
negative regulation of immune effector process GO:0002698 38 0.114
regulation of lymphocyte mediated immunity GO:0002706 33 0.112
Mouse
cellular component morphogenesis GO:0032989 314 0.110
regulation of epithelial cell migration GO:0010632 93 0.106
positive regulation of locomotion GO:0040017 186 0.106
cytokine metabolic process GO:0042107 38 0.104
cell projection organization GO:0030030 252 0.102
negative regulation of multicellular organismal process GO:0051241 317 0.099
regulation of establishment of protein localization GO:0070201 242 0.098
response to hypoxia GO:0001666 96 0.098
negative regulation of immune system process GO:0002683 136 0.097
positive regulation of t cell proliferation GO:0042102 33 0.097
protein autophosphorylation GO:0046777 123 0.097
immune effector process GO:0002252 159 0.097
Mouse
membrane organization GO:0061024 292 0.096
biological adhesion GO:0022610 331 0.096
divalent inorganic cation homeostasis GO:0072507 136 0.095
negative regulation of protein processing GO:0010955 142 0.093
regulation of protein transport GO:0051223 213 0.089
neuron differentiation GO:0030182 138 0.089
cytokine biosynthetic process GO:0042089 37 0.088
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.087
positive regulation of cell motility GO:2000147 177 0.084
wound healing GO:0042060 115 0.084
negative regulation of cell death GO:0060548 345 0.083
glial cell migration GO:0008347 4 0.079
positive regulation of cell activation GO:0050867 81 0.079
negative regulation of endopeptidase activity GO:0010951 84 0.078
apoptotic signaling pathway GO:0097190 268 0.078
fibroblast migration GO:0010761 7 0.078
positive regulation of cell proliferation GO:0008284 301 0.077
lymphocyte proliferation GO:0046651 70 0.075
positive regulation of cellular amine metabolic process GO:0033240 7 0.075
negative regulation of apoptotic process GO:0043066 316 0.075
regulation of protein secretion GO:0050708 86 0.075
positive regulation of leukocyte proliferation GO:0070665 48 0.073
actin filament bundle organization GO:0061572 54 0.073
positive regulation of cell cycle GO:0045787 140 0.072
regulation of dna metabolic process GO:0051052 153 0.071
adherens junction organization GO:0034332 36 0.070
antigen processing and presentation endogenous lipid antigen via mhc class ib GO:0048006 1 0.070
dephosphorylation GO:0016311 209 0.070
organelle fusion GO:0048284 36 0.070
regulation of leukocyte differentiation GO:1902105 61 0.069
t cell proliferation GO:0042098 45 0.069
regulation of cell cycle GO:0051726 393 0.069
positive regulation of map kinase activity GO:0043406 80 0.067
positive regulation of cell substrate adhesion GO:0010811 37 0.067
negative regulation of proteolysis GO:0045861 132 0.067
t cell differentiation GO:0030217 29 0.065
positive regulation of cellular component movement GO:0051272 181 0.065
positive regulation of secretion GO:0051047 116 0.065
regulation of ras protein signal transduction GO:0046578 155 0.064
regulation of t cell proliferation GO:0042129 42 0.064
cytoplasmic transport GO:0016482 379 0.064
regeneration GO:0031099 4 0.063
interleukin 1 beta biosynthetic process GO:0050720 2 0.062
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.062
positive regulation of cellular catabolic process GO:0031331 284 0.062
protein maturation GO:0051604 233 0.060
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.060
cellular macromolecule catabolic process GO:0044265 380 0.060
determination of adult lifespan GO:0008340 2 0.059
multicellular organismal aging GO:0010259 3 0.059
positive regulation of cytoplasmic transport GO:1903651 82 0.059
tissue regeneration GO:0042246 3 0.057
chemical homeostasis GO:0048878 306 0.057
leukocyte proliferation GO:0070661 74 0.056
stress activated mapk cascade GO:0051403 93 0.056
regulation of erk1 and erk2 cascade GO:0070372 99 0.056
cytokine mediated signaling pathway GO:0019221 109 0.054
positive regulation of apoptotic signaling pathway GO:2001235 70 0.054
