Homo sapiens

140 known processes

DNMT3B

DNA (cytosine-5-)-methyltransferase 3 beta

(Aliases: M.HsaIIIB,ICF)

DNMT3B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
methylation dependent chromatin silencing GO:0006346 3 0.996
Mouse
dna hypermethylation GO:0044026 1 0.929
histone lysine methylation GO:0034968 50 0.849
histone h3 k4 methylation GO:0051568 27 0.841
response to caffeine GO:0031000 3 0.841
Rat
protein modification by small protein conjugation GO:0032446 342 0.833
genetic imprinting GO:0071514 1 0.810
Mouse
chromatin organization GO:0006325 351 0.771
positive regulation of histone h3 k4 methylation GO:0051571 8 0.769
histone modification GO:0016570 251 0.753
purine ribonucleoside metabolic process GO:0046128 437 0.725
Rat
cellular amino acid metabolic process GO:0006520 116 0.697
Rat
dna modification GO:0006304 27 0.684
cofactor metabolic process GO:0051186 87 0.668
histone h3 k9 modification GO:0061647 11 0.653
negative regulation of histone methylation GO:0031061 6 0.623
regulation of histone h3 k27 methylation GO:0061085 4 0.622
alpha amino acid metabolic process GO:1901605 72 0.616
Rat
positive regulation of chromatin modification GO:1903310 30 0.595
histone monoubiquitination GO:0010390 20 0.558
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.533
negative regulation of histone h3 k9 methylation GO:0051573 3 0.526
retina layer formation GO:0010842 3 0.520
positive regulation of chromosome organization GO:2001252 41 0.516
covalent chromatin modification GO:0016569 254 0.489
dna methylation on cytosine GO:0032776 3 0.476
sulfur compound metabolic process GO:0006790 101 0.470
Rat
negative regulation of epidermal cell differentiation GO:0045605 4 0.466
positive regulation of cellular component organization GO:0051130 376 0.450
response to lipid GO:0033993 206 0.445
Rat
protein ubiquitination GO:0016567 314 0.444
negative regulation of cellular component organization GO:0051129 235 0.437
response to nitrogen compound GO:1901698 184 0.424
Mouse Rat
histone ubiquitination GO:0016574 31 0.421
macromolecule methylation GO:0043414 97 0.416
negative regulation of epidermis development GO:0045683 5 0.415
chromatin modification GO:0016568 298 0.409
positive regulation of histone methylation GO:0031062 12 0.408
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.408
positive regulation of organelle organization GO:0010638 195 0.406
regulation of gene expression by genetic imprinting GO:0006349 1 0.386
Mouse
negative regulation of chromatin modification GO:1903309 21 0.380
protein alkylation GO:0008213 74 0.361
histone methylation GO:0016571 60 0.361
determination of adult lifespan GO:0008340 2 0.352
response to inorganic substance GO:0010035 127 0.346
response to metal ion GO:0010038 84 0.333
cellular macromolecule catabolic process GO:0044265 380 0.325
negative regulation of cellular protein metabolic process GO:0032269 353 0.321
regulation of dna methylation GO:0044030 2 0.318
modification dependent macromolecule catabolic process GO:0043632 212 0.311
coenzyme metabolic process GO:0006732 65 0.302
response to oxygen containing compound GO:1901700 369 0.287
Mouse Rat
positive regulation of protein phosphorylation GO:0001934 313 0.269
rostrocaudal neural tube patterning GO:0021903 1 0.268
dna conformation change GO:0071103 113 0.261
response to acid chemical GO:0001101 66 0.257
Mouse
response to amino acid GO:0043200 14 0.255
Mouse
regulation of histone methylation GO:0031060 16 0.249
purine nucleoside triphosphate metabolic process GO:0009144 412 0.249
positive regulation of phosphorylation GO:0042327 394 0.245
citrate metabolic process GO:0006101 2 0.244
nucleoside catabolic process GO:0009164 408 0.242
response to organic cyclic compound GO:0014070 204 0.241
Rat
response to hormone GO:0009725 175 0.230
Rat
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.224
negative regulation of protein metabolic process GO:0051248 391 0.222
response to radiation GO:0009314 151 0.218
Rat
regulation of transferase activity GO:0051338 355 0.218
response to abiotic stimulus GO:0009628 336 0.217
Rat
dna methylation or demethylation GO:0044728 19 0.210
nucleotide catabolic process GO:0009166 408 0.210
multicellular organismal aging GO:0010259 3 0.206
methylation GO:0032259 106 0.205
cellular protein catabolic process GO:0044257 261 0.202
