Homo sapiens

117 known processes

ADORA2A

adenosine A2a receptor

(Aliases: RDC8,hA2aR,ADORA2)

ADORA2A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 1.000
auditory behavior GO:0031223 4 1.000
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 1.000
negative regulation of amine transport GO:0051953 1 1.000
regulation of excretion GO:0044062 1 1.000
Rat
gabaergic neuron differentiation GO:0097154 1 0.999
camp biosynthetic process GO:0006171 47 0.999
sodium ion homeostasis GO:0055078 14 0.999
Rat
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.998
regulation of amine transport GO:0051952 5 0.998
Rat
circadian sleep wake cycle sleep GO:0050802 2 0.998
Rat
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.996
circadian sleep wake cycle GO:0042745 2 0.995
Rat
regulation of camp biosynthetic process GO:0030817 45 0.995
circadian sleep wake cycle process GO:0022410 2 0.994
Rat
regulation of camp metabolic process GO:0030814 52 0.985
regulation of catecholamine secretion GO:0050433 1 0.984
Rat
nucleoside phosphate biosynthetic process GO:1901293 109 0.983
cyclic nucleotide metabolic process GO:0009187 82 0.982
catecholamine transport GO:0051937 6 0.980
Rat
dopamine transport GO:0015872 5 0.965
regulation of synaptic transmission dopaminergic GO:0032225 4 0.965
cyclic nucleotide biosynthetic process GO:0009190 61 0.953
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.952
sensory perception of smell GO:0007608 2 0.946
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.938
Rat
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 6 0.927
negative regulation of blood pressure GO:0045776 3 0.923
catecholamine secretion GO:0050432 1 0.916
Rat
circadian behavior GO:0048512 2 0.915
Rat
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.914
positive regulation of sodium proton antiporter activity GO:0032417 3 0.906
positive regulation of catecholamine uptake involved in synaptic transmission GO:0051944 1 0.904
response to auditory stimulus GO:0010996 4 0.891
camp metabolic process GO:0046058 61 0.857
negative regulation of synaptic transmission GO:0050805 2 0.852
excretion GO:0007588 9 0.833
Rat
regulation of lyase activity GO:0051339 23 0.810
regulation of dopamine uptake involved in synaptic transmission GO:0051584 4 0.806
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.801
forebrain generation of neurons GO:0021872 3 0.794
organophosphate biosynthetic process GO:0090407 163 0.784
positive regulation of neurotransmitter uptake GO:0051582 1 0.781
positive regulation of neurotransmitter transport GO:0051590 1 0.776
Rat
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.774
substrate independent telencephalic tangential migration GO:0021826 0 0.749
multicellular organismal homeostasis GO:0048871 67 0.721
Zebrafish
positive regulation of ion transport GO:0043270 87 0.719
Rat
neuron neuron synaptic transmission GO:0007270 6 0.709
Mouse Rat
organic anion transport GO:0015711 103 0.701
Rat
lipid metabolic process GO:0006629 381 0.695
potassium ion transport GO:0006813 62 0.685
forebrain neuron differentiation GO:0021879 3 0.685
dopamine uptake GO:0090494 4 0.669
regulation of system process GO:0044057 101 0.664
Rat
dopamine uptake involved in synaptic transmission GO:0051583 4 0.658
muscle contraction GO:0006936 73 0.658
carbohydrate derivative biosynthetic process GO:1901137 207 0.654
sequestering of metal ion GO:0051238 24 0.646
positive regulation of protein phosphorylation GO:0001934 313 0.641
limbic system development GO:0021761 3 0.635
monovalent inorganic cation transport GO:0015672 128 0.620
monoamine transport GO:0015844 10 0.614
Rat
memory GO:0007613 3 0.613
anion transport GO:0006820 161 0.609
Rat
dephosphorylation GO:0016311 209 0.597
positive regulation of synaptic transmission GO:0050806 4 0.591
Mouse Rat
regulation of behavior GO:0050795 82 0.584
Rat
response to histamine GO:0034776 6 0.581
positive regulation of amine transport GO:0051954 2 0.574
