|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.992
|
|
|
monocyte activation
|
GO:0042117 |
3 |
0.990
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.983
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.949
|
Mouse |
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.947
|
Fly |
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.931
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.915
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.912
|
Fly |
|
amine metabolic process
|
GO:0009308 |
44 |
0.887
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.856
|
Mouse |
|
regulation of cardiac muscle hypertrophy in response to stress
|
GO:1903242 |
2 |
0.853
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.850
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.840
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.840
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.813
|
Mouse |
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.790
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.787
|
Mouse |
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.784
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.758
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.746
|
|
|
secretion
|
GO:0046903 |
254 |
0.744
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.744
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.735
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.726
|
Mouse |
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.724
|
Mouse |
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.722
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.720
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.710
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.666
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.662
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.658
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.652
|
Mouse |
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.646
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.627
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.627
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.619
|
Mouse |
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.611
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.607
|
Mouse Fly |
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.589
|
Fly |
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.588
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.584
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.570
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.565
|
|
|
t cell chemotaxis
|
GO:0010818 |
10 |
0.528
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.525
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.522
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.510
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.508
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.506
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.504
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.495
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.491
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.482
|
Mouse |
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.477
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.471
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.469
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.469
|
Fly |
|
generation of neurons
|
GO:0048699 |
152 |
0.469
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.453
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.446
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.443
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.436
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.434
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.429
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.424
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.416
|
|
|
behavior
|
GO:0007610 |
112 |
0.412
|
Fly |
|
cytokine production
|
GO:0001816 |
247 |
0.409
|
Mouse |
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.408
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.395
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.393
|
Mouse |
|
response to wounding
|
GO:0009611 |
168 |
0.390
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.386
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.385
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.379
|
Mouse Fly |
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.374
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.369
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.369
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.363
|
|
|
cell activation
|
GO:0001775 |
213 |
0.361
|
Mouse |
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.358
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.358
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.358
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.355
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.353
|
|
|
mating
|
GO:0007618 |
1 |
0.348
|
Fly |
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.347
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.343
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.343
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.337
|
Worm |
|
interleukin 8 production
|
GO:0032637 |
51 |
0.336
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.330
|
Fly |
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.326
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.320
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.319
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.319
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.316
|
Fly |
|
macrophage fusion
|
GO:0034238 |
1 |
0.314
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.313
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.313
|
|
|
growth
|
GO:0040007 |
202 |
0.309
|
Fly |
|
transmembrane transport
|
GO:0055085 |
399 |
0.304
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.300
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.299
|
Fly |
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.292
|
Mouse Fly |
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.289
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.289
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.286
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.272
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.271
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.271
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.267
|
Mouse Fly |
|
epidermis development
|
GO:0008544 |
59 |
0.266
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.263
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.258
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.254
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.250
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.248
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.245
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.243
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.241
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.240
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.240
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.233
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.231
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.231
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.229
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.227
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.225
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.223
|
|
|
skin development
|
GO:0043588 |
76 |
0.220
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.218
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.217
|
Mouse |
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.215
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.215
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.215
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.214
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.214
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.214
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.213
|
|
|
keratinocyte migration
|
GO:0051546 |
6 |
0.213
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.209
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.208
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.207
|
Mouse |
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.207
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.207
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.206
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.205
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.203
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.200
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.199
|
|
|
cellular response to epinephrine stimulus
|
GO:0071872 |
2 |
0.198
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.197
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.196
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.195
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.193
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.193
|
Mouse |
|
response to light stimulus
|
GO:0009416 |
87 |
0.190
|
Fly |
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.187
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.186
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.186
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.185
|
Mouse |
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.182
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.182
|
|
|
system process
|
GO:0003008 |
349 |
0.181
|
Mouse |
|
muscle system process
|
GO:0003012 |
81 |
0.179
|
Mouse |
|
response to uv
|
GO:0009411 |
73 |
0.177
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.176
|
|
|
pma inducible membrane protein ectodomain proteolysis
|
GO:0051088 |
3 |
0.175
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.175
|
Fly |
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.174
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.172
|
Mouse |
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.172
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.171
|
|
|
positive regulation of cell adhesion mediated by integrin
|
GO:0033630 |
9 |
0.170
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.170
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.169
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.167
|
Fly |
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.167
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.166
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.165
|
|
|
immune system development
|
GO:0002520 |
195 |
0.165
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.165
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.163
|
|
|
defense response
|
GO:0006952 |
315 |
0.162
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.161
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.161
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.160
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.159
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.157
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.156
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.155
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.155
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.155
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.155
|
|
|
arginine metabolic process
|
GO:0006525 |
3 |
0.154
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.153
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.153
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.152
|
Mouse |
|
response to oxidative stress
|
GO:0006979 |
121 |
0.152
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.151
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.150
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.149
|
|
|
cell growth
|
GO:0016049 |
160 |
0.148
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.147
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.147
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.147
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.145
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.142
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.142
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.141
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.140
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.139
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.137
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.136
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.134
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.133
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.133
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.132
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.131
|
Fly |
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.131
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.130
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.129
|
|
|
wound healing
|
GO:0042060 |
115 |
0.127
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.126
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.126
|
Fly |
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.125
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.124
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.121
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.118
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.118
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.118
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.117
|
|
|
neuron development
|
GO:0048666 |
113 |
0.115
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.114
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.114
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.113
|
|
|
negative regulation of nitric oxide mediated signal transduction
|
GO:0010751 |
2 |
0.112
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.112
|
|
|
positive regulation of epidermal growth factor receptor signaling pathway
|
GO:0045742 |
11 |
0.111
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.110
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.107
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.107
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.107
|
Fly |
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.106
|
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.105
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.105