negative regulation of protein modification process GO:0031400 200 0.202
glycosyl compound catabolic process GO:1901658 413 0.192
positive regulation of cell death GO:0010942 263 0.190
ubiquitin dependent protein catabolic process GO:0006511 206 0.180
response to steroid hormone GO:0048545 80 0.180
Rat
negative regulation of multicellular organismal process GO:0051241 317 0.179
regulation of mapk cascade GO:0043408 262 0.178
response to hypoxia GO:0001666 96 0.178
Rat
single organism cellular localization GO:1902580 332 0.177
positive regulation of protein kinase activity GO:0045860 190 0.177
response to extracellular stimulus GO:0009991 85 0.177
Rat
response to drug GO:0042493 81 0.176
Rat
mitotic cell cycle phase transition GO:0044772 162 0.169
ribonucleoside triphosphate catabolic process GO:0009203 391 0.166
response to decreased oxygen levels GO:0036293 96 0.162
Rat
cellular response to decreased oxygen levels GO:0036294 51 0.161
cellular response to oxygen containing compound GO:1901701 276 0.159
Mouse Rat
modification dependent protein catabolic process GO:0019941 209 0.157
regulation of cell cycle arrest GO:0071156 36 0.155
tricarboxylic acid cycle GO:0006099 4 0.146
response to other organism GO:0051707 261 0.143
regulation of purine nucleotide catabolic process GO:0033121 205 0.142
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.140
regulation of cell cycle GO:0051726 393 0.140
guanosine containing compound metabolic process GO:1901068 244 0.138
response to activity GO:0014823 0 0.134
Rat
negative regulation of chromosome organization GO:2001251 48 0.133
positive regulation of histone modification GO:0031058 29 0.133
regulation of cellular amine metabolic process GO:0033238 11 0.133
response to lipopolysaccharide GO:0032496 70 0.130
regulation of chromatin modification GO:1903308 51 0.126
regulation of cell cycle process GO:0010564 266 0.126
response to testosterone GO:0033574 1 0.123
regulation of gtpase activity GO:0043087 180 0.123
tricarboxylic acid metabolic process GO:0072350 4 0.121
positive regulation of transferase activity GO:0051347 227 0.121
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.119
ribonucleoside catabolic process GO:0042454 406 0.115
protein autoubiquitination GO:0051865 37 0.112
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.112
negative regulation of muscle cell differentiation GO:0051148 17 0.111
intracellular receptor signaling pathway GO:0030522 104 0.110
histone h3 k27 methylation GO:0070734 6 0.110
nucleoside phosphate catabolic process GO:1901292 412 0.108
gtp catabolic process GO:0006184 237 0.105
gene silencing GO:0016458 49 0.105
Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.104
regulation of nucleoside metabolic process GO:0009118 209 0.101
response to cocaine GO:0042220 1 0.101
Rat
regulation of cellular amino acid metabolic process GO:0006521 6 0.100
tissue morphogenesis GO:0048729 96 0.100
regulation of nucleotide metabolic process GO:0006140 269 0.099
amine metabolic process GO:0009308 44 0.098
dna packaging GO:0006323 77 0.098
nucleoside triphosphate metabolic process GO:0009141 422 0.097
maintenance of dna methylation GO:0010216 3 0.097
positive regulation of nucleotide metabolic process GO:0045981 230 0.097
cellular response to organonitrogen compound GO:0071417 124 0.097
Mouse
sodium ion export from cell GO:0036376 6 0.096
regulation of chromatin organization GO:1902275 56 0.096
response to growth factor GO:0070848 205 0.096
regulation of anatomical structure morphogenesis GO:0022603 286 0.095
cellular response to acid chemical GO:0071229 44 0.094
Mouse
metencephalon development GO:0022037 2 0.094
response to vitamin GO:0033273 13 0.094
Rat
positive regulation of catabolic process GO:0009896 310 0.093
positive regulation of kinase activity GO:0033674 204 0.093
response to organonitrogen compound GO:0010243 156 0.092
Mouse Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.092
positive regulation of cell cycle arrest GO:0071158 23 0.091
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.091
regulation of chromosome organization GO:0033044 103 0.091
negative regulation of cell cycle GO:0045786 193 0.091
regulation of cell differentiation GO:0045595 393 0.090
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.090
response to purine containing compound GO:0014074 40 0.090
Rat
nervous system development GO:0007399 293 0.089