Rat
purine ribonucleotide biosynthetic process GO:0009152 79 0.570
glycine import GO:0036233 1 0.567
negative regulation of secretion by cell GO:1903531 52 0.567
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.559
heart process GO:0003015 62 0.557
Zebrafish
mechanosensory behavior GO:0007638 4 0.553
regulation of body fluid levels GO:0050878 99 0.547
Rat
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 3 0.547
peptide secretion GO:0002790 51 0.544
long term memory GO:0007616 2 0.540
amine transport GO:0015837 7 0.540
Rat
nucleotide biosynthetic process GO:0009165 109 0.540
mapk cascade GO:0000165 288 0.540
regulation of cyclase activity GO:0031279 19 0.532
negative regulation of cell proliferation GO:0008285 228 0.525
Rat
muscle system process GO:0003012 81 0.517
calcium ion transmembrane transport GO:0070588 76 0.510
regulation of hormone secretion GO:0046883 57 0.497
regulation of calcium ion transport GO:0051924 79 0.483
Rat
acid secretion GO:0046717 12 0.481
Rat
icosanoid secretion GO:0032309 11 0.474
positive regulation of camp biosynthetic process GO:0030819 35 0.471
negative regulation of secretion GO:0051048 58 0.467
negative regulation of homeostatic process GO:0032845 59 0.466
smooth muscle contraction GO:0006939 14 0.458
synaptic transmission GO:0007268 61 0.456
Mouse Rat
regulation of potassium ion transport GO:0043266 24 0.454
negative regulation of cellular component movement GO:0051271 106 0.453
positive regulation of transferase activity GO:0051347 227 0.453
regulation of hormone levels GO:0010817 125 0.452
regulation of circadian rhythm GO:0042752 11 0.441
Rat
regulation of blood pressure GO:0008217 30 0.430
positive regulation of neural precursor cell proliferation GO:2000179 2 0.429
neurotransmitter uptake GO:0001504 5 0.421
amide transport GO:0042886 76 0.419
neuroblast proliferation GO:0007405 4 0.418
organonitrogen compound biosynthetic process GO:1901566 200 0.418
hormone secretion GO:0046879 65 0.415
sodium ion transport GO:0006814 61 0.414
regulation of metal ion transport GO:0010959 120 0.410
Rat
regulation of locomotion GO:0040012 329 0.402
Rat
regulation of nucleotide metabolic process GO:0006140 269 0.398
catecholamine uptake GO:0090493 4 0.396
response to decreased oxygen levels GO:0036293 96 0.387
negative regulation of ion transport GO:0043271 39 0.385
arachidonic acid secretion GO:0050482 7 0.382
locomotory behavior GO:0007626 1 0.381
Mouse Rat
regulation of cell migration GO:0030334 289 0.380
positive regulation of protein kinase activity GO:0045860 190 0.377
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.374
regulation of blood circulation GO:1903522 59 0.373
regulation of nucleotide biosynthetic process GO:0030808 50 0.370
regulation of receptor internalization GO:0002090 15 0.370
regulation of neuronal synaptic plasticity GO:0048168 1 0.367
rhythmic behavior GO:0007622 2 0.364
Rat
regulation of secretion by cell GO:1903530 177 0.356
Rat
forebrain neuron development GO:0021884 2 0.353
positive regulation of mapk cascade GO:0043410 190 0.353
activation of protein kinase activity GO:0032147 90 0.351
phospholipase c activating dopamine receptor signaling pathway GO:0060158 2 0.349
glycerophospholipid metabolic process GO:0006650 84 0.348
synaptic transmission glycinergic GO:0060012 1 0.348
regulation of systemic arterial blood pressure GO:0003073 19 0.347
negative regulation of cell migration GO:0030336 102 0.346
negative regulation of adenylate cyclase activity GO:0007194 5 0.341
positive regulation of cytokinesis GO:0032467 29 0.340
negative regulation of lipid catabolic process GO:0050995 9 0.337
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.337
sodium ion transmembrane transport GO:0035725 59 0.334
blood circulation GO:0008015 113 0.331
Zebrafish Rat
peptide transport GO:0015833 74 0.328
positive regulation of phosphorylation GO:0042327 394 0.327
behavioral response to ethanol GO:0048149 2 0.320
