Homo sapiens

22 known processes

SASS6

spindle assembly 6 homolog (C. elegans)

(Aliases: FLJ22097,SAS6,SAS-6,MGC119440)

SASS6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axoneme assembly GO:0035082 3 0.906
cilium morphogenesis GO:0060271 75 0.821
neuronal stem cell division GO:0036445 1 0.782
neuroblast division GO:0055057 1 0.742
somatic stem cell division GO:0048103 1 0.712
cilium assembly GO:0042384 63 0.708
regulation of microtubule based process GO:0032886 74 0.635
centrosome organization GO:0051297 58 0.610
organelle assembly GO:0070925 176 0.575
microtubule cytoskeleton organization GO:0000226 176 0.530
regulation of cytoskeleton organization GO:0051493 177 0.511
microtubule organizing center organization GO:0031023 62 0.476
neural tube closure GO:0001843 3 0.473
neural tube formation GO:0001841 3 0.468
centriole replication GO:0007099 13 0.424
embryonic epithelial tube formation GO:0001838 4 0.423
mitotic cell cycle GO:0000278 326 0.374
microtubule based process GO:0007017 210 0.354
anatomical structure formation involved in morphogenesis GO:0048646 284 0.338
microtubule polymerization or depolymerization GO:0031109 37 0.330
centrosome cycle GO:0007098 32 0.322
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.309
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.303
mitotic cell cycle process GO:1903047 286 0.297
centrosome duplication GO:0051298 28 0.276
primary neural tube formation GO:0014020 3 0.265
chromosome segregation GO:0007059 114 0.259
regulation of transferase activity GO:0051338 355 0.253
cilium organization GO:0044782 68 0.241
regulation of protein serine threonine kinase activity GO:0071900 179 0.240
morphogenesis of embryonic epithelium GO:0016331 4 0.233
centriole assembly GO:0098534 14 0.223
cell projection assembly GO:0030031 126 0.223
positive regulation of cell cycle GO:0045787 140 0.221
mitotic nuclear division GO:0007067 119 0.217
cell cycle checkpoint GO:0000075 117 0.205
protein localization to centrosome GO:0071539 5 0.198
mitotic centrosome separation GO:0007100 1 0.190
cell division GO:0051301 168 0.183
negative regulation of mitotic cell cycle GO:0045930 102 0.173
spindle checkpoint GO:0031577 26 0.169
cellular component assembly involved in morphogenesis GO:0010927 73 0.166
negative regulation of protein complex disassembly GO:0043242 20 0.164
asymmetric neuroblast division GO:0055059 1 0.163
mitotic cell cycle phase transition GO:0044772 162 0.157
regulation of cell cycle process GO:0010564 266 0.157
embryonic heart tube morphogenesis GO:0003143 8 0.153
cellular component morphogenesis GO:0032989 314 0.153
anatomical structure homeostasis GO:0060249 100 0.151
positive regulation of transferase activity GO:0051347 227 0.146
cell projection organization GO:0030030 252 0.144
glycosyl compound catabolic process GO:1901658 413 0.134
smoothened signaling pathway GO:0007224 14 0.133
cell cycle phase transition GO:0044770 173 0.133
regulation of cell cycle GO:0051726 393 0.118
negative regulation of cell cycle process GO:0010948 121 0.115
protein localization to microtubule cytoskeleton GO:0072698 10 0.113
positive regulation of kinase activity GO:0033674 204 0.110
cell projection morphogenesis GO:0048858 129 0.109
organ morphogenesis GO:0009887 147 0.108
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.106
cellular protein complex assembly GO:0043623 188 0.105
negative regulation of programmed cell death GO:0043069 321 0.103
cell part morphogenesis GO:0032990 137 0.102
positive regulation of protein phosphorylation GO:0001934 313 0.102
asymmetric stem cell division GO:0098722 1 0.099
microtubule polymerization GO:0046785 18 0.098
mitotic cell cycle checkpoint GO:0007093 68 0.098
negative regulation of cell cycle phase transition GO:1901988 89 0.096
negative regulation of apoptotic process GO:0043066 316 0.093
nervous system development GO:0007399 293 0.092
purine ribonucleoside catabolic process GO:0046130 398 0.088
regulation of microtubule cytoskeleton organization GO:0070507 61 0.082
embryonic heart tube development GO:0035050 9 0.080
stem cell division GO:0017145 2 0.079
protein localization to organelle GO:0033365 280 0.078
nucleoside triphosphate metabolic process GO:0009141 422 0.078
regulation of mitotic cell cycle phase transition GO:1901990 118 0.075
tissue morphogenesis GO:0048729 96 0.073
regulation of kinase activity GO:0043549 314 0.071
regulation of cell cycle phase transition GO:1901987 126 0.070
cellular component disassembly GO:0022411 92 0.069
protein localization to cytoskeleton GO:0044380 11 0.066
ribonucleotide catabolic process GO:0009261 405 0.065
regulation of mitotic cell cycle GO:0007346 189 0.065
embryonic organ morphogenesis GO:0048562 24 0.065
tube morphogenesis GO:0035239 95 0.064
nucleoside phosphate catabolic process GO:1901292 412 0.064
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.063
nuclear division GO:0000280 128 0.062
