|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
1.000
|
|
|
|
dna replication
|
GO:0006260 |
116 |
1.000
|
Fly |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.999
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.999
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.999
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.997
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.996
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.996
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.994
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.993
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.990
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.989
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.987
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.983
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.971
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.968
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.967
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.964
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.964
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.964
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.958
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.958
|
Worm Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.956
|
Fly |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.953
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.938
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.938
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.932
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.919
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.916
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.902
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.900
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.895
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.890
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.888
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.882
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.880
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.875
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.875
|
Fly |
|
|
dna packaging
|
GO:0006323 |
77 |
0.823
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.815
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.814
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.807
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.806
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.795
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.779
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.756
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.751
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.743
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.723
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.708
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.707
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.697
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.690
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.687
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.652
|
|
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.650
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.635
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.626
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.623
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.621
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.614
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
12 |
0.606
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.603
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.601
|
Fly |
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.589
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.587
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.559
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.555
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.555
|
Fly |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.554
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.548
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.547
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.541
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.535
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.532
|
Rat |
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.515
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.514
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.512
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.506
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.505
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.502
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.493
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.491
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.484
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.478
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.459
|
Fly |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.458
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.457
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.455
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.452
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.452
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.452
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.449
|
Worm |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.443
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.430
|
Fly |
|
|
blood circulation
|
GO:0008015 |
113 |
0.418
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.415
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.414
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.406
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.403
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.400
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.393
|
Rat Fly |
|
|
cohesin localization to chromatin
|
GO:0071921 |
4 |
0.390
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.387
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.385
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.383
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.381
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.381
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.379
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.378
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.368
|
Rat Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.366
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.361
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.345
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.339
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.338
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.328
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.323
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.314
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.309
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.306
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.306
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.305
|
Mouse Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.304
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.301
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.297
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.288
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.282
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.281
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.277
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.257
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.257
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.256
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.253
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.251
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.244
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.240
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.237
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.235
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.234
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.230
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.225
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.209
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.205
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.204
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.197
|
Fly |
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.194
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.191
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.191
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.191
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.189
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.182
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.180
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.175
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.173
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.170
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
6 |
0.170
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.169
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.168
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.168
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.161
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.160
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.159
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.148
|
Worm |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.146
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.143
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.143
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.139
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.137
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.137
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.136
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.136
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.135
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.135
|
Mouse Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.135
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.134
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.134
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.133
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.131
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.128
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.128
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.127
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.122
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.121
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.119
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.119
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.119
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.118
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.117
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.116
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.116
|
Fly |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.115
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.114
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.111
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.110
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.110
|
Fly |
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.109
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.109
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.109
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.109
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.108
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.108
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.107
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.105
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.104
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.104
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.104
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.104
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.104
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.103
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.101
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.100
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.100
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.099
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.098
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.098
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.097
|
|
|
|
head development
|
GO:0060322 |
108 |
0.096
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.096
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.096
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.094
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.092
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.092
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.092
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.091
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.090
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.090
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.089
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.088
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.088
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.088
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.088
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.085
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.084
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.083
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.082
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.082
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.081
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.081
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.081
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.081
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.080
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.078
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.078
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.077
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.077
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.075
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.075
|
Rat Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.075
|
Fly |
|
|
telencephalon development
|
GO:0021537 |
17 |
0.075
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.074
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.074
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.074
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.074
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.073
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.073
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.072
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.071
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.071
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.070
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.070
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.069
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.068
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.067
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.067
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.067
|
Fly |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.066
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.066
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.066
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.065
|
Fly |
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.065
|
Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.064
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.064
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.064
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.063
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.063
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.063
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.062
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.060
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.060
|
Rat Fly |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.060
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.060
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.059
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.059
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.058
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.058
|
|
|
|
mitotic dna replication checkpoint
|
GO:0033314 |
2 |
0.058
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.058
|
Fly |
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.058
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.057
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.057
|
|
|
|
non recombinational repair
|
GO:0000726 |
14 |
0.057
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.057
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.056
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.056
|
Rat |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.055
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
15 |
0.055
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.054
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.054
|
Fly |
|
|
gene silencing
|
GO:0016458 |
49 |
0.054
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.054
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.054
|
Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.053
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.053
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.052
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.052
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.052
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.051
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.051
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.050
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.048
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.048
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.047
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.047
|
Mouse |
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.047
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.047
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.047
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.046
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.046
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.046
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.046
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.045
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.045
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.044
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.044
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.044
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.044
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.044
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.044
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.043
|
Fly |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.043
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.043
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.043
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
6 |
0.043
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.043
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.043
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.042
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.042
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.042
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.042
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.041
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.041
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.041
|
Mouse |
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.041
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.041
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.041
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.040
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.040
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.040
|
Fly |
|
|
reproduction
|
GO:0000003 |
63 |
0.040
|
Rat Fly |
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.039
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.039
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.039
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.039
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.039
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.039
|
Fly |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.039
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.038
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.038
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.038
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.038
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.038
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.038
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.037
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.037
|
Fly |
|
|
developmental maturation
|
GO:0021700 |
28 |
0.037
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.036
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.036
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.036
|
Fly |
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.036
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.035
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.035
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.035
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.035
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.035
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.035
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.035
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.035
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.035
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.035
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.035
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.034
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.034
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.034
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.034
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.034
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.034
|
Rat |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.033
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.033
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.033
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.032
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.032
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.032
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
6 |
0.032
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.032
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.032
|
|
|
|
negative regulation of translation
|
GO:0017148 |
37 |
0.032
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.032
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.031
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.031
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.031
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.031
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.031
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.030
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.030
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.030
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.030
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.029
|
Rat Fly |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.029
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.029
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.029
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.029
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.028
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.028
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
12 |
0.027
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.027
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.027
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.027
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.026
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.026
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.026
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.026
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.026
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.026
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.026
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.025
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.025
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.025
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.025
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.025
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.025
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.025
|
Fly |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.025
|
Rat |
|
|
regionalization
|
GO:0003002 |
29 |
0.024
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.024
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.024
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.024
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.024
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.024
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.024
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.024
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.024
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.023
|
Mouse |
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.023
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.023
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.023
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.023
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.023
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.022
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.022
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.022
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.022
|
|
|
|
chromosome localization
|
GO:0050000 |
20 |
0.022
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.022
|
Mouse |
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.022
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.022
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.022
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.021
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.021
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.021
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.021
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.021
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.021
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.021
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.021
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.021
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.020
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.020
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.020
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.020
|
Fly |
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
2 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.019
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.019
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.019
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.019
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.019
|
|
