IMP
Process View
protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| UBC | ubiquitin C | 1.000 | Worm | |
| RNF11 | ring finger protein 11 | 1.000 | ||
| TP53 | tumor protein p53 | 1.000 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 1.000 | ||
| VCP | valosin containing protein | 1.000 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 1.000 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 1.000 | Yeast Worm | |
| CUL1 | cullin 1 | 0.999 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.999 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.998 | Human Yeast | |
| SQSTM1 | sequestosome 1 | 0.998 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.998 | ||
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.998 | Yeast | |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.998 | Yeast | |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.997 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.996 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.995 | Human | |
| SNX9 | sorting nexin 9 | 0.995 | ||
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.994 | Yeast | |
| CUL2 | cullin 2 | 0.994 | Mouse Worm | |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.993 | Yeast | |
| BTRC | beta-transducin repeat containing | 0.993 | ||
| CREBBP | CREB binding protein | 0.993 | ||
| SMAD2 | SMAD family member 2 | 0.993 | Human | |
| SMAD3 | SMAD family member 3 | 0.992 | ||
| RB1 | retinoblastoma 1 | 0.991 | ||
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.988 | Yeast | |
| UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.987 | Mouse | |
| HSPA8 | heat shock 70kDa protein 8 | 0.987 | ||
| CUL3 | cullin 3 | 0.986 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.985 | ||
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.985 | Yeast | |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.983 | Yeast | |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.983 | Yeast | |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.983 | Yeast | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.982 | Worm | |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.980 | Yeast | |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.980 | Yeast | |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.979 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.978 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.977 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.976 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.976 | ||
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.974 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.973 | ||
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.971 | Yeast | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.971 | ||
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.967 | ||
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.965 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.965 | ||
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.962 | Yeast Mouse | |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.962 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.961 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.959 | Rat | |
| UBQLN1 | ubiquilin 1 | 0.954 | Human | |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.953 | Worm | |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.949 | Yeast | |
| POMP | proteasome maturation protein | 0.947 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.946 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.944 | ||
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.941 | Mouse | |
| RNF111 | ring finger protein 111 | 0.936 | Mouse | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.933 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.928 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.928 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.926 | Fly | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.914 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.906 | Human | |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.902 | Worm | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.898 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.898 | Worm | |
| DERL1 | Der1-like domain family, member 1 | 0.896 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.894 | Human Mouse | |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.893 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.893 | ||
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.871 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.870 | ||
| HDAC1 | histone deacetylase 1 | 0.868 | ||
| GABARAP | GABA(A) receptor-associated protein | 0.866 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.863 | ||
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.862 | ||
| HSPA4 | heat shock 70kDa protein 4 | 0.861 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.859 | ||
| PSAP | prosaposin | 0.855 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.853 | ||
| TRIM39 | tripartite motif containing 39 | 0.848 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.846 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.845 | ||
| MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.843 | ||