protein catabolic process GO:0030163 325 0.053
negative regulation of protein maturation GO:1903318 142 0.053
immune response activating signal transduction GO:0002757 90 0.053
negative regulation of kinase activity GO:0033673 106 0.052
positive regulation of osteoclast differentiation GO:0045672 9 0.052
regulation of locomotion GO:0040012 329 0.052
mapk cascade GO:0000165 288 0.052
cellular lipid metabolic process GO:0044255 303 0.051
focal adhesion assembly GO:0048041 30 0.051
positive regulation of hydrolase activity GO:0051345 331 0.050
lipid modification GO:0030258 84 0.050
positive regulation of gtpase activity GO:0043547 166 0.050
organelle assembly GO:0070925 176 0.049
response to decreased oxygen levels GO:0036293 96 0.048
positive regulation of t cell receptor signaling pathway GO:0050862 2 0.048
regulation of lipid metabolic process GO:0019216 96 0.048
positive regulation of developmental process GO:0051094 314 0.048
regulation of lipase activity GO:0060191 37 0.047
astrocyte chemotaxis GO:0035700 1 0.047
establishment of protein localization to organelle GO:0072594 172 0.047
protein processing GO:0016485 226 0.046
positive regulation of interleukin 8 secretion GO:2000484 9 0.046
single organism cellular localization GO:1902580 332 0.046
protein targeting GO:0006605 187 0.046
lymphocyte apoptotic process GO:0070227 20 0.046
regulation of cytoplasmic transport GO:1903649 149 0.045
i kappab kinase nf kappab signaling GO:0007249 166 0.045
interleukin 1 biosynthetic process GO:0042222 2 0.045
taxis GO:0042330 157 0.045
regulation of endothelial cell proliferation GO:0001936 56 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.043
regulation of epithelial cell proliferation GO:0050678 113 0.043
positive regulation of transport GO:0051050 336 0.043
positive regulation of neuron projection development GO:0010976 34 0.043
regulation of tumor necrosis factor production GO:0032680 43 0.043
peptidyl serine phosphorylation GO:0018105 101 0.043
neurogenesis GO:0022008 169 0.042
positive regulation of transferase activity GO:0051347 227 0.042
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.042
cell morphogenesis involved in differentiation GO:0000904 144 0.042
regulation of adaptive immune response GO:0002819 33 0.042
generation of neurons GO:0048699 152 0.041
negative regulation of catabolic process GO:0009895 104 0.041
regulation of alpha beta t cell activation GO:0046634 13 0.041
epithelial cell migration GO:0010631 119 0.041
response to other organism GO:0051707 261 0.041
regulation of kinase activity GO:0043549 314 0.041
endothelial cell proliferation GO:0001935 65 0.041
protein secretion GO:0009306 98 0.041
cell morphogenesis GO:0000902 296 0.041
single organismal cell cell adhesion GO:0016337 148 0.041
protein ubiquitination GO:0016567 314 0.041
regulation of binding GO:0051098 111 0.040
cellular homeostasis GO:0019725 196 0.040
positive regulation of leukocyte differentiation GO:1902107 37 0.040
neuromuscular junction development GO:0007528 3 0.039
rho protein signal transduction GO:0007266 26 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
regulation of cell projection organization GO:0031344 107 0.039
protein localization to nucleus GO:0034504 136 0.038
activation of mapk activity GO:0000187 45 0.038
regulation of proteolysis GO:0030162 293 0.038
regulation of rho protein signal transduction GO:0035023 79 0.038
segmentation GO:0035282 4 0.038
cell substrate junction assembly GO:0007044 35 0.038
regulation of cell differentiation GO:0045595 393 0.037
vesicle fusion GO:0006906 17 0.037
positive regulation of neuron differentiation GO:0045666 40 0.037
cell substrate adhesion GO:0031589 132 0.037
positive regulation of kinase activity GO:0033674 204 0.037
regulation of homeostatic process GO:0032844 121 0.037
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.036
negative regulation of intracellular signal transduction GO:1902532 183 0.035
