Homo sapiens

93 known processes

GZMA

granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

(Aliases: CTLA3,HFSP)

GZMA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nuclease activity GO:0032074 2 0.367
immune system development GO:0002520 195 0.346
leukocyte activation GO:0045321 164 0.344
cell activation GO:0001775 213 0.312
immune response GO:0006955 307 0.283
negative regulation of endodeoxyribonuclease activity GO:0032078 1 0.278
defense response GO:0006952 315 0.277
phagocytosis recognition GO:0006910 3 0.273
response to biotic stimulus GO:0009607 276 0.261
regulation of immune response GO:0050776 201 0.249
t cell activation GO:0042110 99 0.242
response to other organism GO:0051707 261 0.215
positive regulation of apoptotic process GO:0043065 246 0.213
regulation of camp metabolic process GO:0030814 52 0.206
positive regulation of cytokine production GO:0001819 167 0.201
hemopoiesis GO:0030097 180 0.186
lymphocyte activation GO:0046649 133 0.183
cytokine production GO:0001816 247 0.159
Human
interleukin 1 biosynthetic process GO:0042222 2 0.156
Human
secretion by cell GO:0032940 226 0.153
negative regulation of cell proliferation GO:0008285 228 0.139
positive regulation of programmed cell death GO:0043068 249 0.131
response to cytokine GO:0034097 232 0.127
positive regulation of developmental process GO:0051094 314 0.119
hematopoietic or lymphoid organ development GO:0048534 186 0.118
positive regulation of immune system process GO:0002684 283 0.118
cell chemotaxis GO:0060326 112 0.106
immune response regulating signaling pathway GO:0002764 97 0.104
regulation of secretion by cell GO:1903530 177 0.098
positive regulation of transport GO:0051050 336 0.098
regulation of cellular component movement GO:0051270 334 0.097
leukocyte differentiation GO:0002521 98 0.096
cytokine mediated signaling pathway GO:0019221 109 0.096
positive regulation of cell death GO:0010942 263 0.089
positive regulation of hydrolase activity GO:0051345 331 0.088
myeloid cell differentiation GO:0030099 117 0.088
eosinophil mediated immunity GO:0002447 2 0.085
immune effector process GO:0002252 159 0.085
secretion GO:0046903 254 0.084
positive regulation of cell differentiation GO:0045597 211 0.081
cellular amino acid metabolic process GO:0006520 116 0.080
post embryonic development GO:0009791 2 0.080
immune response activating signal transduction GO:0002757 90 0.079
response to external biotic stimulus GO:0043207 261 0.078
regulation of cytokine production GO:0001817 232 0.077
cell adhesion GO:0007155 325 0.076
positive regulation of secretion GO:0051047 116 0.075
negative regulation of deoxyribonuclease activity GO:0032076 1 0.071
regulation of vesicle mediated transport GO:0060627 130 0.071
positive regulation of cellular component organization GO:0051130 376 0.070
cell killing GO:0001906 34 0.069
purine ribonucleoside catabolic process GO:0046130 398 0.067
positive regulation of immune response GO:0050778 159 0.066
reactive nitrogen species metabolic process GO:2001057 3 0.065
activation of immune response GO:0002253 114 0.065
regulation of cell cycle GO:0051726 393 0.062
vesicle mediated transport GO:0016192 371 0.061
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.059
regulation of cell differentiation GO:0045595 393 0.058
i kappab kinase nf kappab signaling GO:0007249 166 0.058
g protein coupled receptor signaling pathway GO:0007186 207 0.058
regulation of establishment of protein localization GO:0070201 242 0.057
regulation of secretion GO:0051046 194 0.057
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.056
leukocyte mediated immunity GO:0002443 59 0.055
gtp catabolic process GO:0006184 237 0.054
camp metabolic process GO:0046058 61 0.054
purine nucleoside catabolic process GO:0006152 398 0.053
amine metabolic process GO:0009308 44 0.052
innate immune response GO:0045087 178 0.052
cell development GO:0048468 328 0.052
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.051
regulation of nucleotide metabolic process GO:0006140 269 0.051
glycosyl compound catabolic process GO:1901658 413 0.051
cellular ketone metabolic process GO:0042180 80 0.051
rho protein signal transduction GO:0007266 26 0.049
nucleoside triphosphate catabolic process GO:0009143 394 0.048
negative regulation of programmed cell death GO:0043069 321 0.048
regulation of intracellular transport GO:0032386 195 0.048
positive regulation of cellular amine metabolic process GO:0033240 7 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.048
ras protein signal transduction GO:0007265 73 0.047
regulation of anatomical structure morphogenesis GO:0022603 286 0.047
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.046
cellular response to cytokine stimulus GO:0071345 181 0.046
regulation of defense response GO:0031347 154 0.046
blood coagulation GO:0007596 76 0.045
regulation of cell motility GO:2000145 299 0.045