| PXN | paxillin | 0.843 | Human | |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.841 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.837 | Human | |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.834 | Fly | |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.833 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.820 | Human | |
| PML | promyelocytic leukemia | 0.804 | ||
| UBXN7 | UBX domain protein 7 | 0.803 | Yeast | |
| BRCA1 | breast cancer 1, early onset | 0.803 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.799 | ||
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.794 | ||
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.779 | Yeast | |
| UBE3A | ubiquitin protein ligase E3A | 0.774 | Mouse Fly | |
| SMAD7 | SMAD family member 7 | 0.773 | ||
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.768 | ||
| RNF5 | ring finger protein 5 | 0.767 | ||
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.767 | Yeast Mouse | |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.761 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.760 | Yeast | |
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.753 | Mouse Fly | |
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.750 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.743 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.741 | Human | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.739 | Human Yeast | |
| BAG3 | BCL2-associated athanogene 3 | 0.736 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.734 | ||
| CCNA2 | cyclin A2 | 0.732 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.727 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.720 | ||
| FN1 | fibronectin 1 | 0.717 | ||
| SETDB1 | SET domain, bifurcated 1 | 0.706 | ||
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.703 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.702 | Human Mouse | |
| UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.693 | Human Yeast Fly | |
| ZNRF1 | zinc and ring finger 1 | 0.692 | Mouse | |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.690 | ||
| TRIM28 | tripartite motif containing 28 | 0.687 | Human | |
| SMAD4 | SMAD family member 4 | 0.684 | ||
| PPP5C | protein phosphatase 5, catalytic subunit | 0.682 | ||
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.678 | Worm | |
| VHL | von Hippel-Lindau tumor suppressor | 0.678 | Mouse | |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.676 | Yeast | |
| TADA3 | transcriptional adaptor 3 | 0.675 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.671 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.669 | ||
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.668 | ||
| ATXN3 | ataxin 3 | 0.667 | Mouse | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.666 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.665 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.663 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.660 | Human | |
| PLK1 | polo-like kinase 1 | 0.659 | ||
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.655 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.653 | Mouse Fly | |
| FBXO5 | F-box protein 5 | 0.652 | ||
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.650 | Yeast | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.648 | Mouse Worm | |
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.647 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.647 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.645 | ||
| CBX5 | chromobox homolog 5 | 0.645 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.644 | Human | |
| RNF126 | ring finger protein 126 | 0.643 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.643 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.642 | ||
| FHL2 | four and a half LIM domains 2 | 0.637 | ||
| MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.633 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.633 | Mouse | |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.628 | ||
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.628 | Mouse | |
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.627 | ||
| GRN | granulin | 0.627 | ||
| AMFR | autocrine motility factor receptor | 0.624 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.621 | ||
| ARRB1 | arrestin, beta 1 | 0.618 | ||
| CUL5 | cullin 5 | 0.615 | ||
| EP300 | E1A binding protein p300 | 0.613 | ||
| ILK | integrin-linked kinase | 0.610 | Worm | |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.609 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.608 | Yeast | |
| RNF7 | ring finger protein 7 | 0.601 | ||
| RNF2 | ring finger protein 2 | 0.599 | ||
| AXIN1 | axin 1 | 0.599 | ||
| AR | androgen receptor | 0.599 | ||
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.599 | Human | |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.598 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.596 | Human | |
| HSPA1B | heat shock 70kDa protein 1B | 0.596 | Yeast | |
| TRIM63 | tripartite motif containing 63 | 0.591 | Human Mouse | |
| SSR1 | signal sequence receptor, alpha | 0.589 | ||
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.582 | Yeast | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.581 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.576 | Human | |
| PSEN1 | presenilin 1 | 0.574 | Mouse | |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.572 | ||