Rat
response to biotic stimulus GO:0009607 276 0.088
neurogenesis GO:0022008 169 0.088
Rat
positive regulation of nucleotide catabolic process GO:0030813 185 0.087
cell cycle arrest GO:0007050 71 0.085
regulation of purine nucleotide metabolic process GO:1900542 264 0.084
positive regulation of cellular amine metabolic process GO:0033240 7 0.084
positive regulation of mapk cascade GO:0043410 190 0.084
response to external biotic stimulus GO:0043207 261 0.083
ras protein signal transduction GO:0007265 73 0.080
nucleoside triphosphate catabolic process GO:0009143 394 0.080
negative regulation of histone modification GO:0031057 19 0.077
purine nucleoside catabolic process GO:0006152 398 0.076
response to molecule of bacterial origin GO:0002237 82 0.076
regulation of map kinase activity GO:0043405 108 0.076
eye morphogenesis GO:0048592 16 0.075
negative regulation of striated muscle cell differentiation GO:0051154 8 0.075
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.075
cellular response to reactive oxygen species GO:0034614 50 0.075
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.072
positive regulation of hydrolase activity GO:0051345 331 0.072
mitotic cell cycle GO:0000278 326 0.072
regulation of kinase activity GO:0043549 314 0.070
regulation of cellular component biogenesis GO:0044087 281 0.069
neural tube patterning GO:0021532 2 0.069
negative regulation of cell death GO:0060548 345 0.069
response to alkaloid GO:0043279 20 0.069
Rat
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.068
negative regulation of protein maturation GO:1903318 142 0.068
guanosine containing compound catabolic process GO:1901069 239 0.067
cuticle development GO:0042335 1 0.067
organophosphate catabolic process GO:0046434 430 0.066
negative regulation of cellular amine metabolic process GO:0033239 3 0.065
regulation of protein serine threonine kinase activity GO:0071900 179 0.065
hindbrain development GO:0030902 3 0.064
gland development GO:0048732 48 0.064
regulation of muscle cell differentiation GO:0051147 31 0.063
response to estradiol GO:0032355 23 0.063
Rat
cerebellum development GO:0021549 2 0.062
g1 to g0 transition GO:0070314 2 0.061
regulation of mitosis GO:0007088 63 0.060
regulation of cell growth GO:0001558 135 0.060
histone h3 k9 methylation GO:0051567 10 0.060
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
positive regulation of gtpase activity GO:0043547 166 0.059
positive regulation of developmental process GO:0051094 314 0.058
Rat
regulation of nucleotide catabolic process GO:0030811 205 0.057
transmembrane transport GO:0055085 399 0.056
purine ribonucleoside catabolic process GO:0046130 398 0.056
growth GO:0040007 202 0.056
post embryonic development GO:0009791 2 0.056
response to nutrient GO:0007584 20 0.056
Rat
protein localization to organelle GO:0033365 280 0.055
cellular response to inorganic substance GO:0071241 45 0.055
purine nucleotide catabolic process GO:0006195 405 0.055
ribonucleotide catabolic process GO:0009261 405 0.055
regulation of dna metabolic process GO:0051052 153 0.054
response to transforming growth factor beta GO:0071559 94 0.054
purine containing compound catabolic process GO:0072523 411 0.054
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.053
proteasomal protein catabolic process GO:0010498 176 0.053
cell type specific apoptotic process GO:0097285 125 0.053
protein targeting GO:0006605 187 0.053
regulation of protein maturation GO:1903317 150 0.052
epithelial cell differentiation GO:0030855 141 0.052
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.052
negative regulation of mitotic cell cycle GO:0045930 102 0.051
response to lead ion GO:0010288 1 0.051
intracellular protein transport GO:0006886 270 0.051
cell cycle phase transition GO:0044770 173 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.050
cellular ketone metabolic process GO:0042180 80 0.050
head development GO:0060322 108 0.050
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.049
positive regulation of cellular catabolic process GO:0031331 284 0.049
regulation of stem cell differentiation GO:2000736 56 0.048
positive regulation of cell growth GO:0030307 48 0.048
response to ionizing radiation GO:0010212 65 0.048
Rat
negative regulation of apoptotic signaling pathway GO:2001234 97 0.048
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.047