ribonucleoside triphosphate metabolic process GO:0009199 412 0.045
cellular amine metabolic process GO:0044106 41 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
cation transport GO:0006812 331 0.045
negative regulation of apoptotic process GO:0043066 316 0.045
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.044
ribonucleotide catabolic process GO:0009261 405 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.044
purine nucleotide catabolic process GO:0006195 405 0.044
multicellular organismal aging GO:0010259 3 0.044
positive regulation of innate immune response GO:0045089 79 0.044
single organismal cell cell adhesion GO:0016337 148 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
negative regulation of cell death GO:0060548 345 0.043
positive regulation of defense response GO:0031349 87 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.042
negative regulation of t cell cytokine production GO:0002725 4 0.041
cytoplasmic transport GO:0016482 379 0.041
regulation of cell migration GO:0030334 289 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
determination of adult lifespan GO:0008340 2 0.039
small gtpase mediated signal transduction GO:0007264 78 0.039
reactive oxygen species metabolic process GO:0072593 75 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.038
positive regulation of secretion by cell GO:1903532 108 0.038
response to oxygen containing compound GO:1901700 369 0.038
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
lymphocyte mediated immunity GO:0002449 48 0.037
cellular homeostasis GO:0019725 196 0.037
nucleoside catabolic process GO:0009164 408 0.037
adaptive immune response GO:0002250 49 0.037
taxis GO:0042330 157 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.037
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.036
intracellular protein transport GO:0006886 270 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
regulation of dna metabolic process GO:0051052 153 0.036
negative regulation of hydrolase activity GO:0051346 182 0.035
organonitrogen compound biosynthetic process GO:1901566 200 0.035
positive regulation of cell proliferation GO:0008284 301 0.035
purine ribonucleotide catabolic process GO:0009154 404 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
regulation of cytokine secretion GO:0050707 57 0.034
purinergic nucleotide receptor signaling pathway GO:0035590 4 0.034
biological adhesion GO:0022610 331 0.034
defense response to other organism GO:0098542 129 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.033
extrinsic apoptotic signaling pathway GO:0097191 119 0.033
regulation of leukocyte mediated immunity GO:0002703 38 0.033
regulation of cell activation GO:0050865 125 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.032
regulation of immune effector process GO:0002697 91 0.032
regulation of protein localization GO:0032880 296 0.032
positive regulation of phosphorylation GO:0042327 394 0.032
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.031
negative regulation of dna metabolic process GO:0051053 57 0.031
regulation of cell cycle process GO:0010564 266 0.031
nucleotide catabolic process GO:0009166 408 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
apoptotic signaling pathway GO:0097190 268 0.030
actin filament based process GO:0030029 224 0.030
positive regulation of catabolic process GO:0009896 310 0.030
response to abiotic stimulus GO:0009628 336 0.030
ribonucleoside catabolic process GO:0042454 406 0.029
positive regulation of cytokine secretion GO:0050715 42 0.029
actin filament polymerization GO:0030041 45 0.029
nervous system development GO:0007399 293 0.029
muscle cell proliferation GO:0033002 35 0.029
organophosphate catabolic process GO:0046434 430 0.029
divalent inorganic cation transport GO:0072511 158 0.029
positive regulation of cell cycle process GO:0090068 106 0.029
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.028
regulation of peptidase activity GO:0052547 180 0.028
regulation of mononuclear cell proliferation GO:0032944 65 0.028
eosinophil activation involved in immune response GO:0002278 2 0.028
response to tumor necrosis factor GO:0034612 76 0.028
regulation of nucleotide catabolic process GO:0030811 205 0.028
endocytosis GO:0006897 159 0.028
purine containing compound catabolic process GO:0072523 411 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.028
system process GO:0003008 349 0.028
single organism cellular localization GO:1902580 332 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
positive regulation of cell migration GO:0030335 172 0.027
activation of innate immune response GO:0002218 55 0.027
negative regulation of cell cycle GO:0045786 193 0.027
lymphocyte proliferation GO:0046651 70 0.027
regulation of binding GO:0051098 111 0.027
interspecies interaction between organisms GO:0044419 156 0.027