positive regulation of sodium ion transmembrane transporter activity GO:2000651 6 0.319
long term synaptic potentiation GO:0060291 1 0.318
regulation of heart contraction GO:0008016 50 0.318
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.312
positive regulation of cell division GO:0051781 59 0.308
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 1 0.306
ion homeostasis GO:0050801 230 0.303
Rat
regulation of neurotransmitter uptake GO:0051580 4 0.300
negative regulation of hormone secretion GO:0046888 15 0.298
associative learning GO:0008306 1 0.297
regulation of protein serine threonine kinase activity GO:0071900 179 0.297
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.296
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.295
regulation of protein kinase activity GO:0045859 289 0.292
Rat
ion transmembrane transport GO:0034220 338 0.292
positive regulation of adenylate cyclase activity GO:0045762 12 0.290
negative regulation of cell motility GO:2000146 104 0.285
icosanoid transport GO:0071715 11 0.284
activation of mapk activity GO:0000187 45 0.284
heart contraction GO:0060047 62 0.282
Zebrafish
response to axon injury GO:0048678 1 0.281
sensory perception of chemical stimulus GO:0007606 38 0.280
secretion by cell GO:0032940 226 0.279
Rat
chemical homeostasis GO:0048878 306 0.279
Rat
regulation of dephosphorylation GO:0035303 96 0.277
neurological system process GO:0050877 163 0.276
Rat
negative regulation of behavior GO:0048521 15 0.275
regulation of mapk cascade GO:0043408 262 0.274
sequestering of calcium ion GO:0051208 17 0.273
regulation of sensory perception of pain GO:0051930 3 0.273
metal ion homeostasis GO:0055065 169 0.269
Rat
regulation of neural precursor cell proliferation GO:2000177 4 0.265
positive regulation of transmembrane transport GO:0034764 41 0.264
negative regulation of circadian sleep wake cycle sleep GO:0042321 1 0.263
cyclic purine nucleotide metabolic process GO:0052652 60 0.258
regulation of neuroblast proliferation GO:1902692 3 0.256
purine containing compound biosynthetic process GO:0072522 88 0.252
regulation of ion transport GO:0043269 189 0.251
Rat
regulation of synaptic plasticity GO:0048167 3 0.249
Rat
negative regulation of transport GO:0051051 176 0.247
regulation of sensory perception GO:0051931 3 0.244
regulation of cellular component movement GO:0051270 334 0.243
sensory perception of pain GO:0019233 4 0.242
negative regulation of multicellular organismal process GO:0051241 317 0.241
regulation of protein secretion GO:0050708 86 0.237
Rat
positive regulation of secretion GO:0051047 116 0.233
Rat
circulatory system process GO:0003013 113 0.232
Zebrafish Rat
positive regulation of camp metabolic process GO:0030816 41 0.230
phosphatidylinositol metabolic process GO:0046488 53 0.229
cellular lipid metabolic process GO:0044255 303 0.227
regulation of homeostatic process GO:0032844 121 0.226
Rat
ribonucleotide biosynthetic process GO:0009260 81 0.225
regulation of synapse structural plasticity GO:0051823 2 0.221
regulation of cell motility GO:2000145 299 0.219
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.216
sensory perception GO:0007600 103 0.215
negative regulation of circadian rhythm GO:0042754 1 0.214
organic hydroxy compound transport GO:0015850 63 0.212
Rat
adult locomotory behavior GO:0008344 1 0.211
regulation of sodium ion transmembrane transport GO:1902305 23 0.210
growth hormone secretion GO:0030252 4 0.209
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.208
regulation of purine nucleotide metabolic process GO:1900542 264 0.207
signal release GO:0023061 70 0.207
Rat
vasodilation GO:0042311 4 0.206
Rat
regulation of peptide transport GO:0090087 62 0.203
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.202
regulation of circadian sleep wake cycle GO:0042749 2 0.201
Rat
regulation of cell cycle process GO:0010564 266 0.197
telencephalon cell migration GO:0022029 4 0.197
hormone transport GO:0009914 68 0.194