positive regulation of phosphorylation GO:0042327 394 0.062
growth GO:0040007 202 0.062
neuroblast proliferation GO:0007405 4 0.061
purine nucleotide catabolic process GO:0006195 405 0.058
epithelium development GO:0060429 227 0.058
embryonic morphogenesis GO:0048598 85 0.057
macromolecular complex disassembly GO:0032984 60 0.056
cell morphogenesis GO:0000902 296 0.053
ribonucleoside monophosphate catabolic process GO:0009158 158 0.048
organophosphate catabolic process GO:0046434 430 0.048
double strand break repair GO:0006302 101 0.047
purine containing compound catabolic process GO:0072523 411 0.047
central nervous system development GO:0007417 123 0.046
cellular response to dna damage stimulus GO:0006974 379 0.046
regulation of centrosome duplication GO:0010824 14 0.045
meiotic chromosome segregation GO:0045132 4 0.044
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.043
positive regulation of protein kinase activity GO:0045860 190 0.042
ribonucleoside catabolic process GO:0042454 406 0.042
head development GO:0060322 108 0.041
heart looping GO:0001947 7 0.040
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.039
protein polymerization GO:0051258 71 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
mitotic spindle checkpoint GO:0071174 18 0.039
regulation of protein depolymerization GO:1901879 22 0.039
regulation of protein kinase activity GO:0045859 289 0.039
meiosis i GO:0007127 4 0.038
cellular macromolecular complex assembly GO:0034622 324 0.037
spindle assembly GO:0051225 29 0.035
regulation of cell division GO:0051302 116 0.035
embryonic organ development GO:0048568 36 0.034
specification of symmetry GO:0009799 16 0.034
multicellular organismal aging GO:0010259 3 0.034
nucleoside monophosphate catabolic process GO:0009125 159 0.034
determination of left right symmetry GO:0007368 11 0.033
heart morphogenesis GO:0003007 48 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.032
organelle fission GO:0048285 149 0.031
cardiovascular system development GO:0072358 262 0.030
positive regulation of gtpase activity GO:0043547 166 0.030
centriole centriole cohesion GO:0010457 8 0.030
circulatory system development GO:0072359 262 0.029
epithelial tube morphogenesis GO:0060562 38 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.028
forebrain development GO:0030900 26 0.028
spindle organization GO:0007051 53 0.027
cytoplasmic transport GO:0016482 379 0.027
maintenance of location GO:0051235 112 0.026
positive regulation of organelle organization GO:0010638 195 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.025
regeneration GO:0031099 4 0.025
centrosome separation GO:0051299 3 0.024
regulation of nucleoside metabolic process GO:0009118 209 0.024
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.024
response to abiotic stimulus GO:0009628 336 0.024
determination of bilateral symmetry GO:0009855 15 0.024
determination of heart left right asymmetry GO:0061371 8 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
mitotic spindle organization GO:0007052 27 0.023
double strand break repair via homologous recombination GO:0000724 50 0.023
neuron cellular homeostasis GO:0070050 3 0.023
atp metabolic process GO:0046034 176 0.023
protein complex disassembly GO:0043241 52 0.023
negative regulation of cellular component organization GO:0051129 235 0.022
post embryonic development GO:0009791 2 0.022
protein catabolic process GO:0030163 325 0.022
negative regulation of protein depolymerization GO:1901880 17 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
spermatid differentiation GO:0048515 4 0.022
tube development GO:0035295 125 0.022
vesicle mediated transport GO:0016192 371 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
spermatid development GO:0007286 4 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
morphogenesis of an epithelium GO:0002009 60 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
determination of adult lifespan GO:0008340 2 0.021
female gamete generation GO:0007292 2 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
microtubule depolymerization GO:0007019 18 0.021
regulation of microtubule depolymerization GO:0031114 12 0.020
rho protein signal transduction GO:0007266 26 0.020
brain development GO:0007420 97 0.020
regulation of protein complex disassembly GO:0043244 28 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
protein depolymerization GO:0051261 30 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
cellular ketone metabolic process GO:0042180 80 0.019
response to cytokine GO:0034097 232 0.019
protein processing GO:0016485 226 0.018
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.018
protein targeting GO:0006605 187 0.017
negative regulation of cytoskeleton organization GO:0051494 45 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
regulation of protein localization GO:0032880 296 0.017
single organism cellular localization GO:1902580 332 0.017