| CUL4A | cullin 4A | 0.572 | Mouse | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.567 | Fly | |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.567 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.565 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.565 | Mouse | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.562 | ||
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.558 | ||
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.557 | Yeast | |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.556 | ||
| H2AFX | H2A histone family, member X | 0.555 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.550 | ||
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.549 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.549 | ||
| YY1 | YY1 transcription factor | 0.546 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.541 | ||
| FBXO7 | F-box protein 7 | 0.531 | ||
| TLK1 | tousled-like kinase 1 | 0.531 | Human | |
| ANAPC7 | anaphase promoting complex subunit 7 | 0.521 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.513 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.513 | ||
| HSPA1A | heat shock 70kDa protein 1A | 0.499 | Yeast | |
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.494 | ||
| FLNB | filamin B, beta | 0.494 | Human | |
| NBR1 | neighbor of BRCA1 gene 1 | 0.493 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.493 | Human | |
| SEPT2 | septin 2 | 0.489 | ||
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.479 | ||
| FLNA | filamin A, alpha | 0.473 | ||
| YAP1 | Yes-associated protein 1 | 0.468 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.465 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.460 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.460 | ||
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.453 | Mouse | |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.452 | Yeast | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.451 | ||
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.448 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.447 | ||
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.445 | ||
| RYBP | RING1 and YY1 binding protein | 0.443 | Fly | |
| KDM1A | lysine (K)-specific demethylase 1A | 0.442 | ||
| UBXN1 | UBX domain protein 1 | 0.439 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.439 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.439 | ||
| ANXA7 | annexin A7 | 0.434 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.434 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.433 | ||
| EGFR | epidermal growth factor receptor | 0.433 | ||
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.432 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.432 | Human | |
| MBD3 | methyl-CpG binding domain protein 3 | 0.432 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.430 | ||
| FBXW2 | F-box and WD repeat domain containing 2 | 0.429 | ||
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.426 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.426 | ||
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.418 | Mouse | |
| NCF2 | neutrophil cytosolic factor 2 | 0.414 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.413 | ||
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.413 | Human Yeast | |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.412 | Human | |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.412 | ||
| PLEC | plectin | 0.411 | ||
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.411 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.409 | Human | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.408 | ||
| MYH9 | myosin, heavy chain 9, non-muscle | 0.402 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.402 | ||
| FBXO33 | F-box protein 33 | 0.399 | ||
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.398 | ||
| SELS | selenoprotein S | 0.396 | ||
| UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.393 | Yeast Mouse | |
| PKM2 | pyruvate kinase, muscle | 0.392 | ||
| WDR26 | WD repeat domain 26 | 0.391 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.390 | Zebrafish | |
| MYOZ1 | myozenin 1 | 0.387 | ||
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.387 | ||
| RNF20 | ring finger protein 20 | 0.379 | ||
| PRKCA | protein kinase C, alpha | 0.379 | ||
| DNM1 | dynamin 1 | 0.379 | ||
| TRIM43 | tripartite motif containing 43 | 0.379 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.379 | Human | |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.376 | ||
| KEAP1 | kelch-like ECH-associated protein 1 | 0.375 | ||
| VCL | vinculin | 0.375 | Worm | |
| RNF168 | ring finger protein 168 | 0.369 | ||
| MKRN1 | makorin ring finger protein 1 | 0.367 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.365 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.364 | ||
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.361 | ||
| LMNA | lamin A/C | 0.360 | Worm | |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.357 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.354 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.353 | ||
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.352 | ||
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.352 | Yeast | |
