Homo sapiens

0 known processes

HLA-F

major histocompatibility complex, class I, F

(Aliases: HLA-CDA12,HLA-5.4,CDA12,HLAF)

HLA-F biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception GO:0050907 33 1.000
Human
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 1.000
Human
regulation of regulatory t cell differentiation GO:0045589 4 1.000
Human
antigen processing and presentation via mhc class ib GO:0002475 3 1.000
Human
sensory perception of bitter taste GO:0050913 28 1.000
Human
detection of external biotic stimulus GO:0098581 19 1.000
Human
positive regulation of natural killer cell mediated immunity GO:0002717 12 1.000
Human
detection of chemical stimulus GO:0009593 55 1.000
Human
sensory perception of chemical stimulus GO:0007606 38 0.999
Human
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.999
Human
antigen processing and presentation of peptide antigen GO:0048002 18 0.999
Human
sensory perception of taste GO:0050909 36 0.998
Human
negative regulation of t cell proliferation GO:0042130 8 0.997
Human
positive regulation of lymphocyte differentiation GO:0045621 13 0.996
Human
regulation of dendritic cell differentiation GO:2001198 3 0.995
Human
dendritic cell differentiation GO:0097028 13 0.994
Human
positive regulation of regulatory t cell differentiation GO:0045591 3 0.993
Human
positive regulation of t cell tolerance induction GO:0002666 2 0.987
Human
detection of biotic stimulus GO:0009595 21 0.985
Human
negative regulation of leukocyte mediated cytotoxicity GO:0001911 5 0.983
Human
immune response inhibiting signal transduction GO:0002765 4 0.981
Human
negative regulation of leukocyte mediated immunity GO:0002704 14 0.980
Human
antigen processing and presentation of endogenous antigen GO:0019883 7 0.975
Human
detection of other organism GO:0098543 13 0.972
Human
iron ion import into cell GO:0097459 2 0.969
Human
positive regulation of cytokine production GO:0001819 167 0.960
Human
lymphocyte mediated immunity GO:0002449 48 0.941
Human
natural killer cell mediated immunity GO:0002228 23 0.929
Human
positive regulation of tolerance induction GO:0002645 2 0.910
Human
positive regulation of leukocyte activation GO:0002696 80 0.908
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.901
Human
detection of stimulus GO:0051606 85 0.900
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.898
Human
negative regulation of dendritic cell differentiation GO:2001199 2 0.896
Human
leukocyte proliferation GO:0070661 74 0.886
Human
t cell tolerance induction GO:0002517 4 0.879
Human
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.878
Human
positive regulation of interferon gamma production GO:0032729 26 0.873
Human
antigen processing and presentation GO:0019882 33 0.870
Human
regulation of t cell activation GO:0050863 77 0.867
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 5 0.863
Human
regulation of leukocyte proliferation GO:0070663 67 0.860
Human
regulation of lymphocyte proliferation GO:0050670 64 0.851
Human
regulation of cell killing GO:0031341 22 0.838
Human
positive regulation of t cell activation GO:0050870 54 0.833
Human
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.831
Human
regulation of cytokine production GO:0001817 232 0.829
Human
retina homeostasis GO:0001895 42 0.828
Human
regulation of t cell tolerance induction GO:0002664 4 0.816
Human
positive regulation of cell activation GO:0050867 81 0.806
Human
positive regulation of leukocyte differentiation GO:1902107 37 0.804
Human
mononuclear cell proliferation GO:0032943 71 0.800
Human
positive regulation of memory t cell activation GO:2000568 1 0.774
Human
lymphocyte proliferation GO:0046651 70 0.770
Human
positive regulation of t cell differentiation GO:0045582 11 0.765
Human
immune effector process GO:0002252 159 0.761
Human
positive regulation of leukocyte mediated immunity GO:0002705 24 0.756
Human
regulation of adaptive immune response GO:0002819 33 0.755
Human
interferon gamma production GO:0032609 39 0.741
Human
regulation of cell activation GO:0050865 125 0.739
Human
negative regulation of cell proliferation GO:0008285 228 0.731
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.731
Human
regulation of leukocyte activation GO:0002694 115 0.730
Human
system process GO:0003008 349 0.729
Human
metal ion transport GO:0030001 272 0.712
Human
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 6 0.682
Human
t cell proliferation GO:0042098 45 0.667
Human
regulation of t cell mediated cytotoxicity GO:0001914 8 0.646
Human
cell killing GO:0001906 34 0.643
Human
detection of bacterium GO:0016045 13 0.622
Human
natural killer cell mediated cytotoxicity GO:0042267 23 0.620
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.618
protection from natural killer cell mediated cytotoxicity GO:0042270 3 0.617
Human
regulation of lymphocyte activation GO:0051249 103 0.615
Human
positive regulation of lymphocyte activation GO:0051251 73 0.612
Human