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.047
protein maturation GO:0051604 233 0.047
central nervous system development GO:0007417 123 0.047
epithelium development GO:0060429 227 0.047
mapk cascade GO:0000165 288 0.046
circadian rhythm GO:0007623 21 0.046
response to bacterium GO:0009617 144 0.046
regulation of intracellular protein transport GO:0033157 123 0.046
regulation of histone h3 k9 methylation GO:0051570 6 0.046
single organism membrane organization GO:0044802 268 0.046
neuron differentiation GO:0030182 138 0.046
Rat
meiotic chromosome segregation GO:0045132 4 0.046
nuclear transport GO:0051169 179 0.045
regulation of protein kinase activity GO:0045859 289 0.045
negative regulation of protein processing GO:0010955 142 0.045
protein monoubiquitination GO:0006513 39 0.045
cardiac muscle cell contraction GO:0086003 4 0.045
locomotory behavior GO:0007626 1 0.044
regulation of ion transport GO:0043269 189 0.044
protein catabolic process GO:0030163 325 0.044
cellular response to oxygen levels GO:0071453 55 0.044
Rat
cellular response to metal ion GO:0071248 43 0.044
response to ethanol GO:0045471 11 0.043
regulation of actin filament based process GO:0032970 141 0.043
nucleocytoplasmic transport GO:0006913 176 0.043
negative regulation of organelle organization GO:0010639 126 0.043
cytoplasmic transport GO:0016482 379 0.043
negative regulation of cell differentiation GO:0045596 171 0.042
response to alcohol GO:0097305 64 0.042
Rat
regulation of gtp catabolic process GO:0033124 180 0.042
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.042
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.041
response to toxic substance GO:0009636 37 0.041
Rat
positive regulation of map kinase activity GO:0043406 80 0.041
actin filament based process GO:0030029 224 0.040
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.040
cartilage development GO:0051216 31 0.040
response to nutrient levels GO:0031667 81 0.039
Rat
small gtpase mediated signal transduction GO:0007264 78 0.039
negative regulation of intracellular signal transduction GO:1902532 183 0.039
cellular response to growth factor stimulus GO:0071363 197 0.039
positive regulation of gtp catabolic process GO:0033126 166 0.038
posttranscriptional regulation of gene expression GO:0010608 213 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
regulation of striated muscle cell differentiation GO:0051153 25 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.037
tissue regeneration GO:0042246 3 0.037
pharynx development GO:0060465 1 0.037
regulation of proteolysis GO:0030162 293 0.037
cellular amine metabolic process GO:0044106 41 0.036
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
ion transmembrane transport GO:0034220 338 0.036
cellular response to hypoxia GO:0071456 51 0.036
maintenance of location in cell GO:0051651 62 0.036
protein targeting to nucleus GO:0044744 104 0.036
regulation of circadian rhythm GO:0042752 11 0.036
secretion GO:0046903 254 0.036
ectodermal placode formation GO:0060788 1 0.035
mitochondrion organization GO:0007005 156 0.035
chemotaxis GO:0006935 157 0.035
digestive system development GO:0055123 75 0.035
connective tissue development GO:0061448 39 0.034
negative regulation of programmed cell death GO:0043069 321 0.034
inorganic ion transmembrane transport GO:0098660 231 0.034
positive regulation of cell cycle GO:0045787 140 0.034
maintenance of location GO:0051235 112 0.033
regulation of cell division GO:0051302 116 0.033
aging GO:0007568 66 0.033
chromatin silencing GO:0006342 12 0.032
Mouse
cellular response to alcohol GO:0097306 29 0.032
Rat
cellular response to nerve growth factor stimulus GO:1990090 6 0.032
spindle elongation GO:0051231 4 0.032
response to estrogen GO:0043627 47 0.032
Rat
regulation of nuclear division GO:0051783 65 0.032
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.032
negative regulation of developmental process GO:0051093 247 0.032
i kappab kinase nf kappab signaling GO:0007249 166 0.032
mitotic nuclear division GO:0007067 119 0.031
cell projection organization GO:0030030 252 0.031
stem cell division GO:0017145 2 0.031
regulation of protein processing GO:0070613 150 0.031
cation transport GO:0006812 331 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.031
regulation of meiotic cell cycle GO:0051445 4 0.030