negative regulation of cell death GO:0060548 345 0.017
regulation of protein transport GO:0051223 213 0.017
apoptotic signaling pathway GO:0097190 268 0.017
protein ubiquitination GO:0016567 314 0.016
negative regulation of cell cycle GO:0045786 193 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
protein maturation GO:0051604 233 0.016
recombinational repair GO:0000725 50 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
regulation of organelle assembly GO:1902115 40 0.016
pattern specification process GO:0007389 43 0.016
response to radiation GO:0009314 151 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
oxidation reduction process GO:0055114 396 0.016
cellular protein complex disassembly GO:0043624 36 0.016
regulation of protein stability GO:0031647 87 0.016
lipid metabolic process GO:0006629 381 0.016
cdc42 protein signal transduction GO:0032488 4 0.015
negative regulation of protein processing GO:0010955 142 0.015
cellular response to ionizing radiation GO:0071479 32 0.015
wnt signaling pathway GO:0016055 156 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
regulation of cellular response to stress GO:0080135 244 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
tissue regeneration GO:0042246 3 0.015
protein localization to nucleus GO:0034504 136 0.014
positive regulation of transport GO:0051050 336 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
intracellular protein transport GO:0006886 270 0.014
nucleoside catabolic process GO:0009164 408 0.014
oogenesis GO:0048477 2 0.014
maintenance of location in cell GO:0051651 62 0.014
regulation of centrosome cycle GO:0046605 15 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
blastocyst development GO:0001824 3 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
dna repair GO:0006281 198 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
heart development GO:0007507 95 0.013
negative regulation of protein modification process GO:0031400 200 0.013
amine metabolic process GO:0009308 44 0.013
protein import GO:0017038 130 0.013
actin filament based process GO:0030029 224 0.013
dna replication GO:0006260 116 0.013
dna conformation change GO:0071103 113 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
regulation of gtpase activity GO:0043087 180 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
regulation of proteolysis GO:0030162 293 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
rna processing GO:0006396 255 0.012
embryo development GO:0009790 123 0.012
rna splicing GO:0008380 131 0.012
negative regulation of immune system process GO:0002683 136 0.012
multi organism cellular process GO:0044764 156 0.012
cellular amino acid metabolic process GO:0006520 116 0.012
cellular amine metabolic process GO:0044106 41 0.012
oocyte development GO:0048599 1 0.012
actin filament based movement GO:0030048 17 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
single organism reproductive process GO:0044702 98 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
sister chromatid segregation GO:0000819 54 0.012
interspecies interaction between organisms GO:0044419 156 0.011
actin mediated cell contraction GO:0070252 12 0.011
chromosome separation GO:0051304 23 0.011
nucleotide catabolic process GO:0009166 408 0.011
regulation of intracellular transport GO:0032386 195 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
histone modification GO:0016570 251 0.011
mitotic sister chromatid segregation GO:0000070 53 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
negative regulation of transferase activity GO:0051348 124 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of double strand break repair via homologous recombination GO:0010569 11 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
nuclear transport GO:0051169 179 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
protein deubiquitination GO:0016579 79 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
positive regulation of cellular component organization GO:0051130 376 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
microtubule bundle formation GO:0001578 15 0.010
chordate embryonic development GO:0043009 34 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of dna replication GO:0006275 68 0.010
regulation of actin filament based process GO:0032970 141 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010

SASS6 disease predictions

Disease DO term ID Size Probability Func Analog Org
microcephaly DOID:10907 6 0.539
physical disorder DOID:0080015 41 0.539
congenital nervous system abnormality DOID:2490 21 0.539
immune system disease DOID:2914 155 0.061
hematopoietic system disease DOID:74 100 0.033
disease of cellular proliferation DOID:14566 174 0.023
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
disease of metabolism DOID:0014667 295 0.012
seckel syndrome DOID:0050569 5 0.010
blood coagulation disease DOID:1247 21 0.010