activation of protein kinase activity GO:0032147 90 0.035
lamellipodium organization GO:0097581 30 0.035
positive regulation of catabolic process GO:0009896 310 0.035
alcohol metabolic process GO:0006066 114 0.035
response to cytokine GO:0034097 232 0.035
regulation of leukocyte proliferation GO:0070663 67 0.034
cell adhesion GO:0007155 325 0.034
negative regulation of protein modification process GO:0031400 200 0.034
regulation of secretion GO:0051046 194 0.034
stress fiber assembly GO:0043149 40 0.033
negative regulation of lymphocyte mediated immunity GO:0002707 12 0.033
interleukin 17 production GO:0032620 12 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.032
regulation of cytokine biosynthetic process GO:0042035 35 0.032
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.032
convergent extension involved in gastrulation GO:0060027 1 0.032
nuclear import GO:0051170 106 0.032
protein localization to organelle GO:0033365 280 0.032
regulation of protein complex assembly GO:0043254 147 0.032
t cell homeostasis GO:0043029 3 0.031
mitotic cell cycle process GO:1903047 286 0.031
negative regulation of monocyte differentiation GO:0045656 3 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
regulation of bone resorption GO:0045124 4 0.031
regulation of protein targeting GO:1903533 91 0.031
leukocyte apoptotic process GO:0071887 31 0.031
actin filament based process GO:0030029 224 0.031
negative regulation of endodeoxyribonuclease activity GO:0032078 1 0.030
mitotic cell cycle GO:0000278 326 0.030
positive regulation of dna metabolic process GO:0051054 73 0.030
regulation of rho gtpase activity GO:0032319 66 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.030
sequestering of calcium ion GO:0051208 17 0.030
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.030
negative regulation of t cell apoptotic process GO:0070233 4 0.030
organophosphate catabolic process GO:0046434 430 0.030
positive regulation of behavior GO:0048520 60 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
regulation of hormone levels GO:0010817 125 0.029
alpha beta t cell activation GO:0046631 15 0.029
nucleocytoplasmic transport GO:0006913 176 0.029
regulation of glycogen metabolic process GO:0070873 15 0.029
endomembrane system organization GO:0010256 196 0.028
chemotaxis GO:0006935 157 0.028
positive regulation of gliogenesis GO:0014015 4 0.028
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.028
regulation of endothelial cell apoptotic process GO:2000351 24 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.028
intracellular protein transport GO:0006886 270 0.028
regulation of protein maturation GO:1903317 150 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.028
secretion by cell GO:0032940 226 0.028
multicellular organismal homeostasis GO:0048871 67 0.028
regulation of cell substrate adhesion GO:0010810 68 0.027
single organism nuclear import GO:1902593 104 0.027
regulation of dna repair GO:0006282 47 0.027
positive regulation of cell development GO:0010720 92 0.027
lipid transport GO:0006869 90 0.027
positive regulation of lipid metabolic process GO:0045834 50 0.027
b cell proliferation GO:0042100 22 0.027
regulation of cell growth GO:0001558 135 0.027
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.027
cell growth GO:0016049 160 0.027
positive regulation of proteolysis GO:0045862 142 0.027
regulation of cytoskeleton organization GO:0051493 177 0.026
phosphatidylinositol mediated signaling GO:0048015 55 0.026
cell cell signaling GO:0007267 155 0.026
regulation of calcium mediated signaling GO:0050848 17 0.026
negative regulation of protein homooligomerization GO:0032463 4 0.026
transmembrane transport GO:0055085 399 0.026
protein homooligomerization GO:0051260 100 0.026
positive regulation of cell growth GO:0030307 48 0.026
lipid localization GO:0010876 106 0.026
negative regulation of peptidase activity GO:0010466 91 0.026
ameboidal type cell migration GO:0001667 135 0.026