positive regulation of adaptive immune response GO:0002821 21 0.607
Human
t cell activation GO:0042110 99 0.603
Human
positive regulation of cell killing GO:0031343 19 0.585
Human
immune response regulating signaling pathway GO:0002764 97 0.566
Human
regulation of natural killer cell mediated immunity GO:0002715 16 0.563
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independent GO:0002486 3 0.560
Human
sensory perception GO:0007600 103 0.556
Human
cation transport GO:0006812 331 0.553
Human
regulation of leukocyte differentiation GO:1902105 61 0.548
Human
cell activation GO:0001775 213 0.547
Human
positive regulation of immune response GO:0050778 159 0.534
Human
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.534
Human
innate immune response GO:0045087 178 0.526
Human
interleukin 12 production GO:0032615 15 0.506
Human
leukocyte mediated cytotoxicity GO:0001909 27 0.505
Human
regulation of interferon gamma production GO:0032649 36 0.503
Human
regulation of immune response GO:0050776 201 0.500
Human
tissue homeostasis GO:0001894 63 0.499
Human
inorganic ion import into cell GO:0099587 2 0.494
Human
lymphocyte activation GO:0046649 133 0.488
Human
negative regulation of leukocyte differentiation GO:1902106 24 0.480
Human
negative regulation of immune system process GO:0002683 136 0.479
Human
defense response GO:0006952 315 0.476
Human
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.472
Human
detection of stimulus involved in sensory perception GO:0050906 43 0.470
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.468
Human
regulation of tolerance induction GO:0002643 4 0.467
Human
leukocyte mediated immunity GO:0002443 59 0.463
Human
regulation of leukocyte mediated immunity GO:0002703 38 0.454
Human
t cell mediated immunity GO:0002456 25 0.441
Human
biological adhesion GO:0022610 331 0.424
Human
response to other organism GO:0051707 261 0.421
Human
cytokine production GO:0001816 247 0.419
Human
negative regulation of leukocyte activation GO:0002695 26 0.419
Human
positive regulation of immune system process GO:0002684 283 0.416
Human
negative regulation of developmental process GO:0051093 247 0.416
Human
transition metal ion transport GO:0000041 23 0.415
Human
regulation of interleukin 12 production GO:0032655 15 0.411
Human
hemopoiesis GO:0030097 180 0.410
Human
anatomical structure homeostasis GO:0060249 100 0.410
Human
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.409
Human
t cell mediated cytotoxicity GO:0001913 9 0.404
Human
response to bacterium GO:0009617 144 0.402
Human
regulation of immune effector process GO:0002697 91 0.400
Human
negative regulation of multicellular organismal process GO:0051241 317 0.392
Human
tolerance induction GO:0002507 6 0.384
Human
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 2 0.379
Human
regulation of t cell proliferation GO:0042129 42 0.367
Human
leukocyte activation GO:0045321 164 0.364
Human
response to external biotic stimulus GO:0043207 261 0.357
Human
leukocyte differentiation GO:0002521 98 0.357
Human
positive regulation of cell differentiation GO:0045597 211 0.350
Human
negative regulation of leukocyte proliferation GO:0070664 16 0.348
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.346
Human
regulation of cell differentiation GO:0045595 393 0.343
Human
negative regulation of t cell activation GO:0050868 18 0.338
Human
positive regulation of developmental process GO:0051094 314 0.331
Human
positive regulation of defense response GO:0031349 87 0.321
Human
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.313
Human
regulation of lymphocyte mediated immunity GO:0002706 33 0.310
Human
negative regulation of cell differentiation GO:0045596 171 0.309
Human
regulation of lymphocyte differentiation GO:0045619 22 0.305
Human
regulation of t cell differentiation GO:0045580 19 0.298
Human
negative regulation of immune effector process GO:0002698 38 0.295
Human
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.283
Human
t cell differentiation GO:0030217 29 0.281
Human
negative regulation of lymphocyte activation GO:0051250 24 0.279
Human
adaptive immune response GO:0002250 49 0.272
Human
multicellular organismal homeostasis GO:0048871 67 0.271
Human
regulation of t cell mediated immunity GO:0002709 18 0.265
Human
immune response GO:0006955 307 0.263
Human
inorganic cation import into cell GO:0098659 2 0.253
Human
negative regulation of cell killing GO:0031342 5 0.247
Human
iron ion transport GO:0006826 12 0.244
Human
response to biotic stimulus GO:0009607 276 0.242
Human
immune system development GO:0002520 195 0.241
Human
negative regulation of defense response GO:0031348 47 0.238
Human
positive regulation of interleukin 12 production GO:0032735 8 0.235
Human
lymphocyte differentiation GO:0030098 35 0.234
Human
neurological system process GO:0050877 163 0.234
Human
positive regulation of t cell mediated immunity GO:0002711 12 0.228
Human
negative regulation of immune response GO:0050777 40 0.220
