IMP

Process View

Homo sapiens

8 genes annotated in human

Multi-species View

negative regulation of t cell proliferation

GO:0042130

Any process that stops, prevents or reduces the rate or extent of T cell proliferation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of t cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of t cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-C	major histocompatibility complex, class I, C	1.000	Human
HLA-A	major histocompatibility complex, class I, A	0.999	Human
B2M	beta-2-microglobulin	0.999
HLA-B	major histocompatibility complex, class I, B	0.998
HLA-G	major histocompatibility complex, class I, G	0.997
HLA-F	major histocompatibility complex, class I, F	0.997	Human
CD80	CD80 molecule	0.973
HLA-E	major histocompatibility complex, class I, E	0.872	Human
CCL4	chemokine (C-C motif) ligand 4	0.819	Human
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.594
CD86	CD86 molecule	0.591
CCL2	chemokine (C-C motif) ligand 2	0.568	Human
CCR5	chemokine (C-C motif) receptor 5	0.567
PILRA	paired immunoglobin-like type 2 receptor alpha	0.522
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.497
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.404	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.397
ICAM1	intercellular adhesion molecule 1	0.330
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.287
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.269	Human
CCL5	chemokine (C-C motif) ligand 5	0.255	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.252
IL8	interleukin 8	0.243
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.243
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.233
CXCL10	chemokine (C-X-C motif) ligand 10	0.214
CCL8	chemokine (C-C motif) ligand 8	0.192	Human
IL1B	interleukin 1, beta	0.174
TRAF1	TNF receptor-associated factor 1	0.172
TAPBP	TAP binding protein (tapasin)	0.162
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.148
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.125
CCL13	chemokine (C-C motif) ligand 13	0.119	Human
HLA-DMB	major histocompatibility complex, class II, DM beta	0.112
FSTL1	follistatin-like 1	0.111
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.105
CXCL3	chemokine (C-X-C motif) ligand 3	0.099
CCR1	chemokine (C-C motif) receptor 1	0.096
CXCL2	chemokine (C-X-C motif) ligand 2	0.093
CCR7	chemokine (C-C motif) receptor 7	0.092
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.091
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.086
APAF1	apoptotic peptidase activating factor 1	0.084
IL6	interleukin 6 (interferon, beta 2)	0.080
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.074
CCL7	chemokine (C-C motif) ligand 7	0.072	Human
ADAM17	ADAM metallopeptidase domain 17	0.069
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.065
DPP4	dipeptidyl-peptidase 4	0.063
PLK3	polo-like kinase 3	0.059
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.059
IL10	interleukin 10	0.056
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.055	Human
IDE	insulin-degrading enzyme	0.053
XIAP	X-linked inhibitor of apoptosis	0.052
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.051
CXCL11	chemokine (C-X-C motif) ligand 11	0.050
FPR3	formyl peptide receptor 3	0.044
BIRC3	baculoviral IAP repeat containing 3	0.041
APP	amyloid beta (A4) precursor protein	0.040
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.037
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.036
BTN3A1	butyrophilin, subfamily 3, member A1	0.034
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.033
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.031	Human
IL2RB	interleukin 2 receptor, beta	0.030
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.030
IFNG	interferon, gamma	0.028
PTAFR	platelet-activating factor receptor	0.028
HK3	hexokinase 3 (white cell)	0.027
SIGLEC7	sialic acid binding Ig-like lectin 7	0.024
CD83	CD83 molecule	0.023
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.023
CDK6	cyclin-dependent kinase 6	0.022
TREM1	triggering receptor expressed on myeloid cells 1	0.021
CCL22	chemokine (C-C motif) ligand 22	0.020	Human
C3	complement component 3	0.020
UBD	ubiquitin D	0.020
IL21R	interleukin 21 receptor	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
EBI3	Epstein-Barr virus induced 3	0.019
CFLAR	CASP8 and FADD-like apoptosis regulator	0.018
CXCL5	chemokine (C-X-C motif) ligand 5	0.018
CCL20	chemokine (C-C motif) ligand 20	0.018	Human
CD2	CD2 molecule	0.018
NLRP3	NLR family, pyrin domain containing 3	0.017
CD40	CD40 molecule, TNF receptor superfamily member 5	0.017
IER3	immediate early response 3	0.017
TYMP	thymidine phosphorylase	0.016
CD163	CD163 molecule	0.016
CXCL13	chemokine (C-X-C motif) ligand 13	0.016
BCL2A1	BCL2-related protein A1	0.016
TNF	tumor necrosis factor	0.016
TAPBPL	TAP binding protein-like	0.016
ZFYVE9	zinc finger, FYVE domain containing 9	0.015
CD28	CD28 molecule	0.015
IL10RA	interleukin 10 receptor, alpha	0.014
SLAMF8	SLAM family member 8	0.014
ENG	endoglin	0.014
CCL3	chemokine (C-C motif) ligand 3	0.013	Human
BTN2A2	butyrophilin, subfamily 2, member A2	0.012	Mouse
IL2RA	interleukin 2 receptor, alpha	0.012	Mouse
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.012	Human Rat
CCL19	chemokine (C-C motif) ligand 19	0.012	Human
SLAMF7	SLAM family member 7	0.011
BTN3A3	butyrophilin, subfamily 3, member A3	0.011
CH25H	cholesterol 25-hydroxylase	0.011
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.011
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.010
CCR4	chemokine (C-C motif) receptor 4	0.010
CCND1	cyclin D1	0.010
ADAMDEC1	ADAM-like, decysin 1	0.010