IMP
Process View
negative adaptation of signaling pathway
The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative adaptation of signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.498 | ||
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.285 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.132 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.115 | ||
| MPDZ | multiple PDZ domain protein | 0.112 | ||
| MAPK10 | mitogen-activated protein kinase 10 | 0.092 | ||
| ZNF496 | zinc finger protein 496 | 0.086 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.050 | ||
| GNMT | glycine N-methyltransferase | 0.048 | ||
| HDAC6 | histone deacetylase 6 | 0.045 | ||
| ADORA2A | adenosine A2a receptor | 0.045 | ||
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.036 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.036 | ||
| YY1 | YY1 transcription factor | 0.035 | ||
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.024 | ||
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 0.021 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.017 | ||
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.015 | ||
| LIMK1 | LIM domain kinase 1 | 0.013 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.011 | ||
| CDK7 | cyclin-dependent kinase 7 | 0.011 | ||
| DGKZ | diacylglycerol kinase, zeta | 0.010 |