Human
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.218
Human
memory t cell activation GO:0035709 1 0.210
Human
type i interferon signaling pathway GO:0060337 11 0.207
production of molecular mediator of immune response GO:0002440 37 0.207
regulation of defense response GO:0031347 154 0.205
Human
regulation of memory t cell activation GO:2000567 1 0.195
Human
regulation of innate immune response GO:0045088 97 0.192
Human
positive regulation of immune effector process GO:0002699 40 0.189
Human
response to interferon gamma GO:0034341 39 0.187
negative regulation of lymphocyte mediated immunity GO:0002707 12 0.181
Human
cell adhesion GO:0007155 325 0.173
Human
negative regulation of mononuclear cell proliferation GO:0032945 15 0.165
Human
negative regulation of cell activation GO:0050866 33 0.150
Human
positive regulation of t cell mediated cytotoxicity GO:0001916 7 0.122
Human
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 2 0.108
Human
regulation of viral genome replication GO:0045069 48 0.101
mapk cascade GO:0000165 288 0.090
purine containing compound catabolic process GO:0072523 411 0.090
interleukin 6 production GO:0032635 37 0.084
import into cell GO:0098657 2 0.083
Human
positive regulation of innate immune response GO:0045089 79 0.079
Human
negative regulation of innate immune response GO:0045824 18 0.075
Human
secretion GO:0046903 254 0.075
regulation of secretion GO:0051046 194 0.073
negative regulation of lymphocyte proliferation GO:0050672 15 0.073
Human
secretion by cell GO:0032940 226 0.071
viral gene expression GO:0019080 35 0.071
regulation of osteoblast differentiation GO:0045667 38 0.068
ribonucleoside triphosphate catabolic process GO:0009203 391 0.062
regulation of interleukin 10 secretion GO:2001179 4 0.058
post embryonic development GO:0009791 2 0.056
cytokine production involved in immune response GO:0002367 27 0.056
immune response activating signal transduction GO:0002757 90 0.055
cytoplasmic transport GO:0016482 379 0.051
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.050
Human
cell projection organization GO:0030030 252 0.050
positive regulation of cellular amine metabolic process GO:0033240 7 0.043
purine nucleoside triphosphate catabolic process GO:0009146 392 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.042
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.040
interferon gamma biosynthetic process GO:0042095 8 0.040
regulation of protein secretion GO:0050708 86 0.039
positive regulation of secretion GO:0051047 116 0.039
intracellular protein transport GO:0006886 270 0.039
regulation of interleukin 10 production GO:0032653 16 0.038
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.038
regulation of secretion by cell GO:1903530 177 0.037
regulation of protein localization GO:0032880 296 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
cellular response to oxidative stress GO:0034599 85 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
cellular response to ammonium ion GO:0071242 4 0.034
activated t cell proliferation GO:0050798 13 0.033
response to activity GO:0014823 0 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
response to virus GO:0009615 126 0.032
negative regulation of protein secretion GO:0050709 29 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.031
cellular response to interferon gamma GO:0071346 24 0.031
positive regulation of cell proliferation GO:0008284 301 0.031
regulation of cell cycle GO:0051726 393 0.031
cellular response to oxygen containing compound GO:1901701 276 0.030
regulation of cytokine secretion GO:0050707 57 0.029
cellular amine metabolic process GO:0044106 41 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
cellular macromolecular complex assembly GO:0034622 324 0.029
defense response to other organism GO:0098542 129 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
regulation of mapk cascade GO:0043408 262 0.026
protein secretion GO:0009306 98 0.026
t cell differentiation in thymus GO:0033077 4 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.025
negative regulation of cytokine production GO:0001818 82 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
viral process GO:0016032 146 0.024
multi organism cellular process GO:0044764 156 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
defense response to virus GO:0051607 71 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
maintenance of location in cell GO:0051651 62 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.023
nucleoside catabolic process GO:0009164 408 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
negative regulation of cell death GO:0060548 345 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
ribonucleotide catabolic process GO:0009261 405 0.022
cellular response to cytokine stimulus GO:0071345 181 0.022
lipid metabolic process GO:0006629 381 0.022
cellular protein complex assembly GO:0043623 188 0.022
t cell costimulation GO:0031295 7 0.022