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.191
purine nucleotide biosynthetic process GO:0006164 84 0.191
response to hypoxia GO:0001666 96 0.190
positive regulation of nucleotide metabolic process GO:0045981 230 0.189
regulation of neurotransmitter transport GO:0051588 7 0.179
Rat
circadian rhythm GO:0007623 21 0.177
Rat
regulation of synaptic transmission GO:0050804 11 0.177
Mouse Rat
signal transduction by phosphorylation GO:0023014 297 0.172
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.172
renal system process involved in regulation of blood volume GO:0001977 4 0.169
subpallium development GO:0021544 2 0.166
lipid catabolic process GO:0016042 84 0.165
regulation of sodium ion transport GO:0002028 24 0.163
positive regulation of transport GO:0051050 336 0.162
Rat
positive regulation of map kinase activity GO:0043406 80 0.162
insulin secretion GO:0030073 39 0.160
nitrogen compound transport GO:0071705 191 0.160
Rat
regulation of map kinase activity GO:0043405 108 0.158
positive regulation of cellular component organization GO:0051130 376 0.155
response to cocaine GO:0042220 1 0.154
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.153
organic hydroxy compound metabolic process GO:1901615 147 0.153
regulation of cellular ketone metabolic process GO:0010565 50 0.153
regulation of sequestering of calcium ion GO:0051282 41 0.151
cytokinesis GO:0000910 96 0.150
vesicle mediated transport GO:0016192 371 0.148
negative regulation of lyase activity GO:0051350 7 0.148
positive regulation of synaptic transmission dopaminergic GO:0032226 1 0.144
positive regulation of peptide secretion GO:0002793 15 0.144
transmembrane transport GO:0055085 399 0.144
ribose phosphate biosynthetic process GO:0046390 82 0.143
calcium ion transport GO:0006816 147 0.142
Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.141
Rat
system process GO:0003008 349 0.137
Zebrafish Rat
negative regulation of catalytic activity GO:0043086 335 0.136
Rat
regulation of protein transport GO:0051223 213 0.134
Rat
negative regulation of phosphorus metabolic process GO:0010563 267 0.133
Rat
inorganic ion transmembrane transport GO:0098660 231 0.130
glycerolipid metabolic process GO:0046486 107 0.129
dopamine receptor signaling pathway GO:0007212 10 0.129
regulation of vesicle mediated transport GO:0060627 130 0.129
positive regulation of kinase activity GO:0033674 204 0.128
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 4 0.126
regulation of peptide hormone secretion GO:0090276 41 0.124
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.123
regulation of transmembrane transporter activity GO:0022898 74 0.123
cell morphogenesis GO:0000902 296 0.123
Rat
cation transport GO:0006812 331 0.123
Rat
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.122
Rat
visual behavior GO:0007632 2 0.122
regulation of peptide secretion GO:0002791 42 0.121
cation homeostasis GO:0055080 189 0.121
Rat
regulation of lipid catabolic process GO:0050994 23 0.121
positive regulation of secretion by cell GO:1903532 108 0.119
Rat
cellular ketone metabolic process GO:0042180 80 0.119
phospholipid metabolic process GO:0006644 99 0.118
lipid transport GO:0006869 90 0.118
regulation of establishment of protein localization GO:0070201 242 0.118
Rat
protein secretion GO:0009306 98 0.117
Rat
cell cell signaling GO:0007267 155 0.114
Mouse Rat
regulation of calcium ion transmembrane transport GO:1903169 28 0.114
negative regulation of protein transport GO:0051224 75 0.114
cellular component morphogenesis GO:0032989 314 0.113
Rat
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.113
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.113
wnt signaling pathway GO:0016055 156 0.113
response to nicotine GO:0035094 12 0.111
response to oxygen levels GO:0070482 100 0.110
positive regulation of cell cycle process GO:0090068 106 0.107
divalent inorganic cation transport GO:0072511 158 0.107
Rat
regulation of secretion GO:0051046 194 0.105
Rat
