IMP

Process View

Homo sapiens

14 genes annotated in human

Multi-species View

sodium ion homeostasis

GO:0055078

Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sodium ion homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "sodium ion homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
ADORA2A	adenosine A2a receptor	0.999	Rat
DRD2	dopamine receptor D2	0.996	Mouse
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.985
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.931
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.828
TBC1D10A	TBC1 domain family, member 10A	0.796
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.786
NCOA1	nuclear receptor coactivator 1	0.762
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.722
EZR	ezrin	0.521
NAMPT	nicotinamide phosphoribosyltransferase	0.480
PTEN	phosphatase and tensin homolog	0.439
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.385
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.286
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.235
ADORA1	adenosine A1 receptor	0.228	Rat
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.190
NECAB2	N-terminal EF-hand calcium binding protein 2	0.185
GLP1R	glucagon-like peptide 1 receptor	0.166
TMF1	TATA element modulatory factor 1	0.083
CREBBP	CREB binding protein	0.079
ADRB2	adrenergic, beta-2-, receptor, surface	0.057
NDRG2	NDRG family member 2	0.050
NCOA2	nuclear receptor coactivator 2	0.050
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.049
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.047
EPN1	epsin 1	0.047
ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	0.046
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.045
ARRDC3	arrestin domain containing 3	0.044
PDZK1	PDZ domain containing 1	0.043
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.041	Human
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.041
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.036
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.034
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.030
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.026
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.023
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.023
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.022	Human
CNR1	cannabinoid receptor 1 (brain)	0.022
QKI	quaking homolog, KH domain RNA binding (mouse)	0.021
NF2	neurofibromin 2 (merlin)	0.020
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.018
PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2	0.017
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.017
RICTOR	RPTOR independent companion of MTOR, complex 2	0.017
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.015
AP1M2	adaptor-related protein complex 1, mu 2 subunit	0.015
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.015
PIGR	polymeric immunoglobulin receptor	0.015
FGFR1	fibroblast growth factor receptor 1	0.015
MUC4	mucin 4, cell surface associated	0.015
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.014
WFDC2	WAP four-disulfide core domain 2	0.014
TACR1	tachykinin receptor 1	0.014	Rat
NPY	neuropeptide Y	0.014
PRSS8	protease, serine, 8	0.013
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.013
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.013
CREB1	cAMP responsive element binding protein 1	0.013
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.012
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.012
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.012
TMEM30B	transmembrane protein 30B	0.012
SPDEF	SAM pointed domain containing ets transcription factor	0.012
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.012
KAT2B	K(lysine) acetyltransferase 2B	0.012
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.012
CRIP2	cysteine-rich protein 2	0.011
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.011
CLCN3	chloride channel 3	0.011
PCDH1	protocadherin 1	0.011
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.011
LGALS4	lectin, galactoside-binding, soluble, 4	0.011
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.011
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.011
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.011
VIL1	villin 1	0.010
TAC1	tachykinin, precursor 1	0.010	Rat
AVP	arginine vasopressin	0.010
PTPRN	protein tyrosine phosphatase, receptor type, N	0.010