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.105
|
|
|
segmentation
|
GO:0035282 |
4 |
0.105
|
Fly |
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.104
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.104
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.104
|
Human |
|
protein import
|
GO:0017038 |
130 |
0.104
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.103
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.102
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.101
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.100
|
Mouse |
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.100
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.100
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.099
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.098
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.098
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.098
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.096
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.096
|
Fly |
|
protein secretion
|
GO:0009306 |
98 |
0.096
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.096
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.096
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.095
|
Human |
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.094
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.094
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.094
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.094
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.093
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.093
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.092
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.091
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.090
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
2 |
0.090
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.090
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.088
|
Fly |
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.087
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.087
|
Fly |
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.087
|
|
|
spleen development
|
GO:0048536 |
1 |
0.086
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.086
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.085
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.085
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.084
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.084
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
8 |
0.084
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.084
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.084
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.083
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.083
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.082
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.082
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.082
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.082
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.081
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.081
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.080
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.080
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.080
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.080
|
|
|
immune response
|
GO:0006955 |
307 |
0.079
|
Mouse |
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.079
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.079
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.076
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.076
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.076
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.075
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.074
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.074
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.073
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.073
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.072
|
Human |
|
response to high density lipoprotein particle
|
GO:0055099 |
1 |
0.071
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.071
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.071
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.071
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.071
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.070
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.069
|
Fly |
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.069
|
Fly |
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.069
|
Mouse |
|
chemotaxis
|
GO:0006935 |
157 |
0.068
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.068
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.067
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.067
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.066
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.066
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.066
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.065
|
Mouse |
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.065
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.065
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.065
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.063
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.063
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.063
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.062
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.062
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.061
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.061
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.060
|
Fly |
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.060
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.060
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.060
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.060
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.060
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.059
|
|
|
cell development
|
GO:0048468 |
328 |
0.059
|
Fly |
|
regulation of ion transport
|
GO:0043269 |
189 |
0.059
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.058
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.058
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.057
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.056
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.056
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.056
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.056
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.056
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.055
|
|
|
tube development
|
GO:0035295 |
125 |
0.055
|
Mouse |
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.055
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.055
|
|
|
cation transport
|
GO:0006812 |
331 |
0.055
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.055
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.054
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.054
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.054
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.054
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.054
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.054
|
Fly |
|
actin filament based process
|
GO:0030029 |
224 |
0.053
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.053
|
Fly |
|
single organism cellular localization
|
GO:1902580 |
332 |
0.053
|
|
|
response to drug
|
GO:0042493 |
81 |
0.052
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.052
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.052
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.051
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.051
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.051
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.051
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.051
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.050
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.049
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.049
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.048
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.048
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.048
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.048
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.048
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.047
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.047
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.047
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.047
|
|
|
brain development
|
GO:0007420 |
97 |
0.047
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.046
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.046
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.046
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.046
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.046
|
|
|
positive regulation of macrophage fusion
|
GO:0034241 |
1 |
0.046
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.046
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.046
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.045
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.045
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.045
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.044
|
|
|
anion transport
|
GO:0006820 |
161 |
0.044
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.044
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.044
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.044
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.044
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.043
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.043
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.043
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.043
|
|
|
positive regulation of synaptic vesicle transport
|
GO:1902805 |
1 |
0.043
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.042
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.042
|
Mouse |
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.042
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.042
|
Mouse |
|
response to virus
|
GO:0009615 |
126 |
0.042
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
30 |
0.042
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.042
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.041
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.041
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.041
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.041
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.041
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.041
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.041
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.040
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.039
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.039
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.039
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.039
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
1 |
0.039
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.039
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.038
|
|
|
reproduction
|
GO:0000003 |
63 |
0.038
|
Worm Fly |
|
atp catabolic process
|
GO:0006200 |
157 |
0.037
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.037
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.036
|
Mouse |
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.036
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.035
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.035
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.035
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.035
|
Mouse |
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.035
|
Mouse |
|
cellular homeostasis
|
GO:0019725 |
196 |
0.035
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.035
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.035
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.035
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.035
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.034
|
Mouse Fly |
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.034
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.034
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.034
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.034
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.033
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.033
|
|
|
rna processing
|
GO:0006396 |
255 |
0.033
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.032
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.032
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.032
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.032
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.032
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.032
|
Fly |
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.031
|
Mouse |
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.031
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.031
|
|
|
cell division
|
GO:0051301 |
168 |
0.031
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.031
|
|
|
embryo development
|
GO:0009790 |
123 |
0.031
|
Mouse Worm Fly |
|
dna repair
|
GO:0006281 |
198 |
0.031
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.030
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.030
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.029
|
Fly |
|
atp metabolic process
|
GO:0046034 |
176 |
0.029
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.029
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.029
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.029
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.029
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.029
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.029
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.029
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.029
|
|
|
striated muscle adaptation
|
GO:0014888 |
4 |
0.028
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.028
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.028
|
Mouse |
|
negative regulation of growth
|
GO:0045926 |
97 |
0.028
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.028
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.027
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.027
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.027
|
|