|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.996
|
Mouse |
|
|
dna hypermethylation
|
GO:0044026 |
1 |
0.929
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.849
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.841
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.841
|
Rat |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.833
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.810
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.771
|
|
|
|
positive regulation of histone h3 k4 methylation
|
GO:0051571 |
8 |
0.769
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.753
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.725
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.697
|
Rat |
|
|
dna modification
|
GO:0006304 |
27 |
0.684
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.668
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.653
|
|
|
|
negative regulation of histone methylation
|
GO:0031061 |
6 |
0.623
|
|
|
|
regulation of histone h3 k27 methylation
|
GO:0061085 |
4 |
0.622
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.616
|
Rat |
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.595
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.558
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.533
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
3 |
0.526
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.520
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.516
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.489
|
|
|
|
dna methylation on cytosine
|
GO:0032776 |
3 |
0.476
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.470
|
Rat |
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.466
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.450
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.445
|
Rat |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.444
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.437
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.424
|
Mouse Rat |
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.421
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.416
|
|
|
|
negative regulation of epidermis development
|
GO:0045683 |
5 |
0.415
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.409
|
|
|
|
positive regulation of histone methylation
|
GO:0031062 |
12 |
0.408
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.408
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.406
|
|
|
|
regulation of gene expression by genetic imprinting
|
GO:0006349 |
1 |
0.386
|
Mouse |
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.380
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.361
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.361
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.352
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.346
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.333
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.325
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.321
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
2 |
0.318
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.311
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.302
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.287
|
Mouse Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.269
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.268
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.261
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.257
|
Mouse |
|
|
response to amino acid
|
GO:0043200 |
14 |
0.255
|
Mouse |
|
|
regulation of histone methylation
|
GO:0031060 |
16 |
0.249
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.249
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.245
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.244
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.242
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.241
|
Rat |
|
|
response to hormone
|
GO:0009725 |
175 |
0.230
|
Rat |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.224
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.222
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.218
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.218
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.217
|
Rat |
|
|
dna methylation or demethylation
|
GO:0044728 |
19 |
0.210
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.210
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.206
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.205
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.202
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.202
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.192
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.190
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.180
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.180
|
Rat |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.179
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.178
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.178
|
Rat |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.177
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.177
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.177
|
Rat |
|
|
response to drug
|
GO:0042493 |
81 |
0.176
|
Rat |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.169
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.166
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.162
|
Rat |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.161
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.159
|
Mouse Rat |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.157
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.155
|
|
|
|
tricarboxylic acid cycle
|
GO:0006099 |
4 |
0.146
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.143
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.142
|
|
|
|
negative regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034244 |
4 |
0.140
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.140
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.138
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.134
|
Rat |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.133
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.133
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.133
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.130
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.126
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.126
|
|
|
|
response to testosterone
|
GO:0033574 |
1 |
0.123
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.123
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
4 |
0.121
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.121
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.119
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.115
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.112
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.112
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.111
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.110
|
|
|
|
histone h3 k27 methylation
|
GO:0070734 |
6 |
0.110
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.108
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.105
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.105
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.104
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.101
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.101
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.100
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.100
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.099
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.098
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.098
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.097
|
|
|
|
maintenance of dna methylation
|
GO:0010216 |
3 |
0.097
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.097
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.097
|
Mouse |
|
|
sodium ion export from cell
|
GO:0036376 |
6 |
0.096
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.096
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.096
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.095
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.094
|
Mouse |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.094
|
|
|
|
response to vitamin
|
GO:0033273 |
13 |
0.094
|
Rat |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.093
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.093
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.092
|
Mouse Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.092
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.091
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.091
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.091
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.091
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.090
|
Rat |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.090
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.090
|
Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.089
|
Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.088
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.088
|
Rat |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.087
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.085
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.084
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.084
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.084
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.083
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.080
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.080
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.077
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.076
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.076
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.076
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.075
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.075
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.075
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.075
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.072
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.072
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.072
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.070
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.069
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.069
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.069
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.069
|
Rat |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.068
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.068
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.067
|
|
|
|
cuticle development
|
GO:0042335 |
1 |
0.067
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.066
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.065
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.065
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.064
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.064
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.063
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.063
|
Rat |
|
|
cerebellum development
|
GO:0021549 |
2 |
0.062
|
|
|
|
g1 to g0 transition
|
GO:0070314 |
2 |
0.061
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.060
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.060
|
|
|
|
histone h3 k9 methylation
|
GO:0051567 |
10 |
0.060
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.060
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.059
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.058
|
Rat |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.057
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.056
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.056
|
|
|
|
growth
|
GO:0040007 |
202 |
0.056
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.056
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.056
|
Rat |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.055
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.055
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.055
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.055
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.054
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.054
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.054
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.053
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.053
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.053
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.053
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.052
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.052
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.052
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.051
|
|
|
|
response to lead ion
|
GO:0010288 |
1 |
0.051
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.051
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.051
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.050
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.050
|
|
|
|
head development
|
GO:0060322 |
108 |
0.050
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.049
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.049
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.048
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.048
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.048
|
Rat |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.048
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.047
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.047
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.047
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.047
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.047
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.046
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.046
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.046