cellular ion homeostasis GO:0006873 168 0.103
regulation of voltage gated calcium channel activity GO:1901385 7 0.103
adaptation of signaling pathway GO:0023058 7 0.103
regulation of ion homeostasis GO:2000021 73 0.102
Rat
regulation of cellular amino acid metabolic process GO:0006521 6 0.101
positive regulation of sodium ion transmembrane transport GO:1902307 9 0.101
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 9 0.099
circadian regulation of gene expression GO:0032922 8 0.099
detection of stimulus GO:0051606 85 0.098
cellular cation homeostasis GO:0030003 163 0.097
regulation of membrane potential GO:0042391 95 0.095
Mouse Rat
positive regulation of transporter activity GO:0032411 32 0.095
negative regulation of catabolic process GO:0009895 104 0.095
regulation of cell cycle GO:0051726 393 0.095
negative regulation of sequestering of calcium ion GO:0051283 41 0.094
substrate independent telencephalic tangential interneuron migration GO:0021843 0 0.094
positive regulation of cell proliferation GO:0008284 301 0.094
response to abiotic stimulus GO:0009628 336 0.093
regulation of striated muscle contraction GO:0006942 37 0.092
regulation of receptor mediated endocytosis GO:0048259 32 0.092
negative regulation of ion transmembrane transport GO:0034766 26 0.091
response to alkaloid GO:0043279 20 0.091
Rat
g protein coupled receptor signaling pathway GO:0007186 207 0.090
regulation of response to external stimulus GO:0032101 222 0.089
Mouse Rat
negative regulation of protein secretion GO:0050709 29 0.089
negative regulation of dopamine receptor signaling pathway GO:0060160 1 0.089
erk1 and erk2 cascade GO:0070371 104 0.088
cellular calcium ion homeostasis GO:0006874 117 0.088
sleep GO:0030431 2 0.087
Rat
calcium ion transport into cytosol GO:0060402 48 0.087
purine ribonucleoside metabolic process GO:0046128 437 0.087
regulation of phosphatase activity GO:0010921 81 0.087
protein kinase b signaling GO:0043491 69 0.086
regulation of heart rate GO:0002027 38 0.086
response to nitrogen compound GO:1901698 184 0.085
Mouse Rat
regulation of blood vessel size GO:0050880 18 0.084
Rat
regulation of erk1 and erk2 cascade GO:0070372 99 0.083
rhythmic process GO:0048511 31 0.083
Rat
regulation of dopamine receptor signaling pathway GO:0060159 3 0.083
positive regulation of potassium ion transport GO:0043268 15 0.083
cellular divalent inorganic cation homeostasis GO:0072503 128 0.081
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.080
glycoprotein metabolic process GO:0009100 110 0.080
regulation of protein kinase b signaling GO:0051896 61 0.079
positive regulation of cyclase activity GO:0031281 13 0.077
regulation of insulin secretion GO:0050796 33 0.077
cytosolic calcium ion transport GO:0060401 48 0.077
regulation of cell development GO:0060284 161 0.077
positive regulation of developmental process GO:0051094 314 0.076
regulation of cation channel activity GO:2001257 33 0.076
regulation of cytokinesis GO:0032465 45 0.076
purine ribonucleoside catabolic process GO:0046130 398 0.076
cell projection morphogenesis GO:0048858 129 0.076
Rat
regulation of transporter activity GO:0032409 82 0.076
cell projection organization GO:0030030 252 0.075
Rat
regulation of ion transmembrane transporter activity GO:0032412 72 0.074
regulation of growth hormone secretion GO:0060123 3 0.074
fatty acid derivative transport GO:1901571 11 0.073
regulation of protein localization GO:0032880 296 0.070
Rat
negative regulation of lipid metabolic process GO:0045833 38 0.070
g protein coupled receptor internalization GO:0002031 6 0.070
response to radiation GO:0009314 151 0.069
monocarboxylic acid transport GO:0015718 32 0.068
renal system process GO:0003014 25 0.067
Rat
negative regulation of camp metabolic process GO:0030815 9 0.065
response to organonitrogen compound GO:0010243 156 0.065
Mouse Rat
negative regulation of cyclic nucleotide metabolic process GO:0030800 10 0.065
long chain fatty acid transport GO:0015909 18 0.064