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
vesicle mediated transport GO:0016192 371 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.030
rna processing GO:0006396 255 0.030
embryonic camera type eye morphogenesis GO:0048596 2 0.030
negative regulation of transport GO:0051051 176 0.030
regulation of cell development GO:0060284 161 0.029
Rat
regulation of ras gtpase activity GO:0032318 128 0.029
regulation of growth GO:0040008 165 0.029
hippocampus development GO:0021766 1 0.029
positive regulation of ras gtpase activity GO:0032320 117 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
membrane organization GO:0061024 292 0.029
morphogenesis of embryonic epithelium GO:0016331 4 0.029
generation of neurons GO:0048699 152 0.029
Rat
intrinsic apoptotic signaling pathway GO:0097193 127 0.028
chromatin assembly GO:0031497 61 0.028
skeletal muscle tissue regeneration GO:0043403 2 0.028
inorganic cation transmembrane transport GO:0098662 194 0.028
cellular protein complex assembly GO:0043623 188 0.028
negative regulation of epithelial cell differentiation GO:0030857 6 0.028
regeneration GO:0031099 4 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
Rat
embryonic camera type eye development GO:0031076 2 0.028
neural crest cell development GO:0014032 3 0.027
protein methylation GO:0006479 74 0.027
female gamete generation GO:0007292 2 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
male meiosis GO:0007140 1 0.027
ion homeostasis GO:0050801 230 0.027
atp metabolic process GO:0046034 176 0.027
positive regulation of neural precursor cell proliferation GO:2000179 2 0.027
cellular response to endogenous stimulus GO:0071495 336 0.026
Mouse Rat
regulation of cellular component movement GO:0051270 334 0.026
secretion by cell GO:0032940 226 0.026
negative regulation of viral transcription GO:0032897 23 0.026
protein localization to nucleus GO:0034504 136 0.026
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.026
regulation of protein localization GO:0032880 296 0.026
regulation of protein transport GO:0051223 213 0.026
regulation of response to external stimulus GO:0032101 222 0.026
protein processing GO:0016485 226 0.026
regulation of cardiac muscle cell proliferation GO:0060043 4 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
single organism reproductive process GO:0044702 98 0.025
regulation of lipid biosynthetic process GO:0046890 47 0.025
cellular response to oxidative stress GO:0034599 85 0.025
cardiovascular system development GO:0072358 262 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
potassium ion import GO:0010107 9 0.025
neuron development GO:0048666 113 0.025
spinal cord development GO:0021510 4 0.024
response to oxygen levels GO:0070482 100 0.024
Rat
embryonic epithelial tube formation GO:0001838 4 0.024
oogenesis GO:0048477 2 0.024
regulation of cell morphogenesis GO:0022604 153 0.024
mitotic sister chromatid separation GO:0051306 18 0.024
rna splicing GO:0008380 131 0.024
pancreas development GO:0031016 19 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
regulation of histone h3 k4 methylation GO:0051569 10 0.024
response to reactive oxygen species GO:0000302 61 0.024
regulation of locomotion GO:0040012 329 0.024
positive regulation of cell cycle process GO:0090068 106 0.024
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.024
cellular response to cytokine stimulus GO:0071345 181 0.023
immune response GO:0006955 307 0.023
response to increased oxygen levels GO:0036296 4 0.023
Rat
actin polymerization or depolymerization GO:0008154 56 0.023
regulation of cell motility GO:2000145 299 0.023
embryonic digestive tract morphogenesis GO:0048557 2 0.023
striated muscle contraction GO:0006941 52 0.023
limbic system development GO:0021761 3 0.023
ectodermal placode development GO:0071696 1 0.023
epidermal cell differentiation GO:0009913 45 0.023
tube development GO:0035295 125 0.022
actin filament organization GO:0007015 128 0.022
segmentation GO:0035282 4 0.022
regulation of angiogenesis GO:0045765 92 0.022
regulation of epithelial to mesenchymal transition GO:0010717 37 0.022
cellular response to amino acid stimulus GO:0071230 12 0.022
Mouse
positive regulation of apoptotic process GO:0043065 246 0.022
endothelial cell migration GO:0043542 86 0.022
glycoprotein metabolic process GO:0009100 110 0.022
regulation of atp catabolic process GO:1903289 25 0.022
