Process View
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "g protein coupled purinergic nucleotide receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.666 | ||
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.167 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.116 | ||
| ITK | IL2-inducible T-cell kinase | 0.115 | ||
| GIMAP4 | GTPase, IMAP family member 4 | 0.073 | ||
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.060 | ||
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.055 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.047 | ||
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.046 | ||
| EVI2A | ecotropic viral integration site 2A | 0.041 | ||
| GPR18 | G protein-coupled receptor 18 | 0.040 | ||
| CD2 | CD2 molecule | 0.038 | ||
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.035 | Human | |
| FYB | FYN binding protein | 0.034 | ||
| AIF1 | allograft inflammatory factor 1 | 0.033 | ||
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.032 | ||
| SELL | selectin L | 0.028 | ||
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.027 | ||
| BIN2 | bridging integrator 2 | 0.027 | ||
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4 | 0.026 | ||
| MNDA | myeloid cell nuclear differentiation antigen | 0.025 | ||
| CD96 | CD96 molecule | 0.025 | ||
| LY86 | lymphocyte antigen 86 | 0.025 | ||
| CD8A | CD8a molecule | 0.024 | ||
| GPR65 | G protein-coupled receptor 65 | 0.023 | ||
| THEMIS | thymocyte selection associated | 0.023 | ||
| CLEC4A | C-type lectin domain family 4, member A | 0.023 | ||
| RNASE6 | ribonuclease, RNase A family, k6 | 0.023 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.020 | ||
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.020 | ||
| GPR183 | G protein-coupled receptor 183 | 0.020 | ||
| CD86 | CD86 molecule | 0.019 | ||
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.018 | ||
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.018 | ||
| CYTIP | cytohesin 1 interacting protein | 0.018 | ||
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.017 | ||
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.017 | ||
| CCR2 | chemokine (C-C motif) receptor 2 | 0.017 | ||
| EVI2B | ecotropic viral integration site 2B | 0.016 | ||
| CD84 | CD84 molecule | 0.016 | ||
| CRTAM | cytotoxic and regulatory T cell molecule | 0.015 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.015 | ||
| ARHGAP15 | Rho GTPase activating protein 15 | 0.014 | ||
| TLR8 | toll-like receptor 8 | 0.013 | ||
| IFNG | interferon, gamma | 0.013 | ||
| RGS18 | regulator of G-protein signaling 18 | 0.013 | ||
| CD163 | CD163 molecule | 0.013 | ||
| ICOS | inducible T-cell co-stimulator | 0.013 | ||
| CYSLTR1 | cysteinyl leukotriene receptor 1 | 0.012 | ||
| CD1C | CD1c molecule | 0.012 | ||
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.012 | ||
| IPCEF1 | interaction protein for cytohesin exchange factors 1 | 0.011 | ||
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.011 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.010 | ||
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.010 | ||
| FGL2 | fibrinogen-like 2 | 0.010 | ||
| IRF8 | interferon regulatory factor 8 | 0.010 |