positive regulation of mononuclear cell proliferation GO:0032946 47 0.021
cd8 positive alpha beta t cell activation GO:0036037 3 0.021
positive regulation of protein kinase activity GO:0045860 190 0.020
regulation of protein transport GO:0051223 213 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.019
positive regulation of t cell proliferation GO:0042102 33 0.019
cytokine secretion GO:0050663 64 0.019
organophosphate catabolic process GO:0046434 430 0.019
response to type i interferon GO:0034340 14 0.019
regulation of kinase activity GO:0043549 314 0.019
regulation of ion transport GO:0043269 189 0.019
pattern recognition receptor signaling pathway GO:0002221 48 0.018
response to oxygen containing compound GO:1901700 369 0.018
female gamete generation GO:0007292 2 0.018
amine metabolic process GO:0009308 44 0.018
rna catabolic process GO:0006401 71 0.018
action potential GO:0001508 34 0.018
mitotic cell cycle process GO:1903047 286 0.018
positive regulation of cell death GO:0010942 263 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
cytokine biosynthetic process GO:0042089 37 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
nitrogen compound transport GO:0071705 191 0.017
cellular protein catabolic process GO:0044257 261 0.016
regulatory t cell differentiation GO:0045066 5 0.016
Human
positive regulation of response to external stimulus GO:0032103 88 0.016
multicellular organismal aging GO:0010259 3 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
interaction with host GO:0051701 42 0.016
cell morphogenesis GO:0000902 296 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
detection of peptidoglycan GO:0032499 1 0.015
interleukin 10 production GO:0032613 17 0.015
regulation of transmembrane transport GO:0034762 139 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
entry into host cell GO:0030260 25 0.014
determination of adult lifespan GO:0008340 2 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
cell development GO:0048468 328 0.014
positive regulation of secretion by cell GO:1903532 108 0.014
negative regulation of secretion GO:0051048 58 0.014
detection of muramyl dipeptide GO:0032498 1 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
positive regulation of leukocyte proliferation GO:0070665 48 0.014
regulation of transferase activity GO:0051338 355 0.014
cellular homeostasis GO:0019725 196 0.013
viral life cycle GO:0019058 132 0.013
oogenesis GO:0048477 2 0.013
negative regulation of viral process GO:0048525 66 0.013
regulation of cell migration GO:0030334 289 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
negative regulation of cell cycle GO:0045786 193 0.013
activation of immune response GO:0002253 114 0.013
myoblast fusion GO:0007520 1 0.013
positive regulation of transport GO:0051050 336 0.013
nucleotide catabolic process GO:0009166 408 0.013
negative regulation of antigen processing and presentation GO:0002578 5 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.012
negative regulation of multi organism process GO:0043901 92 0.012
blastoderm segmentation GO:0007350 2 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of lymphocyte proliferation GO:0050671 46 0.012
neuron development GO:0048666 113 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
negative regulation of catalytic activity GO:0043086 335 0.012
divalent metal ion transport GO:0070838 152 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
viral transcription GO:0019083 35 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
t cell selection GO:0045058 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
multi organism metabolic process GO:0044033 41 0.011
mitotic cell cycle GO:0000278 326 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
regulation of proteolysis GO:0030162 293 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
amide transport GO:0042886 76 0.010
interspecies interaction between organisms GO:0044419 156 0.010
cell projection assembly GO:0030031 126 0.010
cellular amino acid metabolic process GO:0006520 116 0.010
ossification GO:0001503 121 0.010
regulation of alpha beta t cell activation GO:0046634 13 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010

HLA-F disease predictions

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 13 0.562
Human
disease by infectious agent DOID:0050117 34 0.562
Human
viral infectious disease DOID:934 13 0.562
Human
human immunodeficiency virus infectious disease DOID:526 13 0.562
Human
musculoskeletal system disease DOID:17 223 0.555
skin disease DOID:37 33 0.324
Human
integumentary system disease DOID:16 43 0.324
Human
primary immunodeficiency disease DOID:612 36 0.113
severe combined immunodeficiency DOID:627 10 0.113
combined t cell and b cell immunodeficiency DOID:628 12 0.113
immune system disease DOID:2914 155 0.113
bone disease DOID:0080001 88 0.023
connective tissue disease DOID:65 109 0.023
disease of cellular proliferation DOID:14566 174 0.013