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.027
mononuclear cell proliferation GO:0032943 71 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
generation of neurons GO:0048699 152 0.026
protein secretion GO:0009306 98 0.026
positive regulation of leukocyte differentiation GO:1902107 37 0.026
protein catabolic process GO:0030163 325 0.026
regulation of rho protein signal transduction GO:0035023 79 0.026
cellular metal ion homeostasis GO:0006875 146 0.026
cell projection organization GO:0030030 252 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
regulation of protein secretion GO:0050708 86 0.026
receptor metabolic process GO:0043112 81 0.026
positive regulation of phospholipase activity GO:0010518 22 0.026
positive regulation of protein transport GO:0051222 135 0.025
cellular protein catabolic process GO:0044257 261 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.025
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.025
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.025
membrane organization GO:0061024 292 0.025
oogenesis GO:0048477 2 0.025
cell morphogenesis GO:0000902 296 0.024
regulation of multi organism process GO:0043900 157 0.024
cellular cation homeostasis GO:0030003 163 0.024
negative regulation of developmental process GO:0051093 247 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
regulation of response to external stimulus GO:0032101 222 0.024
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.024
regulation of body fluid levels GO:0050878 99 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
regulation of protein transport GO:0051223 213 0.024
negative regulation of cell differentiation GO:0045596 171 0.023
negative regulation of dna catabolic process GO:1903625 2 0.023
neuromuscular junction development GO:0007528 3 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
actin cytoskeleton organization GO:0030036 207 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
cardiovascular system development GO:0072358 262 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
lipid metabolic process GO:0006629 381 0.023
peptidyl tyrosine modification GO:0018212 170 0.023
protein processing GO:0016485 226 0.023
response to lipid GO:0033993 206 0.022
mitotic cell cycle process GO:1903047 286 0.022
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
regulation of locomotion GO:0040012 329 0.022
cell cell recognition GO:0009988 4 0.022
cellular divalent inorganic cation homeostasis GO:0072503 128 0.022
regulation of leukocyte differentiation GO:1902105 61 0.022
regulation of hormone levels GO:0010817 125 0.022
regulation of camp mediated signaling GO:0043949 13 0.022
t cell proliferation GO:0042098 45 0.022
negative regulation of catabolic process GO:0009895 104 0.022
regulation of cell adhesion GO:0030155 166 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
regulation of proteolysis GO:0030162 293 0.021
cellular chemical homeostasis GO:0055082 180 0.021
follicle stimulating hormone secretion GO:0046884 3 0.021
mature dendritic cell differentiation GO:0097029 2 0.021
regulation of reactive oxygen species metabolic process GO:2000377 41 0.021
positive regulation of leukocyte chemotaxis GO:0002690 38 0.021
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
divalent inorganic cation homeostasis GO:0072507 136 0.021
positive regulation of proteolysis GO:0045862 142 0.021
segmentation GO:0035282 4 0.021
response to virus GO:0009615 126 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
cellular component morphogenesis GO:0032989 314 0.020
divalent metal ion transport GO:0070838 152 0.020
positive regulation of locomotion GO:0040017 186 0.020
single organism cell adhesion GO:0098602 179 0.020
positive regulation of cell cycle GO:0045787 140 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
lymphocyte differentiation GO:0030098 35 0.020
innate immune response activating signal transduction GO:0002758 48 0.020
negative regulation of immune system process GO:0002683 136 0.020
blood vessel development GO:0001568 172 0.020
gtp metabolic process GO:0046039 239 0.020
chemotaxis GO:0006935 157 0.020
maintenance of location GO:0051235 112 0.020
sequestering of calcium ion GO:0051208 17 0.020
hormone secretion GO:0046879 65 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.019
sequestering of metal ion GO:0051238 24 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.019
metal ion transport GO:0030001 272 0.019
positive regulation of leukocyte mediated immunity GO:0002705 24 0.019
wound healing GO:0042060 115 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
regulation of astrocyte chemotaxis GO:2000458 1 0.019
response to bacterium GO:0009617 144 0.019
protein maturation GO:0051604 233 0.019
leukocyte mediated cytotoxicity GO:0001909 27 0.019
regulation of behavior GO:0050795 82 0.019