positive regulation of cell cycle GO:0045787 140 0.064
hydrogen transport GO:0006818 23 0.063
peptide hormone secretion GO:0030072 50 0.062
cognition GO:0050890 43 0.062
determination of adult lifespan GO:0008340 2 0.062
negative regulation of cation channel activity GO:2001258 12 0.061
neurotransmitter transport GO:0006836 10 0.061
Rat
amino acid transport GO:0006865 28 0.061
Rat
regulation of cell division GO:0051302 116 0.060
monovalent inorganic cation homeostasis GO:0055067 37 0.060
Rat
secretion GO:0046903 254 0.060
Rat
purine containing compound catabolic process GO:0072523 411 0.060
negative regulation of intracellular signal transduction GO:1902532 183 0.059
positive regulation of cell development GO:0010720 92 0.059
negative regulation of transmembrane transport GO:0034763 29 0.059
regulation of transmembrane transport GO:0034762 139 0.058
negative regulation of striated muscle contraction GO:0045988 2 0.058
cellular amine metabolic process GO:0044106 41 0.058
maintenance of location GO:0051235 112 0.058
positive regulation of lyase activity GO:0051349 16 0.057
negative regulation of locomotion GO:0040013 118 0.057
Rat
positive regulation of hormone secretion GO:0046887 25 0.057
regulation of transferase activity GO:0051338 355 0.057
Rat
positive regulation of cell differentiation GO:0045597 211 0.057
release of sequestered calcium ion into cytosol GO:0051209 41 0.057
positive regulation of cellular amine metabolic process GO:0033240 7 0.056
behavioral response to cocaine GO:0048148 1 0.056
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.055
positive regulation of blood pressure GO:0045777 3 0.054
nucleoside catabolic process GO:0009164 408 0.054
negative regulation of calcium ion transport GO:0051926 19 0.054
cytosolic calcium ion homeostasis GO:0051480 89 0.053
vascular process in circulatory system GO:0003018 29 0.053
Rat
cellular homeostasis GO:0019725 196 0.053
receptor metabolic process GO:0043112 81 0.052
negative regulation of immune system process GO:0002683 136 0.052
Mouse
glycosyl compound catabolic process GO:1901658 413 0.051
glycoprotein biosynthetic process GO:0009101 91 0.051
negative regulation of response to external stimulus GO:0032102 83 0.051
Mouse Rat
defense response GO:0006952 315 0.050
Mouse
growth GO:0040007 202 0.050
negative regulation of muscle contraction GO:0045932 3 0.049
sensory perception of temperature stimulus GO:0050951 1 0.049
negative regulation of transporter activity GO:0032410 25 0.049
cellular chemical homeostasis GO:0055082 180 0.049
regulation of growth GO:0040008 165 0.049
negative regulation of insulin secretion GO:0046676 9 0.049
positive regulation of neurogenesis GO:0050769 49 0.049
response to drug GO:0042493 81 0.048
Rat
peptidyl tyrosine phosphorylation GO:0018108 170 0.048
positive regulation of endocytosis GO:0045807 42 0.048
cytoplasmic transport GO:0016482 379 0.048
behavior GO:0007610 112 0.048
Mouse Rat
detection of stimulus involved in sensory perception GO:0050906 43 0.048
divalent inorganic cation homeostasis GO:0072507 136 0.047
negative regulation of nucleotide biosynthetic process GO:0030809 11 0.047
neuromuscular process GO:0050905 15 0.047
Rat
pigmentation GO:0043473 22 0.046
negative regulation of nucleotide metabolic process GO:0045980 29 0.046
negative regulation of leukocyte migration GO:0002686 14 0.045
female gamete generation GO:0007292 2 0.045
regulation of response to wounding GO:1903034 101 0.045
Mouse
metal ion transport GO:0030001 272 0.045
Rat
negative adaptation of signaling pathway GO:0022401 7 0.045
guanosine containing compound catabolic process GO:1901069 239 0.045
ribonucleoside catabolic process GO:0042454 406 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.045
response to light stimulus GO:0009416 87 0.043
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 5 0.043
regulation of anion transport GO:0044070 25 0.043
Rat
cell development GO:0048468 328 0.043
Rat