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.046
|
|
|
|
regulation of histone h3 k9 methylation
|
GO:0051570 |
6 |
0.046
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.046
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.046
|
Rat |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.046
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.045
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.045
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.045
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.045
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.045
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.044
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.044
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.044
|
Rat |
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.044
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.043
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.043
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.043
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.043
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.043
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.042
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.042
|
Rat |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.042
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.042
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.041
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.041
|
Rat |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.041
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.040
|
|
|
|
negative regulation of retinoic acid receptor signaling pathway
|
GO:0048387 |
4 |
0.040
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.040
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.039
|
Rat |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.039
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.039
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.039
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.038
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.038
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.038
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.038
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.037
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.037
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.037
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.037
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.036
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.036
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.036
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.036
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.036
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.036
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.036
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
11 |
0.036
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.036
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.035
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.035
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.035
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.035
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.034
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.034
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.034
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.033
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.033
|
|
|
|
aging
|
GO:0007568 |
66 |
0.033
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.032
|
Mouse |
|
|
cellular response to alcohol
|
GO:0097306 |
29 |
0.032
|
Rat |
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.032
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.032
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.032
|
Rat |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.032
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.032
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.032
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.032
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.031
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.031
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.031
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.031
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.031
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.030
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.030
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.030
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.030
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.030
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.030
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.030
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.029
|
Rat |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.029
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.029
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.029
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.029
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.029
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.029
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.029
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.029
|
Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.028
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.028
|
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
2 |
0.028
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.028
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.028
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.028
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.028
|
Rat |
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.028
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.027
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.027
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.027
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.027
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.027
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.027
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.027
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.026
|
Mouse Rat |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.026
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.026
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.026
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.026
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
13 |
0.026
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.026
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.026
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.026
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.026
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.026
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.026
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.026
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.025
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.025
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.025
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.025
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.025
|
|
|
|
potassium ion import
|
GO:0010107 |
9 |
0.025
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.025
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.024
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.024
|
Rat |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.024
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.024
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.024
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.024
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.024
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.024
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.024
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.024
|
|
|
|
regulation of histone h3 k4 methylation
|
GO:0051569 |
10 |
0.024
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.024
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.024
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.024
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.024
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.023
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.023
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.023
|
Rat |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.023
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.023
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.023
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.023
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.023
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.023
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.023
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.022
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.022
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.022
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.022
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
12 |
0.022
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.022
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.022
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.022
|
|
|
|
regulation of atp catabolic process
|
GO:1903289 |
25 |
0.022
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.022
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.022
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.022
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.022
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.022
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.022
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.022
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.022
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.022
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.022
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.022
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.021
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.021
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.021
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.021
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.021
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.021
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.021
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.021
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.021
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.021
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.021
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.021
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.021
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.021
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.021
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.021
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.020
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.020
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.020
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.020
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.020
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.020
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.020
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.020
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.020
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.020
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.020
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.020
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.020
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.020
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.020
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.020
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.020
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.020
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.020
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.020
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.019
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.019
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.019
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.019
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.019
|
|
|
|
negative regulation of intracellular transport of viral material
|
GO:1901253 |
2 |
0.019
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.019
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.019
|
|
|
|
attachment of mitotic spindle microtubules to kinetochore
|
GO:0051315 |
3 |
0.019
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.019
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.019
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.019
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.019
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.019
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.019
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.019
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.019
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.019
|
|
|
|
regulation of toll signaling pathway
|
GO:0008592 |
1 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.018
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.018
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.018
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
2 |
0.018
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.018
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.018
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.018
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.018
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.018
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.018
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.018
|
|
|
|
sodium ion export
|
GO:0071436 |
7 |
0.018
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
1 |
0.018
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|