regulation of innate immune response GO:0045088 97 0.019
cellular ion homeostasis GO:0006873 168 0.019
angiogenesis GO:0001525 147 0.019
positive regulation of organelle organization GO:0010638 195 0.019
positive regulation of myeloid cell differentiation GO:0045639 39 0.019
positive regulation of immune effector process GO:0002699 40 0.019
metal ion homeostasis GO:0055065 169 0.018
positive regulation of protein secretion GO:0050714 60 0.018
defense response to bacterium GO:0042742 63 0.018
cellular response to tumor necrosis factor GO:0071356 63 0.018
pattern recognition receptor signaling pathway GO:0002221 48 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
cellular response to external stimulus GO:0071496 111 0.018
single organism membrane organization GO:0044802 268 0.018
dephosphorylation GO:0016311 209 0.018
positive regulation of camp metabolic process GO:0030816 41 0.018
regulation of lymphocyte mediated immunity GO:0002706 33 0.018
platelet activation GO:0030168 44 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
interleukin 1 beta biosynthetic process GO:0050720 2 0.018
Human
protein oligomerization GO:0051259 173 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
epithelium development GO:0060429 227 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
cellular protein complex assembly GO:0043623 188 0.017
dna catabolic process GO:0006308 49 0.017
calcium ion transport GO:0006816 147 0.017
response to growth factor GO:0070848 205 0.017
protein targeting GO:0006605 187 0.017
cytokine secretion GO:0050663 64 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
regulation of response to wounding GO:1903034 101 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
cell cell signaling GO:0007267 155 0.017
behavior GO:0007610 112 0.017
regulation of gtpase activity GO:0043087 180 0.017
receptor internalization GO:0031623 43 0.017
regulation of camp biosynthetic process GO:0030817 45 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
cellular response to lipid GO:0071396 127 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.017
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.017
cell fate determination GO:0001709 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
positive regulation of transferase activity GO:0051347 227 0.016
regulation of cell division GO:0051302 116 0.016
blood vessel morphogenesis GO:0048514 162 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
circulatory system development GO:0072359 262 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
regulation of leukocyte activation GO:0002694 115 0.016
positive regulation of cell killing GO:0031343 19 0.016
negative regulation of angiogenesis GO:0016525 39 0.016
positive regulation of lipase activity GO:0060193 28 0.016
negative regulation of binding GO:0051100 57 0.016
negative regulation of cell motility GO:2000146 104 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
cell type specific apoptotic process GO:0097285 125 0.016
response to organic cyclic compound GO:0014070 204 0.016
regulation of calcium ion transport into cytosol GO:0010522 33 0.015
regulation of dna binding GO:0051101 37 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
sensory perception of pain GO:0019233 4 0.015
regulation of myeloid cell differentiation GO:0045637 81 0.015
interleukin 1 production GO:0032612 26 0.015
Human
t cell selection GO:0045058 4 0.015
cell part morphogenesis GO:0032990 137 0.015
spermatid development GO:0007286 4 0.015
leukocyte migration GO:0050900 107 0.015
embryonic viscerocranium morphogenesis GO:0048703 1 0.015
transmembrane transport GO:0055085 399 0.015
pericardium development GO:0060039 2 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
response to wounding GO:0009611 168 0.015
regulation of leukocyte proliferation GO:0070663 67 0.015
neurogenesis GO:0022008 169 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
oocyte development GO:0048599 1 0.015
hemostasis GO:0007599 76 0.014
inflammatory response GO:0006954 79 0.014
regulation of protein complex assembly GO:0043254 147 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
positive regulation of leukocyte activation GO:0002696 80 0.014
regulation of cell development GO:0060284 161 0.014
peripheral nervous system development GO:0007422 2 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
cellular response to ammonium ion GO:0071242 4 0.014
cell cycle phase transition GO:0044770 173 0.014
vasculature development GO:0001944 181 0.014
regeneration GO:0031099 4 0.014
regulation of protein maturation GO:1903317 150 0.014
negative regulation of protein processing GO:0010955 142 0.014
neuron development GO:0048666 113 0.014
endomembrane system organization GO:0010256 196 0.014
mitotic cell cycle GO:0000278 326 0.014
calcium ion homeostasis GO:0055074 122 0.014
regulation of chemotaxis GO:0050920 74 0.014