protein import into nucleus GO:0006606 104 0.025
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.025
blood vessel endothelial cell migration GO:0043534 42 0.025
regulation of glial cell proliferation GO:0060251 4 0.025
cellular response to peptide hormone stimulus GO:0071375 56 0.025
regulation of apoptotic signaling pathway GO:2001233 175 0.025
regulation of reactive oxygen species metabolic process GO:2000377 41 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
regulation of small gtpase mediated signal transduction GO:0051056 156 0.025
negative regulation of transport GO:0051051 176 0.025
negative regulation of map kinase activity GO:0043407 27 0.024
protein import GO:0017038 130 0.024
positive regulation of cell division GO:0051781 59 0.024
locomotory behavior GO:0007626 1 0.024
t cell selection GO:0045058 4 0.024
response to mercury ion GO:0046689 4 0.024
neuron death GO:0070997 65 0.024
detection of mechanical stimulus GO:0050982 4 0.024
actin filament bundle assembly GO:0051017 54 0.024
cell development GO:0048468 328 0.024
regulation of map kinase activity GO:0043405 108 0.024
regulation of protein localization to plasma membrane GO:1903076 40 0.024
regulation of protein import into nucleus GO:0042306 78 0.024
regulation of cell cycle process GO:0010564 266 0.024
regulation of cytokine secretion GO:0050707 57 0.024
angiogenesis GO:0001525 147 0.024
positive regulation of secretion by cell GO:1903532 108 0.024
regulation of neuron projection development GO:0010975 57 0.024
negative regulation of cell proliferation GO:0008285 228 0.023
amide transport GO:0042886 76 0.023
nuclear transport GO:0051169 179 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.023
epithelium development GO:0060429 227 0.023
carbohydrate metabolic process GO:0005975 207 0.023
regulation of protein localization GO:0032880 296 0.023
calcium mediated signaling GO:0019722 44 0.023
cellular chemical homeostasis GO:0055082 180 0.023
glycosyl compound catabolic process GO:1901658 413 0.022
lamellipodium assembly GO:0030032 26 0.022
fatty acid catabolic process GO:0009062 29 0.022
protein dephosphorylation GO:0006470 81 0.022
regulation of myeloid cell differentiation GO:0045637 81 0.022
dna catabolic process GO:0006308 49 0.022
maintenance of cell polarity GO:0030011 2 0.022
regulation of mismatch repair GO:0032423 2 0.022
regulation of endopeptidase activity GO:0052548 170 0.022
leukocyte differentiation GO:0002521 98 0.022
regulation of neuron apoptotic process GO:0043523 35 0.022
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.022
response to wounding GO:0009611 168 0.022
regulation of b cell receptor signaling pathway GO:0050855 4 0.022
negative regulation of protein catabolic process GO:0042177 59 0.022
regulation of nitric oxide biosynthetic process GO:0045428 17 0.022
response to abiotic stimulus GO:0009628 336 0.022
response to uv GO:0009411 73 0.021
positive regulation of calcium mediated signaling GO:0050850 10 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
spermatid development GO:0007286 4 0.021
positive regulation of mononuclear cell proliferation GO:0032946 47 0.021
regulation of protein processing GO:0070613 150 0.021
carboxylic acid catabolic process GO:0046395 71 0.021
regulation of cellular response to stress GO:0080135 244 0.021
hindbrain development GO:0030902 3 0.021
ribonucleoprotein complex assembly GO:0022618 78 0.021
anatomical structure homeostasis GO:0060249 100 0.021
motor neuron axon guidance GO:0008045 2 0.021
positive regulation of protein secretion GO:0050714 60 0.021
dna repair GO:0006281 198 0.020
cellular amide metabolic process GO:0043603 69 0.020
lipid biosynthetic process GO:0008610 177 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
endothelial cell migration GO:0043542 86 0.020
positive regulation of leukocyte migration GO:0002687 46 0.020
microtubule based process GO:0007017 210 0.020
ribonucleoprotein complex subunit organization GO:0071826 81 0.020