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.043
regulation of cell differentiation GO:0045595 393 0.043
cellular amino acid metabolic process GO:0006520 116 0.043
cell part morphogenesis GO:0032990 137 0.042
Rat
regulation of endocytosis GO:0030100 72 0.042
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 5 0.042
cation transmembrane transport GO:0098655 238 0.042
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 2 0.042
response to inorganic substance GO:0010035 127 0.041
leukocyte migration GO:0050900 107 0.041
guanosine containing compound metabolic process GO:1901068 244 0.041
regulation of lipid metabolic process GO:0019216 96 0.041
response to mechanical stimulus GO:0009612 51 0.041
regulation of cardiac muscle contraction GO:0055117 33 0.040
cellular metal ion homeostasis GO:0006875 146 0.040
regulation of muscle system process GO:0090257 53 0.039
ribonucleotide catabolic process GO:0009261 405 0.039
morphogenesis of a branching structure GO:0001763 21 0.039
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 10 0.039
gtp metabolic process GO:0046039 239 0.038
response to toxic substance GO:0009636 37 0.038
negative regulation of calcium ion transmembrane transport GO:1903170 11 0.038
response to transition metal nanoparticle GO:1990267 29 0.037
neurogenesis GO:0022008 169 0.037
Rat
membrane organization GO:0061024 292 0.037
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
positive regulation of growth hormone secretion GO:0060124 2 0.036
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 7 0.035
cardiac muscle contraction GO:0060048 34 0.035
acute inflammatory response GO:0002526 21 0.035
regulation of kinase activity GO:0043549 314 0.035
Rat
negative regulation of response to wounding GO:1903035 47 0.035
Mouse
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.035
regulation of gtpase activity GO:0043087 180 0.034
regulation of ion transmembrane transport GO:0034765 132 0.034
proline transport GO:0015824 4 0.033
regulation of sodium proton antiporter activity GO:0032415 3 0.033
immune response GO:0006955 307 0.033
positive regulation of peptide hormone secretion GO:0090277 15 0.033
positive regulation of immune system process GO:0002684 283 0.033
nervous system development GO:0007399 293 0.033
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.032
regulation of postsynaptic membrane potential GO:0060078 1 0.032
Mouse Rat
respiratory gaseous exchange GO:0007585 3 0.032
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.032
negative regulation of apoptotic process GO:0043066 316 0.032
Rat
nucleoside triphosphate metabolic process GO:0009141 422 0.032
amine metabolic process GO:0009308 44 0.032
multicellular organismal aging GO:0010259 3 0.032
negative regulation of protein kinase b signaling GO:0051898 17 0.032
regulation of stem cell proliferation GO:0072091 15 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.031
regulation of leukocyte activation GO:0002694 115 0.031
Mouse
regulation of acute inflammatory response GO:0002673 13 0.030
inorganic cation transmembrane transport GO:0098662 194 0.030
negative regulation of camp biosynthetic process GO:0030818 9 0.030
striatum development GO:0021756 2 0.029
positive regulation of sodium ion transport GO:0010765 14 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
nucleotide catabolic process GO:0009166 408 0.029
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.029
positive regulation of gtpase activity GO:0043547 166 0.029
regulation of glycoprotein metabolic process GO:1903018 19 0.028
regulation of immune response GO:0050776 201 0.028
response to wounding GO:0009611 168 0.028
Mouse
cell projection assembly GO:0030031 126 0.028
positive regulation of growth GO:0045927 58 0.028
post embryonic development GO:0009791 2 0.028

ADORA2A disease predictions

Disease DO term ID Size Probability Func Analog Org
substance related disorder DOID:303 10 0.099
disease of mental health DOID:150 70 0.099