regulation of viral transcription GO:0046782 34 0.022
regulation of ion transmembrane transport GO:0034765 132 0.022
negative regulation of kinase activity GO:0033673 106 0.022
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.022
determination of dorsal ventral asymmetry GO:0048262 4 0.022
defense response to fungus GO:0050832 4 0.022
actin cytoskeleton organization GO:0030036 207 0.022
biological adhesion GO:0022610 331 0.022
chemokine c x c motif ligand 2 production GO:0072567 3 0.022
regulation of secretion GO:0051046 194 0.022
osteoblast differentiation GO:0001649 92 0.022
pituitary gland development GO:0021983 2 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.021
regulation of protein polymerization GO:0032271 63 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.021
negative regulation of axonogenesis GO:0050771 4 0.021
cardiac muscle contraction GO:0060048 34 0.021
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.021
negative regulation of cell division GO:0051782 31 0.021
response to virus GO:0009615 126 0.021
regulation of reactive oxygen species metabolic process GO:2000377 41 0.021
response to wounding GO:0009611 168 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
regulation of cell migration GO:0030334 289 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
oocyte differentiation GO:0009994 2 0.020
cellular chemical homeostasis GO:0055082 180 0.020
regulation of cardiac muscle tissue growth GO:0055021 4 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
blood vessel development GO:0001568 172 0.020
regulation of secretion by cell GO:1903530 177 0.020
extrinsic apoptotic signaling pathway GO:0097191 119 0.020
muscle cell differentiation GO:0042692 63 0.020
digestive tract development GO:0048565 75 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
associative learning GO:0008306 1 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.020
blastocyst development GO:0001824 3 0.020
adult locomotory behavior GO:0008344 1 0.020
actin mediated cell contraction GO:0070252 12 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
cell morphogenesis GO:0000902 296 0.020
apoptotic signaling pathway GO:0097190 268 0.020
regulation of glial cell differentiation GO:0045685 3 0.020
brain development GO:0007420 97 0.019
cellular lipid metabolic process GO:0044255 303 0.019
inner ear morphogenesis GO:0042472 4 0.019
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.019
response to tumor necrosis factor GO:0034612 76 0.019
negative regulation of intracellular transport of viral material GO:1901253 2 0.019
regulation of interleukin 2 secretion GO:1900040 2 0.019
viral gene expression GO:0019080 35 0.019
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.019
multi organism cellular process GO:0044764 156 0.019
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.019
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
response to cytokine GO:0034097 232 0.019
regulation of protein targeting GO:1903533 91 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
negative regulation of neural precursor cell proliferation GO:2000178 1 0.019
regulation of toll signaling pathway GO:0008592 1 0.019
regulation of binding GO:0051098 111 0.019
endosomal transport GO:0016197 129 0.018
mitotic cell cycle process GO:1903047 286 0.018
heart contraction GO:0060047 62 0.018
eyelid development in camera type eye GO:0061029 2 0.018
muscle system process GO:0003012 81 0.018
negative regulation of intracellular transport GO:0032387 60 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
response to fungus GO:0009620 4 0.018
embryonic placenta development GO:0001892 1 0.018
meiosis i GO:0007127 4 0.018
oxidation reduction process GO:0055114 396 0.018
negative regulation of gliogenesis GO:0014014 3 0.018
lipid transport GO:0006869 90 0.018
sodium ion export GO:0071436 7 0.018
cerebellar cortex development GO:0021695 1 0.018
regulation of meiosis GO:0040020 3 0.018
neuron projection development GO:0031175 106 0.018

DNMT3B disease predictions

Disease DO term ID Size Probability Func Analog Org
peripheral neuropathy DOID:0060053 12 0.359
nervous system disease DOID:863 431 0.359
neuropathy DOID:870 52 0.359
hereditary sensory neuropathy DOID:0050548 12 0.064
physical disorder DOID:0080015 41 0.036
musculoskeletal system disease DOID:17 223 0.020