IMP

Process View

Homo sapiens

11 genes annotated in human

Multi-species View

positive regulation of t cell differentiation

GO:0045582

Any process that activates or increases the frequency, rate or extent of T cell differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
B2M	beta-2-microglobulin	0.824
HLA-G	major histocompatibility complex, class I, G	0.776
HLA-F	major histocompatibility complex, class I, F	0.765	Human
HLA-B	major histocompatibility complex, class I, B	0.680
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.657	Human
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.641
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.618
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.559
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.422
HLA-C	major histocompatibility complex, class I, C	0.392	Human
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.325	Mouse
HLA-A	major histocompatibility complex, class I, A	0.308	Human
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.267
LIN9	lin-9 homolog (C. elegans)	0.242
CD247	CD247 molecule	0.236
HLA-DMB	major histocompatibility complex, class II, DM beta	0.230
HLA-E	major histocompatibility complex, class I, E	0.215	Human
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.174
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.149	Mouse
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.120
PILRA	paired immunoglobin-like type 2 receptor alpha	0.104
CXCR4	chemokine (C-X-C motif) receptor 4	0.093
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.084
IL4R	interleukin 4 receptor	0.082	Mouse
BIRC3	baculoviral IAP repeat containing 3	0.070
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.067
CD2	CD2 molecule	0.062
MED25	mediator complex subunit 25	0.060
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.057
IL2RB	interleukin 2 receptor, beta	0.055
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.055	Human
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.053
IL4	interleukin 4	0.050
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.048
LCK	lymphocyte-specific protein tyrosine kinase	0.046	Mouse
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.045
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.045
IL1R1	interleukin 1 receptor, type I	0.041
IL6R	interleukin 6 receptor	0.036
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.036
IL1B	interleukin 1, beta	0.033	Rat
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.032
SIGLEC7	sialic acid binding Ig-like lectin 7	0.029
IL8	interleukin 8	0.029
RXRA	retinoid X receptor, alpha	0.029
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.028
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.024
LIN54	lin-54 homolog (C. elegans)	0.023
NCOR2	nuclear receptor corepressor 2	0.022
NOD2	nucleotide-binding oligomerization domain containing 2	0.022
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.022
BTN3A1	butyrophilin, subfamily 3, member A1	0.022
LAT	linker for activation of T cells	0.021
PLAUR	plasminogen activator, urokinase receptor	0.018
ICAM1	intercellular adhesion molecule 1	0.018
CD48	CD48 molecule	0.017
CXCL2	chemokine (C-X-C motif) ligand 2	0.017
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.017
TGFB3	transforming growth factor, beta 3	0.017
EGR2	early growth response 2	0.016
TGFB1	transforming growth factor, beta 1	0.016
EPOR	erythropoietin receptor	0.016
CTBP1	C-terminal binding protein 1	0.015
NLRP3	NLR family, pyrin domain containing 3	0.015
SLAMF1	signaling lymphocytic activation molecule family member 1	0.014
CSK	c-src tyrosine kinase	0.014
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.014
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.014
TRAF1	TNF receptor-associated factor 1	0.014
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.013
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.013
CXCL3	chemokine (C-X-C motif) ligand 3	0.013
STAP2	signal transducing adaptor family member 2	0.013
NOD1	nucleotide-binding oligomerization domain containing 1	0.013
BTN2A2	butyrophilin, subfamily 2, member A2	0.013	Mouse
BTN3A2	butyrophilin, subfamily 3, member A2	0.013
CCR7	chemokine (C-C motif) receptor 7	0.013
EGR1	early growth response 1	0.013
IL2RG	interleukin 2 receptor, gamma	0.013	Mouse
CCL20	chemokine (C-C motif) ligand 20	0.012
SH2D2A	SH2 domain containing 2A	0.012
JAK1	Janus kinase 1	0.012
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.012
INSR	insulin receptor	0.012
CD40	CD40 molecule, TNF receptor superfamily member 5	0.011
HCP5	HLA complex P5	0.011
CD86	CD86 molecule	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
TPP1	tripeptidyl peptidase I	0.011
SOD2	superoxide dismutase 2, mitochondrial	0.011
BTN3A3	butyrophilin, subfamily 3, member A3	0.011
NCOA1	nuclear receptor coactivator 1	0.010
PPARA	peroxisome proliferator-activated receptor alpha	0.010