| CTGF | connective tissue growth factor | 0.350 | ||
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.350 | Mouse | |
| NAP1L5 | nucleosome assembly protein 1-like 5 | 0.348 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.347 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.347 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.346 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.343 | ||
| ATM | ataxia telangiectasia mutated | 0.340 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.339 | ||
| ZNF496 | zinc finger protein 496 | 0.338 | ||
| DAXX | death-domain associated protein | 0.335 | ||
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.335 | Human | |
| MPDZ | multiple PDZ domain protein | 0.333 | ||
| TRIM21 | tripartite motif containing 21 | 0.333 | Human | |
| HTT | huntingtin | 0.332 | ||
| RANBP2 | RAN binding protein 2 | 0.330 | ||
| TGS1 | trimethylguanosine synthase 1 | 0.328 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.328 | ||
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.327 | ||
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.326 | ||
| IER3 | immediate early response 3 | 0.325 | Mouse | |
| ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.324 | Worm | |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.323 | ||
| BAD | BCL2-associated agonist of cell death | 0.322 | ||
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.321 | Mouse | |
| ATXN1 | ataxin 1 | 0.320 | ||
| PJA2 | praja ring finger 2 | 0.319 | ||
| FAF2 | Fas associated factor family member 2 | 0.318 | Human | |
| TGFB1 | transforming growth factor, beta 1 | 0.318 | ||
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.317 | Human | |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.317 | ||
| EXOC5 | exocyst complex component 5 | 0.317 | ||
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.315 | ||
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.312 | ||
| NBN | nibrin | 0.312 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.311 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.310 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.307 | ||
| ZYX | zyxin | 0.303 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.302 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.301 | Human | |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.298 | ||
| OPTN | optineurin | 0.297 | ||
| EPAS1 | endothelial PAS domain protein 1 | 0.296 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.296 | Rat | |
| JUN | jun proto-oncogene | 0.293 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.292 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.292 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.291 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.290 | ||
| CHFR | checkpoint with forkhead and ring finger domains | 0.290 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.289 | Human | |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.288 | Rat | |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.287 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.287 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.287 | ||
| ITGB4 | integrin, beta 4 | 0.284 | Worm | |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.280 | ||
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.279 | Human | |
| TEKT4 | tektin 4 | 0.278 | ||
| ANKRD28 | ankyrin repeat domain 28 | 0.276 | ||
| PRNP | prion protein | 0.276 | ||
| UBQLN2 | ubiquilin 2 | 0.272 | Human | |
| RNF31 | ring finger protein 31 | 0.271 | ||
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.271 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.270 | ||
| SMAD5 | SMAD family member 5 | 0.270 | Human | |
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.269 | Human Mouse | |
| SMAD1 | SMAD family member 1 | 0.269 | Human | |
| FNBP1 | formin binding protein 1 | 0.269 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.264 | Worm | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.263 | ||
| STK24 | serine/threonine kinase 24 | 0.262 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.262 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.261 | ||
| TRIM32 | tripartite motif containing 32 | 0.259 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.258 | Yeast | |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.258 | Mouse | |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.258 | Human Yeast Mouse Worm | |
| LRRK2 | leucine-rich repeat kinase 2 | 0.257 | Mouse | |
| MAGED1 | melanoma antigen family D, 1 | 0.257 | ||
| CCNB1 | cyclin B1 | 0.256 | ||
| SFN | stratifin | 0.256 | ||
| RHOB | ras homolog gene family, member B | 0.256 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.256 | ||
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.255 | Yeast | |
| IL1R1 | interleukin 1 receptor, type I | 0.255 | ||
| BABAM1 | BRISC and BRCA1 A complex member 1 | 0.252 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.250 | ||
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.249 | Human | |
| CENPJ | centromere protein J | 0.249 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.248 | Worm | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.248 | ||
| UBXN6 | UBX domain protein 6 | 0.246 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.245 | Human | |