regulation of cell division GO:0051302 116 0.020
regulation of anatomical structure size GO:0090066 101 0.020
cellular protein catabolic process GO:0044257 261 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
positive regulation of phospholipid transport GO:2001140 4 0.020
interferon gamma production GO:0032609 39 0.020
response to oxygen levels GO:0070482 100 0.020
regulation of neurogenesis GO:0050767 82 0.020
carbohydrate biosynthetic process GO:0016051 42 0.020
positive regulation of cytoskeleton organization GO:0051495 83 0.020
peptide transport GO:0015833 74 0.019
ribonucleoprotein complex biogenesis GO:0022613 116 0.019
adherens junction assembly GO:0034333 34 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
negative regulation of mapk cascade GO:0043409 56 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
lipid metabolic process GO:0006629 381 0.019
epithelium migration GO:0090132 119 0.019
positive regulation of oxidoreductase activity GO:0051353 26 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
regulation of cell development GO:0060284 161 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
anion transport GO:0006820 161 0.019
vesicle mediated transport GO:0016192 371 0.019
negative regulation of cytokine production GO:0001818 82 0.019
regulation of cellular response to insulin stimulus GO:1900076 17 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
phagocytosis recognition GO:0006910 3 0.019
negative regulation of fatty acid oxidation GO:0046322 1 0.019
autophagy GO:0006914 88 0.019
regulation of cysteine type endopeptidase activity GO:2000116 127 0.019
cell junction maintenance GO:0034331 4 0.019
t cell differentiation in thymus GO:0033077 4 0.019
endochondral ossification GO:0001958 1 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
regulation of interleukin 8 production GO:0032677 49 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
response to virus GO:0009615 126 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
positive regulation of organelle organization GO:0010638 195 0.018
platelet activation GO:0030168 44 0.018
regulation of chemotaxis GO:0050920 74 0.018
negative regulation of cell killing GO:0031342 5 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
regulation of cell cell adhesion GO:0022407 57 0.018
response to peptide hormone GO:0043434 61 0.018
interleukin 8 secretion GO:0072606 14 0.018
myeloid cell differentiation GO:0030099 117 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
regulation of protein catabolic process GO:0042176 155 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
negative regulation of neuron apoptotic process GO:0043524 23 0.017
embryonic viscerocranium morphogenesis GO:0048703 1 0.017
embryo development GO:0009790 123 0.017
regulation of secretion by cell GO:1903530 177 0.017
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.017
cellular response to lipid GO:0071396 127 0.017
cell substrate adherens junction assembly GO:0007045 30 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
regulation of lipid kinase activity GO:0043550 19 0.017
membrane lipid biosynthetic process GO:0046467 27 0.017
regulation of ion transmembrane transport GO:0034765 132 0.017
post embryonic development GO:0009791 2 0.017
cell part morphogenesis GO:0032990 137 0.017
positive regulation of adaptive immune response GO:0002821 21 0.017
regulation of carbohydrate metabolic process GO:0006109 54 0.017
negative regulation of intracellular transport GO:0032387 60 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
cell projection assembly GO:0030031 126 0.017

SH2D1A disease predictions

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 88 0.324
musculoskeletal system disease DOID:17 223 0.324
connective tissue disease DOID:65 109 0.324
disease of mental health DOID:150 70 0.045
developmental disorder of mental health DOID:0060037 29 0.045
specific developmental disorder DOID:0060038 19 0.018