antigen receptor mediated signaling pathway GO:0050851 38 0.014
growth GO:0040007 202 0.014
glial cell migration GO:0008347 4 0.014
positive regulation of cell activation GO:0050867 81 0.014
viral process GO:0016032 146 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
defense response to virus GO:0051607 71 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
protein localization to membrane GO:0072657 160 0.014
microtubule based process GO:0007017 210 0.014
viral life cycle GO:0019058 132 0.014
rhythmic behavior GO:0007622 2 0.014
negative regulation of cell migration GO:0030336 102 0.014
cation homeostasis GO:0055080 189 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
positive regulation of cell motility GO:2000147 177 0.013
establishment of t cell polarity GO:0001768 2 0.013
regulation of myeloid leukocyte differentiation GO:0002761 39 0.013
regulation of kinase activity GO:0043549 314 0.013
negative regulation of proteolysis GO:0045861 132 0.013
cellular lipid metabolic process GO:0044255 303 0.013
spermatid differentiation GO:0048515 4 0.013
response to radiation GO:0009314 151 0.013
positive regulation of ion transport GO:0043270 87 0.013
leukocyte proliferation GO:0070661 74 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
protein autophosphorylation GO:0046777 123 0.013
neuron differentiation GO:0030182 138 0.013
response to extracellular stimulus GO:0009991 85 0.013
positive regulation of cell development GO:0010720 92 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
regulation of viral process GO:0050792 103 0.013
response to hormone GO:0009725 175 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
regulation of protein processing GO:0070613 150 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.013
protein localization to nucleus GO:0034504 136 0.013
regulation of eosinophil activation GO:1902566 2 0.013
eosinophil degranulation GO:0043308 2 0.013
nuclear transport GO:0051169 179 0.012
leukocyte chemotaxis GO:0030595 76 0.012
mapk cascade GO:0000165 288 0.012
negative regulation of vasculature development GO:1901343 43 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of nuclease activity GO:0032069 11 0.012
positive regulation of homeostatic process GO:0032846 47 0.012
regulation of cellular component size GO:0032535 82 0.012
regulation of protein kinase activity GO:0045859 289 0.012
cell cycle arrest GO:0007050 71 0.012
activation of cysteine type endopeptidase activity GO:0097202 57 0.012
regulation of metal ion transport GO:0010959 120 0.012
protein targeting to nucleus GO:0044744 104 0.012
chemical homeostasis GO:0048878 306 0.012
cellular biogenic amine metabolic process GO:0006576 34 0.012
compound eye development GO:0048749 1 0.012
protein polymerization GO:0051258 71 0.012
myeloid leukocyte activation GO:0002274 34 0.012
mating GO:0007618 1 0.012
skeletal system development GO:0001501 79 0.012
female gamete generation GO:0007292 2 0.012
regulation of anatomical structure size GO:0090066 101 0.012
leukocyte activation involved in immune response GO:0002366 30 0.012
embryonic morphogenesis GO:0048598 85 0.012
regulation of lymphocyte proliferation GO:0050670 64 0.012
protein import into nucleus GO:0006606 104 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of transferase activity GO:0051338 355 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.012
carbohydrate metabolic process GO:0005975 207 0.012
regulation of angiogenesis GO:0045765 92 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.011
autophagy GO:0006914 88 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
positive regulation of macrophage chemotaxis GO:0010759 3 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
inflammatory cell apoptotic process GO:0006925 3 0.011
receptor mediated endocytosis GO:0006898 84 0.011
cell projection assembly GO:0030031 126 0.011
cellular response to interleukin 1 GO:0071347 35 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
regulation of actin filament based process GO:0032970 141 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
cell growth GO:0016049 160 0.011
hormone transport GO:0009914 68 0.011
actin filament organization GO:0007015 128 0.011
regulation of actin filament length GO:0030832 56 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
ribonucleotide biosynthetic process GO:0009260 81 0.011
jak stat cascade GO:0007259 46 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
regulation of mapk cascade GO:0043408 262 0.011
post embryonic organ development GO:0048569 1 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011

GZMA disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.060
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
hematopoietic system disease DOID:74 100 0.014
musculoskeletal system disease DOID:17 223 0.013
organ system cancer DOID:0050686 164 0.013