| CALD1 | caldesmon 1 | 0.245 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.244 | ||
| MYO1C | myosin IC | 0.243 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.243 | ||
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.243 | Human | |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.242 | Yeast | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.242 | ||
| MAGEA3 | melanoma antigen family A, 3 | 0.242 | ||
| LNX1 | ligand of numb-protein X 1 | 0.242 | Mouse | |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.242 | Fly | |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.241 | ||
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.240 | ||
| KCTD10 | potassium channel tetramerisation domain containing 10 | 0.239 | Human | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.238 | Human | |
| MTA2 | metastasis associated 1 family, member 2 | 0.237 | Human | |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.236 | ||
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.235 | ||
| ENG | endoglin | 0.235 | ||
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.234 | Human | |
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.234 | Fly | |
| ARRDC3 | arrestin domain containing 3 | 0.233 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.233 | Fly | |
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.233 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.233 | ||
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.232 | Worm | |
| CCNE2 | cyclin E2 | 0.232 | Fly | |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.231 | ||
| NOXA1 | NADPH oxidase activator 1 | 0.231 | ||
| BAX | BCL2-associated X protein | 0.231 | ||
| VTA1 | Vps20-associated 1 homolog (S. cerevisiae) | 0.230 | ||
| MAGEA6 | melanoma antigen family A, 6 | 0.230 | Human | |
| TRIM9 | tripartite motif containing 9 | 0.230 | ||
| APP | amyloid beta (A4) precursor protein | 0.226 | ||
| BCAP31 | B-cell receptor-associated protein 31 | 0.226 | ||
| RNF130 | ring finger protein 130 | 0.225 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.225 | ||
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.225 | ||
| CD63 | CD63 molecule | 0.225 | ||
| CARM1 | coactivator-associated arginine methyltransferase 1 | 0.224 | ||
| SNX33 | sorting nexin 33 | 0.224 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.224 | Mouse | |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.223 | ||
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.222 | ||
| ACTB | actin, beta | 0.222 | ||
| CTAG1B | cancer/testis antigen 1B | 0.221 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.221 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.220 | ||
| ATF3 | activating transcription factor 3 | 0.219 | ||
| FOXM1 | forkhead box M1 | 0.218 | ||
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.216 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.214 | ||
| RNF8 | ring finger protein 8 | 0.214 | ||
| S100A4 | S100 calcium binding protein A4 | 0.213 | ||
| HDAC6 | histone deacetylase 6 | 0.213 | ||
| WDR48 | WD repeat domain 48 | 0.212 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.212 | ||
| TCP1 | t-complex 1 | 0.212 | ||
| MAGEA2 | melanoma antigen family A, 2 | 0.210 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.209 | ||
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.208 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.208 | ||
| FBXW5 | F-box and WD repeat domain containing 5 | 0.208 | ||
| LDLR | low density lipoprotein receptor | 0.207 | Mouse | |
| AURKB | aurora kinase B | 0.206 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.205 | ||
| BMP2 | bone morphogenetic protein 2 | 0.205 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.204 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.203 | Fly | |
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.201 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.201 | ||
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.201 | Yeast | |
| FERMT2 | fermitin family member 2 | 0.201 | Worm | |
| ATP13A2 | ATPase type 13A2 | 0.200 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.199 | ||
| ANXA1 | annexin A1 | 0.199 | ||
| RANBP9 | RAN binding protein 9 | 0.199 | ||
| USP15 | ubiquitin specific peptidase 15 | 0.199 | Human | |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.197 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.194 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.194 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.193 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.190 | ||
| HERC2 | hect domain and RLD 2 | 0.189 | ||
| CDCA4 | cell division cycle associated 4 | 0.189 | ||
| HIST2H3C | histone cluster 2, H3c | 0.188 | Yeast | |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.188 | ||
| FBXO3 | F-box protein 3 | 0.188 | ||
| RNF4 | ring finger protein 4 | 0.186 | ||
| APC | adenomatous polyposis coli | 0.185 | ||
| RNF14 | ring finger protein 14 | 0.185 | ||
| ADAM12 | ADAM metallopeptidase domain 12 | 0.184 | ||
| CCNB2 | cyclin B2 | 0.183 | ||
| BAG6 | BCL2-associated athanogene 6 | 0.183 | Mouse | |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.182 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.182 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.182 | Human | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.181 | ||
| MEOX2 | mesenchyme homeobox 2 | 0.180 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.179 | Human | |
| STAT5A | signal transducer and activator of transcription 5A | 0.179 | ||
| A2M | alpha-2-macroglobulin | 0.178 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.178 | ||
| PCBP2 | poly(rC) binding protein 2 | 0.178 | ||
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.178 | ||
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.178 | ||
| KLC1 | kinesin light chain 1 | 0.178 | ||
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.178 | ||
| ITGB5 | integrin, beta 5 | 0.178 | Worm | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.177 | ||
| TPBG | trophoblast glycoprotein | 0.176 | ||
| CD14 | CD14 molecule | 0.176 | ||
| THBS1 | thrombospondin 1 | 0.175 | ||
| KALRN | kalirin, RhoGEF kinase | 0.174 | Worm | |
| MIB1 | mindbomb homolog 1 (Drosophila) | 0.174 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.174 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.174 | Yeast | |
| ITK | IL2-inducible T-cell kinase | 0.174 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.174 | ||
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.173 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.173 | ||
| ATG13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.173 | ||
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.173 | Human | |
| TRIM5 | tripartite motif containing 5 | 0.172 | Human Mouse | |
| RNF185 | ring finger protein 185 | 0.172 | Human | |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.171 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.170 | ||
| HTRA2 | HtrA serine peptidase 2 | 0.170 | ||
| USP34 | ubiquitin specific peptidase 34 | 0.169 | ||
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.168 | ||
| DAPK1 | death-associated protein kinase 1 | 0.168 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.168 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.167 | ||
| TSG101 | tumor susceptibility gene 101 | 0.164 | ||
| UBA3 | ubiquitin-like modifier activating enzyme 3 | 0.164 | ||
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.163 | ||
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | 0.162 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.161 | ||
| IL1RAP | interleukin 1 receptor accessory protein | 0.160 | ||
| SON | SON DNA binding protein | 0.160 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.160 | ||
| FOXO3 | forkhead box O3 | 0.159 | Human | |
| BFAR | bifunctional apoptosis regulator | 0.159 | ||
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.158 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.158 | ||
| RNF144B | ring finger protein 144B | 0.157 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.157 | ||
| IL22RA2 | interleukin 22 receptor, alpha 2 | 0.156 | ||
| AGAP5 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 | 0.155 | Human | |
| SP1 | Sp1 transcription factor | 0.155 | ||
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.155 | ||
| CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.155 | ||
| BMP1 | bone morphogenetic protein 1 | 0.154 | ||
| NDUFAF3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3 | 0.154 | ||
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.154 | ||
| CCDC115 | coiled-coil domain containing 115 | 0.153 | ||
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.153 | ||
| VPRBP | Vpr (HIV-1) binding protein | 0.151 | ||
| NRP1 | neuropilin 1 | 0.151 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.151 | Human | |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.151 | ||
| RNF10 | ring finger protein 10 | 0.151 | ||
| SESN2 | sestrin 2 | 0.150 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.150 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.150 | ||
| FEN1 | flap structure-specific endonuclease 1 | 0.150 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.149 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.149 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.148 | ||
| SOCS5 | suppressor of cytokine signaling 5 | 0.146 | ||
| BAK1 | BCL2-antagonist/killer 1 | 0.146 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.146 | Mouse | |
| ZBTB8A | zinc finger and BTB domain containing 8A | 0.146 | ||
| CSNK1D | casein kinase 1, delta | 0.145 | Mouse Fly | |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.145 | ||
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.145 | ||
| PTEN | phosphatase and tensin homolog | 0.145 | ||
| SNX6 | sorting nexin 6 | 0.145 | ||
| PCBP1 | poly(rC) binding protein 1 | 0.144 | Human | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.144 | Worm | |
| ZNF746 | zinc finger protein 746 | 0.144 | ||
| TLR2 | toll-like receptor 2 | 0.144 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.143 | ||
| C11orf58 | chromosome 11 open reading frame 58 | 0.143 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.143 | Human | |
| NCAM1 | neural cell adhesion molecule 1 | 0.143 | ||
| NUDCD3 | NudC domain containing 3 | 0.142 | ||
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.142 | ||
| CKAP5 | cytoskeleton associated protein 5 | 0.142 | ||
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.141 | Yeast | |
| ATG4B | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 0.141 | ||
| EID2 | EP300 interacting inhibitor of differentiation 2 | 0.141 | ||
| RIOK3 | RIO kinase 3 (yeast) | 0.140 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.140 | ||
| CLOCK | clock homolog (mouse) | 0.140 | Mouse | |
| ACVR1 | activin A receptor, type I | 0.140 | Worm | |
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.140 | ||
| MAGEB18 | melanoma antigen family B, 18 | 0.139 | Human | |
| GSTO1 | glutathione S-transferase omega 1 | 0.139 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.138 | ||
| EPOR | erythropoietin receptor | 0.138 | ||
| PRKCD | protein kinase C, delta | 0.137 | Human | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.137 | ||
| MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.137 | ||
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.137 | ||
| DTX1 | deltex homolog 1 (Drosophila) | 0.137 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.136 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.136 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.136 | Worm | |
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.136 | Human | |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.136 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.135 | ||
| TRIM34 | tripartite motif containing 34 | 0.135 | ||
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.135 | ||
| WAC | WW domain containing adaptor with coiled-coil | 0.135 | ||
| TROVE2 | TROVE domain family, member 2 | 0.134 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.134 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.134 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.134 | ||
| RNF38 | ring finger protein 38 | 0.134 | ||
| ACTN1 | actinin, alpha 1 | 0.134 | Worm | |
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.133 | ||
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.133 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.132 | ||
| CP110 | CP110 protein | 0.132 | ||
| SPC25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.132 | ||
| OXSR1 | oxidative-stress responsive 1 | 0.132 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.132 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.131 | ||
| NCK2 | NCK adaptor protein 2 | 0.131 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.131 | ||
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.131 | ||
| PCM1 | pericentriolar material 1 | 0.131 | ||
| CDYL | chromodomain protein, Y-like | 0.131 | ||
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.131 | ||
| CHMP1A | chromatin modifying protein 1A | 0.131 | ||
| RPN1 | ribophorin I | 0.130 | ||
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.130 | ||
| TFDP1 | transcription factor Dp-1 | 0.130 | ||
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.130 | ||
| RAB14 | RAB14, member RAS oncogene family | 0.130 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.130 | ||
| AGAP7 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 7 | 0.129 | Human | |
| ZYG11B | zyg-11 homolog B (C. elegans) | 0.129 | ||
| TRIM33 | tripartite motif containing 33 | 0.129 | Human | |
| TPP1 | tripeptidyl peptidase I | 0.128 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.128 | ||
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.127 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.127 | Human Mouse Fly | |
| DHPS | deoxyhypusine synthase | 0.127 | ||
| TXN | thioredoxin | 0.127 | ||
| SOCS6 | suppressor of cytokine signaling 6 | 0.127 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.127 | ||
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.127 | ||
| SEC24B | SEC24 family, member B (S. cerevisiae) | 0.127 | ||
| USP8 | ubiquitin specific peptidase 8 | 0.127 | Yeast | |
| ZNF263 | zinc finger protein 263 | 0.126 | ||
| BTBD10 | BTB (POZ) domain containing 10 | 0.126 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.126 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.126 | Human | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.126 | Human | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.125 | ||
| WEE1 | WEE1 homolog (S. pombe) | 0.125 | ||
| LIMK1 | LIM domain kinase 1 | 0.125 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.124 | ||
| CCND1 | cyclin D1 | 0.124 | ||
| MED1 | mediator complex subunit 1 | 0.124 | ||
| MAP1A | microtubule-associated protein 1A | 0.124 | ||
| CD2 | CD2 molecule | 0.124 | ||
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.123 | ||
| TRIM23 | tripartite motif containing 23 | 0.123 | ||
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.123 | ||
| PJA1 | praja ring finger 1 | 0.123 | Mouse | |
| KRT15 | keratin 15 | 0.123 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.122 | ||
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.122 | ||
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.122 | ||
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 0.122 | ||
| KBTBD7 | kelch repeat and BTB (POZ) domain containing 7 | 0.122 | ||
| FAM175B | family with sequence similarity 175, member B | 0.122 | ||
| TRIM8 | tripartite motif containing 8 | 0.121 | Human Yeast | |
| TLK2 | tousled-like kinase 2 | 0.121 | ||
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.121 | ||
| TUBB2C | tubulin, beta 2C | 0.121 | ||
| USP2 | ubiquitin specific peptidase 2 | 0.121 | Yeast Fly | |
| EEF2 | eukaryotic translation elongation factor 2 | 0.120 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.119 | ||
| E2F1 | E2F transcription factor 1 | 0.119 | ||
| STMN1 | stathmin 1 | 0.119 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.119 | ||
| MED15 | mediator complex subunit 15 | 0.118 | ||
| CANX | calnexin | 0.118 | ||
| ATG3 | ATG3 autophagy related 3 homolog (S. cerevisiae) | 0.118 | ||
| EID2B | EP300 interacting inhibitor of differentiation 2B | 0.117 | ||
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.117 | ||
| FEM1B | fem-1 homolog b (C. elegans) | 0.117 | ||
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.117 | ||
| MAP1B | microtubule-associated protein 1B | 0.116 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.116 | ||
| PRKCB | protein kinase C, beta | 0.116 | ||
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.116 | ||
| GFM1 | G elongation factor, mitochondrial 1 | 0.116 | ||
| FSTL1 | follistatin-like 1 | 0.115 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.115 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.115 | ||
| MTA3 | metastasis associated 1 family, member 3 | 0.115 | Human | |
| PIM1 | pim-1 oncogene | 0.115 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.115 | Mouse | |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.114 | ||
| CHMP4B | chromatin modifying protein 4B | 0.114 | ||
| RFWD3 | ring finger and WD repeat domain 3 | 0.114 | ||
| MYO10 | myosin X | 0.114 | ||
| TSC22D1 | TSC22 domain family, member 1 | 0.114 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.114 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.114 | ||
| ZMYND19 | zinc finger, MYND-type containing 19 | 0.114 | ||
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.114 | ||
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 0.114 | ||
| DERL2 | Der1-like domain family, member 2 | 0.113 | ||
| TMEM173 | transmembrane protein 173 | 0.113 | ||
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.113 | ||
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.112 | ||
| ATN1 | atrophin 1 | 0.112 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.112 | ||
| RANBP3 | RAN binding protein 3 | 0.112 | ||
| SSX4 | synovial sarcoma, X breakpoint 4 | 0.112 | ||
| CLTA | clathrin, light chain A | 0.112 | ||
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.112 | ||
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 0.111 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.111 | ||
| ADNP | activity-dependent neuroprotector homeobox | 0.111 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.111 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.111 | ||
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.111 | ||
| PNPLA2 | patatin-like phospholipase domain containing 2 | 0.111 | ||
| GATAD2B | GATA zinc finger domain containing 2B | 0.111 | ||
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.110 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.110 | ||
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.110 | Human | |
| GORAB | golgin, RAB6-interacting | 0.110 | ||
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.109 | ||
| USP18 | ubiquitin specific peptidase 18 | 0.109 | ||
| NKAP | NFKB activating protein | 0.109 | ||
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.109 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.109 | Human | |
| ARF4 | ADP-ribosylation factor 4 | 0.108 | ||
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.108 | Yeast | |
| RBL2 | retinoblastoma-like 2 (p130) | 0.108 | Human | |
| CSNK1E | casein kinase 1, epsilon | 0.108 | Mouse Fly | |
| TRIM41 | tripartite motif containing 41 | 0.108 | Human | |
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.108 | ||
| CHAC1 | ChaC, cation transport regulator homolog 1 (E. coli) | 0.108 | ||
| PHAX | phosphorylated adaptor for RNA export | 0.108 | ||
| N4BP1 | NEDD4 binding protein 1 | 0.108 | Mouse | |
| IFNGR1 | interferon gamma receptor 1 | 0.107 | ||
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.107 | Rat | |
| INO80 | INO80 homolog (S. cerevisiae) | 0.107 | ||
| RACGAP1 | Rac GTPase activating protein 1 | 0.107 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.106 | ||
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.106 | ||
| TGFB2 | transforming growth factor, beta 2 | 0.106 | ||
| EIF5 | eukaryotic translation initiation factor 5 | 0.106 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.106 | ||
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.106 | ||
| AXIN2 | axin 2 | 0.106 | Human | |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.105 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.105 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.105 | ||
| MAGEA12 | melanoma antigen family A, 12 | 0.105 | Human | |
| HOOK3 | hook homolog 3 (Drosophila) | 0.105 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.105 | ||
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.105 | ||
| OPA1 | optic atrophy 1 (autosomal dominant) | 0.104 | Worm | |
| ACVR1B | activin A receptor, type IB | 0.104 | Worm | |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.104 | ||
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.104 | ||
| NIF3L1 | NIF3 NGG1 interacting factor 3-like 1 (S. pombe) | 0.104 | ||
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 | 0.104 |